Danielle
@dmackowsky.bsky.social
đ€ 120
đ„ 235
đ 34
Hail to Pitt with some Mass Spec on the side
reposted by
Danielle
BioMassSpec
2 days ago
Validation of the U.S. Food and Drug Administrationâs Method for Detection of Per- and Polyfluoroalkyl Substances Analytes in Food and Feed: First Action 2025.06
#JAOAC
#MassSpec
academic.oup.com/jaoac/articl...
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Validation of the U.S. Food and Drug Administrationâs Method for Detection of Per- and Polyfluoroalkyl Substances Analytes in Food and Feed: First Action 2025.06
AbstractBackground. The AOAC Stakeholder Panel on Strategic Food Analytical Methods approved AOAC INTERNATIONAL Standard Method Performance Requirements (S
https://academic.oup.com/jaoac/article/doi/10.1093/jaoacint/qsag007/8456565
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Danielle
ASMS
2 days ago
Conference experience AND a stipend? Yes, please!
#ASMS
Student Assistant Work Stipends provide $300 to students who help out during the Annual Conference, with scheduling that takes your presentation day into account. Apply before the 6th:
https://bit.ly/49YsR1S
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Student Work Stipends
https://bit.ly/49YsR1S
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Danielle
Katie Gitin
3 days ago
đšPhiladelphia Researchersđš
@sciex.bsky.social
is hosting a Researcher Recess on 2/19 at White Dog Cafe in University City including: -Delicious food & refreshing drinks -Fun games and networking -A chance to win exciting prizes Save your spot here:
sciex.com/Hidden/amer-...
#MassSpectrometry
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Researcher Recess
https://sciex.com/Hidden/amer-lp/clinical/researcher-recess?utm_source=outlook&utm_medium=email&utm_campaign=clinical&utm_term=r-researcher%20recess%20pa-jan-26&utm_content=landing%20page
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Danielle
one dozen rats at a keyboard
4 days ago
in spite of everything, I am somehow still excited about Phillies baseball coming back.
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Huge for MS solvents!
add a skeleton here at some point
12 days ago
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Danielle
PastelBio
15 days ago
Special Issue on Women in Proteomics
www.mcponline.org/ar...
---
#proteomics
#prot-paper
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reposted by
Danielle
PastelBio
15 days ago
Intact Proteoform Analysis by Capillary ElectrophoresisâMass Spectrometry. Are We There Yet?
onlinelibrary.wiley....
---
#proteomics
#prot-paper
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reposted by
Danielle
Princess Vimentin PhD | Cancer Biologist
15 days ago
đ§ȘIMPORTANT! This graphic explains how science all over the US is funded. Congress approved a 2% increase in the
#NIH
budget for FY 26. Buried in the bill- Shift of ~40% of grants to MYF. This will still result in a 35% DECREASE in the NUMBER of grants funded per yr. Russel Vought is behind this.
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Danielle
Sarah E Hancock
19 days ago
Found on LinkedIn alongside text describing how PCR works. đ.
#TeamMassSpec
#massspectrometry
#science
#badai
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reposted by
Danielle
Science Homecoming
25 days ago
Our collective efforts to save science are working. Gift article
www.nytimes.com/2026/01/10/s...
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Congress Is Reversing Trumpâs Steep Budget Cuts to Science
https://www.nytimes.com/2026/01/10/science/trump-science-budget-cuts-congress.html?unlocked_article_code=1.DlA.NS_5.TU5U-BieElVv&smid=nytcore-ios-share
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Danielle
NBC News
26 days ago
The Pittsburgh Steelers awarded Super Bowl tickets to AJ Owens, a fan who founded a food bank to give back to his community.
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Danielle
Kevin A. Scott
about 1 month ago
Ok here it is - out of 44 FDA approvals this year, 31 are small molecules (70%), 26 of those are oral drugs (84%), 22 of them are chiral (71%). This is the largest number and percentage of chiral FDA approved molecules in a single year. Fitusiran is not a small molecule, bonus.
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Big 2008 Sun Bowl vibes
#pittbs
about 1 month ago
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1
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reposted by
Danielle
BioMassSpec
about 2 months ago
A Streamlined High Performance Liquid Chromatography with Tandem Mass Spectrometry Based Workflow for Rapid Screening of Cellular Accumulation of Small Molecules
#ChemMedChem
chemistry-europe.onlinelibrary.wiley.com/doi/10.1002/...
