Wishing a very Happy Christmas to those who are celebrating!

We're wishing a very happy holiday season to all of our staff, collaborators, research participants, and social media followers! 🎄❄️🎁 We will be closed until Monday, 12 January, meaning our social media channels will not be monitored during this time. See you in the new year!

🎉 Big news! The MRC Centre for Clinical Research Efficiency (CoRE) is here. By accelerating the testing of new medicines, the MRC CoRE will help bring better treatments to patients sooner. 🔗 Learn more: www.mrcctu.ucl.ac.uk/news/news-st...

Let’s brighten up your Wednesday with another #ProudestOf moment from our brilliant colleagues at the Unit. This week, we are celebrating Lindsey Masters (@lkmasters.bsky.social), Head of Data Management Systems. We asked Lindsey what she was #ProudestOf in her work at the Unit 👇

🎁 Struggling with gift ideas for the upcoming holidays? Check out the festive gift guide from UCL’s start-up community with gifts created by UCL entrepreneurs. Buy your sustainable gift now! 👇

Happy Hannukkah to everyone celebrating!

🆕 Exciting new insights on how aspirin prevents cancer! A study from a new collaboration led by our researchers suggests that the anti-cancer effects of aspirin are mediated through suppression of platelet activation. 🔗 Read more about it: www.mrcctu.ucl.ac.uk/news/news-st...

Wednesdays are our #ProudestOf days at the Unit! This week, we are spotlighting Hanif Esmail, Professor of Infectious Diseases. We asked Hanif what he was #ProudestOf in his work at the Unit 👇

🎓 Considering a PhD in clinical trial #methodology? We have 6 PhD opportunities on innovative trial designs funded by the MRC Centre of Research Excellence in Clinical Trial Innovation. Check the 🧵below for specific PhD projects. 🔗 More info & how to apply: www.findaphd.com/phds/institu...

🆕New publication alert! Our latest systematic review of trials using Health Systems Data (HSD) shows that, although reporting has improved over time, it still falls short of CONSORT-ROUTINE guidelines. It includes 3 key recommendations 👇

Wednesday is our #ProudestOf day at the Unit! This week, we are featuring Charlotte Hartley, former Science Communications Officer at the Unit. We asked Charlotte what she was #ProudestOf during her time with us 👇

We drive global research to improve HIV care for the next generation. On #WorldAIDSDay, we share a thread highlighting our latest #ClinicalTrials that are transforming treatment for children and young people living with #HIV, helping them lead healthier, happier lives. 🧵

#ProstateCancer is the most common cancer in UK men. This #Movember, learn how our PROMIS study helped improve prostate cancer diagnosis, sparing thousands of men unnecessary biopsies. This was part of our 25 at 25 anniversary series from last year. Read more: www.mrcctu.ucl.ac.uk/news/news-st...

Feeling that Wednesday pride? We sure are! Check out our latest #ProudestOf moment from Peter Godolphin. He is a Senior Research Fellow working on meta-analysis #methodology. Here’s what Peter is #ProudestOf from his work at the Unit 👇

We are recruiting members of the public to help shape research on what it’s like to be pregnant, breastfeeding, or caring for a baby during an infection outbreak, like COVID. Read more about the project, who we are looking for, and how to apply here www.coproductioncollective.co.uk/news/help-sh...

📰 Excited to see our NeoSep1 trial in @theguardian.com today! NeoSep1 aims to find new antibiotic combinations for newborns with sepsis using our novel PRACTical design. 🔗 Read the full article here: www.theguardian.com/global-devel...

📝New guidance on data retention and re-use! We’re proud to have contributed to this resource alongside leading experts in the field. This guidance helps ensure responsible data management, compliance, and opportunities for data re-use, supporting transparency and research integrity across trials.

