Highlights from my talk yesterday on Alport syndrome spectrum of disorders. (since no one posted it, I'll have to do it myself) Variants in type IV collagen cause a wide spectrum of disease. #KidneyWk 🧵

Required reading for cell biologists to get a sense of basic statistical principles! www.nature.com/articles/s41...

Please repost - Multiple PhDs available www.findaphd.com/phds/project... www.findaphd.com/phds/project... www.findaphd.com/phds/project...

Our paper on podosome regulation by myosins 1e/f is now online. We introduce the concept of the podosome base, a region of plasma membrane-associated components 🔬 Cool collaboration with @renaudpoincloux.bsky.social‬ and Krendel labs www.sciencedirect.com/science/arti...

I'm up to 75 responses. I would be very thankful if you fill this out 😀 Median time to take it is 2.6 minutes. I promise it only takes significantly longer if you would like to leave me a rant about efforts that are a waste of time. Those make me laugh, though

New to bioimage analysis & Python? Want to quantify fluorescence microscopy images, explore segmentation & classification, & try colocalization analysis using Python? If so, this course is for you! Apply by June 1st! 🔬💻https://iac.hms.harvard.edu/bobiac/2025

Moving obituary of David Stephens, "in many ways, the perfect academic" journals.biologists.com/jcs/article/...

Thrilled to be featured in The New York Times! @nytimes.com Fantastic piece by @jack-tamisiea.bsky.social on our discovery of the role of physical forces in evolution! With insightful comments from @wcratcliff.bsky.social!

A follow-up to my quote of the day this morning: A short Bluetorial about Vannevar Bush and his legacy

Hey #chemsky and beyond, with all that is going on, I am curious what expensive, high margin molecules we could provide to the community for free. What things do you use all the time, cost way too much, and would make a difference? Alexa Fluor 488 NHS? Other dyes? Other molecule?

Please share: @delauro.house.gov is cochair of the US House Congressional Rapid Response Task Force and Litigation Working Group. They are looking for instances where the impoundment and restriction of NIH/NSF funds is having a negative impact. Submit examples here delauro.house.gov/constituent-...

PREPRINT OUT ✨ "hack" your microscope to work as a 3D printer! print micrometer sized features at cm scale. a method for easy and cheap microfabrication, with a focus on biological applications. THREAD ↓ www.biorxiv.org/content/10.1...

Reposting faculty job opportunities! Two Empire Innovations Scholar positions at the Assoc. Professor level are open in our dept (CellDevBio) and Biochem. Mol. Bio. dept. Seeking funded faculty w. interests in microscopy and related areas. Apply at bit.ly/UpstateEIP

And finally a funny trick for actin aficionados: label actin with different probes and use their differential staining properties to identify actin structures within cells: www.biorxiv.org/content/10.1...

Of these, 97 received funding from the National Institute of General Medical Sciences (NIGMS) (with some also receiving funding from other institutes). 97/174 = 56% while NIGMS typically receives 7% of NIH budget. 3/n

Self-generated gradients guide collective cell movement -but often different cell types must move together, e.g. in immune response. We develop a theory of self-generated chemotaxis in mixed populations -are there optimal principles for this cooperation?🤔 www.biorxiv.org/content/10.1...

Thank you for hosting our team and making this project a success! Here is a macrophage playing beach volleyball with IgG-coated beads, courtesy of Tyler Paul, Yoseph Loyd, and @scientistrachel.bsky.social !

I am immensely excited and proud of the official launch of Imaging Southeast Asia (iSEA) yesterday. This is one of the fastest growing #microscopy communities I have witnessed across the globe! Check them out, and join at imagingsea.org 🧪

#CellBio2024 - if you would like to learn more about our job posting for an established investigator with interests in microscopy, image analysis, optogenetics etc., feel free to reach out - I would be happy to chat at the meeting! bit.ly/UpstateEIP

Optogenetic and chemical genetic tools for rapid repositioning of vimentin intermediate filaments https://www.biorxiv.org/content/10.1101/2024.11.21.624725v1

Bone remodeling is traditionally driven by osteoblasts and osteoclasts, but our study reveals a third essential player: "Type R capillaries". 🦴🔬😍 Excited to share my PhD work from Ralf H. Adams lab, now published in @natureportfolio.bsky.social Nature Cell Biology. www.nature.com/articles/s41...

A new microtubule end-binding protein (called EB-SUN) was discovered in Drosophila by Sun Kim, a graduate student in our lab together with Steve Rogers, a former graduate student, now on faculty in UNC. www.molbiolcell.org/doi/10.1091/...

Nice work from Yasushi Okada and colleagues on the development of fluorescence lifetime biosensors for ATP, cAMP, citrate, and glucose using mTurquoise2 www.cell.com/cell-reports...

Anillin tunes contractility and regulates barrier function during Rho flare-mediated tight junction remodeling https://www.biorxiv.org/content/10.1101/2024.11.20.624537v1

Lots of posters from SUNY Upstate Cell Dev Biology at #cellbio2023! Please stop by and talk to the presenters!