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A Streamlined High Performance Liquid Chromatography with Tandem Mass Spectrometry Based Workflow for Rapid Screening of Cellular Accumulation of Small Molecules
This study uses six small-molecule inhibitors to evaluate optimal cellular accumulation assay conditions in a 96-well format with high performance liquid chromatography with tandem mass spectrometry ...
https://chemistry-europe.onlinelibrary.wiley.com/doi/10.1002/cmdc.202500753
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1
2 months ago
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reposted by
Danielle
BioMassSpec
3 months ago
Multistage Tandem Mass Spectrometry Using an Electron-Activated Dissociation Device with a Linear Ion Trap and Structural Identification of Cardiolipins
#AC
pubs.acs.org/doi/10.1021/...
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https://pubs.acs.org/doi/10.1021/acs.analchem.5c05400
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1
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reposted by
Danielle
BioMassSpec
3 months ago
Characterization and Elucidation of the Fragmentation Pathway of 17 Nitazenes by Liquid Chromatography High-Resolution Mass Spectrometry Using Collision-Induced Dissociation and Electron-Activated Dissociation
#JASMS
pubs.acs.org/doi/10.1021/...
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Characterization and Elucidation of the Fragmentation Pathway of 17 Nitazenes by Liquid Chromatography High-Resolution Mass Spectrometry Using Collision-Induced Dissociation and Electron-Activated Dis...
Nitazenes, a class of new psychoactive substances, have emerged as a significant public health and safety concern due to their widespread abuse. While various detection methods, particularly mass spec...
https://pubs.acs.org/doi/10.1021/jasms.5c00081
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1
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reposted by
Danielle
BioMassSpec
4 months ago
Rapid LC-QTOF-MS screening method for semi-synthetic cannabinoids in whole blood
#JAT
academic.oup.com/jat/article/...
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Validate User
https://academic.oup.com/jat/article/doi/10.1093/jat/bkaf095/8294146
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1
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reposted by
Danielle
Jim Hammett
4 months ago
Heard a bunch of old guys singing in an Irish pub in Cooperstown. Turns out they were members of the Pitt glee club in the 70âs. Here is âHail to Pittâ courtesy of them:
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reposted by
Danielle
Sickos Committee
4 months ago
We made a Pitt Version of this too. Fat Roc as Big Pun.
add a skeleton here at some point
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reposted by
Danielle
BioMassSpec
4 months ago
Enhancing glycopeptide annotation and glycan localization using electron activated dissociation through a multiplexed parallel reaction monitoring design of experiments
#JProteomics
#MassSpec
www.sciencedirect.com/science/arti...
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Enhancing glycopeptide annotation and glycan localization using electron activated dissociation through a multiplexed parallel reaction monitoring design of experiments
We present an optimized electron activated dissociation (EAD) methodology, based on hot electron capture dissociation, for liquid chromatography-tandeâŠ
https://www.sciencedirect.com/science/article/pii/S1874391925001733
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reposted by
Danielle
Consortium for Top-Down Proteomics
4 months ago
Join us Oct. 16 for the VENDOR SHOWCASE at Proteoform Thursday. Great lineup of speakers presenting the latest tech and apps for top-down proteomics.
us06web.zoom.us/meeting/regi...
#proteomics
#massspec
#proteoforms
#Thermo
#Bruker
#Sciex
#Agilent
#NewObjective
#ImmPro
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reposted by
Danielle
Merriam-Webster
5 months ago
We want it this way.
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I am hiring! Do you have
#massspec
experience and are looking to get out of the lab and into sales?
#chemjobs
jobs.danaher.com/global/en/jo...
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Territory Manager, Mass Spectrometry - New Jersey job in Newark, New Jersey, United States of America | Sales jobs at Danaher
Apply for Territory Manager, Mass Spectrometry - New Jersey job with Danaher in Newark, New Jersey, United States of America. Sales at Danaher
https://jobs.danaher.com/global/en/job/R1294504/Territory-Manager-Mass-Spectrometry-New-Jersey
6 months ago
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reposted by
Danielle
BioMassSpec
6 months ago
Endocannabinoid and steroid hormone levels during and after pregnancy in fingernail samples from mothers and their infants
#Steroids
#MassSpec
www.sciencedirect.com/science/arti...
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Endocannabinoid and steroid hormone levels during and after pregnancy in fingernail samples from mothers and their infants
Stress exposure and protective biological factors such as steroid hormones and endocannabinoids (eCBs) play a crucial role in pregnancy and birth outcâŠ
https://www.sciencedirect.com/science/article/pii/S0039128X25001047
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reposted by
Danielle
BioMassSpec
6 months ago
Accelerating Characterization of Therapeutic Antibodies: A Comparative Assessment of icIEF-UV/MS and the Traditional Fractionation Workflow
#JASMS
pubs.acs.org/doi/10.1021/...
