🎉 Big congrats to Tas Rookes for passing her PhD viva with flying colours! 🧠 Thesis: Improving engagement in health promotion for older adults with mild cognitive impairment 👏 Supervised by Professor Kate Walters, Louise Marston, Rachael Frost, Megan Armstrong & Yolanda Barrado-Martín

We're excited to share our latest work on estimands in clinical trials! 📄 Estimating treatment effects in trials with outcome data truncated by death: A case study on aligning estimators with estimands. 🔗 Read the full paper: journals.sagepub.com/doi/10.1177/...

Apply to work with me and a great team at @uclpsychiatry.bsky.social to do some exciting research using electronic health records! The position is funded for 19 months in the first instance and you’ll be joining a fascinating NIHR project: www.ucl.ac.uk/work-at-ucl/...

Evidence for health promotion interventions to improve cognitive and physical functioning outcomes in older adults with MCI: A state-of-the-art review www.sciencedirect.com/science/arti... @ucl-caps.bsky.social @ucl-primarycare.bsky.social @drmegs.bsky.social @tasminrookes.bsky.social

📢 New Publication Alert Congratulations to @Roganie Govender and the entire team on their latest publication! A fantastic achievement! @ucl-primarycare.bsky.social bmjopen.bmj.com/content/15/9...

Every data point tells a story. Statisticians ensure those stories are heard—spotting safety concerns, reducing bias, and ensuring ethical outcomes in clinical trials. 🔗 ukcrc-ctu.org.uk #Statistics #UKCTUNetwork #WorldPatientSafetyDay2025

📢 New dataset drop! The BRHS @ucl-brhs.bsky.social is now available via @ukdataservice.bsky.social 🎉 🔗 ukdataservice.ac.uk 7,735 men tracked over 50 years = goldmine for research on heart health, ageing & behaviour. Prof. Wannamethee: “Unparalleled insights into ageing & heart health.”

📌 The SPIRIT 2025 statement updates the guidelines for randomized trial protocols to enhance their completeness, transparency, and consistency, benefiting stakeholders involved in clinical research. ja.ma/4fzMVZS

Outcomes of specialist physiotherapy for functional motor disorder: the Physio4FMD RCT NIHR report out today www.journalslibrary.nihr.ac.uk/hta/MKAC9495 @nihr.bsky.social @ucl-primarycare.bsky.social @gnielsenphysio.bsky.social @jonstoneneuro.bsky.social

Methylphenidate versus placebo for fatigue in patients with advanced cancer: the MePFAC randomised controlled trial @nihr.bsky.social report out today. @ucl-primarycare.bsky.social www.journalslibrary.nihr.ac.uk/hta/GJPS6321

Want to help shape national dementia prevention strategies? We're looking for a Research Assistant on the PRACTICAL study ▶️ www.ucl.ac.uk/work-at-ucl/... Closing date: 13 Jul 2025 @ucl-primarycare.bsky.social

🎉 Huge congratulations to our PhD candidate, Dennis Emaralino, for successfully passing his PhD upgrade last week! His project, Anxiety, Depression, and Mental Wellbeing Among Young Adults in the Philippines. Very well done! 👏

We're excited to advertise a permanent role as a Clinical Lecturer in Primary Care (0.6FTE) in our Institute for a GP holding a PhD or equivalent qualification who would like to develop a career as an academic in research and education. Click here for more details: www.ucl.ac.uk/work-at-ucl/...

What a great PhD Research day we had at the UCL IEHC! Poster presentations and 3min thesis completion! Well done everyone 👏👏👏👏

The CONSORT and SPIRIT statements for randomized trials have been updated for 2025 and published in JAMA, with a new focus on open science principles and guidance on trial registration, data access, and conflict of interest reporting. ➡ CONSORT 2025: ja.ma/3Yyu0Hh ➡ SPIRIT 2025: ja.ma/3YjFfn8

NEW PAPER: Updated CONSORT-2025 for reporting randomised trials is now available in the @bmj.com @jama.com , @thelancet.bsky.social, @plos.org and @naturemedicine.bsky.social —> www.bmj.com/content/389/... #openscience #transparency #medsky #statssky #episky

The association between relapse and the outcome of schizophrenia and recurrent psychotic disorders doi.org/10.1192/bjp.... @joannamoncrieff.bsky.social @soniajohnson1.bsky.social @ucl-primarycare.bsky.social @uclpsychiatry.bsky.social

Estimands define the research question in #ClinicalTrials to help stakeholders understand and interpret trial results and make better decisions about treatments. Our latest video explores the importance of estimands in the context of a mental health trial. Watch now ▶️👇 buff.ly/xiz3mU6 #StatsSky

researchinvolvement.biomedcentral.com/articles/10.... PETAL PPIE involvement in developing the intervention. @proflikahass.bsky.social @ucl-primarycare.bsky.social @uclpsychiatry.bsky.social

Open Access UCL Research: Exploring the effect of COVID-19 restrictions on the Social Functioning Scale in a clinical trial of Antipsychotic Reduction: using multiple imputation to target a hypothetical estimand discovery.ucl.ac.uk/id/eprint/10...

A personalised health intervention to maintain independence in older people with mild frailty: a process evaluation within the HomeHealth RCT doi.org/10.3310/MBCV... @ucl-primarycare.bsky.social @uclpsychiatry.bsky.social @ucl-caps.bsky.social

The economic evaluation of the Physio4FMD trial was finally published today! www.neurology.org/doi/10.1212/... @jonstoneneuro.bsky.social

@suziecro.bsky.social Introducing what is sure to be an exciting day ahead at the 2nd Contemporary Clinical Trials Methodology Meeting! #cctmm25

Cost Utility of Specialist Physiotherapy for Functional Motor Disorder (Physio4FMD) www.neurology.org/doi/10.1212/... @ucl-primarycare.bsky.social

In-patient service use before and after a mental health in-patient rehabilitation admission in @bjpsych.bsky.social Open doi.org/10.1192/bjo.... @ucl-primarycare.bsky.social @uclpsychiatry.bsky.social Part of Christian Dalton-Locke's PhD.

