Preprint out! Salamanders harbor a hypersensitive mTOR, thought to enable their remarkable limb regeneration. But do you need a special mTOR to regrow appendages? In Polypterus, we find that a canonical mTOR pathway supports full appendage regeneration. www.biorxiv.org/content/10.6...

Congratulations to Biology Professor Maurine Neiman, PhD (@maurineneiman.bsky.social), on receiving the 2025 IDEA Award! Professor Neiman has spent her career expanding access and inclusion in the evolutionary biology community worldwide. Read more here: biology.uiowa.edu/news/2026/03...

[1/6] Two new preprints out today from the OGA team. We've quantified the ethical costs of poor antibody validation for the first time — and developed a consensus plan to fix it. Thread 🧵

#Dros26 Day 3 Did you know DSHB houses over 1600 Drosophila antibodies? Browse the collection and more: dshb.biology.uiowa.edu 📸 Drosophila germarium labeled with DSHB anti-Vasa (green) and anti-hts (magenta) 🧫 dshb.biology.uiowa.edu/anti-vasa 🧫 dshb.biology.uiowa.edu/1B1

From the meeting so far, here’s what seems in demand in the fly field; tell me I’m wrong. 1. Organelle markers ER, Golgi, endosomes, lysosomes, mitochondria. 2. Post translational modifications phospho-ERK, phospho-AKT, phospho-JNK, ubiquitin chains. 3. Cell-type markers Glia, intestinal cells

Registration is OPEN for the 2026 Santa Cruz Meeting on Developmental Biology!!! Please spread the word! @mads100tist.bsky.social @socdevbio.bsky.social @bsdb.bsky.social @xenbase.bsky.social @isdb.bsky.social @devbiol.bsky.social @the-node.bsky.social scdb2026.sites.ucsc.edu

If you're at #Dros26 and are interested in how cells change shape & move during morphogenesis & how different classic cadherins influence different cell behaviors, check out the talk by @saraheclark.bsky.social in Cell Biology: Cytoskeleton, Organelles, & Trafficking II Sat 9:15 🧪

Check out our booth at #Dros26!

#Dros26 Day 1 Comment below your favorite DSHB antibody! 📸 Drosophila brain labeled with DSHB anti-Bruchpilot in blue 🧫 dshb.biology.uiowa.edu/nc82

🔎 Spotted in Neurobiology of Disease! Researchers from #OhioStateUniversity and @wrightstateu.bsky.social used DSHB's anti-NF-M [2H3] and anti-SV2A mAbs in a study on a new SCN8A epileptic encephalopathy mouse model that depicts seizures and motor impairments seen in patients.

🔎 Spotted in #ScientificReports by @natureportfolio.nature.com! Researchers from #NTUsg used DSHB's anti-CD8A mAb in a study on the role of ARL13B on ciliogenesis and related signaling pathways. 📄 tinyurl.com/2f86jfum 🧫 dshb.biology.uiowa.edu/CPTC-CD8A-1

Spotted in @plosone.org! Researchers from Quillen College of Medicine and @hubrechtinstitute.bsky.social used DSHB's anti-Krt8 [TROMA-I] mAb in a study on Lgr5-positive duct cells in von Ebner’s glands as potential stem cells for regenerating posterior tongue taste buds in mice.

Cooking up the next wave of Drosophila antibodies with Lori Wallrath 🧫🔬 Last day to visit DSHB at booth 1210! Don't miss out! #CellBio2025 #uiowa @ascbiology.bsky.social @embo.org

@dshb-antibodies.bsky.social is returning to ASCB #CellBio2025 stop by and check out what's new at booth 1210

🔎 Spotted in Naunyn-Schmiedeberg's Archives of Pharmacology! Researchers from International University of Health and Welfare, Narita Campus used DSHB's anti-LAMP-1 [1D4B], anti-NCAM [AG1], and anti-synaptic-vesicles [SV2] mAbs in a study on mapping the Neuropeptide Y Y₁ receptor in the mouse brain.

🔎 Spotted in #FASEBJournal! Researchers from @pullman.wsu.edu and @ohsunews.bsky.social used DSHB's anti-β-tubulin [E7] mAb in a study on the effects of Intralipid enhancing fetal sheep adipose growth. 📄 tinyurl.com/3zt6762j 🧫 dshb.biology.uiowa.edu/E7_2

With the HCR™ HiFi Encoder, @dhouston.bsky.social (@uiowabiology.bsky.social) ran two @dshb-antibodies.bsky.social mouse IgG1 antibodies directly from supernatant and achieved robust double-labeling using HCR™ Gold IF. 🔬 Ready to try HCR™ Gold IF? Get a free Starter Kit here: tinyurl.com/37dfdenf