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Accelerating Characterization of Therapeutic Antibodies: A Comparative Assessment of icIEF-UV/MS and the Traditional Fractionation Workflow
Accurate characterization of charge variants in biologics is crucial to uphold stringent quality standards ensuring the safety and efficacy of biotherapeutic products and regulatory requirements for t...
https://pubs.acs.org/doi/10.1021/jasms.5c00058
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reposted by
Danielle
Chris Peak
6 months ago
Even now, almost 30 years later, you drive down this street and feel like you're driving toward Something. Whatever it is, Something is happening and you're driving toward it.
add a skeleton here at some point
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reposted by
Danielle
BioMassSpec
7 months ago
High-Throughput Detection and Quantitation of Metal Contamination with Acoustic Ejection Mass Spectrometry
#JASMS
pubs.acs.org/doi/10.1021/...
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https://pubs.acs.org/doi/10.1021/jasms.5c00182
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reposted by
Danielle
The Athletic
7 months ago
If you know, you know. Happy Bobby Bonilla Day to all who observe.
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reposted by
Danielle
BioMassSpec
8 months ago
Acoustic ejection mass spectrometry: An integrated pipeline for ultra-high throughput screening, reactivity profiling, and potency analysis of covalent BTK inhibitors
#SLASTechnol
www.slas-technology.org/article/S247...
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Acoustic ejection mass spectrometry: An integrated pipeline for ultra-high throughput screening, reactivity profiling, and potency analysis of covalent BTK inhibitors
Covalent drug discovery has garnered renewed interest due to its potential to target proteins previously considered
https://www.slas-technology.org/article/S2472-6303%2825%2900065-2/fulltext
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reposted by
Danielle
PastelBio
8 months ago
Sciex/Evosep | Selecting optimal ZT Scan DIA acquisition methods on the ZenoTOF 7600+ system for quantitative proteomics
sciex.com/tech-notes...
---
#proteomics
#prot-other
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reposted by
Danielle
Chris Ashwood
8 months ago
ZenoTOF 8600
#ASMS2025
summary: - Up to 10x more sensitive than 7600+ (Hardware improvements DJet/QJet ion guides, OptiFlow Pro source and TOF optics) - Up to 858 Hz MS2 (ZT Scan DIA 2.0) - Lower contamination with 7500+ mass guard tech (so maybe no 8600+ is needed) - EAD negative mode up to 50 KE
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reposted by
Danielle
HispanicLatinX_MS
9 months ago
The Hispanic and LatinX in MS Group will attend the SCIEX Inclusion and Belonging Networking Event! Join us for an evening of connection and community. Weâll be giving away prizes to our followers. Youâll recognize the HLXMS members by the badges featuring our logo!
#ASMS2025
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4
3
reposted by
Danielle
BioMassSpec
9 months ago
Absolute Quantitation of Neopterin as an Endogenous Pharmacodynamic Biomarker: The Successful Method Development, Validation, and Use of a Surrogate Matrix for Clinical Sample Analysis
#AnBiochem
#MassSpec
www.sciencedirect.com/science/arti...
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Absolute Quantitation of Neopterin as an Endogenous Pharmacodynamic Biomarker: The Successful Method Development, Validation, and Use of a Surrogate Matrix for Clinical Sample Analysis.
Biomarkers are playing an increasing role in the drug discovery and drug development process. Molecular biomarkers pose a bioanalytical challenge due âŠ
https://www.sciencedirect.com/science/article/pii/S0003269725001319
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0
1
reposted by
Danielle
BioMassSpec
9 months ago
A Validated Screening and Confirmation Method for 946 Drugs and Metabolites Using LC-QTOF-MS with SWATH Acquisition
#JAT
academic.oup.com/jat/advance-...
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A Validated Screening and Confirmation Method for 946 Drugs and Metabolites Using LC-QTOF-MS with SWATH Acquisition
Abstract. A streamlined liquid chromatography quadrupole time-of-flight mass spectrometry (LC-QTOF-MS) method utilizing protein precipitation and filtratio
https://academic.oup.com/jat/advance-article-abstract/doi/10.1093/jat/bkaf037/8125303?redirectedFrom=fulltext
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In honor of the draft, what team would your dog play for? This guy would be a Raider: kinda a jerk, rocks the color black, would thrive as a Vegas bro.
10 months ago
0
1
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reposted by
Danielle
BioMassSpec
10 months ago
Quantification of total sBCMA in human plasma by peptide-level immunocapture LC-MS/MS
#JMSACL
www.sciencedirect.com/science/arti...
