@markkhurana.bsky.social
📤 25
📥 45
📝 13
🚨 Where do new SARS-CoV-2 variants come from? Our new paper in
@natcomms.nature.com
suggests they stem from persistent infections. We found that immunosuppressed patients face a 5x higher risk of prolonged infection, with the virus mutating at an accelerated rate.
www.nature.com/articles/s41...
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Large-scale genomic surveillance reveals immunosuppression drives mutation dynamics in persistent SARS-CoV-2 infections - Nature Communications
Using Denmark’s genomic surveillance linked to health registries, the authors identify immunosuppression as a key risk factor for persistent SARS-CoV-2 infections and show these infections accumulate ...
https://www.nature.com/articles/s41467-026-74445-7
24 days ago
0
3
3
reposted by
Nature Medicine
about 2 months ago
Moritz Kramer & colleagues discuss global approaches to infectious disease analysis and modelling, emphasizing federated approaches and addressing challenges in data interoperability, equity, & trust. Part of our Focus issue on
#infectiousdiseases
.
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Global approaches to infectious disease surveillance and modeling - Nature Medicine
This Review discusses global approaches to infectious disease analysis and modeling, focusing on federated methods and addressing long-standing challenges in data interoperability, equity and trust.
http://dlvr.it/TSmFGt
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11
4
reposted by
Moritz Kraemer
about 2 months ago
Global approaches to infectious disease surveillance and modelling are complex in a fragmented world. We brought together an international team of researchers and policy makers to suggest a path forward using AI and federated/distributed frameworks.
www.nature.com/articles/s41...
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18
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Imagine a new pathogen emerges; what do we do if local data can’t legally leave its home country? We think federated approaches are the way forward! Our new Review out in
@natmed.nature.com
maps out how we can unlock global public health insights in near real-time.
www.nature.com/articles/s41...
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Global approaches to infectious disease surveillance and modeling - Nature Medicine
This Review discusses global approaches to infectious disease analysis and modeling, focusing on federated methods and addressing long-standing challenges in data interoperability, equity and trust.
https://www.nature.com/articles/s41591-026-04351-4
about 2 months ago
1
3
0
New Perspective in
@natcardiovascres.nature.com
maps ischemic heart disease burden against healthcare system readiness across all 47 countries in sub-Saharan Africa. The pattern is stark: countries carrying the highest burden are consistently the least equipped to respond.
doi.org/10.1038/s441...
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Ischemic heart disease burden and healthcare system readiness across sub-Saharan Africa - Nature Cardiovascular Research
Khurana et al. share their perspective on healthcare system preparedness in sub-Saharan Africa in light of the recent increase in ischemic heart disease burden, highlighting areas that require interve...
https://doi.org/10.1038/s44161-026-00817-3
2 months ago
0
0
0
This week in HealthByte 049 🚀 The under-appreciated role of the thymus in cancer treatment, a novel fusion protein treats knee osteoarthritis safely, and common antibiotics leave a decade-long effect on gut health. Link here:
byteofhealth.substack.com/p/healthbyte...
3 months ago
0
0
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🚨 Does a 2nd SARS-CoV-2 infection increase
#LongCOVID
risk? Our study of 4M+ adults in Denmark found: • Reinfection increases risk, but the jump is smaller than after the 1st infection • Vaccination significantly lowers this risk Link here:
doi.org/10.1016/j.la...
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SARS-CoV-2 reinfections and subsequent risk of hospital-diagnosed post-acute sequelae in Denmark (2020–2022): a nationwide cohort study
Reinfection increases long COVID risk; however, the absolute increase after reinfection is smaller than that observed after a primary infection. Vaccination offers substantial protection against long ...
https://www.thelancet.com/journals/lanepe/article/PIIS2666-7762(26)00013-X/fulltext
6 months ago
0
0
0
reposted by
HDSAI - Health Data Science & AI, University of Copenhagen
8 months ago
Pandemic Preparedness requires deep and comprehensive understanding. If you agree and want to know more, sign up to Mark Khurana's Phd defense on 21 November at Mærsk Tower at University of Copenhagen Details 👇
healthsciences.ku.dk/phd/calendar...
🎉
@markkhurana.bsky.social
#Science
#pandemic
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PhD defence: Mark Poulsen Khurana
Large-scale phylogenetic inference and pathogen genomics in the era of SARS-CoV-2 and beyond
https://healthsciences.ku.dk/phd/calendar/q4---2025/phd-defence-mark-poulsen-khurana/
0
2
1
reposted by
Tamar Haspel
10 months ago
Terrific
@scientificdiscovery.dev
post on randomized controlled trials in
@ourworldindata.org
. Including this important chart on the impact of pre-registration. Magically, when people had to pre-register outcomes, many of the benefits disappeared.
ourworldindata.org/randomized-c...
