Why do pathological protein aggregates persist in cells and how can we overcome this? In our new preprint, we show that Tau aggregates fail to initiate selective autophagy and that their autophagic degradation can be restored. #Autophagy #Tau #Proteostasis Out now 👇 www.biorxiv.org/content/10.6...

I’m happy to share the main result of my PhD, which you can find on bioRxiv www.biorxiv.org/content/10.6.... If you are interested in learning about a new way to perform DNA-PAINT multiplexing, which we call Combi-PAINT, or if you are interested in the study of mRNA conformation, keep reading! 1/10

Big news! Group leader Sascha Martens has been awarded a prestigious @erc.europa.eu Synergy Grant for the collaborative project DegrAbility to explore how cells can better recycle harmful protein aggregates linked to diseases like Alzheimer’s ➡️ tinyurl.com/2zuz9jcf @univie.ac.at @meduniwien.ac.at

A lipid transfer-dependent feedback loop activates ATG9A compartments in autophagy initiation https://www.biorxiv.org/content/10.1101/2025.08.16.670665v1

Absolutely honoured to see our work featured on this month’s cover! 🎉🧬 Artwork by the incredibly talented @doroteaartscience.bsky.social 👇

WSTF nuclear autophagy regulates chronic but not acute inflammation @nature.com @terjejohansen.bsky.social www.nature.com/articles/s41...

Online Now: Regulation of somatic hypermutation by higher-order chromatin structure Online now:

Thanks for selecting me among all the amazing posters at the symposium :D Also congrats to all other winners 👏

‪We're excited to announce that registration for the "Tiles of Life" Student Symposium is now open! With a fantastic lineup of guest speakers, complemented by SMICH student talks, we’re set for two inspiring days. Don’t miss out—register now! 🚀🎓✨ #TilesofLife #studentsymposium #SMICH

🚨 Paper Alert! We’re starting off the year with our latest publication in @naturecellbiology.bsky.social on the role of phase separation in selective autophagy initiation! This work was a close and exciting collaboration with @wilflinglab.bsky.social 🔗 nature.com/articles/s41... Here's a thread👇

🚨 Out now! Bernd Bauer and the Martens lab reveal in EMBO Journal how the cargo receptor TAX1BP1 faciliates the switch from cargo collection to autophagosome formation, a process crucial for successful aggrephagy - the cell's way of recycling aggregated proteins ♻️ More ➡️ tinyurl.com/35ev5pvv

Check out this list of ubiquitin and Ubl profiles to follow. Repost if you want me to add you to it. Let’s create a good community here ☁️ go.bsky.app/3VPQofn