Exploring the effect of COVID-19 restrictions on the social functioning scale in a clinical trial of antipsychotic reduction: using multiple imputation to target a hypothetical estimand is out in @jclinepi.bsky.social www.sciencedirect.com/science/arti... 1/n

📢New publication: Exploring the effect of COVID19 on the Social Functioning Scale in a Antipsychotic Reduction trial using multiple imputation to target a hypothetical estimand by @proflouisemarston.bsky.social @suziecro.bsky.social @vcornelius.bsky.social et al www.sciencedirect.com/science/arti...

We’re waiving the article-processing charge (APC) for articles submitted before Aug 3, 2025. Read our commitment to publishing excellence, reach and impact, meet our editorial team, and take advantage of this introductory offer ➡️ bit.ly/4jMtT45 #medsky #familymedicinesky #internalmedicinesky

Quetiapine may pip lithium to the augmentation post in 'treatment resistant depression': results from the LQD study buff.ly/Y7jCajZ #LQDstudy #Quetiapine #Lithium #Depression #RCT 🧵 THREAD

Exploring the effect of COVID-19 restrictions on the Social Functioning Scale in a clinical trial of Antipsychotic Reduction: using multiple imputation to target a hypothetical estimand - Journal of Clinical Epidemiology www.jclinepi.com/article/S089...

New publication led by @proflouisemarston.bsky.social using multiple imputation to target a hypothetical estimand in a pandemic restriction-free world for a trial in schizophrenia - demonstrating the potential impact of the pandemic on the trial results

researchinvolvement.biomedcentral.com/articles/10.... PETAL PPIE involvement in developing the intervention. @proflikahass.bsky.social @ucl-primarycare.bsky.social @uclpsychiatry.bsky.social

Welcome Sonya!

Cost-Utility Analysis of Antipsychotic Reduction and Discontinuation in Patients With Long-Term Schizophrenia and Psychosis in English Mental Health Trusts: The RADAR Study www.valueinhealthjournal.com/article/S109... @ucl-primarycare.bsky.social @uclpsychiatry.bsky.social

Mediation of the association between education and dementia by occupational complexity, income, health behaviours and health outcomes @ucl-primarycare.bsky.social @uclpsychiatry.bsky.social

A new service aimed at supporting older people who are starting to become frail could reduce emergency hospital admissions by more than a third and save the NHS money, finds a new study led by Professor Kate Walters @ucliehc.bsky.social @uclpophealthsci.bsky.social www.ucl.ac.uk/news/2025/fe...

Congratulations to Professor Kate Walters and team on their latest publication! 📢 HomeHealth is highly likely to be cost-effective due to its impact on reducing unplanned hospital admissions. 👏👏https://sciencedirect.com/science/article/pii/S266675682400196X

Come and work with me as a statistician at Priment Clinical Trials Unit @ucl-primarycare.bsky.social @ucl.ac.uk. Suitable for people about to finish their MSc in Medical Statistics or similar. www.ucl.ac.uk/work-at-ucl/... #statistics #statsky #statsjobs

Which factors predict outcome from specialist physiotherapy for functional motor disorder? Prognostic modelling of the Physio4FMD intervention @ucl-primarycare.bsky.social

An investigation into the critical ingredients of intensive support teams for adults with intellectual disabilities who display challenging behaviour www.cambridge.org/core/journal... @proflikahass.bsky.social @ucl-primarycare.bsky.social @uclpsychiatry.bsky.social

Understanding how older people with mild frailty engage with behaviour change to support their independence: a qualitative study part of HomeHealth study. bmjopen.bmj.com/content/15/1... @ucl-primarycare.bsky.social

Do you work in #ClinicalTrials? Using the estimands framework can ensure your study answers the most relevant research question. In this podcast episode, @brennankahan.bsky.social discusses his work on estimands. 🎧Listen to short clip below & tune in to the episode👉 https://buff.ly/3PtETFq

@ucl-primarycare.bsky.social @uclpsychiatry.bsky.social @proflikahass.bsky.social

Development and modelling study of an evidence-based manualised intervention: PErsonalised Treatment packages for Adults with Learning disabilities who display aggressive challenging behaviour in community settings (PETAL) in @nihr.bsky.social Open Research openresearch.nihr.ac.uk/articles/5-1...

Are you excited about #research ? Do you want to support researchers to design excellent research. Looking for a research fellow to work with our amazing team at the NIHR Research Support Service @ucl-primarycare.bsky.social @ucl.ac.uk . Deadline 26th Jan. www.jobs.ac.uk/job/DLF313/r...

New #datamind paper: physical health screening in people with severe mental illness in the UK is insufficient. Until it improves, it seems hard to see how we will move the needle on premature mortality in this population

Announcing our #ESRC co-funded #PhD studentship on #suicide risk in the #construction industry @uclpsychiatry.bsky.social & @uclofficial.bsky.social Bartlett School of Sustainable Construction. Project outline here: ubel-dtp.ac.uk/co-funded-st... Apply here by 3/3/25 ubel-dtp.ac.uk/co-funded-st...

Has anyone explained the estimands they are going to use in a trial to a trial management group which includes service users, carers and other lay members?

New CONSORT extension for cluster-crossover trials published in @bmj.com www.bmj.com/content/388/...

Estimating undiagnosed dementia in England using capture recapture techniques doi.org/10.1186/s128... @ucl-primarycare.bsky.social