🔎 Spotted in @natbiotech.nature.com! Researchers from @hubrechtinstitute.bsky.social, among others, used DSHB's anti-integrin-β1 [AIIB2] mAb in a study on how an antibody derivative (scTS2/16) enhances human epithelial organoid growth. 📄 tinyurl.com/yu36mt6m 🧫 dshb.biology.uiowa.edu/AIIB2

Thanks to the folks at @HCRimaging for their nifty HCR HiFi encoders: "quantitative signal amplification of 1˚ antibodies for same-isotype multiplexing" 🔑@DSHB_antibodies can be tagged as supernatant, allowing mulplx wo/purification --> here are 2 trusted IgG1s used together

Nice highlight of new genome paper. ❤️ emphasis on leadership of ECR Potamomics team members @kylemcelroy.bsky.social @chelseahiggins.bsky.social @jsharbro.bsky.social Genome Duplication in a New Zealand Snail Holds Clues for the Persistence of (A)sexual Reproduction: academic.oup.com/gbe/article/...

I am so proud & happy to see our Potamo genome assembly finally out there in the world! The process ended up being way more challenging than expected, but for some really cool reasons. ❤️🐌🧬 TLDR: Surprise! A VERY recent WGD. academic.oup.com/gbe/article/... Photo: C. Böck, ILIM, Mondsee, Austria)

How do four-eyed fish see above & underwater? 🌤️🌊 Our new preprint reveals how Anableps rewired its retina for dual vision- evolution at work 👁️👁️ Kudos to @perezlouise.bsky.social @josanesousa.bsky.social @keylapruett.bsky.social + team! 🔗 tinyurl.com/3a8r9xy5

🔎 Spotted in #Virulence by @tandfresearch.bsky.social! Researchers from #WSU Floyd College of Medicine used DSHB's anti-α-tubulin [AA4.3] mAb in a study on how the GCN-2 pathway triggers stress responses in C. elegans during infection. 📄 tinyurl.com/3anhfuhm 🧫 dshb.biology.uiowa.edu/AA4-3

🐸 Xenopus laevis 💚 The frog that shaped modern developmental biology! ✨ Xenopus embryos have revealed how the body axis forms, cells choose their fate, and tissues self-organize during early development 📹 Video by Bioquest Sudio and Xenbase #ModelMonday #DevBio

🔎 Spotted in The Journal of Translational Medicine! Researchers from Sun Yat-sen University, among others, used DSHB's anti-Gingipain/P. gingivalis [61BG1.3] mAb in a study on how P. gingivalis drives cervical cancer metastasis. 📄 tinyurl.com/yzjhb6sx 🧫 dshb.biology.uiowa.edu/61BG1-3

🔎 Spotted in Molecular Genetics and Genomics! Researchers from @ur-ctsi.bsky.social and @ucsandiego.bsky.social used DSHB's anti-HP1 [C1A9] mAb in a study on how CRIF1 suppresses tumors by opposing Ras signaling in Drosophila. 📄 tinyurl.com/4uscst5c 🧫 dshb.biology.uiowa.edu/C1A9

Hey Regen folks 👋 Excited to share that our single-nucleus RNA-seq dataset for Polypterus fin regeneration is now live at the Broad Institute portal! Dive in here: tinyurl.com/5bck22jx Big thanks to the team for making this happen—looking forward to seeing what you all discover!

🔎 Spotted in @natcomms.nature.com! Researchers from @uwmadison.bsky.social, among others, used DSHB's anti-MHC [MF 20] mAb in a study on how deleting ICAM-1 improves the immune resistance of stem-cell grafts. 📄 tinyurl.com/2s3pzheu 🧫 dshb.biology.uiowa.edu/MF-20

🔎 Spotted in Autophagy by @tandfresearch.bsky.social! Researchers from #NationalTaiwanUniversity used DSHB's anti-α-Spec [3A9], anti-dlg [4F3], and anti-spitz mAbs in a study on Rab27’s role in regulating autophagy and lifespan in Drosophila.

Novel monoclonal antibodies against the C-terminal HEAT domain of Huntingtin biorxiv.org/content/10.110… Nice collaboration between @DSHB_antibodies , @LabScribbles and @thesgconline to make and characterize anti-HTT mAbs

🔎 Spotted in Comparative Biochemistry & Physiology Part A! Researchers from @umassamherst.bsky.social and @utaustin.bsky.social used DSHB's anti-NKA-α-subunit [a5] mAb in a study on how red drum larvae adapt acid excretion to survive ocean acidification.

🔎 Spotted in @mucosalimmunol.bsky.social! Researchers from #TongjiUniversity used DSHB's anti-dlg1 [4F3] mAb in a study on how bacterial membrane vesicles suppress CREB to regulate host immunity. 📄 tinyurl.com/yc7f97wk 🧫 dshb.biology.uiowa.edu/4F3-anti-dis...

