Our cover story: The twice-yearly injectable, which significantly reduces HIV incidence compared with oral regimens, has high adherence and manageable adverse effects.

The COVID-19 pandemic intensified long-standing problems in scientific production and communication—driven by perverse academic incentives, peer review strain, media hype, and growing misuse of AI—highlighting the urgent need for stronger critical appraisal skills across research and medicine.

Read SIDP's column on the next-generation antifungals as well as combination therapeutics for Candida auris, and the Clinical and Laboratory Standards Institute Subcommittee on Antimicrobial Susceptibility Testing breakpoint recommendations. www.contagionlive.com/view/top-inf...

This week, read SIDP's column on the next-generation antifungals as well as combination therapeutics for Candida auris, the Clinical and Laboratory Standards Institute Subcommittee on Antimicrobial Susceptibility Testing breakpoint recommendations, and more. #IDsky #Medsky

In the latest Bench to Bedside column from the @sidpharm.bsky.social Dr. Tina Zheng and Dr. Dallas Smith provide an overview of some of the next-generation antifungals as well as combination therapeutics. #IDsky #Medsky

From our latest issue: Here are the highlights from the CLSI Subcommittee's work including the removal of doxycycline and tetracycline breakpoints, the revision of aminoglycoside breakpoints for Acinetobacter spp, and addition of aztreonam-avibactam breakpoints for Enterobacterales. #Idsky

Sharon Carrasco DNP, APRN, ACNS-BC, ANP-C, CEN, FAEN, FAAN, FNAP, discusses her approach to training for these care scenarios. #IDsky #Medsky

In our current issue: William DePasquale, PharmD, discusses a recent study challenges the need for high-dose trimethoprim-sulfamethoxazole in managing Stenotrophomonas maltophilia pneumonia, finding lower doses may offer comparable efficacy. #IDsky #Medsky

From our latest issue: Dr. Liz Walters discusses a recent study, which examined how rurality and the availability of post discharge follow-up influence clinicians’ decisions on antibiotic duration at discharge for patients hospitalized with community-acquired pneumonia. #IDsky #Medsky

With rates of influenza vaccination in decline, two health systems evaluated interventions for prompting clinicians to order, and patients to obtain flu shots. #IDsky #Medsky

Former FDA Chief Scientist, Jesse L. Goodman, MD, MPH, provides insights on the potential consequences of these new recommendations. #IDsky #Medsky

Sharon Carrasco DNP, APRN, ACNS-BC, ANP-C, CEN, FAEN, FAAN, FNAP, talks about safely responding to deadly pathogens such as Ebola and Lassa fever, and where the US is in terms of thinking about preparedness on a national level. #IDsky #Medsky

#Breaking New federal guidance recommends childhood vaccines for 11 diseases downsizing immunization protection from the previous list of 18 diseases. #IDsky #Medsky www.contagionlive.com/view/us-comp...

A delay in providing standard infant vaccinations is associated with children not receiving MMR (measles, mumps, rubella) vaccine by 2 years of age.

[email protected] discusses the series of politically driven actions, including defunding mRNA research, dismantling vaccine advisory bodies, and restricting CDC recommendations, that have undermined vaccine access, but professional societies, states are stepping in to preserve public health.

Read about increasing influenza activity, an approach to de-escalating empiric broad spectrum antibiotics for clinically stable patients with community-onset sepsis, and more.

Jill Morgan, RN, BSN, talks about steps being taken to ensure everyone’s safety is front of mind. #IDsky #Medsky

CDC surveillance shows sharp week-over-week increases in influenza test positivity, outpatient illness, and hospital admissions, with A(H3N2) continuing to predominate nationwide. #IDsky #Medsky

Jill Morgan, RN, BSN, reviews this significant part of clinical care and how personal protective equipment (PPE) is essential to protecting healthcare workers. #IDsky #medsky

The recent CDC ACIP meetings and subsequent actions show a path for which the current Health and Human Services department wants to roll back access to vaccines for this virus and other vaccines. #IDsky #Medsky

Emory's Gavin Harris, MD, discusses these elements, and how despite the fact they rarely occur, the need to do continuous training is essential for readiness. #IDsky #Medsky

Shortening course of empiric broad spectrum antibiotics for community-onset sepsis was associated with fewer days of antibiotics and hospitalization and no increase in mortality. #IDsky #Medsky

This week, check out our Media Day coverage from Emory, the WHO report on malaria, and more. #IDsky #Medsky www.contagionlive.com/view/top-inf...

In the final installment of the series, psychiatrist Robert C Bransfield, MD, outlines how interdisciplinary research, education, and policy could help reduce infection-associated neuropsychiatric impairment and violence.

In the second installment of this 2-part article on the WHO 2025 World Malaria Report, the authors point out the positive trends in the scaling up of prevention efforts with new-generation anti-mosquito netting, vaccines and periodic chemoprevention. www.contagionlive.com/view/who-fin...

