#ThisWeekInNPP This 🔥 Hot Topic 🔥 emphasizes that ovarian hormone fluctuations - across the menstrual cycle, postpartum, & menopause - are key drivers of psychiatric risk in ♀️, yet remain understudied / @kundakoviclab.bsky.social www.nature.com/articles/s41...

Cover for 1922 first edition of Don Quijote in Mandarin by Liu Bangyi. Translated initially from English rather than Spanish as the "Adventures of a Crazy Hero".

“‘It’s very easy to assume that science is going to change organically towards equality — and what this study shows is that that’s not happening…It is an ‘important reminder for us that we need to stay vigilant in working towards equality in science’” @crsugimoto.bsky.social 🧪 #AcademicSky 👩🏽‍🔬

Authors use an elegant transgenic model to demonstrate that acute oral administration of metformin targets mitochondrial complex I to lower blood glucose. A crucial contribution to the debate about the mechanisms of action of #metformin. #metabolism #glucose doi.org/10.1126/scia...

p-hacking is primarily an academic publication phenomenon due to the incentives involved -- researchers find no evidence of p-hacking in e-commerce A/B testing because it's counterproductive to try and fool yourself alexmiller.phd/research/p-h...

Me opening my to do list today, featuring all the work I didn't do in December

Our new paper is out! Even with helmet protection, high-energy blunt trauma can lead to fatal respiratory failure. Our study maps specific brainstem injury patterns, revealing critical implications for #TBI & protection. Patterns of #vascularinjury ≠ #axonalinjury www.liebertpub.com/doi/10.1089/...

Astroglial Hmgb1 in postnatal #Astrocyte morphogenesis & #NeuroGlioVascularUnit maturation #SciArt Aldh1l1-CreERT2:Hmgb1 f/f🐭➡️ ⏬Astroglial endfeet coverage over vessels ⏬Single-cell #BranchingMorphogenesis @blacoste.bsky.social @naturecomms.bsky.social 2023 www.nature.com/articles/s41...

I am usually not fan of atlases… but this one is actually useful, as it demonstrates the value of protein-level measurements to identify functional cell states. #Brain #Development www.nature.com/articles/s41...

The National Academy of Sciences issues recommendation that NIH devote an institute focused on women’s health. Much needed but hard to imagine it will happen in this political environment. jamanetwork.com/journals/jam...

Aging may not increase permeability of the #BloodBrainBarrier, but rather its vulnerability to insults, interesting concept! link.springer.com/article/10.1...

Delighted to share an update to our preprint, reviewed at @elife.bsky.social, and now sent back for re-review. Colossal work by the team and driven home by @mathiasgua.bsky.social Quick 🧵 of what's new - www.biorxiv.org/content/10.1...

Who knew #microglia could be like starfish (extruding stomached to digest stuff outside their bodies)? Check out Microglial lysosomal synapses in murine #Alzheimers disease model. #neuroinflammation #neurodegeneration #neurosky

Working on our colonies breeding numbers and study numbers for this IACUC renewal.

Really nice paper looking at differential roles of astrocytes in stress physiology and behaviour ! www.nature.com/articles/s41...

Not checking nuclear markers like MALAT1 or intronic reads in your scRNA-seq data?🚨 We show their power to flag low-quality cells—even in top public datasets. It’s time to prioritize better QC for cleaner, more reliable genomics research! Read more: bmcgenomics.biomedcentral.com/articles/10.... 1/8

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Me ready to show how the NIH reporter works to a scientist friend #NewPI #GoodTools #GrantWritingTime

The “tradition” of kicking students out of student housing during summer and winter breaks at universities is incredibly broken. In this age of insane housing costs, many universities have become actively hostile to students, especially non-traditional students from a housing perspective.

American Campus Communities (NYSE: ACC) is a real complicating factor. University Housing used to be a subsidized accommodation to foster community amongst the students. Now it's a profit center designed to subsidize the non-revenue generating parts of the university.

Life is what happens between loads of laundry 🧺 #WeekendReflections

2 new studies on brain aging with sex-specific findings —Angiogenesis factors www.science.org/doi/10.1126/... —Loss of gray matter press.psprings.co.uk/jnnp/novembe...

