Pitch in to join the fight: secure.actblue.com/donate/lande...

I’m running for Congress because we need leaders who will fight, not fold. I recognize this moment, and I’m ready to meet it. #FightDontFold #LanderForNYC #LanderForCongress

I wrote about the recent autism-microbiome paper, why I think it's the most important microbiome paper this year, and what it says about the field open.substack.com/pub/blekhman...

We are pleased to announce a new preprint by @mlweilert.bsky.social: “Widespread low-affinity motifs enhance chromatin accessibility and regulatory potential in mESCs” (www.biorxiv.org/content/10.1...). See summary and longer recap below: (TLDR; low-affinity motifs matter as pioneers!)

🧪hey all, a friend and colleague, @maddoxfornc.bsky.social, is running for Congress in North Carolina. He is a scientist, professor, and parent, perspectives that are especially important right now. I hope you will support his run for Congress. Find out more here: www.maddoxforcongress.com/about/

Nature Communications will publish ~10K papers in 2025 pubmed.ncbi.nlm.nih.gov?term=%22Natu... That's ~$70M in revenue, while many of the non-profit journals that used to occupy that slot in the journal hierarchy have seen a precipitous decline in submissions in the 15 years it's existed.

I'm floored by colleagues who are totally not interested in understanding the Nature Comms scourge of academic publishing and just throw their science and their money at these losers

C. elegans is a little animal with sexually dimorphic tails. Fitch lab does wonderful work on the evolution and transcriptional regulation of tail tip morphogenesis in nematodes.

New in #GENETICS: Using Chip-seq and mutant analysis, Fernandez et al. show the transcriptional control of the male tail tip morphogenesis during development by the master regulator of a male-specific morphogenesis gene DMD-3. buff.ly/EGahYv2

I didn't think I could admire Azim Surani more than I already did journals.biologists.com/dev/article/...

Hi fellow C. elegans scientists, I've made a few videos that may be of use for new trainees working in worm labs. Hoping to add more in the future, but figured I'd share this resource as is in case it's helpful :) www.youtube.com/@Workingwith...

For academic purposes, I generated 100 UMAPs from the same tabular raw data, I sorted them and the result looks too funny to not share it with you 😃 haesleinhuepf.github.io/BioImageAnal...

C. elegans is a real animal and we set out to understand how it comes to have its distinctive biogeography. Its ancestral center of diversity is in the higher elevation forests of Hawaii. Its closest relatives are spread across east Asia. Did they travel from Asia? [Preprint 🧵]

This is my reminder of what the American people need from her. 2/2

For who still thinks this can’t happen here… it’s already happening. www.theatlantic.com/science/arch...

The "reproducibility crisis" in science constantly makes headlines. Repro efforts are often limited. What if you could assess reproducibility of an entire field? That's what @brunolemaitre.bsky.social et al. have done. Fly immunity is highly replicable & offers lessons for #metascience A 🧵 1/n

Andrew Cuomo thinks its absurd for the city try to to own a grocery story while New York State owns three (!) ski resorts and Cuomo personally oversaw their operation, even heralding it in his state of the state address. Look it up if you don’t believe me.

Great ad. This guy is great. Don’t let anyone tell you otherwise. Don’t be deterred by racist scare tactics! This guy is great, as is Lander. Don’t rank Cuomo.

Springer-Nature launched a series of "Discover" journals that closely mimic MDPI titles -- sharing *identical* journal names, and likely similar business model. What is going on, and why researcher will - as always - fall for it? A 🧵 the-strain-on-scientific-publishing.github.io/website/post...

New from The Strain Team: 🎊 Springer Nature Discovers MDPI 🎊 Springer Nature has spawned a copycat journal series called "Discover" mimicking #MDPI journal titles and citation behaviours. We even made a browser game to prove it (see 🔗). Gross! 😀 1/n #ResearchIntegrity #SciPub #AcademicSky

CUNY and SUNY faculty, please sign this letter to the NY State Congressional Delegation protesting cuts to research funding (and all the other crap going on)! docs.google.com/forms/d/e/1F... Thank you for reposting!

At last night's mayoral forum cosponsored by Hell Gate and NY Focus at the Public Theater, @zohrankmamdani.bsky.social asked @bradlander.bsky.social a question that Lander was more than ready to answer: What he thought was the worst thing Andrew Cuomo did as governor.

The new Neil Halloran documentary on Smallpox has completely changed how I see the RFK Jr. version of the world. Neil (softly) argues that realizing that disease isn't the fault of the sick /or/ the fault of the Gods ushered in a new future where we felt the authority to care for each other.

What a horror show to have put that man in charge of anything. The documentary is very short and very good. You can watch it here: www.youtube.com/watch?v=ybVZ...

