A single-cell screening platform accelerates functional genetics in plants - @sattelylab.bsky.social go.nature.com/4n8wzLv

How can a single cell learn without a brain? We explore this in my paper with @wallaceucsf.bsky.social! We discovered that single cells may learn using molecules similar to those that animal brains use to learn, like CaMKII. Cells can also propagate memory states to their progeny!

Preprint alert 🚨 (1/10) 🧵 𝘈𝘶𝘵𝘰𝘱𝘩𝘢𝘨𝘺 𝘪𝘴 𝘢 𝘱𝘢𝘳𝘢𝘥𝘰𝘹 𝘪𝘯 𝘱𝘭𝘢𝘯𝘵 𝘪𝘮𝘮𝘶𝘯𝘪𝘵𝘺: It can promote resistance, susceptibility, or restrict cell death 🤯 So what is its actual role? We show it acts as a spatial organizer of immunity across cell types 🌱🦠 #proteostasis www.biorxiv.org/content/10.6...

Required reading for any student of genetics. A lucid and thoughtful piece on term that is far from unambiguous. I encourage sharing widely.

Spatial organization of plant defense at the infection front https://www.biorxiv.org/content/10.64898/2026.04.01.715938v1

Excited to see our work out in Science today! Using machine learning to identify prokaryotic immune systems www.science.org/doi/10.1126/...

Please check this database😂😂 webofnothing.top you can publish your “dreams” there!!!

We recently had a conversation here about reproducible data analysis pipelines. I put my thoughts into a longer-form article. Whatever you do, it's critical you save and archive your final processed data right before plotting. blog.genesmindsmachines.com/p/creating-r...

Excited to share our lab's new paper in Current Biology featuring MS student Sydney Schultz's work. We show that a polar alga carries large amount of giant viral DNA in its genome, and many of the viral genes respond to stress - with implications for host adaptation. www.cell.com/current-biol...

Targeting redundant gene families: A multiplexed, tissue-specific CRISPR toolbox for Arabidopsis genetic screens

Want to image apoplastic pH in plants? 🔬 Two new papers from our team offer a full workflow plus open access analysis tools. Congrats to @aroessling.bsky.social, Niklas Mayle and @lguerard.bsky.social Nature Protocols: rdcu.be/e7R2E BMC Methods: lnkd.in/dctpWJ3X Happy Imaging!

The lab of @elkebarbez.bsky.social strikes again 👇 Cell wall charge acts as a tunable electrostatic gate controlling iron availability in roots. Really nice work linking extracellular physics with nutrient homeostasis.

In our recent review, we explore how the spliceosome is targeted by effectors from diverse plant-interacting organisms—and how these effectors can serve as powerful molecular probes to uncover the mechanisms of splicing regulation in plants. @geminiteamlab.bsky.social #PlantScience #RNA #Splicing

RNA splicing generates a functionally specialized Rep protein isoform in geminiviruses — enabling timely control of the viral cycle. Strikingly, similar strategies might have evolved in DNA viruses infecting different kingdoms: www.biorxiv.org/content/10.6... Spearheaded by @delphinem-p.bsky.social!

Alternative splicing expands the functional portfolio of a plant virus to control the viral cycle https://www.biorxiv.org/content/10.64898/2026.02.19.706752v1

Cool story from @meristemania.bsky.social lab on growth-defense tradeoff at the shoot apical meristem www.biorxiv.org/content/10.6...

Highly recommended！

Please share! My group at @zmbp-tuebingen.bsky.social is offering a post-doctoral position (4 years). We look for a structural biologist with experience in Cryo-EM/Cryo-ET to investigate the mechanisms of host invasion by pathogenic fungi. Deadline February 28th! uni-tuebingen.de/universitaet...

FBI frame-up of Indiana University postdoc Youhuang Xiang: Anti-China witch-hunt escalates www.wsws.org/en/articles/... I'd heard whispers of these arrests for carrying plasmids and bio materials across borders before, but someone just shared this detailed news report with me. Please be careful.

Who wore it better?

Why I’m genetically engineering a rainbow flower… And how a Russian fairy tale inspired the idea 🧵

What could be better than discussing single-stranded DNA viruses with an international community of experts and a trans-kingdom perspective — at an affordable prize? Doing it in Bahia, Brazil! 🌴🌊☀️ Join us for IS3DV, June 15-19! isdv2026.com

Cell-type-specific gating of gene regulatory modules as a hallmark of early immune responses in Arabidopsis leaves nph.onlinelibrary.wiley.com/doi/10.1111/...