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Moving to a walkable city adds 1,100 steps a day 🚶♂️ AI may deskill colonoscopists when used constantly 🛠️ Engineered yeast now feeds honeybees the sterols they need to thrive 🐝 All in this week's edition of HealthByte!
open.substack.com/pub/byteofhe...
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HealthByte 038
This week: Moving to a walkable city adds 1,100 steps a day, AI may deskill colonoscopists when used constantly, and engineered yeast now feeds honeybees the sterols they need to thrive.
https://open.substack.com/pub/byteofhealth/p/healthbyte-038?r=ye3vg&utm_campaign=post&utm_medium=web
11 months ago
0
0
0
This week in HealthByte 037: The brain can trigger immunity from just seeing infection, AI predicts ICU crises hours in advance, and lithium deficiency emerges as a possible Alzheimer’s trigger 🤔 Link to the newsletter here:
byteofhealth.substack.com/p/healthbyte...
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HealthByte 037
This week: The brain can trigger immunity from just seeing infection, AI predicts ICU crises hours in advance, and lithium deficiency emerges as a possible Alzheimer’s trigger.
https://byteofhealth.substack.com/p/healthbyte-037
11 months ago
0
1
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This week in HealthByte 035: Oral contraceptives show no clear liver cancer risk, neurons fuel cancer spread by donating mitochondria, and sea slugs use stolen chloroplasts for photosynthesis and nutrition.
open.substack.com/pub/byteofhe...
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HealthByte 035
This week: Oral contraceptives show no clear liver cancer risk, neurons fuel cancer spread by donating mitochondria, and sea slugs use stolen chloroplasts for photosynthesis and nutrition.
https://open.substack.com/pub/byteofhealth/p/healthbyte-035?r=ye3vg&utm_campaign=post&utm_medium=web&showWelcomeOnShare=false
about 1 year ago
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0
0
reposted by
Carl T. Bergstrom
about 1 year ago
Remember when MDPI used questionable practices to siphon traffic from big five publishers’ journals? Never thought I’d see the shoe on the other foot.
add a skeleton here at some point
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27
reposted by
HDSAI - Health Data Science & AI, University of Copenhagen
about 1 year ago
Did you remember to subscribe to A Byte of Health?
#Science
#substack
@ucph.bsky.social
byteofhealth.substack.com/p/healthbyte...
add a skeleton here at some point
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2
2
Amazing essay on how technological change is forcing us into an evolutionary bottleneck: "a period of rapid pressure that threatens cultures, customs and peoples with extinction." Highly recommend reading.
www.nytimes.com/2025/04/19/o...
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Opinion | An Age of Extinction Is Coming. Here’s How to Survive.
https://www.nytimes.com/2025/04/19/opinion/extinction-technology-culture.html
about 1 year ago
0
0
0
reposted by
MRC-UofG Centre for Virus Research
about 1 year ago
📄 NEW | Genetic Study shows that Wildlife Trade sparked COVID-19 Virus Emergence in Humans SARS-CoV-2 arrived in Wuhan too quickly for bat hosts to have carried it there.
cell.com/cell/fulltex...
gla.ac.uk/research/az/...
@davidlrobertson.bsky.social
@spyroslytras.bsky.social
@bljog.bsky.social
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The recency and geographical origins of the bat viruses ancestral to SARS-CoV and SARS-CoV-2
Recombination-aware evolutionary analyses of the entire genomes of SARS-CoV-1-like and SARS-CoV-2-like viruses indicate that SARS-CoV-1 and SARS-CoV-2 descend from bat coronaviruses that circulated as...
https://cell.com/cell/fulltext/S0092-8674(25)00353-8
1
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A whole year of newsletter'ing! One year ago, we launched A Byte of Health! Since then, our team has published 27 newsletters with over 3,400 reads 🥳 If you’re interested in concise summaries of the latest breakthroughs in health and medicine, check out the newsletter:
byteofhealth.substack.com
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A Byte of Health | Mark Khurana | Substack
A biweekly newsletter exploring the latest breakthroughs in science and medicine. Click to read A Byte of Health, a Substack publication. Launched a year ago.
https://byteofhealth.substack.com/
over 1 year ago
0
1
0
reposted by
Jonas L Juul
over 1 year ago
I am hiring PhD students and Postdocs to join me in beautiful Copenhagen. Together, we will develop data science methods to improve epidemic preparedness. Copenhagen is amazing, salary is good, we have plenty of funding, and a great community. Read more..:
candidate.hr-manager.net/ApplicationI...