This was illuminating and useful… not at all surprised by my #1, but I made helpful discoveries elsewhere. (And no, I'm not telling.) FW: Find your own match, powered by @thecity.nyc and @gothamist.com: projects.thecity.nyc/meet-your-ma...

our latest work summary: cohesin is preferentially loaded at/near active enhancers and loop extrudes in both directions, forming loops that create the dna contacts that appear as the newly defined "fountains" in hic maps pubmed.ncbi.nlm.nih.gov/40210441/

Politicians, lawyers and journalists who left behind autocratic systems in Europe, Asia and Latin America see the Trump administration employing similar methods.

Love worms, molecular genetics, and big questions? We’re hiring a postdoc to build a CRISPRa toolkit to identify new aging mechanisms in C. elegans. Email or DM me to find out more. Please share & repost!

My lab at NYU is hiring a postdoc interested in RNA biology and local translation in neurons following axonal injury/neurodegenerative diseases!! Apply here: apply.interfolio.com/165681

The DNA in our cells is not naked but instead is compacted by being wrapped around nucleosomes assembled from histone proteins. In our current view, this produces the chromatin architecture that leaves some regions open for transcription while others are more compacted & transcriptionally silent 1/n

Again, pay attention to how it goes.

Bluetorial: Women, courage, and leadership What follows will include some generalizations based on population averages of what I have experienced over the course of my career. There are, of course, exceptions in every group who are substantially more to one extreme or the other.

Lots of people at the rally in New York! Josh Dubnau from Stony Brook gave the speech the moment demands: attacks on science funding are bad, but they’re downstream of fascism, and we need to fight the fascism even when we’re not the targets

A well-done story from a reporter in Türkiye. trt.global/world/articl... Thanks 1/3

"downsizes" is a weak way of saying "forced to cancel dozens of programs, which jeopardizes future STEM careers of talented undergrads" @science.org www.science.org/content/arti...

By accepting Trump’s anti-Black premise and regurgitating the narrative that equates anything Black as DEI, the NY Times has become part of the propaganda machine

It’s probably a good day to explain to your non-scientist socials that graduate students are not merely the next generation of academic science, they are an important component of the current scientific labor force. Feel free to mention that this is cut rate labor as well.

I hope that everyone in the private sector who depends on federal grants to train their researchers and staff, pay for their services and products, or benefits in any other way from federal funding will come out to #standupforscience!

ATTENTION BAJORAN WORKERS #STARTREK #SISKO197

DEI initiatives are still legal. Universities need to stand their ground. A Friday gift to your university's General Counsel Office - courtesy of an all star lineup of civil rights lawyers and scholars. You're going to want to read this.

To all people who value science as a source of truth, cures for diseases, and hope for our climate and future, here are 2 hard truths: 1) our current research ecosystem is already strained and very fragile; 2) If it gets broken it will take a generation or longer to repair. Here’s why: 1/n

A must read for any (systems) biologist! www.cell.com/cell-systems...

@altcdc.bsky.social if you are a CDC probationary employee who is losing your job today you can reach me on Signal. meredithwadman.13 Please help @science.org tell this story. Confidentiality guaranteed.

Application deadline is March 31. The symposium is June 5. This program is part of our ongoing effort to develop and maintain a diverse and inclusive community of scholars. We're not obeying in advance, and we're not obeying later either!

Late-stage PhD students: We want to bring you to NYU Biology to meet peers and make connections with potential postdoctoral mentors. Apply to be part of our Emerging Scholars Symposium!

Trainees who applied for an NIH diversity fellowship whose applications were withdrawn/not being reviewed, there's a NYTimes reporter who wants to talk, especially interested in applicants with disabilities. DM me & I'll put you in touch, will keep all contact confidential. Please amplify

It’s been a tough few weeks. My 10yo daughter was diagnosed with a very rare, aggressive cancer called interdigitating dendritic cell sarcoma (IDCS). I’m reaching out to identify clinicians/patients who have encountered pediatric IDCS or other (non-LCH) dendritic or histiocytic sarcomas cases.

1. Today the NIH director issued a new directive slashing overhead rates to 15%. I want to provide some context on what that means and why it matters. grants.nih.gov/grants/guide...

ATTENTION If you are someone who had an F31-Diversity (or similar) application submitted this cycle, please DM me here, contact me on signal (jeremymberg.78), or email me at [email protected]. I will keep all information confidential. 2/n

The CSR comm I'm on just pulled all Diversity F grants from the current review cycle. These apps are reviewed alongside (and by the same criteria) as all other F grants. So, instead of helping these trainees, they will actually be punished by having their grant reviews delayed at least 1 cycle !?!?