Thomas Stehlé
@tstehle.bsky.social
📤 883
📥 182
📝 23
Néphrologue HU Henri Mondor
pinned post!
Very happy to share our article just published in @radiology_rsna. If iodinated contrast media such as iohexol or iothalamate are ideal exogenous tracers for measuring GFR, why not use CT urography images to measure it?
pubs.rsna.org/doi/10.1148/...
almost 2 years ago
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reposted by
Thomas Stehlé
Swapnil Hiremath 🍁🇨🇦
13 days ago
Urine crystals in a patient with Crohn’s Answer:
www.kidney-international.org/article/S008...
in
@kidneyint.bsky.social
#NephSky
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reposted by
Thomas Stehlé
American Journal of Kidney Diseases
18 days ago
GFR Measured With Computerized Tomography Urography in Healthy Individuals and Patients With CKD
bit.ly/3XsLlQY
#OpenAccess
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GFR Measured With Computerized Tomography Urography in Healthy Individuals and Patients With CKD - American Journal of Kidney Diseases
www.ajkd.org/article/S027...
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GFR Measured With Computerized Tomography Urography in Healthy Individuals and Patients With CKD
Opportunistic CT-based screening is the practice of exploiting incidental imaging data for prevention, risk profiling, or presymptomatic detection of relevant disease unrelated to the purpose for whic...
https://www.ajkd.org/article/S0272-6386%2825%2901143-6/fulltext
20 days ago
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reposted by
Thomas Stehlé
22 days ago
#LiverCyst #Infection Outcomes in Patients With Autosomal Dominant Polycystic Kidney Disease #ADPKD #VisualAbstract by
Kajaree
https://www.kireports.org/article/S2468-0249(25)00671-0/fulltext
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reposted by
Thomas Stehlé
Iain Bressendorff, MD PhD
2 months ago
A little opinion piece on the relationship between serum calcification propensity (T50) and progressive CAC in kidney transplant recipients 🤓
www.kireports.org/article/S246...
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T50 and Calcification Progression in Kidney Transplant Recipients: Does it have to be “bad” to be useful?
The increased risk of cardiovascular disease (CVD) among kidney transplant recipients (KTR)1 is challenging for the treating physician. For KTR, CVD risk remains higher than for individuals with simil...
https://www.kireports.org/article/S2468-0249(25)00593-5/fulltext
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reposted by
Thomas Stehlé
Pierre Delanaye
2 months ago
www.jle.com/10.1684/ndt....
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JLE - Néphrologie & Thérapeutique - Il était une fois en néphrologie - Épisode 2. Une petite histoire du dosage de la créatinine
https://www.jle.com/10.1684/ndt.2025.139
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reposted by
Thomas Stehlé
KDIGO
2 months ago
Check out the new KDIGO IgAN/IgAV Guideline Key Takeaways! IgAN:
kdigo.co/KDIGO-IgAN-G...
IgAV:
kdigo.co/KDIGO-Guidel...
These resources are designed to provide clinicians with quick and practical access to the most important points from the new KDIGO guideline on managing
#IgAN
and
#IgAV
.
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Low Cystatin C–to–Creatinine Estimated GFR Ratio Predicts Post–Kidney Transplant Cardiovascular Events - Kidney International Reports
www.kireports.org/article/S246...
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Low Cystatin C–to–Creatinine Estimated GFR Ratio Predicts Post–Kidney Transplant Cardiovascular Events
A low cystatin C–based to creatinine-based estimated glomerular filtration rate (eGFR) ratio (eGFRcys/eGFRcr) is associated with poor clinical outcomes, but data in kidney transplant recipients (KTRs)...
https://www.kireports.org/article/S2468-0249%2825%2900535-2/fulltext
2 months ago
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reposted by
Thomas Stehlé
Jonathan Zuckerman MD PhD
3 months ago
Nice example of urate crystals in gouty tophi involving the medulla. Polarizable crystals can be see using unstained sections from the IF tissue.
#renalpath
#pathsky
#nephsky
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reposted by
Thomas Stehlé
Juan Carlos Q Vélez, MD
4 months ago
The Maltese Cross 🇲🇹🛡️sign is not unique to lipids, other structures can manifest it under polarized light (eg, starch, leucine crystals). Here, a rare sighting of a cast containing suspected ciprofloxacin crystals.
