🚨📃New Wassum Lab Paper📃🚨 Out today, @jackiegio.bsky.social discovered brain pathways that support agency and habit and how chronic stress disrupts them to rob of us our agency and cause us to form rigid habits 🧵👇 www.nature.com/articles/s41... Free full text: rdcu.be/eaxEv

www.science.org/doi/10.1126/... very excited to share our latest work, out now in Science. Congratulations to Marielle who led our studies! And, all other authors - this was a wonderful collaborative effort

New year new work from the lab! We explore whether aggression experience and observation lead to similar changes in future aggression strategy. (They do!) We perform 2-color imaging across the whole social behavior network across time and track changes www.biorxiv.org/content/10.1...

We're so excited to join the party over here! Follow this account to learn more about the latest papers published in Nature Neuroscience!

Reposting new preprint investigating sex-differentially expressed (DE) genes in human ventromedial hypothalamus and arcuate 🧠. Data identifies extensive sex DE, which is linked to genetic risk for sex-biased disorders including autism, depression, and schizophrenia www.biorxiv.org/content/10.1...

My inaugural post on Bluesky - quite fittingly, I'm thrilled to share our first study on heat acclimation, which identifies a neuronal mechanism that drives heat tolerance in mice. (www.nature.com/articles/s41... ) Here is the gist 🧵 (1/n):

Latest from our group in collaboration with Lotte Bjerre Knudsen and other Novo scientists. They developed a GLP-1/Leptin co-agonist that we put through its paces in a number of mouse models to prove that both parts of the molecule matter. More options on the table! www.science.org/doi/10.1126/...

@mikekrashes.bsky.social on GLP-1.

NIH’s own @mikekrashes.bsky.social telling it like it is.

Everyone is talking about #Ozempic #Wegovy which are agonists of the GLP-1 receptor. For more about this receptor and its physiological role, see the quickguide by Michael Krashes in our latest issue www.cell.com/current-biol...

Parallel gut-to-brain pathways orchestrate feeding behaviors www.nature.com/articles/s41...

New work stemming from an amazing collaboration with @addisonwebster0 and @AUGCsoup using a combination of rabies mapping and single cell sequencing to identify a GLP1R-expressing local input to AgRP cells that curbs appetite rdcu.be/d2gB5

A little late for Thanksgiving but if you have friends and family members curious about anti-obesity medications, this is very easy to digest piece (nailed that pun....still got it) authors.elsevier.com/a/1kCED3QW8S...

We've joined the blue skies. Follow along to those interested in all things ingestive behavior. Also, be sure to check out SSIB2025 👉 www.ssib.org/2025/ Neuroskyence: 🧠🟦 or 🧠📈 Interoception: 🧠🫀 or 🧠🫁 Neuropsychiatry: 🧠🩺

Stress, GLP1, hypothalamus, NTS, what more could you want? Collaboration across the pond led by the amazing Dr. Marie Holt @MKBHolt www.sciencedirect.com/science/arti...