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Quantification of total sBCMA in human plasma by peptide-level immunocapture LC-MS/MS
B-cell maturation antigen (BCMA) is a membrane protein that is overexpressed in multiple myeloma cells and can be targeted with biotherapeutic agents.âŠ
https://www.sciencedirect.com/science/article/pii/S2667145X25000136
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1
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reposted by
Danielle
BioMassSpec
10 months ago
Optimization of Parallel Artificial Liquid Membrane Extraction for the Determination of Over 50 Psychoactive Substances in Oral Fluid Through UHPLCâMS/MS
#DTA
analyticalsciencejournals.onlinelibrary.wiley.com/doi/full/10....
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Optimization of Parallel Artificial Liquid Membrane Extraction for the Determination of Over 50 Psychoactive Substances in Oral Fluid Through UHPLCâMS/MS
This study is related to the development of a microextraction method for the determination of 56 psychoactive substances in oral fluid. Sample clean-up is obtained by parallel artificial liquid membr...
https://analyticalsciencejournals.onlinelibrary.wiley.com/doi/full/10.1002/dta.3894
0
0
1
reposted by
Danielle
Compound Interest | Chemistry infographics
11 months ago
Happy
#StPatricksDay
! âïž What makes the bubbles in a glass of Guinness fall, and what gives the beer its dark colour? This graphic in
@cenmag.bsky.social
has the answers:
cen.acs.org/articles/93/...
#ChemSky
đ§Ș
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If the NCAA or anyone touches March Madness that will be unforgivable
11 months ago
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1
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reposted by
Danielle
The Sickos CBB Committee
11 months ago
VCU WINS THE A10!
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Rolling out the Cart. Nothing like midday BE Tourney tip off
add a skeleton here at some point
11 months ago
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Hey
#PittBS
May I invite you to join the VCU hoops bandwagon? Pros: I bet you already own black & gold AND their football team is undefeated!
11 months ago
0
1
0
reposted by
Danielle
PastelBio
11 months ago
News in Proteomics Research blog post | FFPE vs Fresh frozen tissues - very few differences?!?!?
proteomicsnews.blogs...
---
#proteomics
#prot-other
1
1
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reposted by
Danielle
Jeff Mugridge
11 months ago
I wrote an opinion piece for my hometown newspaper in Central NY about attacks on NIH/NSF/research and why this harms not just US science but local jobs and economies. Thanks
@sciencehomecoming.bsky.social
for sparking these efforts! I encourage others to join in!
www.syracuse.com/opinion/2025...
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Protect science funding driving innovation, investment in Syracuse (Guest Opinion by Jeffrey Mugridge)
Severe cuts to budgets and staff threaten to undermine the next generation of American scientists, writes professor who discovered his love of science as a Liverpool High student.
https://www.syracuse.com/opinion/2025/02/protect-science-funding-driving-innovation-investment-in-syracuse-guest-opinion-by-jeffrey-mugridge.html
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reposted by
Danielle
Jeremy Berg
12 months ago
From
@cbssundaymorning.bsky.social
this morning. The citizens of Pittsburgh and Allegheny County eagerly stuck out their arms to try to stop the scourge of polio. 1/3
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reposted by
Danielle
Sickos Committee
12 months ago
It's Girl Scout Cookie season, but don't forget that depending on where you live, you might be getting the superior cookies from Little Brownie Bakers (REAL Samoas) or the inferior ones (Caramel Delites). Also, the LBB thin mints are in every way superior.
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reposted by
Danielle
PastelBio
12 months ago
Overlap of Formalin-Fixed Paraffin-Embedded and Fresh-Frozen Matched Tissues for Proteomics and Phosphoproteomics
pubs.acs.org/doi/ful...
---
#proteomics
#prot-paper
0
8
2
reposted by
Danielle
US HUPO
12 months ago
When is CID not enough for your research? At SCIEX, weâve found some novel applications of hybrid and electron-based fragmentation to better characterize PTMs, including phospho- and glycopeptides. How else can EAD help biological insights?
#USHUPOSponsor
#SponsoredPost
0
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Are you a PhD mass spec expert in
#omics
? Check out this job- field based and can live in the NE/Mid-Atlantic
jobs.danaher.com/global/en/jo...
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Advanced Workflow Specialist (CT, NJ, NY, PA, DE) job in Newark, New Jersey, United States of America | Sales jobs at Danaher
Apply for Advanced Workflow Specialist (CT, NJ, NY, PA, DE) job with Danaher in Newark, New Jersey, United States of America. Sales at Danaher
https://jobs.danaher.com/global/en/job/R1283976/Advanced-Workflow-Specialist-CT-NJ-NY-PA-DE
12 months ago
0
1
0
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