This 18-year study shows the increasing trend of ESBL E. coli in blood stream infections in Laos. These results have implications for treatment guidelines doi.org/10.1093/jaca... #JACAMRNews #IDSky

Detecting minor resistance-associated variants in tuberculosis WGS samples improves the sensitivity of rifampicin resistance prediction: doi.org/10.1093/jaca... @philipwfowler.bsky.social @vbrunner.bsky.social #JACAMRNews #IDSky

“More people than ever are acquiring infections that cannot be effectively treated by #antibiotics.” New English surveillance programme for antimicrobial utilisation and resistance (ESPAUR) report finds that deaths linked to antibiotic-resistant #superbugs rose 17% in England in 2024.

“Diverse patterns of isavuconazole use were observed in a large cohort of critically ill adult patients, and the drug was well tolerated” doi.org/10.1093/jaca... #JACAMRNews #IDSky

Penicillin allergy de-labelling needs to be a core part of healthcare workers’ roles for it to be prioritized: doi.org/10.1093/jaca... #JACAMRNews #IDSky

In VREfm BSIs where most patients received daptomycin >10 mg/kg, dose was associated with microbiological failure, but not mortality Daptomycin was well tolerated: doi.org/10.1093/jaca... #JACAMRNews #IDSky

Promote responsible antimicrobial compliance in Vietnam to combat antimicrobial resistance and ensure effective treatments: doi.org/10.1093/jaca... #JACAMRNews #IDSky

Reflexive thematic analysis, guided by the COM-B model, explored how Irish parents navigate antibiotic use for children’s RTIs Emotional, behavioural & structural factors shape decisions, highlighting the need for trust-based, context-sensitive AMR interventions:

MDR ESBL-producing Enterobacterales were identified from Parirenyatwa Hospital wastewater So MDR ESBL-producing bacteria may end up being discharged together with municipal wastewater into Lake Chivero where domestic water is pumped from doi.org/10.1093/jaca... #JACAMRNews #IDSky

Treatment durations of 4 weeks or shorter may be adequate for patients with MSSA native tricuspid valve endocarditis without metastatic infectious complications: doi.org/10.1093/jaca... #JACAMRNews #IDSky

Chan et al. assessed the safety and complications of outpatient cefazolin elastomeric infuser via a peripheral intravenous catheter doi.org/10.1093/jaca... #JACAMRNews #IDSky

LEAP develops AMS leaders beyond infection specialties—embedding stewardship into routine care and decentralising leadership across the NHS doi.org/10.1093/jaca... @bsacandjac.bsky.social #JACAMRNews #IDSky

As the centenary of Fleming's discovery of penicillin approaches, drug-resistant infections increasingly impact those with least resource Sustained action to safeguard antibiotics globally is needed including renewed commitment & leadership from the UK doi.org/10.1093/jaca... @raseaton66.bsky.social

A new special Supplement in the Journal of Antimicrobial Chemotherapy celebrates 20 years of the BSAC Antimicrobial Resistance Surveillance Project. Its remarkable legacy and rich archive will continue to guide research and inspire future surveillance efforts around the world. 👏👏👏

This is the first report in Italy of the results of in-depth genomic characterization using a hybrid assembly approach of two NDM-5-producing E. coli, isolated in 2021 and 2023 from the caecal content of veal calves from two different holdings doi.org/10.1093/jaca... #JACAMRNews #IDSky

This monocentric observational study of 137 patients with bone & joint infection treated by clindamycin of which 88 received monotherapy shows in univariate, multivariate & IPTW analysis a reliable & safe use of monotherapy in those infections: doi.org/10.1093/jaca... #JACAMRNews #IDSky

Patients suffering from recurrent C. difficile infection in Sweden described their perceptions about the cause of their disease: antibiotics They also described a scarce information process in a healthcare system without proper resources doi.org/10.1093/jaca... #JACAMRNews #IDSky

Nasomsong et al. conducted an observational study to evaluate the efficacy of high-dose tigecycline for carbapenem-resistant Enterobacterales bacteraemia: it was associated with improved microbiological clearance & showed a trend toward reduced mortality doi.org/10.1093/jaca... #IDSky