#UrinarySediment
#UrineMicroscopy
#PisseProphet
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reposted by
Thomas Stehlé
Hôpitaux Universitaires Henri-Mondor AP-HP
5 months ago
La coordination de prélèvement d’organes était hier au marché de Créteil pour la Journée Nationale Du Don d’organes. Rendez-vous ce mercredi 25 juin à l’hôpital Henri-Mondor, hall principal, de 9h à 16h30 pour en savoir plus et se sensibiliser !
@ap-hp.bsky.social
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reposted by
Thomas Stehlé
ASN Publications
6 months ago
Needle selection in kidney biopsy requires balancing risk of complications with benefit of obtaining diagnostic tissue. Study shows that higher needle gauge provides more tissue for diagnosis but might be associated with greater risk of complications.
https://bit.ly/KID0835
#ASNKidney360
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reposted by
Thomas Stehlé
NEJM.org
7 months ago
Presented at
#ECO2025
: In the SURMOUNT-5 phase 3b trial involving adults with obesity without type 2 diabetes, tirzepatide was superior to semaglutide in reducing body weight and waist circumference. Full trial results:
nej.md/44ZeMPz
@easoobesity.bsky.social
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reposted by
Thomas Stehlé
Swapnil Hiremath 🍁🇨🇦
7 months ago
In the
@annalsofim.bsky.social
www.acpjournals.org/doi/10.7326/...
from
@ucalgarymed.bsky.social
team Saline suppression test not useful in confirming primary
#aldosteronism
- go straight to AVS if planning Sx (and ramp up MRA to target renin if Medical management)
#NephSky
#EndoSky
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Confirmatory Testing for Primary Aldosteronism: A Study of Diagnostic Test Accuracy: Annals of Internal Medicine: Vol 0, No 0
Background: Confirmatory testing to verify the diagnosis of primary aldosteronism (PA) in patients who have an abnormal screening result is of uncertain benefit. Objective: To perform a blinded assess...
https://www.acpjournals.org/doi/10.7326/ANNALS-24-03153
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reposted by
Thomas Stehlé
American Journal of Kidney Diseases
7 months ago
Urea to Treat Hyponatremia Due to Syndrome of Inappropriate Antidiuretic Hormone Secretion: A Systematic Review and Meta-Analysis
bit.ly/3XM0b53
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Myosteatosis, the infiltration of fat into muscles, is associated with the risk of surgical complications after kidney transplantation. This is what we have shown in this study involving the nephrology, radiology and urology departments at
@hophenrimondor.bsky.social
.
doi.org/10.1002/jcsm...
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Myosteatosis as a New Risk Factor of Surgical Complications in Kidney Transplant Recipients: A Retrospective Study
Background Computed tomography (CT) scan–defined myosteatosis is a common feature in ESKD patients receiving kidney transplantation (KT) and is associated with mortality after KT. We aimed to explor...
https://doi.org/10.1002/jcsm.13746
7 months ago
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reposted by
Thomas Stehlé
Pierre Delanaye
7 months ago
Discrepancies between creatinine- and cystatin C-based equations: Less dicrepancies with EKFC (and LMR) equations than with CKD-EPI equations! free access thanks to all co-authors
www.sciencedirect.com/science/arti...
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Discordant Results Between Creatinine- and Cystatin C-based Equations for Estimating GFR
Discordant results between cystatin C and creatinine in estimating glomerular filtration rate (GFR) are an important medical issue. However, the equat…
https://www.sciencedirect.com/science/article/pii/S2468024925000555
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reposted by
Thomas Stehlé
Juan Carlos Q Vélez, MD
8 months ago
Interested in learning more about the art of microscopic examination of the urinary sediment and its clinical applications?
@jrseltzer.bsky.social
@swethakanduri.bsky.social
and I will be running a Hands-On Workshop at KidneyCon this year. Come join us!
@kidneycon.bsky.social
May 1-3. Register ASAP
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reposted by
Thomas Stehlé
Pierre Delanaye
9 months ago
One question was still open: is the diabetic status (in itself) influencing the performance of eGFR? We show the answer is No
academic.oup.com/ndt/article/...
