"The Self-Evidencing Agent" - my new book - is out now with @mitpress.bsky.social Can be purchased, or just download the whole thing for free, via the 'Open Access' option. I'm grateful to @anilseth.bsky.social and Karl Friston for the generous endorsements. mitpress.mit.edu/978026255389...

Maths! And Brains! In Melbourne!! Swoon 🧠 ECRs, you only have until 20th Feb to submit your abstracts. Registration is free (but you must attend) & prizes awarded to the highest quality posters and flash talks. Submit your abstracts here & see 👇 for more lnkd.in/dZtndkH3

📢Maths in the Brain Workshop 2026 in Melbourne. We will bring together researchers across Australia with a shared interest in understanding the brain from a quantitative perspective. This year's keynote is delivered by Professor James Cole, University College London. 1/4🧵

Thread 2: A way to see a stochastic differential equation is the equation below representing how X evolves in time. dW is a "stochastic increment" -- it is introducing "randomness". But a LOT changes because of that, and it is the reason the below representation is not actually a good one! (1/n)

What do we actually mean when we say “generative model” in neuroimaging? The term is everywhere, in neuroscience and AI, but its meaning is often assumed rather than stated. In a new bioRxiv perspective, we asked how researchers really use and understand it. 🧵

Our new paper, led by Brett Kagan and Valentina Baccetti, proposes a quantifiable, substrate-independent hierarchy of information processing to identify necessary conditions for agency, grounding agency in measurable dynamics rather than vague labels. arxiv.org/abs/2601.03498

I am in Karachi. Let’s meet if you like to talk about brains, models, and machines!

1/ Why does RL struggle with social dilemmas? How can we ensure that AI learns to cooperate rather than compete? Introducing our new framework: MUPI (Embedded Universal Predictive Intelligence) which provides a theoretical basis for new cooperative solutions in RL. Preprint🧵👇 (Paper link below.)

Joint modelling of brain and behaviour dynamics with artificial intelligence www.nature.com/articles/s41...

📢Generative Models in Neuroimaging Survey We’re running a short survey on how neuroimaging (aka #OHBM) community defines, uses & evaluates generative models, from biophysical simulations to ML-based approaches 👉 t.co/lRQj4qmknO @ohbmofficial.bsky.social @ohbmtrainees.bsky.social

Jonny Smallwood @themindwanders.bsky.social was a beloved friend and mentor. He was taken from us too soon. His was a beautiful mind who understood the beauty of minds. As ever before, his kind voice guides me and his work will continue. We miss you Jonny. www.cbs.mpg.de/news/obituar...

What is consciousness, and could AI have it? It's an honour to be giving the 2025 Voltaire Lecture, this Hallowe'en (Fri 31/10), for @humanists.uk, at @conwayhall.bsky.social in London, 19:30-21:00 (also livestreamed) humanists.uk/events/volta... 👻

Submit -- less than a week remaining!! #NeuroAI

This is BIG. Nobody was expecting this cure to work or even if it was possible ever to treat HD!

We are hiring for our psilocybin clinical trial. 1. Research Officer (testing and screening), 2 positions careers.pageuppeople.com/513/cw/en/jo... 2. Research Officer (Peer Navigator) careers.pageuppeople.com/513/cw/en/jo... DM if you have questions. @wellcomeleap.bsky.social

Thank you very much @prelights.bsky.social and uMontreal Neuro team for coosing and covering our preprint.

Integrating and interpreting brain maps | doi.org/10.1016/j.ti... Imaging and recording technologies make it possible to map multiple biological features of the brain. How can these features be conceptually integrated into a coherent understanding of brain structure and function? ⤵️

We are hiring for our brand new psilocybin clinical trial. Please DM if you have questions! 1. Senior Research Fellow (Clinical Trial Lead) careers.pageuppeople.com/513/cw/en/jo... 2. Senior Clinical Psychotherapist careers.pageuppeople.com/513/cw/en/jo...

Very much forward to this @ohbmofficial.bsky.social

Do you like brain network hubs?🧠🌐✳️Do you like genes?🧬What about neurodevelopment?👶What if I told you the latest work by @garedaba.bsky.social and myself combined all of these?🤯🤯🤯 See Gareth's thread for a primer of our findings, then read the paper for the details! www.biorxiv.org/content/10.1...

Can a Universal Basic Income (UBI) become feasible—even if AI fully automates existing jobs and creates no new ones? We derive a closed-form UBI threshold tied to AI capabilities that suggests it's potentially achievable by mid-century even under moderate AI growth assumptions:

🧵Training binary or spiking neural networks is hard. Gradients vanish, surrogates are noisy, batchnorm is brittle. We propose a Bayesian approach based on KL divergence minimization—and it works. Paper: arxiv.org/abs/2505.17962 Work by James Walker & Moein Khajehnejad @neuro-ai.bsky.social 1/6

Why do brains rely on inference, uncertainty, and structure… while AI systems chase rewards in unstructured worlds? Are we missing something fundamental about how intelligence emerges? #NeuroAI #InferenceOverOptimization

Re-posting is appreciated: We have a fully funded PhD position in CMC lab @cmc-lab.bsky.social (at @tudresden_de). You can use forms.gle/qiAv5NZ871kv... to send your application and find more information. Deadline is April 30. Find more about CMC lab: cmclab.org and email me if you have questions.

