Sanjay Narayanaswamy
@sanjay-n.bsky.social
📤 214
📥 679
📝 15
Came for science. Staying for the memes. PhD student at
@ulrichtechnau.bsky.social
Lab, Uni Wien
pinned post!
Happy to be presenting our story on Nematostella self-organization :) tune in if you like to hear what organizes the organizer in cnidarian gastruloids!
www.biorxiv.org/cgi/content/...
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6 months ago
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Sanjay Narayanaswamy
Gesellschaft für Entwicklungsbiologie e.V.
12 days ago
That's it:
#GfE2026
#GfESEBDDSDB2026
is over. Thanks for the science, talks, posters, chairing, discussions, helpers in back & front. See you latest at
#GfE2028
for more
#DevBio
& oidsks for all the fish, plants, mice, worm, flies, frogs, squids, brown algae, human, -oids, whatnots and you.
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Sanjay Narayanaswamy
Tatiana Lebedeva
12 days ago
Honored and very grateful to receive the GfE PhD Award 2026! Many thanks to GfE for the recognition of our work! This would not have been possible without the guidance of my supervisor
@genikhovich.bsky.social
and the many amazing collaborators and colleagues who contributed along the way ❤️.#GfE2026
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Sanjay Narayanaswamy
Gesellschaft für Entwicklungsbiologie e.V.
13 days ago
The GfE PhD Award 2026 goes to Tatiana Lebedeva (
@tclebedeva.bsky.social
) for her outstanding contribution to developmental biology. She presents the topic of her thesis on the "Role of β-Catenin signaling in germ layer specification in Cnidaria".
#GfE2026
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Sanjay Narayanaswamy
Alex Eve
13 days ago
#gfe2026
@gfeev.bsky.social
PhD Award goes to Tatiana Lebedeva 🎉 for Tatiana's thesis investigating the role of β-catenin in specifying germ layers in one of my favourite organisms, the starlet sea anemone, Nematostella.
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Sanjay Narayanaswamy
Proceedings of the National Academy of Sciences
25 days ago
Opinion piece: Can space be democratized? India’s frugal #space innovation offers key lessons for #EmergingNations. In PNAS Front Matter:
https://ow.ly/QN1N50Yn1ps
#space
#EmergingNations
#ISRO
#India
#Chandrayaan3
#SpaceProgram
#NASA
#MAVENOrbiter
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Sanjay Narayanaswamy
Matt Gibson
27 days ago
New preprint from Ruohan Zhong on the architecture of the Nematostella nervous system, check it out!
www.biorxiv.org/content/10.6...
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https://www.biorxiv.org/content/10.64898/2026.01.28.701697v1
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Sanjay Narayanaswamy
Michael Sars Centre
about 2 months ago
New paper out in
@bmc.springernature.com
🤩👏 A routine 5-ethynyl uridine (EU) RNA labeling experiment in a sea anemone turned into detective work for
@malinkjosavik.bsky.social
,
@ktgarschall.bsky.social
&
@prhsteinmetz.bsky.social
🕵️♀️
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A widely used RNA assay labels the wrong molecules in several model organisms
After a routine experiment raised suspicions, Steinmetz group researchers joined forces with collaborators to highlight the limitations of a commonly used RNA labeling product.
https://www.uib.no/en/michaelsarscentre/181287/widely-used-rna-assay-labels-wrong-molecules-several-model-organisms
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Sanjay Narayanaswamy
Jakub Harnos lab
2 months ago
New Paper Alert! 1982: WNT discovered 1990s: NOTCH enters the stage 2000s: “Let’s study pathways separately.” 2025: “Actually, they talk to each other.” Welcome to the era of WNT-NOTCH crosstalk Great collaboration with Mašek lab (CZ) and G. Collu (US)
royalsocietypublishing.org/rsob/article...
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Decoding ‘Wntch’: the intertwined Wnt and Notch pathways in development and disease
Abstract. Multicellularity emerges from the ability of cells to undergo functional differentiation. One of the key mechanisms that enables this coordinatio
https://royalsocietypublishing.org/rsob/article/16/1/250282/479550/Decoding-Wntch-the-intertwined-Wnt-and-Notch
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Sanjay Narayanaswamy
Inés Fournon Berodia
3 months ago
Thrilled to share the preprint from my PhD! 🥳 Where I characterised epithelial cell extrusion in a sea anemone 🔗
www.biorxiv.org/content/10.6...
