Pre-print alert 📰 🚨I’m very grateful and excited to share our new study : "Defective B cell tolerance in SLE lymph nodes underpins VH4-34 "clonal damnation" and PD-1+TOX+ autoreactive B cells expansion". doi: doi.org/10.64898/202... lnkd.in/eJwMTUEt

'In short, human genetics has become an evolutionary science in a way that can’t be undone. You cannot meaningfully study how humans function or differ from one another without understanding how evolution has shaped us.' www.johnhawks.net/p/what-i-tol...

Looking forward to #AAI2025 science and connections! #AAI2025 #ImmunoSky

#Medsky🧪 #pedsky #immunosky #IDsky #publichealth Children under the age of five have an average incidence of 4 to 6 viral respiratory infections per year, which increases the risk of developing acute bacterial sinusitis or mastoiditis. www.thelancet.com/journals/lan... @thelancetinfdis.bsky.social

Delighted our study (7+ years in the making) is out today in Nature. In a nutshell, 48 hours of antibiotics in week 1 led to impaired vaccine responses up to 15 months later in infants. We show (in-vivo) a probiotic can fix it #microbiome #science #immunology www.nature.com/articles/s41...

Letting mice experience the "wild" alters their immune system, especially their B-cells! Also, we talk to an organizer of the Atlanta #standupforscience2025 about his experience 🧪 www.youtube.com/watch?v=7Hgo...

'The scale of disruption to science funding in the USA is unprecedented. At the NIH, study sections, funding councils and project meetings have been cancelled. Without these, new grants cannot be funded or renewed. Fellowship programs have been cancelled.' journals.biologists.com/dev/article/...

So, not to diminish that this is a good thing but... we still don't know who they'll nominate in his place.

‘One last thing’: Trudeau posts message to Canadians on final day as prime minister #Canada #cdnpoli #ThankYouPMTrudeau 🍁💪🏻 www.ctvnews.ca/politics/art...

I refuse to accept a post-truth reality where knowledge and humanity no longer matter. Stand up for Science!! #standupforscience

Yeah, this 100%

Cool paper from the Davis lab using human tonsil organoids to study CD4 and CD8 Tregs. Even though subjects with autoimmunity were excluded, organoids derived from female donors had higher autoreactivity, providing an ex vivo system to study sex differences in response to self antigens. #ImmunoSky 🧪

Darkest of times... #ImmunoSky

We have to fight now for research that we know benefits all of humanity, we have to stand up for our colleagues at the NIH, we can’t lie down and take it, we stand against this madness #standupforscience2025

@katherinejwu.com getting straight to the ❤️ of the crisis. This current attack on science must be stopped to protect all Americans.

My weekend with immunologists devising new strategies to treat cancer, allergy, Alzheimer’s, autoimmunity and infection. The WH has just paused peer-reviewed NIH funding that pays for these studies. If you care about human life, write your representatives. Demand that NIH funding is restored asap.

I got interviewed by @nature.com 🙃🧪 www.nature.com/articles/d41...

Talk to your department chairs and research offices! 🧪

Thank you @emoryuniversity.bsky.social for highlighting our recent study in NI! @natureportfolio.bsky.social (we did not make it to cover selection, but I love it anyway) #immunoSky Links url:https://news.emory.edu/stories/2025/01/er_lupus_and_mrna_15_01_2025/story.html rdcu.be/dZWI9 rdcu.be/d4332

Congrats @kevbonham.bsky.social! Great news! They are lucky to have you! Looking forward for exciting collaborations :) #immunoSky

New! @jenncoughlan.bsky.social kindly shared their MIRA NIH award with our github repo. If you have a successful grant app you're willing to share, please contribute! github.com/RILAB/statem...

