Nephrologists deported Grants defunded NIDDK folded into National Institute of body parts AHRQ demolished Now this… When are our organizations going to speak up? #NephSky

Hilarious (and sobering) essay on the use of AI in medical research & manuscript writing Read the whole thing! John Daugirdas has been on the cutting edge of tech in meded before #MedEd was thing onlinelibrary.wiley.com/doi/10.1111/... #MedSky #NephSky

I am BEGGING major journals to stop platforming the current administration's politicization of the FDA, CDC, vaccines, etc This sort of evidence-lite, glitzy puff piece seems appropriate for a newspaper OpEd, not a medical journal. Platforming it in a major journal gives it the veneer of validity.

It's been a long journey but today we can share the methods and rationale for the #ACHIEVEtrial (Spiro vs placebo for patients with kidney failure receiving maintenance dialysis) and tomorrow we share the results at #era25 journals.sagepub.com/doi/10.1177/...

Update to our supersaturation and kidney stone risk assessment tool: We have added calcium to citrate ratios to the result section providing even greater risk assessment tools to the kit. Thanks very much to Vladimir Belostotsky for the idea! ukidney.com/calculators/...

This systematic review shows blood pressure reduction from sodium reduction in the context of antihypertensive medication use. Blood Pressure–Lowering Medications, Sodium Reduction, and Blood Pressure | Hypertension www.ahajournals.org/doi/10.1161/...

This is such a great resource: www.kidney-international.org/article/S008... #nephrology #eGFR

🧵5 Top Free Alternatives to BioRender for Scientific Illustrations! These five websites offer free scientific illustrations for biologists. Great for presentations, research papers and other research communication needs. Save and share the post!

This is so exciting! The German National Library of Medicine @zbmed.bsky.social just had its first open meeting on the plan for an open & independent PubMed safety net. Here's my write-up @plos.org on the meeting & how institutions & others can help absolutelymaybe.plos.org/2025/05/14/g... #MedLibs

Amiloride was noninferior to spironolactone in lowering home systolic blood pressure at 12 weeks. https://ja.ma/42XMGD9

RBC cast - brightfield with SM stain - from new case of MPA - #UrineMicroscopy #UrinarySediment

Thrilled to unveil the first-in-human use of #apelin in #hyponatremia at #ECE2025 in Copenhagen. Endless gratitude to @christ-crain.bsky.social for championing bold research paths, and to @julierefardt.bsky.social and @fichapman.bsky.social, whose groundwork paved the way for this endeavor

This is absolutely amazing! 👏👏👏👏👏👏👏👏👏👏👏

🧵 Introducing the EQUIL2 Urinary Supersaturation Calculator A powerful web-based tool for nephrologists and researchers to assess kidney stone risk with ease. Based on the validated EQUIL2 algorithm from peer-reviewed scientific literature. ukidney.com/calculators/... 1/3

A quick #VEXUS thread 🧵- 3 reasons why the portal vein is the most useful single venous doppler waveform 🥇 (if you're only going to do ONE site to look for venous congestion, this is probably the most useful one!) #emimcc

8/Simultaneous publication #ISNWCN www.nejm.org/doi/full/10....

Another @nejm.org simultaneous publication during #ISNWCN, about xenotransplantation Xenotransplantation of a Porcine Kidney for End-Stage Kidney Disease www.nejm.org/doi/full/10....

#UTHR United Therapeutics Corporation Announces FDA Clearance of its Investigational New Drug Application for the UKidney Xenotransplantation Clinical Trial https://www.stocktitan.net/news/UTHR/united-therapeutics-corporation-announces-fda-clearance-of-its-i9jdr5owbet7.html

Auschwitz was at the end of a long process. It did not start from gas chambers. This hatred was gradually developed by humans. From ideas, words, stereotypes & prejudice through legal exclusion, dehumanization & escalating violence... to systematic and industrial murder. Auschwitz took time.

This is interesting Aerococcus sanquinicola and Aerococcus urinae in the urine metabolizing creatinine resulting in false low readings with implications for UPCR, UACR and 24 hour urine creatinine collections www.kireports.org/article/S246...

This is me : this is how I scan electronic health records when I try to find the cause of a kidney issue or sort out a complicated medical history. I have refrained from using the phrase "binary search" with my trainees as many will tune out because "computers," but perhaps I should start?

Doing a fistulagram and the wire goes through a 99% blocked stenosis on the first try! @asdinnews.bsky.social

SGLT2 Inhibitor #SGLT2i in #Diabetic and #NonDiabetic Renal #Transplant Recipients #VisualAbstract by @DrPSVali www.kireports.org/ar...