A perfect reflection of societal bias that undervalues POC contributions while demanding even more from them. The real question is, who upholds this imbalance in science?

A new study in PNAS (N>20k) confirms women’s pain is taken less seriously than that of men, with women being less likely to receive pain meds and waiting 30 minutes longer to be seen in the ED. Sadly, the same reasons we treat women poorly in our society translate to how we treat women patients.

A humanized neuronal model system reveals key roles for manganese in neuronal endocytosis, calcium flux and mitochondrial bioenergetics https://www.biorxiv.org/content/10.1101/2024.11.27.625600v1

Women are often taking on non-promotable work, like mentoring & building team cohesion, that is unrecognized leadership work. Organizations should expand their definition of leadership to include such work & make it promotable. michiganross.umich.edu/news/how-can...

Ok, I don't think an #EvolutionaryNeuroscience starter pack existed already...so I have started one! This is not nearly as exhaustive as it should be, so drop your name (or the names of your colleagues) in the comments if you want to be added!🤩🙌 go.bsky.app/Q2UW2Sn

Sex matters for inflammatory responses during aging. #neuroinflammation, #neuroskyence, #neurodegeneration, #macrophage

PhD opportunity: If you're interested in how astrocytes and the meninges talk to each other and how this is affected in dementia come do your PhD with us in Edinburgh (cc: Karen Horsburgh and Ingo Schiessl)! www.findaphd.com/phds/project...

Non-native English speakers need 50% more time to write a paper When they do, they face a 2.5 times higher chance of being rejected because of language journals.plos.org/plosbiology/...

#neuroinflammation 🧵: The Journal of Neuroinflammation is discussing “what is and what isn’t neuroinflammation”? We would like to hear thoughts from any and all bksy researchers in or adjacent to #glia, #immunology, #inflammation, #neurodegeneration, #neuroimmunology, #neuroscience, #neuroskyence

Hi #astrocyte lovers! We are organizing the third edition of #AstrocyteCafe online, with FREE monthly seminars starting from January 2025...and we are looking for speakers! Speakers can be of any career stage: just send us an email with your topic to [email protected] 😍

I think it is time to admit I overestimated how much glassware I needed in the lab. I think I have beakers and glass bottles to share with the whole department. #NewPI #RookieMistakes #FirstExperiments

Paper of the year 2 👉 astrocytes, glucose, lactate, IDO1 and impressive results! 👇👇👇👇👇👇👇👇👇👇👇👇👇 www.science.org/doi/10.1126/...

This threaded discussion on sex differences in mechanisms leading to Alzheimer’s disease and neurodegeneration is worth a read. #microglia, #neuroinflammation

Latest preprint from the lab! Vascular mural cells protect the adult brain from haemorrhage but do not control the blood-brain barrier in developing zebrafish www.biorxiv.org/content/10.1...

Are you an #ECR who would like to attend a #microscopy or #bioimageanalysis training course in the next ~6 months but don't have sufficient funding, check to see if you are eligible for our JCS-FocalPlane Training Grant. Next deadline: 22 November 2024 www.biologists.com/grants/jcs-f...

I am looking for a starter pack to follow scientists working on sex differences and neuroendocrinology. Does anyone have any recommendation?

Yes, I have finally made it to the club! Thanks for the welcome :)

Call for abstracts and registration for the #gliameeting in #Marseille starts on 10 December! #glia2025 www.glia2025.eu/abstracts/

OPEN RANK #FACULTY #POSITION in #Pharmacology & #Neuroscience with expertise in #behavioral pharmacology/neuroscience of relevance to substance use disorders. Review of applications will start immediately. Target start date is Fall 2025. Come join us! Apply here: careers.umich.edu/job_detail/2...

Q: What's wrong with these plots? A: Pooling cell-level measurements across multiple runs conceals experimental reproducibility. Read more in JCB (with @fritzlaylin.bsky.social @katrinavelle.bsky.social & Dyche Mullins): rupress.org/jcb/article/...