#ScientistSpotlight: This week we’re introducing Verena Körber, one of the newest Group Leaders at the MRC WIMM. @rdm.ox.ac.uk @medsci.ox.ac.uk @ox.ac.uk

We care a lot about time. Now one of my best science friends, Melania Barile, et al. introduce TemporalVAE, a deep generative model that maps scRNA-seq data onto developmental time! It works with zero-shot & identifies time-sensitive genes @natcellbio.nature.com 🧪

Im November macht das #Utopiemobil erneut Halt im #Futurium in #Berlin. Am 13.11. geht es im Rahmen eines 🌟Open Lab Abends🌟ab 17 Uhr um die Zukunft der #Wissenschaftskommunikation. U.a. mit @leoniewenz.bsky.social und @libuchauer.bsky.social Alle Infos:🔗 www.diejungeakademie.de/de/veranstal...

🔍 Wir suchen als Verstärkung eine Leitung für unsere Geschäftsstelle in #Berlin! 📍💼 ✍️ Hier bewerben: karriere.leopoldina.org/jobposting/e... #Job #Stellenausschreibung #Stellenangebot #Organisationsentwicklung #Personalführung #Wissenschaftskommunikation #Wissenschaftsmanagement

Few dates left to apply for this tenure-track professorship on Single-Cell Systems Biology in my department at @uni-wuerzburg.de. Competitive package and highly attractive research environment at the Institute of Systems Immunology.

Postdoc position in our group at @ebi.embl.org about analyzing single cell data sets to better understand and treat neurodegen diseases, in collab with A Bassett, M Lotfollahi, @bayraktarlab.bsky.social, M Strauss and others within Open Targets. Deadline 20/07. Please share tinyurl.com/87wj466m

We have a curator position at @ebi.embl.org to work with GSK within a project to understand fibrotic processes (no PhD required). Deadline 20th July. Please share 🙏 embl.wd103.myworkdayjobs.com/en-US/EMBL/j...

We are currently recruiting a bioinformatics/computational biology postdoc to join the infrastructure project of a newly funded large research consortium (SFB-TRR) on Circadian Medicine between Charité - Universitätsmedizin Berlin and Universität zu Lübeck ⌚ ⏰ ⏱️ 🕰️ !

US terminates its support for @gavi.org the vaccine alliance that supplies life-saving vaccines the world’s poorest. Vaccines are among the safest, most effective prevention measures ever introduced. This is a disastrous and short-sighted decision!

decoupler has been very useful for us & helps you dive into meaningful sc analysis quickly! small suggestion to increase uptake: consider changing the logo, at least two python users here initially immediately closed the tab as they thought is was an R package🙃

💡 Great science needs great environments. We are proud that our Single Cell Focus Area is among the ten “Best Research Environments 2024” – selected by @jungeakademie.bsky.social‬ together with the @volkswagenstiftung.de. Congratulations! 🥳 More details: 👉 www.diejungeakademie.de/en/press/bes... 👈

Honored that our lab made the shortlist for Best Research Environment. Awesome initiative by Junge Akademie and proud of the incredible Gaebler Lab team and the entire Infectious Disease Department at Charité/BIH that makes this place what it is! 👏 @libuchauer.bsky.social @sanderlab.bsky.social

@cgaebler.bsky.social well done :))

🧬Unter den Top 24 der besten Forschungsumfelder ist auch die Single #Cell Focus Area. Sie vereint die Forschung der Charité Berlin, des @bihatcharite.bsky.social, des @mdc-bimsb.bsky.social und des @mdc-berlin.bsky.social. Der Preis wird im Juni ausgelost. 👉 www.diejungeakademie.de/de/projekte/...

Welcome Roberta, excited to have you with us & wishing you good luck!

🚨 Preprint Alert! New work from the group! 🟤 We set out to explore how brown adipose tissue (BAT) adapts to cold. 🧬🖥️ Using single-nucleus mRNA-sequencing, we dissected murine BAT and uncovered distinct adipocyte subtypes. 🫓 One in particular stood out... 🧵 1/7

Guten Morgen Dresden! #tagungmitbabyundschwiegermutterwhatcouldgowrong

📣 Job alert! 📣 We are are looking for a talented bioinformatician to join us at the Berlin Institute of Health at Charité to analyze multiomics data in post-COVID-19 and ME/CSF syndrome research. Please share and come join us! ⬇️ #ImmunoSky #Bioinformatics #Immunology #ComputationalBiology #MedSky

Come and join our seminar series!

I had similar issues about a week ago, I guess the server now unstable with all the staff fired and chaos caused by ElMu and Trump - try the European one: europepmc.org, often anyway more useful as it includes biorxiv.

See you in Dublin in October for the ICSB2024! Early registration is open at: ICSB2025.com. I will chair an exciting session on "Cell Engineering & Pathway Engineering".

Thank you to Stiftung Charité for featuring me and my group in the FACES interview series! www.stiftung-charite.de/en/news-in-d...

Was bringt der Wandel? Wie gehen wir in Wissenschaft und Gesellschaft damit um? Wie verändern sich Wissenschaft und Gesellschaft selbst? Reisen Sie beim #SalonSC durch #Metamorphosen in Geschichte und Gegenwart - am 18.1.25 ab 18 Uhr in der BBAW. salon.bbaw.de/start

Freue mich drauf, heute Abend als neues Mitglied der Jungen Akademie beim Salon Sophie Charlotte salon.bbaw.de/start der BBAW dabei zu sein! Kommt vorbei und lernt unsere Forschung durch ein besonderes Quartett-Spiel kennen 🃏🃏🃏🃏. Raum 230, 19/20/21 Uhr!

