So much work still to do to break the glass ceiling! Analysis of millions of biomed & life science articles reveal that female-authored articles spend longer under review than comparable male-authored ones @plosbiology.org 🧪 plos.io/4658FZN

My wife has been HIV+ for 34 years. She’s alive today b/c work of activists who destigmatized the virus, pushed medical science to adapt & find ways to treat it, & advocated for gov health programs that helped fund her care. The current U.S. regime may want to go back in time, but we won’t let them.

"Remarkably, the bacterium that makes methylenomycin A and pre-methylenomycin C lactone -- Streptomyces coelicolor -- is a model antibiotic-producing species that's been studied extensively since the 1950s. Finding a new antibiotic in such a familiar organism was a real surprise." 🧪

WHO reports 1 in 6 bacterial infections worldwide are antibiotic-resistant, with resistance rising sharply since 2018. Gram-negative bacteria like E. coli and K. pneumoniae pose the biggest threat. Action on #AMR surveillance and responsible antibiotic use is needed. www.who.int/news/item/13...

IBRO President-Elect, Shubha Tole, together with other speakers at the 2025 Brain Days #UNGA80, is highlighting the need for international collaboration to advance neuroscience. What do you think can help make this a reality in the global #neuroscience community? @braincouncil.eu

Many of the most complex and useful functions in biology emerge at the scale of whole genomes. Today, we share our preprint “Generative design of novel bacteriophages with genome language models”, where we validate the first, functional AI-generated genomes 🧵

In a new preprint from @brianhie.bsky.social's lab, the team reports the first generative design of viable bacteriophage genomes. Leveraging Evo 1 & Evo 2, they generated whole genome sequences, resulting in 16 viable phages with distinct genomic architectures.

@mblokesch.bsky.social Umm, you don't have to reply but I would really appreciate if you share your wisdom in this matter. You are a PI and you must have seen your PhD trainees journey through all ups and downs, I really need to understand how does one overcome the wet lab work associated anxiety?

We had a life before this genocide. We had dreams. We cannot bear all this terrible pressure. We have our dreams. We want to live like the rest of the people in this world. We are exhausted. Please hear our calls. Stop this massacre. We need you. Please Help us.😔😔 chuffed.org/project/save...

Published in Communications Biology - probably the first time I’ve seen such a detailed example of prompt engineering in a paper that has absolutely nothing to do with AI. Worth reading the full prompt in the methods as it’s quite detailed and could be useful to others www.nature.com/articles/s42...

Setting aside the ethical and environmental concerns of AI, I'm really offended by a bunch of elite dudes telling us our minds aren't good enough when they've had to steal everything human minds have created to create their pretend mind and it doesn't even work right!

#Canada #Ontario #crime Samagra was just 23. Please share with as many Canadian friends as you can, the culprit needs to be brought to justice.

🇨🇭🇪🇺 Just Published in Royal Society Open Science! A scoping review on metrics to quantify reproducibility: royalsocietypublishing.org/doi/10.1098/... Ever conducted a replication and pondered when/how to conclude if it was (un)successful? We have just the paper for you (led by Rachel Heyard)! 1/14

this is one of the worst crimes in human history and the entire global north and all of us in it share the responsibility

The murderer is still on lose. Please share.

#Canada #Ontario #crime Samagra was just 23. Please share with as many Canadian friends as you can, the culprit needs to be brought to justice.

The Nazis burned books, attacked universities, and crippled German science. The MAGAs delete websites, attack universities, and cripple American science. The website www.globalchange.gov of the mandated Global Change Research Program & all the National Climate Assessment reports has been deleted.

Chatbots — LLMs — do not know facts and are not designed to be able to accurately answer factual questions. They are designed to find and mimic patterns of words, probabilistically. When they’re “right” it’s because correct things are often written down, so those patterns are frequent. That’s all.

#booksky #writingcommunity

62M, on hemodialysis with diabetes, gets gene-edited porcine kidney with 69 genomic edits. Xenograft shows immediate function, creatinine ⬇️ promptly. PMID:39927618, N Engl J Med 2025, @NEJM https://doi.org/10.1056/NEJMoa2412747 #Medsky #Pharmsky #RNA #ASHG #ESHG 🧪

There are 2 previous historical cases of countries destroying their science and universities, crippling them for decades: Lysenkoism in the USSR and Nazi Germany. The Trump administration will be the 3rd. It's not just budgets but research, institutions, expertise, and training the next generation.