This week is World Antimicrobial Resistance Awareness Week #WAAW2025, a time to raise awareness & encourage action to reduce the #AMR crisis. We are fighting the rise of AMR through our #ClinicalTrials. Find out how our current research is making a difference in this thread 🧵

📈 New results from the SURE trial at #UnionConf SURE showed that, for children living with TB meningitis, a short, intensive treatment is not as good as the standard treatment in preventing death or severe disability. Adding high-dose aspirin also showed no benefit. 🔗 Read more:

It’s Wednesday, time to share what we’re #ProudestOf! Today, we celebrate Elena Frangou, one of our Senior Research Fellows and one of the statisticians in the RAMPART #ClinicalTrial. We asked Elena what she’s #ProudestOf in her work at the Unit 👇

📝 New guidance on improving the use of inverse probability of censoring weighting (IPCW) method in #ClinicalTrials. The paper explains how to apply IPCW effectively and how to stabilise IPCW weights to improve precision, without overlooking potential bias. 🔗 Read more about it:

#UnionConf2025 starts tomorrow! Our researchers and collaborators will showcase their latest #tuberculosis #TB research, including new findings from the SURE trial in TB meningitis in children. Check out our schedule of presentations. 🔗 www.mrcctu.ucl.ac.uk/news/news-st...

#ProstateCancer is the most common cancer among men in the UK. This #Movember, discover how our PROMIS study helped improve prostate cancer diagnosis, sparing thousands of men unnecessary biopsies. 📽️ More in this short video from our 25 at 25 anniversary series: www.youtube.com/watch?v=CcP3...

Wednesday’s here, and so is our latest #ProudestOf moment! This week, we’re celebrating Sharon Love, Associate Professor of Clinical Trial Conduct, who leads the methodology conduct work at the Unit. We asked Sharon what she’s #ProudestOf in her work at the Unit 👇

📺 Catch this short film on the ARCHERY study by LSHTM (@lshtm.bsky.social), where Dr. Ajay Aggarwal explores how AI could improve access to radiotherapy. A powerful look at tech-driven solutions to global cancer care challenges. 🔗 www.youtube.com/watch?v=lTox... #Radiotherapy #GlobalHealth

Wednesday already? Let’s celebrate another #ProudestOf moment from our brilliant team at the Unit! This week, we’re spotlighting Ilaria Motta, one of our passionate Principal Clinical Research Fellows working on tuberculosis #TB. We asked Ilaria what she’s #ProudestOf in her work at the Unit👇

Nominations for the Brighter Future Award (BFA) are still open! This international award, organised by Penta Foundation (@pentafoundation.bsky.social), celebrates individuals making a meaningful impact in maternal and child health. ⏳ New deadline: 11 Nov 🔗 Nominate your hero: penta-id.org/bfa/

Dr Sophie Merrick (@drsophiemerrick.bsky.social) presented at #ESMO25 results from her qualitative study within the RAMPART #ClinicalTrial. Her research highlights how immunotherapy impacts the lives of kidney cancer patients, an essential view in cancer care. 🔗 View the poster: buff.ly/fPtvyZ2

HRB-TMRN WEBINAR, with @mrcnihrtmrp.bsky.social - Prof. Max Parmar, Director of @mrcctu.bsky.social & UCL Institute of Clinical Trials, discusses 'Improving Health Faster: A more Strategic Approach to Randomised Trials & Meta-Analysis' on 20Nov@1pm(UTC): universityofgalway-ie.zoom.us/webinar/regi...

It’s Wednesday, which means it’s time to celebrate another #ProudestOf moment from our amazing team at the Unit! This week, we spotlight Tra My Pham, one of our dedicated senior Research Fellows working in analysis methodology. We asked Tra what she’s #ProudestOf in her work at the Unit 👇

We're excited to share our latest work on estimands in clinical trials! 📄 Estimating treatment effects in trials with outcome data truncated by death: A case study on aligning estimators with estimands. 🔗 Read the full paper: journals.sagepub.com/doi/10.1177/...

🎓 Thinking about a PhD in clinical trial #methodology? We have two funded PhD opportunities for students passionate about trial design and statistical methods: • One in estimands • One in non-inferiority trials 🔗 More info and how to apply here: buff.ly/lCpqcF6 @mrcnihrtmrp.bsky.social

Let’s kick off Wednesday with another #ProudestOf moment from our amazing team at the Unit! Today, we’re spotlighting Paul Hyams, our Facilities, Health and Safety Manager at ICTM. We asked Paul what he’s #ProudestOf in his work at the Unit 👇

📈 Exciting news from #ESMO25! First results from the RAMPART trial show that a combination of 2 immunotherapy drugs (durvalumab and tremelimumab) helps prevent kidney cancer from coming back after surgery. 🔗 Read the full story: www.mrcctu.ucl.ac.uk/news/news-st...

