Very proud of our new paper! Great job @mweilert.bsky.social, our experimentalists and modeling collaborator Rosa Martinez-Corral. It was fun to see the story grow and get feedback from various experts. Thank you all!

It’s been fun figuring out why some degenerate motifs matter while others don’t. Turns out there’s a whole syntax behind it, relying on cooperativity!

Like regulatory genomics? Don’t miss this very fun meeting! May 7 is the deadline for early registration and abstract submission www.asbmb.org/meetings-eve...

🚨PRE-PRINT 🧪🧬🖥️👩‍🔬 Long-range massively parallel reporter assay reveals rules of distal enhancer-promoter interactions From Barak Cohen's lab at @washu.bsky.social Read the pre-print 👇 doi.org/10.1101/2025... Learn more about the research from the Cohen lab: bclab.wustl.edu

Our new preprint is out! Want to better visualize what your sequence-to-function profile learned? Here is PISA. It also comes in a new BPNet package, which can be used to train many genomics data sets, including MNase-seq data.

Very proud of two new preprints from the lab: 1) CREsted: to train sequence-to-function deep learning models on scATAC-seq atlases, and use them to decipher enhancer logic and design synthetic enhancers. This has been a wonderful lab-wide collaborative effort. www.biorxiv.org/content/10.1...

We're thrilled that Investigator @juliazeitlinger.bsky.social is co-chairing the 2025 @asbmb.bsky.social meeting in #KansasCity, which will delve into the core processes of #geneexpression from #developmental and evolutionary perspectives. Read more: bit.ly/41Czvqy

This a great interdisciplinary gene expression meeting, where everyone is welcome. Please consider attending and submitting your abstract: www.asbmb.org/meetings-eve...

Thermodynamic principles link in vitro transcription factor affinities to singlemolecule chromatin states in cells www.biorxiv.org/content/10.1...

5 minutes on this platform and it's already clear leaving Twitter was a great call, glad to see everyone <3