What's in yer basement?

"Breakthroughs rarely announce themselves on the good days — they are earned quietly, by refusing to quit on the lousy ones, even when impostor syndrome tells you otherwise." open.substack.com/pub/leaopel/...

We sequenced the anti-RSV-F antibody 131-2a by mass spec and determined its epitope by cryoEM. New insights in postfusion specific binding and antigenic site I. Now published in ACS Infectious Diseases @pubs.acs.org. pubs.acs.org/doi/10.1021/... @xdh.bsky.social @hangryhobbit.bsky.social

Structural biologist Pavel Plevka from CEITEC Masaryk University has been elected a new member of the prestigious European Molecular Biology Organization (@embo.org). Congratulations! 👏 Read more here ➡️ www.ceitec.eu/pavel-plevka... #CEITECScience @plevkalab.bsky.social

Scripps Research and @pittofficial.bsky.social capture the first cryo-EM & cryo-ET images of a virus infecting TB-causing Mycobacteria, revealing an unexpected infection mechanism that could inform phage therapies for drug-resistant TB, per @cellpress.bsky.social.

Excited to share our preprint on the molecular architecture of heterochromatin in human cells 🧬🔬w/ @jpkreysing.bsky.social, @johannesbetz.bsky.social, @marinalusic.bsky.social, Turoňová lab, @hummerlab.bsky.social @becklab.bsky.social @mpibp.bsky.social 🔗 Preprint here tinyurl.com/3a74uanv

We continue working on the plans for the "Woodstock of Bioloy 2 & Night science in Prague" meeting and if you don't sign up you're totally crazy. A once in a life time opportunity and it'll be sold out soon. Go to the website and sign up now before it's too late!

I am very happy to announce that we solved the in-virus #cryoEM structure of the #HIV matrix protein. The structure helped us to resolve a long mystery in HIV biology. A🧵1/5 Read more in Nature: www.nature.com/articles/s41... 🧪

We sequenced the anti-RSV-F antibody 131-2a by mass spec, then mapped its epitope by cryoEM. It's widely used to study the antigenic landscape of F, but its sequence wasn't known. Check it out in our new preprint and find it on Addgene: www.biorxiv.org/content/10.1... www.addgene.org/Joost_Snijder/

@hangryhobbit.bsky.social glad to see you here on 🔵bsky, marta 🙂 let's celebrate Happy #WorldPhageDay 🎉 here too... #PhageSky

2/15 "How are you" is often deemed a 'pointless' or 'filler' question, to which the socially acceptable answer might be a lie ("fine, how are you?"). "How are you" should not be taken as an opportunity to "discuss the crushing reality of existence", says Machell's Guide to Surviving Modern Life.

🚀Announcing my first (co)first-author manuscript 🚀 "Cell attachment and tail contraction of S. aureus phage phi812" 🔗 bit.ly/Phi812 Explore the structural details of phage interaction with Gram+ bacteria 🤯 #PhageTherapy #cryoEM 🧪 | 🧬🧶 | 🦠 1/11

You're looking at one of the first electron micrographs of T-even bacteriophage, taken by Tom Anderson of RCA labs, published with Luria & Delbrück. On seeing the images, famed immunologist Jacques Bronfonbrenner exclaimed: “Mein Gott, they’ve got tails!”

Assistant Professor position in Molecular Microbiology at Utrecht University, app deadline Jan 31,2024. #AcademicSky 🧪 www.uu.nl/en/organisat...

Back to basics 🔬