Another great study from @nickjonesimmuno.bsky.social lab and collaborators, highlighting a novel metabolic target to modulate T cell function in context of autoimmunity

I am so proud to say that our paper is now available at Aging Cell. There is a paucity of data as to how the menopause impacts your immune system, and the aim of this study was to investigate the impact of the menopause on monocyte phenotype and function. onlinelibrary.wiley.com/doi/10.1111/...

We have a new Postdoc position advertised as part of our recent long-term Wellcome funding to join an established Postdoc and technician. I’m so excited to explore the role of the glycocalyx in CNS-inflammation. So many tools and expertise to work with! www.jobs.manchester.ac.uk/Job/JobDetai...

This was a labor of love requiring lots of teamwork over years, repeating in 3 locations! Thanks to all the lab over the years, giving their time generously to this team project, & our wonderful collaborators. The source of fat matters for anti-tumor immunity 🐄🐖🧈🌴🫒🥥 www.nature.com/articles/s42...

Happy to share our latest preprint doing low cell number (mini-bulk) and single cell #proteomics on tumour associated neutrophils from human glioblastoma where we find multiple functional states that would be invisible to scRNAseq, some showing pro-tumoural states with potential therapeutic value

🦠 New research shows obesity disrupts dendritic cell responses to viruses by impairing cytokine production & metabolism - helping explain higher infection risk. 📖 Read the open-access study: https://bit.ly/40kBiiH By @andrea-woodcock.bsky.social‬ et al. ##Immunology

'Male CD8+ T cells stimulated with IL-15 exhibited greater bystander activation, including increased NKG2D expression and greater antigen-independent cytotoxicity against tumor cells compared with female CD8+ T cells.' #immunology #immunosky onlinelibrary.wiley.com/doi/10.1002/...

Iron deficiency causes aspartate-sensitive dysfunction in CD8+ T cells #immunometabolism www.nature.com/articles/s41...

I'm very pleased to have two lab positions open this week, to join our team looking at immune regulation in infection and co-infection. We're especially interested in tissue-based immunity, cytokine regulation and immune metabolism. Join us! Postdoc (3y) and research technician (12mo) posts open.

First Post on blue-sky. We are hiring! Post-doctoral position available in the neuroimmunology of stroke. Please check out link below and share elxw.fa.em3.oraclecloud.com/hcmUI/Candid...

🚨 new paper alert!! Congrats to Andrea Woodcock on delivering this from during the depths of the pandemic! Thanks to @mary-canavan.bsky.social for the collab. Obesity drives dysregulation in DC responses to viral infection academic.oup.com/discovimmuno...

Online now, our latest manuscript reporting findings on the metabolic basis of cytokine-driven CD4+ T cell expansion, assessed in vitro and during T cell proliferation following autologous stem cell transplantation. www.sciencedirect.com/science/arti...

An excellent PhD opportunity available in our team: long-range consequences of parasite infection, gut-lung communication and helminth-viral co-infection. Part of the EastBio training programme. Closing date 17th January. Please get in touch! www.findaphd.com/phds/project...

Great to have past and present lab members together today to celebrate Taylor’s PhD graduation with her. Nancy, Victoria and Isaac even donned their own robes to join the procession… Congrats Taylor and we wish you all the very best!

#EMDS2024 was brilliant. Thx to all the organisers. Planning is well underway for EMDS25: Scotland Edition. We look forward to welcoming you to beautiful Edinburgh next year. 👀 for details in the coming months. @britsocimm.bsky.social @cytokinesociety.bsky.social @societymucosalimm.bsky.social

There’s a really exciting range of PhD projects on offer through the MRC “AIM” doctoral training partnership between the Universities of Birmingham, Leicester and Nottingham. 4-year funded studentships with great training opportunities too. Check out the options: more.bham.ac.uk/mrc-aim/phd-...

Another PhD opportunity in the team! This time its an exciting collaboration with @halllab.bsky.social and @kimhardie.bsky.social looking at why not all bacteria become resistant! www.findaphd.com/phds/project... Deadline 10th Jan and open to Uk and overseas! Pls repost!

We had a great time today at this fantastic event. So many great science presentations, alongside interesting and thought-proving talks on the progressive history of Manchester and how to build and maintain positive and inclusive research culture in the lab. Thanks all for bringing it together!

It was great to work with Kendle Maslowski’s group @mmimic.bsky.social and others on this project, interrogating the curious question of why T cells aren’t engaged by bacterial cancer therapy, and how to make them so! It’s all down to metabolism of course 😉…

Great opportunity to join our wonderful immunology, infection and inflammation community in Birmingham!

To celebrate the 125th anniversary of the University of Birmingham, we are recruiting 100 Anniversary Fellows and 25 Anniversary Chairs fellowsandchairs.birmingham.ac.uk If you are interested to join our community of researchers in infection, inflammation and immunology, please DM me!

JOB CLAXON! I am recruiting a post-doctoral researcher on a BBSRC-funded project (36 months) on the genetics and functional genomics of vancomycin resistance in enterococci. Further details here: edzz.fa.em3.oraclecloud.com/hcmUI/Candid... Please DM or email me if you want to discuss this post.

Great opportunity here in a supportive lab!