MDPRC retreat 2025

"The interoceptive origin of reinforcement learning" http://dlvr.it/TPHbz0 Frederike H. Petzschner, @danasmall.bsky.social & colleagues @cp-trendscognsci.bsky.social #SfN2025

Is overeating driven by hedonism? @danasmall.bsky.social &co argue that the pleasure of eating food is not a driver of the #obesity epidemic, but rather the regular consumption of an unhealthy diet blunts sensitivity to interoceptive signals that drive food reward #neurosky 🧪 plos.io/4nTlHQc

Amid lots of uncertainty, anger, and exhaustion I am excited to share this work from my incredibly talented MSTP and @nuincomm.bsky.social student Haley Province. In it we explore the fascinating and powerful anti-aversive properties of GIPR agonists

The GLP-1RA/GIP agonist tirzepatide increased risk of early worsening of diabetic #retinopathy in #T2D, similar to effects of GLP-1RA treatment but conversely had a protective effect against new retinal complications in those without retinopathy link.springer.com/article/10.1... 🔓

One third of kids 12-17 in the US have pre-diabetes. gis.cdc.gov/grasp/diabet...

Double-blind placebo controlled trial (led by UAB faculty Dr. Timothy Garvey) demonstrates >20% weight loss with co-administration of cagrilintide (which targets amylin receptors) with semaglutide (which targets GLP-1 receptors). www.nejm.org/doi/full/10....

I think Mark is onto something with this one. Totally agree that there is something wrong with onions. open.substack.com/pub/markscha...

Nothing beats the feeling when your research gets picked up by the media! 🎉 Our latest study is featured on NRK – so great to see science reaching a wider audience. 🔬📰 #ScienceCommunication #NRK www.nrk.no/trondelag/kj...

For the past couple of years I met weekly with 3 amazing younger scientists @lilweb.bsky.social @debyee.bsky.social @rikepetzschner.bsky.social to share ideas and teach each other. No agenda. It was often the favorite part of my week. Then we started writing. www.sciencedirect.com/science/arti...

#ResearchRewind: "Habitual daily intake of a sweet and fatty snack modulates reward processing in humans" http://dlvr.it/TKpXYF @cp-cellmetabolism.bsky.social @danasmall.bsky.social

A drop of milkshake takes a wild ride as it passes through the body. Rachel and Kiersten and the team came up with cool strategies for visualizing food passing through the mouse GI tract and mapping the activity of the same 100s of brainstem neurons across weeks during feeding and other behaviors.

open.substack.com/pub/markscha.... As a former president of the society for the Study of Ingestive Behavior @ssib, I recommend this great read describing what we are up against

Join us for the next edition of Neurogenesis on March 26 at @theneuro.bsky.social, featuring @danasmall.bsky.social & @yasharneuro.bsky.social! Learn about their research on gut-brain connections and the aging brain & network with peers at the post-event reception.🧠 Register now: mcgill.ca/x/iw5

🚨📃New Wassum Lab Paper📃🚨 Out today, @jackiegio.bsky.social discovered brain pathways that support agency and habit and how chronic stress disrupts them to rob of us our agency and cause us to form rigid habits 🧵👇 www.nature.com/articles/s41... Free full text: rdcu.be/eaxEv

Please join us for the Neurobiology of Ingestive Behavior Keystone Conference in spectacular Pacific Grove. vimeo.com/1058375928/2...

2024 was the first full calendar year for Imaging Neuroscience @mitpress - 350 papers published. We're proud of how the brain imaging community enthusiastically embraced open access non-profit publishing. Our aim is to be *your* journal. Full size PDF: drive.google.com/file/d/1M170...

Looking forward to reading this one. www.cambridge.org/core/service...

Very cool! www.science.org/doi/10.1126/...

The scientist who is responsible for driving GLP-1 drugs for the treatment of obesity and testing them for prevention of Alzheimer's disease—Lotte Bjerre Knudsen— tells her story in a remarkable conversation. Full transcript, or video, all free, no ads. erictopol.substack.com/p/lotte-bjer...

Our manuscript was accepted for publication just before Christmas 🎁

One of the amazing wonders of South Pacific Costa Rica.

Interesting new paper showing flavor nutrient conditioning is associated with D2R binding potential, intake and not pleasantness. Also conserved in obesity and after bariatric surgery. journals.plos.org/plosbiology/...

New neighbors. Puntarenas Costa Rica.

Curious to know more about the upcoming Keystone on the Neurobiology of Ingestive Behaviour? April 22-25 in California. Here is a video from lead co-organizer Daniela Cota. youtu.be/iQm1Y66b25Y.

I joined 75+ @nobelprize.bsky.social laureates urging US Senators to oppose RFK Jr.'s confirmation as DHHS Secretary. If you’re in a state with GOP senators, PLEASE reach out to them! I’d deeply appreciate it if you amplified this post! 🙏 www.nytimes.com/2024/12/09/h...

@mikekrashes.bsky.social on GLP-1.

www.keystonesymposia.org/conferences/... this is the better link

www.keystonesymposia.org/digital-tool... Hope to see you all at this upcoming Keystone Meeting. Great list of speakers!

tVNS did not improve gastric interoceptive accuracy or alter water ingestion, but reduced food liking after the fullness phase of the water load. Work by Salaris & Azevedo in Psychophysiology #neuroscience #interoception onlinelibrary.wiley.com/doi/10.1111/...

Fun pic of Alan Spector in Zurich

To all my friends and followers, have a wonderful Thanksgiving holiday.

Black bear came to visit. I was away when it happened but here is a fun video posted by husband.

We have updated and expanded our database of fellowships for POSTDOCS in neuroscience/neurology/cog science. For each fellowship, we provide a description, $ amount, deadline, link, and eligibility criteria. Download our database freely here: research.jhu.edu/rdt/funding-... pic.x.com/eEhXhlOzEj

Very good, concise summary of the gut-brain axis of communication and interoception www.cell.com/current-biol... open-access

This is a good opportunity for the right person. I can recommend it.

NEW in #NatureReviewsGastroHep! This Review on gut-brain axis & pain signalling in the gut By Kim Meerschaert & Isaac Chiu www.nature.com/articles/s41... 🔓 rdcu.be/d1dFo 🧪 #gastrosky #GIsky

Preprint dropped! Excited about this study by Yu Wang, a PhD student from Li Ye's lab and mine, now a postdoc in @deisseroth.bsky.social lab. It unveils an unexpected role for PIEZO2/mechanosensation in sensory neurons that innervate fat! What is it sensing in fat? www.biorxiv.org/content/10.1...

“That is a really disgusting idea,” she said. “But we’re good at making things taste good.” 🙄 How long until the food industry devises new ultra processed foods that counteract GLP1R agonists? In this battle of pharma and food industry, I hope health wins. www.nytimes.com/2024/11/19/m...

I had the opportunity today to give a short retrospective on “the chocolate study”, performed in the late 90s at the MNI using water bolus PET. Old photo of the authors taken at my PhD defense 23 years ago. Happy 40th to the McConnell Brain Imaging Center!

The Brain Imaging Centre (BIC) at the MNI 40th anniversary. Table and zoom of previous BIC directors. One of the first centers in the world and still at the forefront of research.

If you are an undergrad student in the St Louis area and you're interested in a summer 2025 research program please check out ASSURE! assure.wustl.edu

And here it is activated. My favorite brain art piece.

Sensory Biology of Ingestion at Janelia. Organized with Zachary Knight and Kara Marshall. Thanks to everyone for coming and Janelia for their support!

Here's my cat. He's famous.