Big thanks to my supervisor
@prhsteinmetz.bsky.social
and coauthors
@noahbruderer.bsky.social
@lionlchristiaen.bsky.social
at🇳🇴
@msarscentre.bsky.social
⬇️🧵
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Sanjay Narayanaswamy
Andy Baxevanis
3 months ago
A new Hydractinia single-cell atlas from the Schnitzler lab: >47K cells from feeding polyps and stolon tissue that refines major somatic cell lineages and recovers a novel population of putative immune cells – a valuable resource for the cnidarian research community and beyond!
tinyurl.com/hsymSC
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An updated and spatially validated somatic single-cell atlas of Hydractinia symbiolongicarpus - BMC Genomics
Single-cell RNA sequencing (scRNA-seq) has revolutionized transcriptomic research, enabling the creation of detailed tissue, organ, and species-level atlases for model organisms. In Hydractinia, a cni...
https://tinyurl.com/hsymSC
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Sanjay Narayanaswamy
Paul Knabl
4 months ago
Congrats to Nadja and the
@tessmarraiblelabs.bsky.social
. Check out their cool new work (featuring a small sketch I made)!
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Sanjay Narayanaswamy
Tessmar-Raible Labs
4 months ago
Freshly out at
@natcomms.nature.com
! Our
@univie.ac.at
@awi.de
@viennabiocenter.bsky.social
@ercgrantees.bsky.social
research into neurogenic plasticity of adult worm brains, and similarities in stem cells supporting growth of camera-type eyes.
www.nature.com/articles/s41...
[1/7]
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This is so cool :)
add a skeleton here at some point
4 months ago
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Sanjay Narayanaswamy
Oded Rechavi
5 months ago
BIG ANNOUNCEMENT📣: I haven’t been this excited to be part of something new in 15 years… Thrilled to reveal the passion project I’ve been working on for the past year and a half!🙀🥳 (thread 👇)
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Sanjay Narayanaswamy
Nat Clarke
6 months ago
🚨 My lab is hiring at all levels! Interested in animal origins & evolutionary cell biology? I'm recruiting a postdoc, PhD students & a research assistant to study the molecular evolution of cell adhesion using marine invertebrates + comparative genomics. 🔗:
clarkelab.com/join/
Please repost!
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Sanjay Narayanaswamy
Kate Cavanaugh
6 months ago
See this? This = implanting mouse embryo. Usually this happens inside its mother and is invisible to us, but we can actually watch implantation ex vivo with the hope of understanding why implantation goes awry in embryos of older women. A 🧵...
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Sanjay Narayanaswamy
Arnau Sebé-Pedrós
6 months ago
Happy to share the Biodiversity Cell Atlas white paper, out today in
@nature.com
. We look at the possibilities, challenges, and potential impacts of molecularly mapping cells across the tree of life.
www.nature.com/articles/s41...
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reposted by
Sanjay Narayanaswamy
6 months ago
Just came back from a great meeting in Tutzing on the biology of basal Metazoa. Excellent talks, fantastic posters and very kind and vital community. Thanks also to our keynote speaker, Cassandra Extavour. She was the highlight of the meeting. Thanks everyone for contributing.
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Sanjay Narayanaswamy
Virtual Gastrulation Zoom Talks
6 months ago
We are excited to announce the first Western VGZT of Season 7! 🎉 🗓️ Thursday, October 2nd ⏰ 9:30 PDT / 12:30 EDT / 16:30 UTC / 17:30 BST / 18:30 CET Our speakers: 👉 Antonia Weberling (
@a-weberling.bsky.social
) 👉 Sanjay Narayanaswamy (
@sanjay-n.bsky.social
)
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Happy to be presenting our story on Nematostella self-organization :) tune in if you like to hear what organizes the organizer in cnidarian gastruloids!
www.biorxiv.org/cgi/content/...
add a skeleton here at some point
6 months ago
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13
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reposted by
Sanjay Narayanaswamy
Development
6 months ago
Hydra body axis balance: a fight between two transcription factors This Research Highlight showcases the work from Jaroslav Ferenc, Marylène Bonvin, Panagiotis Papasaikas, Jacqueline Ferralli, Clara Nuninger and Charisios D. Tsiairis:
journals.biologists.com/dev/article/...