Good news - the opening for a Research Officer role within our group is now open to all applicants! Please apply if you would like to join a great team to help with recruitment and assessment on a large project linking MRI with psychopathology! careers.pageuppeople.com/513/cw/en/jo...

Huge congrats to @adeelrazi.bsky.social @leonovelli.bsky.social and team on this monumental achievement - a valuable open resource for the community!

ONE DAY LEFT of Early Bird registration rates! Register today! 🔗 in comments! #OHBM2025

"These findings provide a new account of the large-scale neurocognitive effects of psychedelics and demonstrate the utility of using machine learning methods in assessing state- and context-dependent neural dynamics and their association with psychological outcomes." www.biorxiv.org/content/10.1...

Interested in foundation models for #neuroscience? Want to contribute to the development of the next-generation of multi-modal models? Come join us at IVADO in Montreal! We're hiring a full-time machine learning specialist for this work. Please share widely! #NeuroAI 🧠📈 🧪

We are hiring! We're looking for a Research Office to help out with recruitment & assessment on a large-scale study looking at the relationship between brain imaging measures and psychopathology. Please forward this link to anyone who might be interested: careers.pageuppeople.com/513/ci/en/jo...

🚨 We are excited to announce that the next OHBM Australia meeting will be in Melbourne on Wednesday, 12th November, 2025! Stay tuned for more details 👀

📢 Join us Thursday, April 3rd | 5–6 PM EST for the first NeuroAI Emerging Leaders Webinar with @anayebi.bsky.social 🧠 Title: Using Embodied Agents to Help Answer “Why” Questions in Systems Neuroscience For further updates, visit: 🔗 neuroai-workshop.github.io//NeuroAI_Web... @neuro-ai.bsky.social

Nature Reviews Physics Network renormalization www.nature.com/articles/s42...

It's finally here! Use the Network Correspondence Toolbox to help contextualize your neuroimaging findings 🧠

🧩New study: "Network Constraints on 𝘪𝘯 𝘷𝘪𝘷𝘰 Synaptic Alterations in Schizophrenia" medrxiv.org/content/10.1... We map a prominent brain-wide pattern of synaptic defects in people with Schizophrenia using PET, then model the molecular, cellular & connectomic features shaping this pattern 🧵1/3👇

Can't believe I missed this until now - truly incredible work and real landmark paper in psychedelic neuroimaging!

One of the first real "wow" studies of 2025. Fascinating imaging work demonstrating how context and environment fundamentally shape a psilocybin experience.

Ok, kiddos. This neuroimaging study (Monash U) explains why why you shouldn't approach psychedelics - especially psilocybin - as a clubbing or party drug. It is so, so much more important than that. My foolish youth, corrected!

🧵 How do psychedelics shape brain activity? Our new paper presents the largest neuroimaging study of psilocybin to date—revealing how context structures psychedelic brain states. Title: Psychedelics Align Brain Activity with Context Paper: lnkd.in/gt-kMR6d A thread 🧵👇 1/n

Can we enhance interoception by controlling the heart? Thrilled to share our new study, led by @ashleytyrer.bsky.social , where we use computational modeling to show that blockading peripheral noradrenaline uniquely alters awareness of heart rate & breathing! www.biorxiv.org/content/10.1... 🧵👇

1/ "A science of consciousness beyond pseudo-science and pseudo-consciousness" is out now! it was a joy to coauthor this commentary with Àlex Gómez-Marin @behaviOrganisms for @NatureNeuro, in which we try find some positive lessons in the clash over IIT www.nature.com/articles/s41...

Can we use brain scans to identify biologically distinct "autisms"? And If so, how? In our latest cross-species study 🐭👨 with @iitalk.bsky.social we dive into these questions! Find out more here 👇👇 www.biorxiv.org/content/10.1... Thread below 🧵 1/n

Happy to have this published …https://www.science.org/doi/10.1126/sciadv.adr6698

Very honoured to be giving this year’s keynote at the OHBM annual meeting. And to share this with some of the best in human brain mapping is exhilarating! @lucinauddin.bsky.social @ptenigma.bsky.social @sharnajamadar.bsky.social @joanacabral.bsky.social @gozziale.bsky.social Melani Boly, Aaqi Qiu

Our latest preprint by @jchrispang.bsky.social and a massive team showing how geometry constrains regional patterning of the mammalian brain. 100s of brain maps, >20 species, & plenty of modelling. Congrats to James on this huge effort. Peep the thread for more info…

Thanks to all who came to support and watched online! A recording is available here: www.youtube.com/live/6LSfkQk...

Out in @natureneuro.bsky.social today 🥂 Cytoarchitecture, wiring and signal flow of the human default mode network Combining 3D histology, 7T MRI, and connectomics to explore DMN structure-function associations Led by Casey Paquola, @themindwanders.bsky.social & a terrific team of colleagues 🙏

Here is the open access link to the complete recording (of more than 8 hours) of our NeuroAI worskhop at NeurIPS 2024. lnkd.in/grNZHMQJ It also includes all the slides and links to all 43 papers presented during the workshop. #NeuroAI @neuro-ai.bsky.social

Happy 30th birthday year to SPM!! 🎈🍰 To get the party started, we are delighted to announce SPM 25.01, a major new version of the open-source neuroimaging software. Read the preprint to discover what's new arxiv.org/pdf/2501.12081 and download SPM for free from Github github.com/spm/spm/rele...