Finally, Jennifer Asimit will discuss leveraging phenotypic similarity and ancestry diversity in cardiometabolic genetics. Multi trait and multi ancestry methods for fine-mapping are emerging but challenging to implement

Final session - Gareth Hawkes talks about using WGS to examine the convergence of rare and common traits. Preprint: www.biorxiv.org/content/10.1...

There are now flash talks... I will try to keep up. First is Hannah Li talking about atherosclerosis. WES of carotid-intima media thickness min/mean/max. 47k participants. Single variant + gene based rare variant testing. Functional admission and fine-mapping. Compared with previous GWAS.

Next is Oyesola Ojewunmi discussing foetal haemoglobin (HbF) persistence in sickle cell disease (SCD). SCD is a disease of haemoglobin, with HbA replaced by HbS, causing sickling of the haemoglobin, deforming the blood cell and causing occlusions in vessels and downstream stroke and other sequelae

📢 Calling UK mental health professionals working with neurodivergent young adults 📢 Please take part in our research on depression in neurodivergent young adults! It involves 1 individual interview and 2 focus groups (all online, £25/hour). Sign-up link: shorturl.at/r3HlO Reposts appreciated 🙏

Back after TOO MUCH COFFEEEE Onto ECR talks. First up is Eyad Elbahtety who will talk about Rare Variants in GWAS. Rare variants are neglected in GWAS because they are hard to measure with sufficient precision given typical sample sizes

Now Geli Ronald will talk about a genome wide association study of age at onset walking. Why study this age? Critical period for environment, rapid onset of developmental milestones and brain changes. Arguably under appreciated in common variant genetics.

Nice short preprint proposing a new method to distinguish second degree relatives: half siblings vs niece/nephew avuncular pairs. Both relationships have genomic kinship of 1/4, but they can be distinguished by multiple signals: 🧵 www.biorxiv.org/content/10.6...

Next is our own Vangelis Vassos talking about the implementation of polygenic scores in psychiatry, and whether we are ready yet

I'm in the London Genetics Network annual meeting. First up is Sanjay Sisodiya, who is talking about genetic complexity in a monogenic epilepsy

After 5 years of data collection, our WARN-D machine learning competition to forecast depression onset is now LIVE! We hope many of you will participate—we have incredibly rich data. If you share a single thing of my lab this year, please make it this competition. eiko-fried.com/warn-d-machi...

🚨NEW PREPRINT ALERT!🚨 Jacob Knyspel investigated the moderating impact of exposure to different traumas on genetic risk for PTSD, using data from @ukbiobank.bsky.social, @gladstudy.bsky.social, @edgiuk.bsky.social and @nihrbioresource.bsky.social 1/3 www.researchsquare.com/article/rs-8...

No, YOU'RE crying on the train into work... xkcd.com/3172/

Join us this evening to celebrate the achievements of our outstanding award winners and enjoy an inspiring talk. #WCPG2025

The PRISMA team had a great time presenting our posters on Precision and Genomic Medicine in Psychiatry at the #WCPG2025 in Cancún! 🌴🧬 It was exciting to share our work, learn from others, and connect with colleagues from around the world. @danielmorenodeluca.bsky.social

A quick thread of some great Purdue representation sharing our amazing science at @ispg.bsky.social annual conference #WCPG2025! 🧬 🧠 🧪 First up: @ktnthompson.bsky.social presented work investigating whether family acceptance & belonging mitigate depression risk 👪

Join Dr. Cathryn Lewis for a deep dive into "Navigating the Genetics of Depression: Academic Integrity, Culture, and Leadership" in the Grand Cenote, first floor, tomorrow morning at 8:30 AM EST. #WCPG2025

🚨 I’ll be joining Psychological Science as an Associate Editor starting next month. People at, or near, my intersection of psych genetics, clinical psych, psychological Epidemiology should consider the journal for your best work! (read the EiCs editorial on the journal policies/goals below)

The Estonian Biobank is an awesome resource (and @klehto.bsky.social is similarly awesome) — a fantastic opportunity to do some great science!

This talk, in combination with the one from @laurahercher.bsky.social and the response from @toddlencz.bsky.social just triggered SO many conversations… many continued into the early hours of today, so many people were discussing at the post- session bar gathering at #WCPG2025 …hooray!

An absolutely fantastic opening plenary for the day by @alexcharney.bsky.social …a masterclass in tenacity, vulnerability and courage. Standing ovation. 🥲 I am so proud of this community’s willingness and ability to have difficult but healthy conversations #WCPG2025

So pleased to participate and present our collaborative work on ADHD symptoms at the fantastic #WCPG2025 in this amazing place!

Curious whether response to psychotherapy in OCD can be predicted using clinical and DNA methylation data? Come see Poster 1️⃣ at #WCPG2025. I’ll be presenting our first machine learning findings!

"Don't miss Dr. Peter Visscher's insightful talk on "Heritable Polygenic Editing and Genomic Medicine: Frontier, Futile or Fiasco?". Join us and learn about the future of genetics. #WCPG2025

NOW HIRING #postdocjobs NIH funding for a #postdoc with interest in complex genetics / computation / analysis #GWAS #rarevariants #polygenicriskscores in multiple research contexts: psychiatric genomics; cognitive genomics; embryo screening... acnp.org/wp-content/u...

Greetings #WCPG2025 from Cancun! If you’re at the meeting and looking for a postdoctoral or research scientist position, come find me at poster M66 tonight!