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Ph.D. and postdoc positions in Data Science for epidemic preparedness at the NERDS research group
The NERDS (NEtwoRks, Data, and Society) team at the IT University of Copenhagen welcomes applications from aspiring PhD students and postdocs in the areas of Da
https://candidate.hr-manager.net/ApplicationInit.aspx?cid=119&ProjectId=181783&DepartmentId=3439&MediaId=1282
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This week in A Byte of Health 🔬 1. Western diets during pregnancy linked to ADHD & autism 2. Engineered therapeutic mitochondria may aid organ repair 3. Annual HIV prophylaxis injections show promise 🔗 Read the full HealthByte 027 newsletter here:
open.substack.com/pub/byteofhe...
#Medsky
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HealthByte 027
This week: A Western diet during pregnancy is linked to ADHD and autism in children, engineered mitochondria may support organ repair, and annual HIV prophylaxis injections show promise.
https://open.substack.com/pub/byteofhealth/p/healthbyte-027?r=ye3vg&utm_campaign=post&utm_medium=web
over 1 year ago
0
0
0
reposted by
Kyle Griffin
over 1 year ago
Despite Elon Musk's claim that the foreign aid freeze hasn't killed anyone yet, Nick Kristof finds ample evidence to the contrary. In South Sudan, HIV-positive mothers and children who lost access to lifesaving drugs have died.
www.nytimes.com/interactive/...
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Opinion | Musk Said No One Has Died Since Aid Was Cut. That Isn’t True.
A journey through the front lines of global poverty shows that when the world’s richest men slash aid for the world’s poorest children, the result is sickness, starvation and death.
https://www.nytimes.com/interactive/2025/03/15/opinion/foreign-aid-cuts-impact.html
63
1325
593
reposted by
Mathilde MB Sloth
over 1 year ago
We have raised concerns about the study methodology in a Danish study about hormonal IUDs and the risk of breast cancer in a Letter to the Editor in
@jama.com
jamanetwork.com/journals/jam...
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Breast Cancer and Levonorgestrel-Releasing Intrauterine Systems
To the Editor We are concerned that some of the methodological approaches in a recent study1 linking use of LNG-IUSs to increased risk of breast cancer may lead to spurious associations and limit the ...
https://jamanetwork.com/journals/jama/fullarticle/2831023
0
3
1
This week in our (free!) research newsletter 📰💊 1. Preserving immune function by slowing thymus aging 2. Neurons in the hypothalamus that regulate social needs 3. Aspirin's potential role in preventing cancer metastasis
byteofhealth.substack.com/p/healthbyte...
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HealthByte 026
This week: Preserving immune function by slowing thymus aging, neurons in the hypothalamus that regulate social needs, and aspirin's potential role in preventing cancer metastasis.
https://byteofhealth.substack.com/p/healthbyte-026
over 1 year ago
0
3
3
Need a quick overview of breakthroughs in medical research over the last couple of weeks? We've got you covered in our HealthBytes newsletter! Link to this week's edition:
byteofhealth.substack.com/p/healthbyte...
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HealthByte 025
This week: Vitamin D, omega-3, and exercise slow aging, reduced yellow fever vaccine doses show promise, and less frequent mammograms are as effective as annual screenings for breast cancer.
https://byteofhealth.substack.com/p/healthbyte-025
over 1 year ago
0
1
0
reposted by
Eric Topol
over 1 year ago
New
@nature.com
How
#AI
can play a pivotal role in future pandemic preparedness and mitigation, with caveats
nature.com/articles/s41...
a privilege to join this global collaborative effort led by Moritz Kraemer and Samir Bhatt
1
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reposted by
Moritz Kraemer
over 1 year ago
AI is poised to accelerate understanding in infectious diseases, but its value needs to be demonstrated through close collaboration between research, industry, society, and policy. Paper free to read:
rdcu.be/eaxEw
Summary here:
www.ox.ac.uk/news/2025-02...
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Artificial intelligence for modelling infectious disease epidemics
Nature - This Perspective considers the application to infectious disease modelling of AI systems that combine machine learning, computational statistics, information retrieval and data science.
https://rdcu.be/eaxEw
3
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reposted by
Ryan Hisner
over 1 year ago
Looking forward to digging into this. Co-authors include
@mghafari.bsky.social
&
@mugkraemer.bsky.social
. "Large-scale genomic surveillance reveals immunosuppression drives mutation dynamics in persistent SARS-CoV-2 infections"
www.medrxiv.org/content/10.1...
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https://www.medrxiv.org/content/10.1101/2025.02.10.25321987v1
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