Please join us on Nov 20 for a webinar on improving antibiotic spectrum choice for adults and kids! We're happy to be joined by Drs @tttimbrook.bsky.social, Chanu Rhee, and Jeffrey Gerber for a discussion moderated by @cidrap.bsky.social's Dr Marnie Peterson www.cidrap.umn.edu/antimicrobia...

"I'm still in shock. I know that there have been political issues around Harvard in recent weeks, but antibiotic resistance isn't one of them." My conversation with Harvard microbiologist @baym.lol, one of many researchers there who just lost millions in fed. grants. www.wbur.org/news/2025/05...

#SNAP PSSA silo results #escmidglobal Should we be using Benzylpenicillin all the time? Looks superior and has less AKI

One of our wonderful medical students has categorized what itraconazole side effects look like in a modern cohort. It turns out, Itraconazole is better tolerated long-term than Fluconazole, based on earlier work. Side effects associated with itraconazole therapy academic.oup.com/jac/article-...

𝐌𝐚𝐤𝐞 𝐲𝐨𝐮𝐫 𝐜𝐥𝐢𝐧𝐢𝐜𝐚𝐥 𝐩𝐫𝐞𝐝𝐢𝐜𝐭𝐢𝐨𝐧 𝐫𝐞𝐬𝐞𝐚𝐫𝐜𝐡 𝐦𝐚𝐭𝐭𝐞𝐫! Scoping review on rpredictor and outcome variables for 𝐦𝐨𝐫𝐭𝐚𝐥𝐢𝐭𝐲 𝐦𝐨𝐝𝐞𝐥𝐬 𝐫𝐞𝐟𝐥𝐞𝐜𝐭𝐢𝐧𝐠 𝐭𝐢𝐦𝐢𝐧𝐠 𝐚𝐧𝐝 𝐦𝐞𝐭𝐡𝐨𝐝𝐬 𝐨𝐟 𝐦𝐞𝐚𝐬𝐮𝐫𝐞𝐦𝐞𝐧𝐭 𝐰𝐞𝐫𝐞𝐧'𝐭 𝐫𝐞𝐩𝐨𝐫𝐭𝐞𝐝 𝐢𝐧 𝐚𝐬 𝐡𝐢𝐠𝐡 𝐚𝐬 68% 𝐨𝐟 𝐭𝐡𝐞 𝐭𝐢𝐦𝐞. Critical for external validations and use. www.sciencedirect.com/science/arti...

Nice review of an antibiotic -- pivmecillinam -- that's been available in other countries for many years, and soon *should* be available here. Anyone have any experience with it? What's holding up availability? #IDSky doi.org/10.1093/cid/...

"Reasons for choosing rezafungin over daily echinocandins were...cost effectiveness compared with the cost of daily caspofungin administration by the OPAT nurses." 💡https://academic.oup.com/jacamr/article/7/Supplement_1/dlae217.004/7976576

Excellent read from Debra Goff on her impactful, long, and continuing career in antimicrobial stewardship as well as examining the challenges in this profession towards it's sustainability www.cambridge.org/core/journal...

Hernan et al expand on why the proportional hazards assumption is both implausible and unnecessary in most medical studies, particularly in RCTs. They conclude that using survival analysis methods that do not rely on PH is typically the preferred course of action academic.oup.com/aje/advance-...

Kudos to Lanford, Daneman, and colleagues on the use of modern epi approaches (e.g. IV analysis) for such practical and timely questions 👏👏👏

how would you treat and ICD infection with lead and valvular vegetation that grew Staph aureus mecA gene positive per Biofire but Oxacillin susceptible per routine blood culture? Would you treat as MSSA with cefazolin or as MRSA with Vanco or Dapto ?

#AMR is a risk to antibiotic failure & death, but if this happens, do we record it on death certificates? Our centre data = NO! 👉In 1 year, 4% of deaths were AMR-attributed & NONE were recorded on death certificates!👈 Need to quantify this better to increase awareness! #IDSky @jac-amr.bsky.social

Antimicrobial resistance (AMR) is a major threat to human health. Bur it's GROSSLY under reported This study showed 4% of ALL deaths at a major London hospital were actually caused AMR but NONE were on the death certificate as cause of death.