Each time you ask an AI chatbot a question, it sends a request to a data center and strains an increasingly scarce resource: water. A 🧵on our investigation into how the data centers that power AI are increasingly being built in highly water-stressed places: www.bloomberg.com/graphics/202...

It’s time to reconsolidate a counterculture and politics against this shit. Science, art, medicine, poetry, philosophy as the beautiful life, the fullness of human civilization, that they want to destroy. Humanism, not cynicism, not slop, not tech “””nerd””” culture

SCAM ALERT. This is a fake conference that ripped off my and other people’s names to trick people into registering. There is no such conference that I or the others shown were invited or agreed to. We are working to try to get this fraud taken down from the web. chemsymposia.com

Literally a month ago, we got news that an mRNA vaccine showed promise against pancreatic cancer, one of the deadliest Not enough words to describe how willfully destructive this is

Trump and Musk are basically trying to deskill America: 1) kill all white-collar jobs and replace them with AI 2) kill universities 3) use tariffs to turn the U.S. into an economic island manufacturing, oil and ag hub 4) empty the cities 5) push men into manual labor & women back into the kitchen

I am somehow for the first time ever reviewing for PNAS and their reviewer instructions include this BANGER of a line: "The purpose of peer review is not to demonstrate proficiency in identifying flaws" Print it in eleventy point font and hang it from the hillside. Scream it from the rooftops.

one thing i keep thinking about is how there is simply no way to design a constitutional system that can resist authoritarian incursion if participants in that system do not actually care that much

It’s amazing to find out at this late date how much the rule of law depended on people simply deciding, on a voluntary, daily basis, not to break the law.

I mean seriously wtf is this? It's not even been a few years since the disaster that was the decades long sexual abuse of the US women gymnasts; now 51 US senators vote for mandatory genital inspections of girls and women?! Has hatred for transgender athletes driven us crazy?! (the answer is yes)

Had a conversation this morning that reminded me of this thread. In short, I don't think efficiency and innovation go hand in hand

“If you're not careful, the newspapers will have you hating the people who are being oppressed, and loving the people who are doing the oppressing.” A classic quote from Malcolm X, who was assassinated 60 years ago today.

WOW — there’s a stat that every single American should know.

As always, @chriswarcraft.bsky.social is a real one.

Pritzker: If we don’t want to repeat history, then for god’s sake, in this moment, we better be strong enough to learn from it.

@science.org RNA polymerase II at histone genes predicts outcome in human cancer 🧬💊 @fredhutch.bsky.social @hhmi.bsky.social www.science.org/doi/10.1126/...

The Partition of India displaced 20 million people, killed almost 2 million & created a refugee crisis whose effects are still in play over 70 years later, if you actually think it's a model for anything but massive catastrophe, you should not only not be employed here you should be in a padded cell

Saying "don't worry, they'll stop it, our scientific research is valuable and profitable and important to tuition-paying students" suggests you've misunderstood that it has been an ideological project all along. The humanities were all those things too! It was never just about profit and loss.

A shout-out to my #Yale colleague Jason Stanley's new book. Want to know why #Trump/#Musk are going after universities, whitewashing federal agencies' histories, taking down photos, etc.? This is what fascists do.

A useful metaphor on the indirects situation: “It’s like saying the crew and plane are the only real costs, and you have to run the entire ground, scheduling, and other parts of the airline on 15% of the crew and fuel costs.”

So who’s got more experience than I do in political advocacy for science & would be interested in sharing that knowledge with the community of newly politically engaged researchers?

Whenever you hear someone sneer about scientific research that seems useless to them — “they’re studying the spit of lizards?!” — remind them that’s exactly how we got Ozempic. globalnews.ca/news/9793403...

It’s been a tough few weeks. My 10yo daughter was diagnosed with a very rare, aggressive cancer called interdigitating dendritic cell sarcoma (IDCS). I’m reaching out to identify clinicians/patients who have encountered pediatric IDCS or other (non-LCH) dendritic or histiocytic sarcomas cases.