Fantastic News & Views article Nature Portfolio by @michelalocci.bsky.social & @sapostolidis.bsky.social, highlighting our recent study on mRNA vaccines and SLE, its findings, and the key questions to address next! rdcu.be/d4332 #immunosky #SLE #mRNA #Bcells 🦠 👩‍🔬 💉

@johnmlindner.bsky.social It was a pleasure hosting you at #Emory! Thanks for sharing your remarkable insights into the T-Finder discovery pipeline. Excited for the collaborations ahead in T cells, B cells, and to more adventures in Atlanta’s diners with you and @eliverghosn.bsky.social #immunosky

Dr Kuchroo discussing the discovery and properties of TIM-3 and Tcf1 on T cells and beyond! @emoryuniversity.bsky.social #treg #dc #tim-3 #ImmunoSky

Totally agree! Fantastic scientist and human being!

Like a photographer choosing between quick snapshots or careful portraits, our immune system balances fast action and precise antibody creation. @profshanecrotty @katyely.bsky.social @johnmlindner.bsky.social @cellpress.bsky.social @emoryuniversity.bsky.social t.co/E2WUBinqCd #ImmunoSky 🧪

✨ Ever wondered why B cells are so fond of IL-2? Wonder no more! Our study is now published in Immunity @cellpress.bsky.social 🔍📑 A truly perfect Thanksgiving gift! 🧑‍🔬💉🔬https://authors.elsevier.com/c/1kAq43qNrUxuTR

Hello BlueSky! 🌟 I am excited to be here and finally chat immunology, systems biology, and vaccines again. 🧪💡 Also, we’re growing our team in beautiful Tübingen (thanks to @ERC_Research) and looking for talent in #AI or #scRNAseq. There is still time to apply! 🚀 www.nature.com/naturecareer...

As part of my role as Head of Research for US-based BioMed X teams: Alicia Cutler's Team CHM (based in New Haven, CT) is #recruiting an #immunology expert (postdoctoral fellow) to study the role of #inflammation in #vasculature using unique, complex, 3-D models: career.bio.mx/call/2024-NH...

To be fair, the natural variety is not doing great on this front either. "Lack of internal deliberation abilities — thinking, in other words — has long been considered one of the main weaknesses of artificial intelligence." Yoshua Bengio on the FT www.ft.com/content/8946...

Are you an Immcantation.org user or interested in B cell repertoire analysis? Register now for the 2025 Immcantation Users Group Meeting! The meeting will feature talks from users showcasing how they use Immcantation in their research. Info and registration at: immcantation.github.io/users-meetin...

Such a fantastic study from @petterbrodin.bsky.social and team with lots of insights and implications for gender-bias diseases and overall innovative medical personalized approaches. Congrats!

How to write a perfect Keystone Abstract: Start with -real fireplace -caponata (so good) and calamari (so fried) -did you say wine? The end. #Keystone #Bcell #Montecarlo

I learned some stuff about Bluesky I did not know by reading this. Maybe worth passing it on to others so we can all start getting the full benefit of the 🦋.

This worked for me!

Want to make beautiful scientific figures? Easy! The NIH released a library of 2000+ free scientific illustrations called *BioArt*. Check it out! bioart.niaid.nih.gov #AcademicSky #PsychSciSky 🧠🟦 🧪

BlueSky: A Guide for Scientists by @jacoates.bsky.social #AcademicSky #EduSky 🧪

We've already seen remarkable results for lupus and other autoimmune diseases with CD19 B cell depletion therapy. Now add IgG4 related disease (which has no treatment) in a new randomized trial nejm.org/doi/full/10....

Great study from the Ghosn lab! ! Thread below from @eliverghosn.bsky.social

Interested in working as a scientific editor? Apply to join our team in Heidelberg working for Life Science Alliance (www.life-science-alliance.org). Applications close November 15th! Apply: www.jobs.ac.uk/job/DKE564/s...

Our study just out! "Disease-associated B cells and immune endotypes shape adaptive immune responses to SARS-CoV-2 mRNA vaccination in human SLE". 🔗 * rdcu.be/dZWI9 * lnkd.in/desv-ZrV #SLE | #Autoimmunity | #mRNAvaccines | Disease-associated #Bcells shape anti-vaccine immunity in SLE. 👩‍🔬 💉💉💉 🦠