@tstehle.bsky.social
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Diabetic status and the performances of creatinine- and cystatin C–based eGFR equations
ABSTRACTBackground. The estimation of glomerular filtration rate (GFR) is one tool to detect renal disease. The most used biomarker remains serum creatinin
https://academic.oup.com/ndt/article/40/3/516/7715041?login=true
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reposted by
Thomas Stehlé
Stéphane Burtey
10 months ago
Enfin un papier qui répond de façon claire à ce qu'on soit faire devant du BK virus. Réduire l'IS et ne pas mettre d'everolimus. Bravo aux auteurs.
www.kidney-international.org/article/S008...
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Insights from the BKEVER Trial comparing everolimus versus mycophenolate mofetil for BK Polyomavirus infection in kidney transplant recipients
The MTOR inhibitors have demonstrated antiviral properties, and prior non-randomized studies have suggested they may have a suppressive effect on BKPyV replication. Here, in this randomized, multicent...
https://www.kidney-international.org/article/S0085-2538(24)00730-0/fulltext
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reposted by
Thomas Stehlé
ISNkidneycare
10 months ago
➡️ A Targeted Release Capsule of Lanthanum Carbonate: a New Efficient Cheap Treatment for Primary Hyperoxalurias
www.kireports.org/ar...
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This GFR calculator, available on the French-speaking Nephrology Society website, includes EKFC equations in addition to CKDEPI equations, as well as pediatric equations. It can be used across the whole age spectrum, even by non-French-speaking nephrologists!
www.sfndt.org/professionne...
add a skeleton here at some point
10 months ago
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reposted by
Thomas Stehlé
Pierre Delanaye
10 months ago
Can we trust eGFR results? The answer of IA !
bmcnephrol.biomedcentral.com/articles/10....
trustekfcegfr.shinyapps.io/GFR_shiny_La...
Thanks to the EKFC! Thanks to Antoine Lanot
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Enhancing individual glomerular filtration rate assessment: can we trust the equation? Development and validation of machine learning models to assess the trustworthiness of estimated GFR compared to ...
Background Creatinine-based estimated glomerular filtration rate (eGFR) equations are widely used in clinical practice but exhibit inherent limitations. On the other side, measuring GFR is time consum...
https://bmcnephrol.biomedcentral.com/articles/10.1186/s12882-025-03972-0
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reposted by
Thomas Stehlé
10 months ago
1/Hey
#NephSky
! Welcome to a 🆕
#MedSky
#Skytorial
brought to you by
@kireports.bsky.social
@isnkidneycare.bsky.social
! Our author is
@elbaonelida.bsky.social
nephrologist at Hospital General de Mexico @hgm_nefrologia. Please also check out
#KIReportsCommunity
educational
#blogposts
. FOLLOW US!
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reposted by
Thomas Stehlé
Juan Carlos Q Vélez, MD
11 months ago
1/n One of the things that I find valuable in internal medicine in general is pattern recognition. And nephrology is not the exception. AKIs come in different flavors, we can smell the etiology based on the presentation and the way the serum Cr (sCr) rises.
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reposted by
Thomas Stehlé
Dr Anastasia S Mihailidou PhD FAHA FCSANZ FESC
11 months ago
Misclassification of Hypertension Status According to Office
#BloodPressure
vs 24
#ABPM
#CardioSky
#MedSky
#NephSky
❤️seeing further studies confirm the power of
#ABPM
for
#hypertension
control! Congratulations
@hswapnil.bsky.social
& coauthors
www.sciencedirect.com/science/arti...
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Misclassification of Hypertension Status According to Office Blood Pressure versus 24-Hour Ambulatory Blood Pressure Monitoring
Ambulatory blood pressure monitoring (ABPM) is the “gold standard” for establishing the diagnosis of hypertension yet remains under-utilized in Canada…
https://www.sciencedirect.com/science/article/pii/S2589790X25000356
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If you are interested in the relationship between creatinine excreted by glomerular filtration and muscle mass assessed by CT, you can read our study where we used this relationship to model the only creatinine-based eGFR equation that is race, gender, and age free.
doi.org/10.1093/ckj/...
add a skeleton here at some point
11 months ago
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reposted by
Thomas Stehlé
Swapnil Hiremath 🍁🇨🇦
12 months ago
Another in-human pig kidney xenotransplantation After Boston, it’s back to
@nyunephro.bsky.social
www.npr.org/sections/sho...