(1/6) We’re excited to present “Advancing the Understanding of Depression Genetics Through Research on Latin American Genomes” at #WCPG2025! 🌎✨ Mon Oct 20 | 9:45–11:15 AM Blue River 3 – Convention Center, Cancún Led by Drs. @roseannpeterson.bsky.social @nscorralfrias.bsky.social 🧵...

The PGC Suicide Working Group will provide a symposium at #WCPG2025 🇲🇽 covering our latest multi-ancestry GWAS and CNV meta-analyses, sex-specific meta-analyses, and GxEHR analyses. 🥳 @lcstoshio.bsky.social @andreyshabalin.bsky.social @sarahcolbert.bsky.social @caina89.bsky.social

Moooorning everyone! Im excited to see you all later! Yay! It’s our first ever conference in Mexico! Excited for it 🥳 #WCPG2025

The WCPG Education Day is here, and we look forward to a lineup of amazing speakers and fascinating sessions!

🚨 @LAGCPsychGene is thrilled about this year's #WCPG2025 @ISPGnet in Cancun, Mexico! We have an exciting line-up of events, symposiums, talks, and poster presentations from our LAGC membership. See below for more info 👇

LAGC will host one of the Education Days at the #WCPG2025 in Cancún, Mexico! Join us for a full day of sessions on neuropsychiatric genetics — entirely in Spanish!

We will have an exceptional set of Plenary speakers, including LAGC members, covering a wide range of important psychiatric genetics topics. #WCPG2025 @ISPGnet 🔥👇

🚨LAGC Major Depressive Disorder Working Group will be having a symposium at #WCPG2025 @ispg.bsky.social covering GWAS, CNV, GXE, and Epigenetics. Co-Chairs: Nadia Corral-Frias, PhD from Universidad de Sonora 🇲🇽, and Roseann Peterson, PhD from SUNY Downstate.

🔥We will have our Latin American Genomics Consortium Working Group meeting on Monday, 6 PM - 7 PM at Blue River 1, Convention Center, 1st Floor #WCPG2025 @ispg.bsky.social Learn about our exciting work and plans! Any #WCPG2025 attendee is welcome. See you there!

#WCPG2025 @ispg.bsky.social 🧬LAGC Oral Session: Psychiatric Genomics in Latin American Populations. Co-Chairs: Humberto Nicolini  & Henriette Raventos Wed 1 PM - 2:30 PM at Blue River 3, Convention Center, 1st Floor

Mild FOMO at all m'colleagues flying off to Mexico for #WCPG2025. Looks set to be a great meeting — hope to read many exciting missives from the front line!

Important recent discovery from the Coleman Research Group — a new Coleman to study

We're going to see a lot of bullshit in the coming days and weeks about "causes of autism", and most will be based on flawed, over-interpreted observational studies (1/n)

The ABCD Study 6.0 release is finally here! 🧠 Apply for data access here @theabcdstudy.bsky.social www.nbdc-datahub.org

What's going on in psychiatric genetics? The @pgcgenetics.bsky.social have now published our latest progress review in @thelancetpsych.bsky.social, highlighting discovery, and laying out a map for moving forwards! www.thelancet.com/journals/lan...

Fantastic to see Maria Koromina's great work out in @natneuro.nature.com! 1. A deep look at potential "causal" genetic signals in bipolar disorder 2. A systematic exploration of the analytical choices involved in fine-mapping meta-analysis 1/4 www.nature.com/articles/s41...

On the day we were awarded an #ERCAdG from the @erc.europa.eu, I want to highlight this non-science paper I wrote with ‪@deefitzgerald.bsky.social‬ on research culture: wellcomeopenresearch.org/articles/9-341 Why? Because I'm often told we need to chose between excellence and kindness

Excited about our new preprint: 1st successful genome-wide study of >61,000 panic attack and 29,000 panic disorder cases. www.medrxiv.org/content/10.1... We find 17 associations & evidence that peripheral neurons in eye, lungs and heart are involved in panic & other psychiatric disorders 1/n

Very pleased to see this paper out in @nathumbehav.nature.com – a useful approach to understanding the role of genetics in sensitising people to their environments (and a sobering example of the sample sizes needed...!) Fantastic work by lead Elham Assary! 1/2 rdcu.be/eqmvJ

I'm fortunate enough to be a Research Scholar with OurFutureHealth, the UK’s largest health research programme. They are hosting webinars for researchers to share the exciting opportunities this unique resource can offer your research. 1/4

Very pleased to see our paper describing the @ukbiobank.bsky.social second online mental health questionnaire has now been published in @plosone.org! This describes the origin of the resource as well as the data. Fantastic work by Katrina Davis in leading this 👏👏👏 dx.plos.org/10.1371/jour...

📣 Psychological & behavioural considerations for integrating polygenic risk scores for disease into clinical practice www.nature.com/articles/s41... Saskia Sanderson & I wrote a piece assessing the common concern that PRS may have psych/behavioural harms tl;dr 👉 There's little/no evidence for this

A great week for genetics, omics, and precision medicine — many exciting reads 🧬 1⃣ Circadian gene expression regulation by rhythmic genetic variants 🧵[1/8]

Check out our new OCD GWAS (53,660 cases and 2,044,417 controls) in @natgenet.nature.com 🧬🧠 Genetic risk was associated with excitatory neurons in the cortex and hippocampus. There was much genetic overlap with anxiety, depression, and anorexia. Open access: www.nature.com/articles/s41...