🔎 Spotted in #ScienceAdvances! Researchers from @uni-muenster.de, #OsnabrückUniversity, and @istaresearch.bsky.social used DSHB's anti-Rab7 mAb in a study on how RabGEF complexes evolved to regulate Rab GTPases in cell trafficking. 📄 tinyurl.com/4rnzfw4k 🧫 dshb.biology.uiowa.edu/Rab7

🔎 Spotted in Proceedings B of @royalsocietypublishing.org! Researchers from @barnard-college.bsky.social, among others, used DSHB's anti-PDF [C7] mAb in a study on how artificial night light influences fruit fly behavior across sexes and genes.

🔎 Spotted in Journal of Advanced Research! Researchers from Heilongjiang Bayi Agricultural University used DSHB's anti-Br-C core [25E9.D7] mAb in a study on how SUMOylation switches Kr-h1 from repressing to activating Br-C during insect development.

Move-in day at Wake Forest … our youngest is off to college!

🔎 Spotted in @plosone.org! Researchers from #TaylorUniversity used DSHB's anti-Dlg [4F3] mAb in a study on how two myosin proteins help align wing hairs in fruit flies via the protein Gliotactin. 📄 tinyurl.com/bdfmzp77 🧫 dshb.biology.uiowa.edu/4F3-anti-dis...

🔎 Spotted in @natcomms.nature.com! Researchers from Huazhong University of Science and Technology used 7 of DSHB's mAbs in a study on how younger gut cells can slow intestinal aging and extend lifespan in fruit flies.

🚨Only 4 days to apply!!!🚨Join the SDB SciComm Internship! Gain hands-on experience writing stories on the latest developmental biology discoveries🔬Connect with top mentors & earn $500 to attend the SDB Annual Meeting 🎉! 👉 www.sdbonline.org/science_comm... #SciComm #DevBio

🔎 Spotted in #BrainResearch by @elsevierconnect.bsky.social! Researchers from #RussianAcademyofSciences used DSHB's anti-SV2 and anti-Na-K-Cl-cotransporter [N161/20] mAbs in a study on age-related GABA system changes in epilepsy-prone rats.

🔎 Spotted in #ScientificReports! Researchers from University of Alabama at Birmingham used DSHB's anti-LAMP-1 [1D4B] mAb in a study on TFEB overexpression, showing it restores lysosomal function in progranulin-deficient cells. 📄 tinyurl.com/3fckjke2 🧫 dshb.biology.uiowa.edu/1D4B

50 years later, hybridomas and monoclonal antibodies are still of "general interest" @dshb-antibodies.bsky.social

🔎 Spotted in #MolecularNeurobiology by @springernature.com! Researchers from #NantesUniversité used DSHB's anti-ISL1/2 [39.4D5] mAb in a study on the impact of gestational protein restriction on fetal hypothalamic development in rats. 📄 tinyurl.com/6n4hbseb 🧫 dshb.biology.uiowa.edu/39-4D5

Cool new paper from the Sokac lab linking apical mRNA localization to the initial events of establishing apical-basal polarity

10 days left to apply for SDB #SciComm Internship. Deadline: August 15. www.sdbonline.org/science_comm...

The UI Department of Biology invites applications for a tenure-track assistant professor position in genetics, beginning in the academic year 2026. Review of applications will begin on November 1, 2025. For more information about the position & to apply, please visit: jobs.uiowa.edu/faculty/view...

🔎 Spotted in #Oncogene by @natureportfolio.nature.com! Researchers from @uhn.ca's Toronto General Hospital Research Institute, among others, used 6 of DSHB's anti-MHC isoforms in a study on the role of pRB and p130 in maintaining adult skeletal muscle integrity and function.

🔎 Spotted in @dmmjournal.bsky.social! Researchers from UAB School of Optometry used DSHB's anti-Islet-1 [39.4D5] and anti-MEIS2 [PCRP-MEIS2-2B4] mAbs in a study on Dhdds mutations in mice cause RP59-related retinal degeneration.

Extra kudos and thanks to all the staff at NIH and NSF and other federal funding agencies for working extra hard in very small windows of opportunity to get grants reviewed and funds released before the attention-addled federal policies change again (on an hourly basis).

🔎 Spotted in @cp-cell.bsky.social! Researchers from @harvard.edu, among others, used DSHB's anti-β-tubulin [E7] mAb in a study on how sea slugs retain stolen chloroplasts to perform photosynthesis. 📄 tinyurl.com/mu7tj6s5 🧫 dshb.biology.uiowa.edu/E7_2