#NephSky
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A transplanted pig kidney offers a grandmother hope for life without dialysis
The patient was in kidney failure and her immune system would reject a human organ. Scientists hope genetically modified pig organs prove safe and will alleviate the organ shortage and save lives.
https://www.npr.org/sections/shots-health-news/2024/12/17/nx-s1-5203056/pig-kidney-transplant-gene-edited
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reposted by
Thomas Stehlé
David S. Goldfarb MD
12 months ago
Exciting day - story hel for 3 weeks -
@nyunephro.bsky.social
www.cnn.com/2024/12/17/h...
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She donated a kidney years ago. Last month, she received a kidney transplanted from a gene-edited pig | CNN
Towana Looney is the only person in the world living with a functional pig kidney. But her doctor predicts that in less than a decade, pig-to-human organ transplants like hers could become routine.
https://www.cnn.com/2024/12/17/health/third-pig-kidney-transplant/index.html
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reposted by
Thomas Stehlé
Société francophone de néphrologie, dialyse et transplantation
12 months ago
🚨La SFNDT vient de publier une nouvelle fiche pratique "Standardisation de la clairance plasmatique de l’iohexol : un consensus du consortium EKFC" à retrouver ➡️
www.sfndt.org/actualites/s...
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reposted by
Thomas Stehlé
Florian Buchkremer
12 months ago
1/5 The
#SWEETSTONE
results were presented at the Swiss Society of Nephrology meeting: Impact of
#empagliflozin
on urinary supersaturations in kidney stone formers. Randomised, double-blind, placebo-controlled, cross-over trial.
#nephsky
#nephrolithiasis
#flozinator
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reposted by
Thomas Stehlé
Juan Carlos Q Vélez, MD
12 months ago
1/n happy to share a recent publication from Ochsner Nephrology at Kidney International Reports
@kireports.bsky.social
Nice visual abstract by Priti Meena. Link here:
www.kireports.org/article/S246...
But let me tell you the story a little bit…
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reposted by
Thomas Stehlé
Daniel Fuster
about 1 year ago
Acidosis and CKD
journals.lww.com/cjasn/citati...
"Whether there will be a definitive, adequately powered trial of this inexpensive, fairly safe intervention in CKD is up to funding agencies to decide" Cardiology is doing large outcome trials with colchicine - why can we not do this with alkali ?
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https://journals.lww.com/cjasn/citati..
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reposted by
Thomas Stehlé
Stéphane Burtey
about 1 year ago
Intérêt majeur des iSGLT2 chez le transplanté rénal diabétique, réduction de la mortalité et des MACE.
pubmed.ncbi.nlm.nih.gov/39567483/
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The outcomes of SGLT-2 inhibitor utilization in diabetic kidney transplant recipients - PubMed
Sodium-glucose cotransporter 2 inhibitors (SGLT-2i) have demonstrated efficacy in reducing cardiovascular events and potentially improving kidney function in diabetic patients. This investigation anal...
https://pubmed.ncbi.nlm.nih.gov/39567483/
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reposted by
Thomas Stehlé
Altmetric
about 1 year ago
We strongly suggest that academic publishers and other platforms that host research rapidly implement a Share to Bluesky button for their articles. Here's how:
docs.bsky.app/docs/advance...
#AcademicSky
#HigherEd
#Altmetrics
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Action Intent Links | Bluesky
Authors, websites, and apps can use action intent links to implement "Share on Bluesky" buttons, or similar in-app actions. Logged-in users will be directed to the corresponding action view in the Blu...
https://docs.bsky.app/docs/advanced-guides/intent-links
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Urinary cystine crystals visible even before microscopic analysis. Urinary supersaturation due to insufficient alkaline therapy and high urine concentration.
#UrinarySediment
about 1 year ago
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reposted by
Thomas Stehlé
Erin Michos, MD
about 1 year ago
So exciting!
#SUMMIT
trial, the first
#HFpEF
trial of incretin therapy with HF clinical outcomes as prespecified primary outcome. And
#tirzepatide
reduced CV death or worsening HF by significant 38%! Improvement in KCCQ quality of life by 7 pts, wt loss 12%, hsCRP reduction by 35%!
#AHA24
#CardioSky
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Very happy to share our article just published in @radiology_rsna. If iodinated contrast media such as iohexol or iothalamate are ideal exogenous tracers for measuring GFR, why not use CT urography images to measure it?
pubs.rsna.org/doi/10.1148/...
almost 2 years ago
1
5
2
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