Two amazing weeks of science and new friendships! 🧠🔬Hope to cross paths again someday! Huge thanks to everyone behind the 2025 Q2 Summer School @ibroorg.bsky.social

Post-weaning social isolation impairs dendritic spine plasticity in the rat hippocampus @sfn.org Session Name: Early Life Stress Session Number: PSTR400 Session Date & Time: Wednesday, November 19, 2025, 8:00-12:00 h #NeuroTwitter #SfN25 #SciTwiitter #AcademicTwitter

New article in Neuroscience @ibroorg.bsky.social! Special for 2 reasons: the 1st paper of my colleague Yali (1st author) and my first as Cinvestav researcher. 🧠🐭Peer play fosters healthy brain development, while social isolation alters prefrontal connectivity. www.sciencedirect.com/science/arti...

Distribution and morphological features of astrocytes and Purkinje cells in the human cerebellum | Frontiers in Neuroanatomy www.frontiersin.org/journals/neu...

Excited to have given my first seminar as a PI at Cinvestav! Grateful to the Department of Physiology, Biophysics, and Neurosciences for the kind invitation and the opportunity to share my research. Looking forward to future collaborations! #OrgulloCinvestav

"Should we really set time and space apart for things that distract us from our jobs? Yes we should, because many of the breakthroughs in science were made by people who were distracted" The forgotten half of scientific thinking | @pnas.org www.pnas.org/doi/10.1073/...

Check out this ✨brand new✨ review out now from @ayakokk.bsky.social & team 🤩

A postnatal molecular switch drives activity-dependent maturation of parvalbumin interneurons in mice | @cellpress.bsky.social www.cell.com/cell/fulltex...

🚨 New @npp-journal.bsky.social paper alert 🚨 👇

Early-life adversity alters adult nucleus incertus neurons in mice: implications for neuronal mechanisms of increased stress and compulsive behavior vulnerability | @npp-journal.bsky.social www.nature.com/articles/s41...

A nice comment, recognizing the significant contributions of @neurorights.bsky.social, while highlighting the long road ahead at the legal level for the neurorights. Challenges of the inconsistent neurorights framework in Latin America | @natneuro.nature.com www.nature.com/articles/s41...

Two suicide ideation routes described: 1) internalizing symptoms starting in adolescence w/o prior issues 2) early adulthood onset linked to chronic childhood symptoms Early, developmentally timed mental health care is crucial for prevention | @jama.com jamanetwork.com/journals/jam...

Functional vs Structural Cortical Deficit Pattern Biomarkers for Major Depressive Disorder | @jama.com jamanetwork.com/journals/jam...

Pharmacological reduction of reverse-translated hippocampal hyperactivity in mouse: relevance for psychosis | @npp-journal.bsky.social www.nature.com/articles/s41...

Individuals with first-episode psychosis already show elevated cardiovascular biomarkers, even before traditional risk indicators like body mass index (BMI) or blood glucose levels change. Early detection is essential | Schizophrenia www.nature.com/articles/s41...

Adapt-A-Maze: An Open Source Adaptable and Automated Rodent Behavior Maze System | eNeuro @sfnjournals.bsky.social www.eneuro.org/content/earl...

Sequential decreases in basolateral amygdala response to threat predict failure to recover from posttraumautic stress disorder (PTSD) | @npp-journal.bsky.social www.nature.com/articles/s41...

Sex and regional differences in striatal gene expression in psychosis: a postmortem study of human brain samples www.nature.com/articles/s41...

2nd paper of the week published! 🔥🔥 DTG reduces immobility from day one and only causes catalepsy after prolonged use. It acts on sigma-1 and D2 receptors, highlighting the need for further studies on sigma-1 mechanisms in psychosis treatment 🐭🧠💊📈 www.sciencedirect.com/science/arti...

Publication alert!🚨📄Chronic sleep loss increased alcohol preference in rats. Combined with alcohol, it altered PFC structure—no synergistic effect, but changes may drive addictive behaviors. Sleep loss could raise addiction risk 🐀💤🍺🧠 www.sciencedirect.com/science/arti...

🚨Hot off the press! Alcohol use disorder (AUD) induces inflammation in the left cerebellar posterior lobe, evidenced by increased astrogliosis and T-cell infiltration. Here our latest research article: onlinelibrary.wiley.com/doi/abs/10.1...

AMPA receptors were thought to play a limited role in memory and learning due to calcium impermeability. New findings show some subtypes do allow calcium flow, reshaping our understanding of neural transmission | @nature.com www.nature.com/articles/s41...