The WHO 2025 World Malaria Report adds several countries to those certified as malaria free, while recognizing spread of antimalarial drug resistance.

Amy Colson, MD, MPH, discusses phase 2 data showing durable virologic suppression, low resistance risk, and favorable safety with weekly oral islatravir plus lenacapavir in suppressed adults with HIV.

Dr. Gavin Harris discusses his experience working in outbreak environments where there is high-consequence infectious disease and how it is important to establish buy-in from the local populations and some of the important elements of what you need to leave behind when an outbreak is declared over.

Agreement supports commercialization and reimbursement efforts for tobevibart plus elebsiran as the ECLIPSE clinical program advances, including completion of enrollment for the ECLIPSE 3 trial.

#ICYMI: The Fall/Winter issue is out! Read further about lenacapavir's role in PrEP, the 2025 CLSI Subcommittee recommendations for antimicrobial susceptibility testing, an update on non–carbapenemase-producing carbapenem-resistant Enterobacterales, and more. www.contagionlive.com/view/contagi...

The single-source award will fund a large randomized trial evaluating mortality, morbidity, and developmental outcomes following the hepatitis B birth dose, amid ongoing debate over non-specific vaccine effects.

Our Fall/Winter issue is out! Read the latest in infectious disease including lenacapavir's role in PrEP, the 2025 CLSI Subcommittee recommendations for antimicrobial susceptibility testing, and more. Check out the issue here: www.contagionlive.com/view/contagi...

This week, learn more about Emory's approach around treating high-consequence infectious diseases such as Ebola, a UNC researcher's work in sequencing syphilis genomes in the search to develop a global vaccine, how the US is in danger of losing its elimination status for measles, and more.

Emory's Gavin Harris, MD, talks about taking care of patients with high-consequence infectious diseases, and working with other healthcare facilities around COVID-19 care and educating them through Emory's ECHO program on new and existing threats.

Zandraetta Tims-Cook, MD, MPH, AAHIVS, discusses access challenges, missed-dose management, and scalable care models for cabotegravir PrEP in women.

CDC reports over 1,900 confirmed cases and 49 outbreaks nationwide, with recent surges reported in South Carolina, Utah, Arizona, and Connecticut amid declining childhood vaccination coverage. www.contagionlive.com/view/us-meas...

Jonathan Parr, MD, MPH, discusses his work in locating potential targets to develop a syphilis vaccine and the challenges associated with genomic diversity of subpopulations of the main pathogen, Treponema pallidum. #IDsky #Medsky

A Nature Microbiology study shows that structure-guided bile acid design can lock Clostridioides difficile toxin B into an inactive conformation.

This new recommendation relates to infants born to women who test negative for hepatitis B. This is a departure from the federal agency’s previous recommendation and comes on the heels of the ACIP’s recent meeting. #IDsky #Medsky

Andrew Handel, MD, talks about transmission, differential diagnosis, treatment, and protection against it. #IDsky #Medsky

An impending deadline is coming up in early 2026. However, this can be reversible and unnecessary infections, severe disease, and deaths can be avoided. Dr. Rodney Rohde talks about incidence rates, how we got here, and strategies to increase immunizations. #IDsky #Medsky

Margaret Aldrich, MD, provides insight around this concept, addressing stewardship within this patient population, and how their institution’s collaborative work environment helps all of the department’s clinicians. www.contagionlive.com/view/caring-...

Gilead Sciences reported positive phase 3 ARTISTRY-2 results demonstrating that a once-daily single-tablet combination of bictegravir and lenacapavir is statistically noninferior to bictegravir/emtricitabine/tenofovir alafenamide tablets in virologically suppressed adults with HIV. #IDsky #Medsky

Innoviva CMO David Altarac, MD, offers further insights about the newly-approved antibiotic and its potential place in the market. #IDsky #medsky www.contagionlive.com/view/zoliflo...

This week, check out our coverage on 2 antibiotic FDA approvals, and clinicians weigh in on the ACIP recommendations on the hepatitis B virus (HBV) vaccine. #IDsky #Medsky www.contagionlive.com/view/top-inf...

#Breaking The antibiotic's approval was based from phase 3 results demonstrating noninferiority to a combination therapy. #IDsky #Medsky

Infectious disease pediatrician sharon nachman MD, talks about how the new recommendations will defer immunization, leading to negative impacts on long-term public health. www.contagionlive.com/view/a-pedia...

Excited to share our latest publication about SEP-1 metrics during the BCx shortage in the setting of enhanced BCx stewardship efforts @kcawcutt.bsky.social @ichejournal.bsky.social #IDSky www.cambridge.org/core/journal...

GSK’s David Payne, PhD, provides more information are the data from the EAGLE-1 trial. #IDsky #medsky

#Breaking The federal nod was given based from the phase 3 data of the EAGLE-1 trial, which showed noninferiority to combination therapy. This approval provides a new oral option. www.contagionlive.com/view/fda-app...