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Sanjay Narayanaswamy
6 months ago
We knew that cnidarians have stunning regenerative capacities. But the molecular and cellular mechanisms underlying the self-organization of gastruloids of Nematostella surprised us. A story of cell sorting and Notch signaling. Please check out the work of Sanjay's PhD work:
doi.org/10.1101/2025...
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🚨 Happy to share my PhD work! We set out to find what organizes the organizer in Nematostella gastruloids. While we knew Wnt1/3+ cells confer axial polarity, we identify the role of Notch signaling as partner in crime in polarising these organizers. How does it do it?
www.biorxiv.org/cgi/content/...
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6 months ago
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Sanjay Narayanaswamy
7 months ago
Finally, the excellent postdoc work of Emmanuel Haillot is out, where he dissected the integration of Wnt, MAPK and Notch signaling in defining mesoderm and endoderm identities in the diploblast Nematostella. Strikingly similar to sea urchins.
www.nature.com/articles/s41...
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Sanjay Narayanaswamy
8 months ago
Great opportunity! The Uni Vienna has launched a call (APART) for 4-funding for outstanding postdocs from a US institution. The host lab has to nominate by 1 August a candidate for further selection. Anyone interested in our work please contact me by email with CV/motivation letter. Hurry up!
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Nematostella butt valve!
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10 months ago
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Sanjay Narayanaswamy
Alfonso Martinez Arias
10 months ago
In which we discuss the homologies between amphibian and mammalian organizers from the perspective of
#gastruloids
with special relevance to recently described A and C gastruloids as containing Spemann/Mangold and Trunk/Tail organizers
www.sciencedirect.com/science/arti...
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We review self-organisation of organizers through the lens of Cnidarians (primarily Hydra and Nematostella) and propose an integrative Mechanochemical view for the same. Happy to be part of the 100 year Mangold-Spemann special edition
@cellsdev.bsky.social
@ulrichtechnau.bsky.social
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11 months ago
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Sanjay Narayanaswamy
11 months ago
About 100 years the Mangold-Spemann organizer was published and this has been one of the most fruitful and inspiring concepts in Developmental Biology. But how can organizers self-organize? In this review we summarize the knowledge how cnidarians do that:
doi.org/10.1016/j.cd...
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Redirecting
https://doi.org/10.1016/j.cdev.2025.204024
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reposted by
Sanjay Narayanaswamy
Ste Tavano
about 1 year ago
Here our model of how LME animal migration ends. I am happy to see this work out! As for cell migration in vivo, the path of this journey hasn’t always been straightforward. It is the closing of a chapter, and I look forward to what the future will bring.
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Happy to have presented our evolving story at
#DevStem2025
. Exciting stuff on the way :)
add a skeleton here at some point
12 months ago
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Sanjay Narayanaswamy
Tessmar-Raible Labs
12 months ago
Kick-off of the late afternoon session at the
#DevStem2025
meeting. Sanjay Narayanaswamy
@sanjay-n.bsky.social
from
@ulrichtechnau.bsky.social
lab discusses germ layer biology in
#Nematostella
, exploring a powerful gastruloid system. For a primer on gastruloids, see
doi.org/10.1016/j.cd...
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Sanjay Narayanaswamy
Kristina Stapornwongkul
12 months ago
We’re looking for PhD students to join the lab! 🧫🧑🔬 Curious about how metabolic processes shape patterning and morphogenesis? Enthusiastic about stem cell models for human development? - Then apply through the VBC PhD program!
training.vbc.ac.at/phd-program/
‼️Deadline: April 15‼️
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PhD Program
Empowering Curious Researchers at the Vienna BioCenter PhD Program Are you a curious and motivated student looking to launch a successful scientific career? Look no further than the Vienna BioCenter P...
https://training.vbc.ac.at/phd-program/
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Sanjay Narayanaswamy
the Node
12 months ago
Unexpected role of β-catenin signaling in germ layer specification In this 'Show and tell' post,
@genikhovich.bsky.social
and
@tclebedeva.bsky.social
tell us about their video of a GFP-β-catenin knock-in Nematostella embryo from their latest paper: 🎥
thenode.biologists.com/unexpected-r...
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Beautiful!
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12 months ago
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Arguably the most significant step forward in discovery dissemination.
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about 1 year ago
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Sanjay Narayanaswamy
Biology Open
about 1 year ago
We are excited to be launching the next phase of our Fast & Fair peer review initiative: offering high-quality peer review within 7 working days.