Maternal inflammatory proteins VEGFA, CCL2, CD5, IL-12B, FGF-23, and MCP-1 during pregnancy are associated with an increased risk of neurodevelopmental disorders at childhood | @jama.com jamanetwork.com/journals/jam...

#brainawarenessweek2025 🧠 🐭

New work from the lab published at @cp-neuron.bsky.social. In this study we dissect the role of hormonal regulation in pain-induced enhanced opioid intake in males. Work conducted by the super talented @jessinbotham www.cell.com/neuron/fullt...

Chemogenetic activation of microglial Gi-GPCR signaling decreases microglial surveillance and impairs neuronal synchronization in mice | @science.org www.science.org/doi/10.1126/...

Aging disrupts the coordination between mRNA and protein expression in the mouse and human midbrain, with a focus on dopaminergic pathways www.nature.com/articles/s41...

In early psychosis and associated risk states, synaptic density reductions are observable. Additionally, cannabis use lowers synaptic vesicle glycoprotein 2A (SV2A), which could serve as a biological target for better understanding negative symptoms | @jama.com jamanetwork.com/journals/jam...

Molecular and cellular dynamics of the developing human neocortex www.nature.com/articles/s41...

Fabulous work from my undergrad friends, working in #Mexico ( #UNAM and #CINVESTAV). Check it out: www.science.org/doi/full/10....

Ketamine administration during adolescence impairs synaptic integration and inhibitory synaptic transmission in the adult dentate gyrus of mice www.sciencedirect.com/science/arti...

Neocortical somatostatin neuron diversity in cognition and learning: doi.org/10.1016/j.ti... "In this review, we discuss and synthesize recent advances in understanding the diversity, circuit integration, and functional properties of this important group of GABAergic neurons."

Stayed connected with SfN on BlueSky! 🧠 Follow @sfn.org for SfN news & updates, @brainfactsorg.bsky.social for neuroscience education, @sfnjournals.bsky.social for the latest research from JNeurosci & eNeuro, and @neuronline.sfn.org for career resources & community discussions. #Neurosky

Astrocytes Mediate Psychostimulant-Induced Alterations of Spike-Timing Dependent Synaptic Plasticity in Mice onlinelibrary.wiley.com/doi/10.1002/...

Physiological and molecular impairment of PV circuit homeostasis in mouse models of autism https://www.biorxiv.org/content/10.1101/2025.01.08.632056v1

Typical development of synaptic and neuronal properties can proceed without microglia in the cortex and thalamus in 🐭 www.nature.com/articles/s41...

The Adolescent Brain Cognitive Development Study and How We Think About Addiction jamanetwork.com/journals/jam...

We just published a thing! In this study, we provide compelling evidence that a lack of microglia during early brain development does not lead to wholesale alterations of synaptic and cellular function. www.nature.com/articles/s41...

A spatial threshold for astrocyte calcium surge, in mice @elife.bsky.social doi.org/10.7554/eLif...

Heroes of the Engram 🧠| @sfnjournals.bsky.social www.jneurosci.org/content/37/1...

Intestinal permeability biomarkers in patients with schizophrenia: Additional support for the impact of lifestyle habits www.cambridge.org/core/journal...

🚨 New article published! We explore the role of the amygdala in the pathophysiology of mental illnesses 🧠 Full text: www.sciencedirect.com/science/arti...

Striatal Astrocytes Influence Dopamine Dynamics and Behavioral State Transitions https://www.biorxiv.org/content/10.1101/2024.12.01.626240v1

Our paper is out just in time for #EM_Monday! It is about a specialized neuron-specific ER, called the spine apparatus, which is found close to synapses and has a very peculiar shape. If you think neurons are special, the spine apparatus is their🦄 horn! But how does it form?! doi.org/10.1016/j.cu...

Striatal interneuron imbalance in a valproic acid-induced model of autism in rodents is accompanied by atypical somatosensory processing | @societyforneuro.bsky.social journal eNeuro www.eneuro.org/content/earl...

More evidence linking gut & mental health. Adolescents with early-onset psychosis show distinct gut microbiome changes. Antipsychotics and antidepressants also impact microbial profiles, affecting fatty acid metabolism pathways 🧠💩🧬 www.mdpi.com/2076-2607/12...

Your friends shape your microbiome — and so do their friends 🫂🦠🧠 | @Nature www.nature.com/articles/d41...

🚨New paper alert! Insights into neuroplasticity in schizophrenia. Spine impairments in density & shape in temporal cortices in rats with neonatal ventral hippocampus lesion (NVHL) are attenuated by antipsychotics, highlighting neuroplasticity’s role in therapy 🐭🧠🔬 doi.org/10.1016/j.bb...