This! Also well put in this editorial in PLOS Comp Biol: Putting benchmarks in their rightful place: The heart of computational biology doi.org/10.1371/jour...

Learn how to analyze spatial omics data! Join our computational genomics course in 2025. Application deadline 30th January. compgen.mdc-berlin.de 🖥️ 🧬 🧪

🔗 Dive into this fascinating work here: doi.org/10.1038/s414... . 🏁 Kudos to Anna Huhn et al. for this remarkable contribution to basic immunology! 🧪 5/5

How to do differential expression with scRNAseq data? State of the art is "pseudo-bulk" analysis with RNA-seq methods like edgeR or DESeq2, where "cell type" is encoded as discrete categories. Biologically, discrete categories are not always the most appropriate concept.(1/3) doi.org/10.1038/s415...

LEMUR is directly useable for your next single-cell differential expression project! R package: github.com/const-ae/lemur Python package: pylemur.readthedocs.io/en/latest/ Code from the paper: github.com/const-ae/lem...

Petition der Gewerkschaft der Polizei #GdP für ein bundesweites „Böllerverbot“

🧬 🖥️ Need help for investigating tissue complexity from #spatial #transcriptomics data? Try out our #spacedeconv R package! 💻 Code: github.com/omnideconv/s... 📝 Preprint: www.researchsquare.com/article/rs-5...

Nach den neusten RKI-Zahlen sinken die Impfquoten gegen verschiedene ansteckende Krankheiten wie Polio (Kinderlähmung). Gerade in Kreisen mit ohnehin niedrigeren Polio-Impfquoten (Beispiele Main-Tauber und Deggendorf in der Grafik) ging es drastisch nach unten; deutlich weniger Veränderungen wo…

Impfquoten für Grippe & Pneumokokken sind miserabel in Deutschland. Beides sind günstige, gut verträgliche, sichere Impfstoffe & stellen eine der wirksamsten & einfachsten Präventionsmaßnahmen gegen schwerwiegende Erkrankungen wie Lungenentzündung, ARDS & Sepsis dar! www.rki.de/DE/Content/I...

A few days left to apply if you would like to work on spatial multi-omics modeling in an interdisciplinary team!

HIV - Heilung in Sicht? Sehr informativer und differenzierter Artikel in der @taz.de über die Fortschritte und Herausforderungen in der HIV-Forschung & Therapie und der Lange Weg zur Heilung. @cgaebler.bsky.social gibt spannende Einblicke in seine Forschung an der Klinik f. Infektiologie #Charité

Not checking nuclear markers like MALAT1 or intronic reads in your scRNA-seq data?🚨 We show their power to flag low-quality cells—even in top public datasets. It’s time to prioritize better QC for cleaner, more reliable genomics research! Read more: bmcgenomics.biomedcentral.com/articles/10.... 1/8

Hiring! I'm looking for a postdoc in machine learning of spatial single-cell data. Exciting project to develop methods for modelling cellular circuits in disease and regeneration of heart, liver and bone marrow using Xenium data from our lab. tinyurl.com/ymkvk7vn

Join us for a World Aids day Fundraiser special event at Moviemento Berlin featuring short films curated by Xposed, and short introductions into our research work as well as valuable insights from representatives of TransSe*works and Deutsche Aidshilfe moviemento.de/film/world-a...

Every year, >200K newborns die from sepsis. Our team used machine learning to develop a set of genes that can predict neonatal sepsis risk using at birth blood samples. www.thelancet.com/journals/ebi...

🚨 One week left to apply! 🚨 Don’t miss the chance to join the Gaebler & Ibrahim Labs for a cutting-edge postdoc position at the intersection of viral immunology, virology & gene regulation. 👉Apply here charite.hrpuls.de/de/job-offer...

ConvexGating allows to turn labeled groups/clusters (e.g. those derived with graph based algorithms) of highdim cytometry data into interpretable gating strategies with potential for marker discovery cell sorting -- congrats Maren & team and we will give it a try!

😍 They are so beautiful, how could I not?? I did a whole "mother's milk" series in 2023, when my book Nursery Earth came out, to showcase little-known lactators

well if this isn't what we're here for 🤩

MYCOPLASMA PNEUMONIAE This cheeky little intracellular bacteria seems to be up to mischief with kids in the USA at the moment A quick thread on this bug, what's going on, and what to do (or not do!) about it #IDSky #PedSky #PedsIDSky 🧪 1/🧵

🧬 🖥️ If you are looking for more tools, resources, and insights about next-generation #deconvolution, have a look at our #omnideconv website: omnideconv.org

35 years after the Berlin wall came down. Signs drawn by people from Berlin were put up along 5 kms of where the former wall was standing. Extremely impressive and it somehow gives a tiny bit of hope how many people wrote about democracy.

📢 New preprint alert: Excited to share our deep dive into the role of tandem repeats (TRs) in single-cell gene expression across the immune system, using WGS and scRNA-seq data from 1,790 individuals and over 5 million blood cells! 🧬 🧵👇 #repeats #SingleCell 1/9

Intricate shape of a dendritic cell, guardians of the immune system.

I'm looking for a postdoctoral researcher for a 3-year position on the predictability of evolution using computational modelling: vacatures.uva.nl/UvA/job/Post... Please share!

Bicoid over Paris !