Over the weekend, we announced new findings from the ICON8B trial at #ESMO25. Results show that weekly chemotherapy with bevacizumab improves survival of women with advanced #OvarianCancer compared to having it once every 3 weeks. 🔗Learn more on our website: www.mrcctu.ucl.ac.uk/news/news-st...

🚨Big news in Parkinson’s research! We are excited to share that the largest-ever Parkinson’s disease trial has launched across the UK. Using our multi-arm, multi-stage #MAMS design, the #ejsactpd trial aims to stop or slow the progression of the disease. 🔗 More www.mrcctu.ucl.ac.uk/news/news-st...

#ESMO25 is fast approaching… If you are attending, check out the details of talks and posters featuring MRC CTU at UCL trials and meta-analysis work 👇

Wednesdays are our #ProudestOf days at the Unit! This week, meet Berta Terre Torras, our Science Communications Officer and host of the #TrialTalk podcast. We asked Berta what she’s #ProudestOf in his work at the Unit 👇

To mark #BreastCancerAwarenessMonth, we are spotlighting the Add-Aspirin trial, which explores whether taking aspirin regularly after treatment could help stop breast cancer (and other cancers) from coming back. 🔗 Find out more about Add-Aspirin: www.mrcctu.ucl.ac.uk/studies/all-...

📊 Join this UCL @mrcctu.bsky.social Capacity Strengthening Hub webinar! In collaboration with @lshtm.bsky.social 's ISEP team 🗓️ 13 Oct 2025 | ⏰ 10:00–11:30 UTC+1 | 💻 Online 🎙️ Speakers: Michelle Clements, Andrew Abaasa, Philip Ayieko, Vicky Simms 🔗 Register here: shorturl.at/hGtLq

Let’s brighten up your Wednesday with another #ProudestOf moment from our brilliant team at the Unit! This week, we’re spotlighting Yath Yogeswaran, one of our fantastic Research Fellows and a medical statistician on the STAMPEDE2 trial. Here's what Yath is #ProudestOf from his work at the Unit 👇

🏆 Nominations for the Penta Brighter Future Award are open! Don’t miss the opportunity to celebrate inspiring contributions to maternal and child health worldwide with @pentafoundation.bsky.social 🔗 Nominate someone making a difference: penta-id.org/bfa/

Heading to #ESMO2025 in Berlin? Make sure you catch the latest updates from our #ClinicalTrials in prostate, ovarian & kidney cancer, plus the STOPCAP meta-analysis. Check out the full list of our posters & presentations in the image below 👇 @myesmo.bsky.social

Halfway through the week and full of pride… It’s time for another #ProudestOf moment! This week, we’re spotlighting Gabriela Toledo, one of our brilliant Post-doctoral Research Fellows. She shares how building a supportive and friendly network has made all the difference in her work.

💻 Come along to our next Capacity Strengthening Hub webinar with @tghn-news.bsky.social on “How to be a good trial statistician”. 🗓️ 13 October 2025 🕙 10:00-11:30 BST 📍 Online (Zoom) Register now: lnkd.in/e4RYCqNU

It’s time for another #ProudestOf Wednesday! Today, we’re spotlighting Matteo Quartagno (@matteoq21.bsky.social), Principal Research Fellow, who’s advancing the field with innovative trial designs as part of our #Methodology research. Here’s what Matteo is #ProudestOf from his work at the Unit 👇

Continuing the legacy of #STAMPEDE in advancing #ProstateCancer care, we celebrate #UrologicalCancerAwarenessMonth by spotlighting STAMPEDE2. This new trial explores 2 innovative treatments: 🔹 Targeted radiation 🔹 Nuclear medicine therapy And plans to add some more. 🔗Learn more:

It’s Wednesday, which means it’s time for another #ProudestOf moment from our incredible team at the Unit! This week, we spotlight Asiyya Tahsin, one of our fantastic research administrators and a member of our #PPI group. We asked Asiyya what she’s #ProudestOf in her work at the Unit 👇

To celebrate #UrologicalCancerAwarenessMonth, we look back at the many achievements of #STAMPEDE, the largest ever trial in advanced #ProstateCancer. After 20 years and 12,000 participants, it has tested 10 different treatments and changed the standard-of-care 4 times. Read more:

To celebrate #WorldSepsisDay, we’re proud to share our work on NeoSep1, a groundbreaking #ClinicalTrial comparing multiple antibiotic regimens to treat babies with #sepsis. 🎧 This #TrialTalk episode explores NeoSep1's rationale and impact 👇