#fastandfairpeerreview
Read the Editorial by EiC Daniel Gorelick
@danielgorelick.bsky.social
at:
bit.ly/4kYD1mL
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Sanjay Narayanaswamy
Eszter Posfai
about 1 year ago
How many cells do you need to establish PCP? The magic number is 3! Beautiful work by Lena Basta in Danelle Devenport's lab. Happy to have contributed.
www.science.org/doi/10.1126/...
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Epithelial polarization by the planar cell polarity complex is exclusively non–cell autonomous
For cells to polarize collectively along a tissue plane, asymmetrically localized planar cell polarity (PCP) complexes must form intercellular contacts between neighboring cells. Yet, it is unknown wh...
https://www.science.org/doi/10.1126/science.ads5704?url_ver=Z39.88-2003&rfr_id=ori:rid:crossref.org&rfr_dat=cr_pub%20%200pubmed
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Had an amazing time presenting some of our work with
#Nematostella
at the
#gastruloids
meeting in beautiful Barcelona. Lots of science and cool breeze!
about 1 year ago
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Sanjay Narayanaswamy
Richard Behringer
about 1 year ago
Developmental biology research leads to fundamental discoveries for biomedical research. Apoptosis. Ellis & Hovitz, 1986. PMID: 3955651. Worm image by Tokiko Furuta (Arur Lab)
@socdevbio.bsky.social
9/12
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Sanjay Narayanaswamy
Development
about 1 year ago
In preprints: the ins and outs of Cnidaria germ layers Lucas Leclère and Chiara Sinigaglia
@chisinig.bsky.social
(
@cnidevo.bsky.social
@biom-banyuls.bsky.social
) discuss 3 recent
#preprints
about the mechanisms that govern germ layer formation in Nematostella vectensis:
doi.org/10.1242/dev....
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Sanjay Narayanaswamy
about 1 year ago
Ambitious students interested in our attractive joint Master program "Evolutionary Genomics and Systems Biology" at the University of Vienna and the VetMed Uni should apply:
studieren.univie.ac.at/en/degree-pr...
Deadline April 7! The Bachelor only needs to be completed by September. Spread the word
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Evolutionary Genomics and Systems Biology (Master)
Evolutionary Genomics and Systems Biology (Master)
https://studieren.univie.ac.at/en/degree-programmes/master-programmes/evolutionary-genomics-and-systems-biology-master/
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*hearing crickets*
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about 1 year ago
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Sanjay Narayanaswamy
Yehu Moran
about 1 year ago
1/3 Our paper about miRNA target complementarity in Cnidaria is finally published in
@emboreports.bsky.social
This work was led by the talented Yael Admoni with help from Arie and Rubi in collaboration with the labs of
@thecocodium.bsky.social
and Michal Rabani
www.embopress.org/doi/full/10....
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miRNA-target complementarity in cnidarians resembles its counterpart in plants | EMBO reports
imageimagemiRNAs in plants and cnidarian animals operate similarly by binding their targets with nearly-full complementarity, in contrast to miRNAs in bilaterian animals that bind via a short seed-mat...
https://www.embopress.org/doi/full/10.1038/s44319-024-00350-z
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Sanjay Narayanaswamy
Uri Frank
about 1 year ago
#Hydractinia
takes regeneration to the extreme¬in a new preprint, Curantz et al. show that dissociated, reaggregated cells can form a new individual. We also show how they do it and which cells types actually contribute to the new individual (tip: not many of them).
tinyurl.com/mr2s9zyf
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Sanjay Narayanaswamy
Richard Sever
over 1 year ago
Many academics point to bioRxiv as “the one thing improving science publishing”. If so, the one thing you all can do is persuade colleagues to submit and make this a norm. 1/2
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Is it just me or is
@biorxivpreprint.bsky.social
down somehow? It either cannot load papers or the ones that load have the right titles but abstracts and full text of other papers instead...
over 1 year ago
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Sanjay Narayanaswamy
Cnidarian developmental mechanisms group
over 1 year ago
That was another nice find -thanks John. We love Metchnikoff too -especially for his substantial contribution to invertebrate embryology, including of course this !
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Sanjay Narayanaswamy
Watanabe Lab @JHU
over 1 year ago
Excited to share our latest findings, now published @NatureNeuro
www.nature.com/articles/s41...
We found unmyelinated axons exhibit pearls-on-a-string morphology's due to their membrane mechanical properties. Threads will follow!
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Sanjay Narayanaswamy
God
over 1 year ago
Dear everyone, Sorry for everything.
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