Predominance of ST772 ‘Bengal Bay’ MRSA causing human infections in Nigeria Enhanced genomic surveillance and coordinated intervention strategies in LMICs are essential to address the growing threat of MRSA and its impact on public health doi.org/10.1093/jaca... #JACAMRNews #IDSky

Mori et al. found substantial knowledge gaps among non-infectious diseases physicians regarding bacterial bloodstream infection management: doi.org/10.1093/jaca... #JACAMRNews #IDSky @bsacandjac.bsky.social

This systematic review highlights gaps in health and social care professionals’ knowledge, attitudes, and practices on infection management, antimicrobial use and stewardship, emphasizing the need for targeted interventions: doi.org/10.1093/jaca... #JACAMRNews #IDSky

Wong et al. report prevalence of MG infection and resistance in MSM with HIV: doi.org/10.1093/jaca...: #JACAMRNews #IDSky

ESCMID’s 2-year Antimicrobial Stewardship (AMS) Certificate Program works! 65% of participants performed a project with real-world impact in #AntimicrobialStewardship: doi.org/10.1093/jaca... #JACAMRNews #IDSky

A literature search identified 7 published resources on AMS undergraduate healthcare professional curricula or competency frameworks (CF) & compared with the WHO CF Domains varied but significant overlap in WHO competencies in all 7 doi.org/10.1093/jaca... #IDSky @bsacandjac.bsky.social

Free NHS eLearning with BSAC: Optimising the Blood Culture Pathway. Practical, role-specific training to improve outcomes, speed diagnosis & support antimicrobial stewardship. Start learning today. infectionlearninghub.co.uk/blood-cultur...

Is there scope for #AntimicrobialStewardship interventions in community pharmacy? Read on to explore where we are at and where we can go! doi.org/10.1093/jaca... #JACAMRNews #IDSky

Pharmacists’ access to clinical data and collaboration with healthcare providers are crucial steps to improve #AntimicrobialStewardship implementation in community settings doi.org/10.1093/jaca... #JACAMRNews #IDSky

📝 Call for abstracts is open for #ACC2026! Researchers are invited to share their work on #AMR for short talks or poster presentations. 💡 Themes: child & maternal health, stewardship & access, clinical research, AI in health & more. ⏳ Deadline: 14 Nov 2025, 17:00 GMT 🔗 acc-conference.com#posters

This study shows that more isolates of Escherichia coli, Klebsiella pneumoniae and other Enterobacterales are susceptible to amoxicillin/clavulanate than ampicillin/sulbactam: doi.org/10.1093/jaca... #JACAMRNews #IDSky

Social determinants of health impact the risk of antimicrobial resistance It’s time to refocus the research lens for knowledge, attitude and practice studies in AMR and prioritize change to address the upstream determinants: doi.org/10.1093/jaca... #JACAMRNews #IDSky

Interdisciplinary approach to blood culture result management linked to decrease in mortality in community-onset S. aureus infections: doi.org/10.1093/jaca... @kasic.bsky.social #JACAMRNews #IDSky

Eravacycline: a further weapon against NDM-producing Klebsiella pneumoniae? The case of a man with surgical site infection successfully treated with eravacycline plus ceftazidime/avibactam plus aztreonam doi.org/10.1093/jaca... #JACAMRNews #IDSky #AMRrounds @wwrighid.bsky.social

Check out this new #SAFEAMR study published in @jac-amr.bsky.social, which examines how antimicrobial resistance #AMR is framed in global policy, and the importance of clear, targeted messaging to drive action across all sectors. 📎 Publication: bit.ly/42ekH0Z

Study of differences in the intestinal microbiome & resistome among high-risk patients who are & are not colonized with CRE found statistically significant changes in the resistome Longitudinally shifts were associated with antibiotic exposure doi.org/10.1093/jaca... #JACAMRNews #IDSky