𝐂𝐚𝐧 𝐆𝐞𝐧𝐨𝐭𝐲𝐩𝐢𝐜 𝐀𝐌𝐑 𝐆𝐮𝐢𝐝𝐞 𝐃𝐞-𝐞𝐬𝐜𝐚𝐥𝐚𝐭𝐢𝐨𝐧 𝐢𝐧 GN-BSI? Our meta in CMI (74 studies, 24590 samples) finds mol tests for BSI have 92–99% sens & 99–100% spec for ID. AMR: 91–99% & 99–100%. P𝐞𝐫𝐟𝐨𝐫𝐦𝐚𝐧𝐜𝐞 𝐟𝐨𝐫 𝐀𝐌𝐑 𝐰𝐚𝐬 𝐠𝐞𝐧𝐞𝐫𝐚𝐥𝐥𝐲 𝐜𝐨𝐧𝐬𝐢𝐬𝐭𝐞𝐧𝐭 𝐚𝐜𝐫𝐨𝐬𝐬 𝐫𝐞𝐠𝐢𝐨𝐧𝐬 www.clinicalmicrobiologyandinfection.com/article/S119...

UPMC & Pitt are looking for a Medical Director, System Antimicrobial Stewardship! This person will partner with Dr. Graham Snyder, Tina Khadem, & myself to lead 37 US-based hospitals' antimicrobial stewardship and infectious diseases quality efforts. #idsky #medsky cfopitt.taleo.net/careersectio...

🚨 ID PharmDs looking to join the BILH family, we've got 2 Stewie positions available at some of our community hospitals: 🚨 Needham jobs.bilh.org/job/needham/... MAH jobs.bilh.org/job/cambridg...

I read the first post in this thread about mirror life, thought “they can’t mean…”, and then clicked the link. Yep, that’s exactly what they mean. Bioengineering reversed-chirality microbes. Vaughn’s piece is a necessary if frightening read.

Using climate information may help in empiric antibiotic selection when treating patients with diabetic foot infection. #IDSky academic.oup.com/ofid/article...

Good read. Reviews opportunities and importance on combining RVP with host markers, need and potential clinical impact of semiquant of viruses, unmet needs on specific viral etiology detections in commercial assays. In contrast to Betteridge's law, I think the answer here is yes.

👀 New in @AJHPOfficial! academic.oup.com/ajhp/advance... “You do not currently have access to this article.” as usual. 🤑 #IDsky

Here is a nice pre/post cohort study reporting the Stanford Ortho ID group’s experience implementing routine PO switch. They achieved a 45% increase in discharge on PO abx with no diff in 90d clinical outcomes, shorter LOS, and trend toward fewer IV-related AEs: pubmed.ncbi.nlm.nih.gov/39660026/

🆕✨Systematic literature review and meta-analysis @cmijournal.bsky.social Performance of molecular tests for diagnosis of bloodstream infections in the clinical setting With 🌟s @tttimbrook.bsky.social #idsky #medsky #microsky #EMIMCC www.clinicalmicrobiologyandinfection.com/article/S119...

A powerful piece by @melodyschreiber.com. My heart goes out to you. This line broke me: "Then I cried, because that was not a thought that should ever enter a parent’s mind at a time like this – can we afford to save him? – and yet it did." www.theguardian.com/commentisfre...

Another RCT showing PCT helps. Getting close to 30 of these. And that’s the difference between it and CRP. The former has RCT support. The latter doesn’t.

New research article in The Lancet Microbe Bacteriology testing and antimicrobial resistance detection capacity of national tiered laboratory networks in sub-Saharan Africa: an analysis from 14 countries www.thelancet.com/journals/lan... #IDSky #ClinMicro #AMR #OpenAccess #OA

Hello Bluesky! We’re Applied Epi! What do we want? To improve Applied Epidemiology worldwide! When do we want it? Well probably in an achievable timeframe that doesn’t completely destroy a much needed and already existing infrastructure that is overburdened!

👀⤵️ - @altmetric.com further cementing Bluesky as a platform for sharing and quantifying academic discussions. ⭐ And, as this thread demonstrates, it's been achieved with a good dose of humour, which never goes amiss in life or academia! 👏 #AcademicSky #IDSky #ImmunoSky #clinmicro

Dear #IDSky, you guys are absolutely killing it!!! Let’s keep going! #Meal-ioidosis #HCWvsHunger @jabarocas.bsky.social HCWvsHunger.org

Good explainer of how #HCWvsHunger works Donate to a food bank of your choice Go to HCWvsHunger.org to log the donation; pick a team for the amount to be tallied under (go #Meal-ioidosis!) Cheer your team & encourage your friends (peer pressure but for good!) We all win! #MedSky #IDSky

Core Elements of Hospital Diagnostic Excellence (DxEx) | Patient Safety | CDC www.cdc.gov/patient-safe...

COpAT 😊✊

I’m thinking we need a #clinmicro feed and starter pack for those focused on ID diagnostics and clinical microbiology (like me!). ID Dx /clin micro colleagues, I’m looking for you! #IDsky #microsky #micro #infectiousdiseases

The Journal of Clinical Epidemiology is, as of today, present at Bluesky 🎉 And, only here, you can have a sneak preview of our new journal and website design. But of course, our contents remains key, with many thanks to our authors, reviewers, editorial board and editorial team