Why are so many plant viruses phloem-restricted? New work from Xueping Zhou’s lab reveals how this tissue tropism is determined in a geminivirus — and why phloem confinement can turn out to be an evolutionary advantage! www.nature.com/articles/s41... 🌱🦠🚷🅿️🛫🌱

Organelles do NOT have a single uniform pH. And if you think they must, because “protons diffuse fast,” this paper is for you. A thread on why that assumption is wrong; and what we found instead. 🧵 1/n

We're looking for a new PhD candidate to join the lab. Please share 🌱😄

1/ Preprint alert:
 🌾 The developing leaf of the wild grass Brachypodium distachyon at single-cell resolution
 👉 doi.org/10.1101/2025... A 70k-cell single-cell RNA-seq atlas of the developing grass leaf—from the shoot meristem to mature leaf tissues. @cerealcell.bsky.social @lbmountain.bsky.social

Out in @science.org this week: PME5 is sequestered in the nucleus and released during cytokinesis allowing its activity to be timed with cell division. www.science.org/doi/10.1126/... #PlantScience #PlantSci

"Leaf It to Science: Uncovering Plant Immune Systems Through Technological Advances Open Access" Reflections on Career, #PlantScience and #PlantImmunity by Xinnian Dong academic.oup.com/plphys/advan...

when it started…😎😉❤️🔥

Rosa Lozano-Durán (@geminiteamlab.bsky.social), one of the newly elected EMBO members 2025, has introduced her research at the @embo.org Members' Meeting in Heidelberg. We are so proud of you! #plantsci

1/10 Genome maintenance by telomerase is a fundamental process in nearly all eukaryotes. But where does it come from? Today, we report the discovery of telomerase homologs in a family of antiviral RTs, revealing an unexpected evolutionary origin in bacteria. www.biorxiv.org/content/10.1...

FRET sensor for SA developed. www.science.org/doi/10.1126/...

A long road to the Cover of Science! www.science.org/doi/10.1126/...

Sad news 😔 R.I.P. Jane Goodall! lived an inspiring life & made the world a better place www.theguardian.com/science/2025...

Check out this new story from the Felix lab, with some contribution from us: Receptor antagonist prevents hyperactivation of the plant immune system www.sciencedirect.com/science/arti...

From a gene’s single cell expression–through spatial localization–to novel function, and beyond! Now out @natplants.nature.com We built a comprehensive spatial-transcriptomic atlas of Arabidopsis, revealing cell-type identities across organs in unprecedented detail www.nature.com/articles/s41...

A root-based N-hydroxypipecolic acid standby circuit to direct immunity and growth of Arabidopsis shoots www.nature.com/articles/s41...

My first MPMI #2025ISMPMI 😎😍@GeminiTeam Excited to hear all the amazing science, have great discussions, and connect with friends! If you’re interested in plant-(Gemini)virus interactions and scRNA-seq, let’s meet on Wednesday, July 16 at poster P-437. #scRNA-seq (bring me to your poster as well!

Have you ever wondered why virus-infected plants twist, curl, yellow, and/or stop growing? We did—you can read what we found in our latest review: www.annualreviews.org/content/jour... @gmvalora.bsky.social @annualreviews.bsky.social

This is textbook cell biology material by chin-hang Wu and colleagues . Check it out 👇 #plantsci #plantpath #immunology #NLRbiology www.biorxiv.org/content/10.1...

#JustIn on Plantae: How to Manage Your Time Effectively as a Researcher. In this new piece, ASPB Plantae Fellows Gourav Arora, Elisa De Meo and Ved Prakash explore practical time management strategies tailored to the unique challenges of academic research. buff.ly/nYo0K4m #plantscience

How plants sense injury in their barrier tissue, periderm? Painstakingly detailed and amazing work by post doc Hiroyuki Iida shows that wounding is sensed by the diffusion of two gases: ethylene and oxygen. @treebiocoe.bsky.social‬ @erc.europa.eu‬ 1/x 🧵 www.nature.com/articles/s41...

Broad application of the ALFA tagging technology for in planta nanobody-based imaging and biochemical characterization of plant proteins #resource #PlantCommunications cell.com/plant-commun...

Explore your beloved viruses😎🤩

Congratulations to Jeff Dangl, Jonathan Jones & Brian Staskawicz, winners of the 2025 Wolf Prize in Agriculture! Well done, my friends! www.youtube.com/live/gU8VBaR...

In our last work that is just out in @newphyt.bsky.social we use a transcription inhibitor to improve the detection of mild drought stress responses in scRNA-seq. Browsable dataset on www.single-cell.be/plant/leaf-drought . Thanks to Ruben Tenorio Berrio and collaborators for the exciting collab!

Paradigm shifting work from the Friml lab - degradation of auxin response repressors is not causal for the transcriptional reprogramming, cAMP signaling is - awesome read! www.nature.com/articles/s41...

#plantsci #loveplant #happyplant #poorplant