Prolonged IV antibiotics aren’t just a patient safety issue - they generate considerable CO₂e #AMS is climate action doi.org/10.1093/jaca... #JACAMRNews #Stewardship #Sustainability #IDSky @saiedali.bsky.social

This single-centre, prospective, observational pharmacokinetic study showed administering 3 g of ampicillin/sulbactam every 3 h maintained sufficient plasma concentration among adult liver transplant recipients even with excessive bleeding: doi.org/10.1093/jaca... #JACAMRNews #IDSky

What is the optimal teicoplanin target for E. faecium bacteraemia? Yamaguchi et al. found a freeAUC24/MICEtest of ≥462 reduces treatment failure: doi.org/10.1093/jaca... #JACAMRNews #IDSky #AMR #PKPD

Infection with antimicrobial-resistant organisms significantly worsens outcomes in cancer patients A survey of oncologists offers data that could support the development of oncology-specific AMS strategies and training programs: doi.org/10.1093/jaca... #IDSky #JACAMRNews

First-in-human study of the bezothiazinone and DpRE1 inhibitor, BTZ-043, a novel anti-TB drug candidate Single ascending doses of BTZ-043 administered to healthy participants showed a good safety profile and favourable PK properties: doi.org/10.1093/jaca... #JACAMRNews #IDSky

Fluoroquinolone use in France dropped over the past decade amid efforts to curb resistance and side effects, but continued efforts are needed to promote safe use: doi.org/10.1093/jaca... #JACAMRNews #IDSky #AntibioticStewardship #Fluoroquinolones #DrugUtilisation #France

Meštrović et al. present a comprehensive set of pre-COVID-19 AMR burden estimates (deaths & DALYs) for Germany for 23 bacterial pathogens & 88 pathogen-drug combinations, and pursue comparative analysis with previous estimates doi.org/10.1093/jaca... #JACAMRNews #IDSky

This paper explores patients’ views of their experiences of penicillin allergy de-labelling. Their insights will be used to further optimize penicillin allergy de-labelling implementation interventions: doi.org/10.1093/jaca... #JACAMRNews #IDSky

New research by @evakrockow.bsky.social et al. finds #AMR messages too technical and unclear We need clearer, more relatable comms to drive change: doi.org/10.1093/jaca... @evakrockow.bsky.social @bsacandjac.bsky.social #JACAMRNews #IDSky

FI-Lab is a predictor of mortality in CDI patients and a valuable tool for early risk stratification: doi.org/10.1093/jaca... #JACAMRNews #IDSky

Genomic and phenotypic analysis reveals high antimicrobial resistance in A. baumannii from combat wounds in Ukraine, posing treatment challenges: doi.org/10.1093/jaca... #JACAMRNews #IDSky @bsacandjac.bsky.social

Genome report of MDR and ESBL-producing Shigella flexneri from Japan highlights antimicrobial resistance and virulence genes: doi.org/10.1093/jaca... #JACAMRNews #IDSky

In vivo emergence of ceftazidime/avibactam resistance in an OXA-244-positive E. coli strain, driven by a YRIK insertion in PBP3 & mutations in the AcrB efflux pump & PBP2—a multifaceted resistance mechanism beyond β-lactamase activity: doi.org/10.1093/jaca... #JACAMRNews #IDSky

Phage vB_AbaSt_W16 shows potent efficacy and favourable PK/PD profiles against CRAB infections in mice, supporting its clinical potential: doi.org/10.1093/jaca... #JACAMRNews #IDSky

During the 2023 epidemic in China, M. pneumoniae isolates were highly resistant to macrolides but susceptible to tetracycline & quinolones To treat macrolide-resistant M. pneumoniae, tetracycline, moxifloxacin & doxycycline would be the recommended antibiotics doi.org/10.1093/jaca... #JACAMRNews

HCV Genotype 5 & 34 Genotype 2 unclassified subtypes reported in Cameroon: no resistance mutations to NS5B polymerase inhibitor sofosbuvir—evidence that sofosbuvir-containing regimens are effective for 1st line hepatitis C treatment in Cameroon doi.org/10.1093/jaca... #JACAMRNews #IDSky