1/17 [Why] is furosemide susceptible to malabsorption from "gut edema"? When a patient with heart failure is hospitalized with congestion I often hear "let's use IV furosemide; they're probably not absorbing the PO." It's a comment unique to furosemide. But is it accurate?

Went up slightly from 30 to 35 mmol/d.

Many putative mechanisms how RSR CaP can affect CaOx stone formation (Randall, heterogeneous nucleation etc), but also threats ( increase in urine calcium). This is why we need outcome data

SGLT2is likely inhibit citrate reabsorption in the PT. No need for alkalosis. Urine citrate and pH drove reduction in RSR CaP. Urine calcium went up in patients with calcium stones, no change in oxalate.

Or @danfuster.bsky.social?

This is all really interesting! Suggests to potential benefit in CaOx? But then why such big population effects? And caox in the EMPASTONE trial?

Sorry should read ‘no’ potential benefit. What happened to the phosphate excretion?

Interesting, important. Need UpH data. We can hope that CaP RSR is relevant to CaOx prevention; if Ucit went up why didn’t RSR for CaOx go down? Not sure how drug leads to ⬆️Ucit. Implies tubule seeing met alk but sHCO3 prolly didn’t change. For UA ⬆️cit implies ⬆️UpH

Do AKI and cardiac biomarkers predict AKI progression in the setting of acute heart failure? New data from the AKINESIS study www.ahajournals.org/doi/full/10.... #AHA24 #CardioSky #MedSky #NephSky

1/5 The #SWEETSTONE results were presented at the Swiss Society of Nephrology meeting: Impact of #empagliflozin on urinary supersaturations in kidney stone formers. Randomised, double-blind, placebo-controlled, cross-over trial. #nephsky #nephrolithiasis #flozinator

I’m biased (local PI, steering committee), but the quality of #NOSTONE far exceeds most (if not all) data that the critics base their many assumptions and beliefs on. You can speculate about the additional effects of citrate or a different type or dose of diuretic, … 1/2

Watching Alien Resurrection (a movie set in year 2381) and the doctor uses a gonioscopy lens (a mirror designed to press against the eye to examine anterior chamber angle) as some sort of cross cover examination tool (a technique to evaluate eye muscles) and I have nobody to talk to about this.

Now that we have CysC as part of our BMP, I am trusting it less and less. Particularly in hospitalized patients who are inflamed at baseline. I just think this is a particularly instructive case because we could have just assumed that the creatinine was wrong because of her age and size.

12/12 in conclusion, be bold, NE + Lasix works and does not throw pts back into HRS. Push the MAP up, diurese away.

Wasn’t able to join the #NephJC chat tonight, so I hope they don’t make me give back my #NephJCKidneys Most Engaged Scientist award. Thanks again to the best colleagues who live in my phone!

Beautiful! 👏👏👏

What fun to teach fellow endocrinologist about #hyponatremia and #avp-deficiency together with prof. Mark Sherlock at the Erasmus Endocrinology cursus! Being the broad specialist he is, Mark then went on to rock the plenary lecture on adrenal incidentalomas 💪😎

#Pseudohyponatremia is commonly labeled a “lab error“. It is NOT. The problem results from our custom of reporting sodium concentrations in PLASMA instead of PLASMA WATER. (Only the latter approximates the biologically relevant ionic activity.) #nephsky #skyneph #hyponatremia

An incredible photo posted today by French President Emmanuel Macron. The floor of Notre Dame Cathedral is filled with the workers involved in the 5 year project to restore the building following the devastating fire in 2019. 1/2

Beyond the Urizon! @annagaddy.bsky.social @swissnephro.bsky.social www.renalfellow.org/2021/11/09/u... #NephSky

When you cannot wait for the lab… PD effluent 🔬 microscopy & a UA dipstick can give you the info needed quickly. #NephSky #HolidayOnCall 🦃

"What do you mean, "How do I know everyone?" We all went to Twitter together."

The latest salvo in the hyponatremia wars takes off where Seethapathy left us (NEJM Evidence | NephJC). Last week, Juan Carlos Ayus published his latest study (JAMA Internal Medicine) on hyponatremia, a meta analysis of patient outcomes in the management of hyponatremia pbfluids.com/2024/11/its-...

There we are! Right alongside journalists and Pokemon fans! @hswapnil.bsky.social killing it!