Now out in PNAS with @jaeyoungson.bsky.social, Alice Xia, @apaxon.bsky.social & @orielf.bsky.social. Medial temporal lobe encodes predictive representations of people's real-world social networks which afford them key advantages in social navigation. www.pnas.org/doi/10.1073/... 🧵

#ComplexityThoughts is read by 3,400+ readers! This week, I’ve been mapping recent results in complexity science across disciplines, from biochemistry to neuroscience, from evolution to human behavior #80 👉 open.substack.com/pub/manlius/... Available as a “deep-dive” 🎧 on Spotify & Apple

Last reminder: This is happening this Thursday.

I’m very glad to be speaking next week at the AI-Phi session at Sony CSL Paris (@sonycsl-paris.bsky.social). In this Causerie session, I’ll talk about how what we see as valuable can change depending on our goals, and why this matters for learning and decision-making in both humans and AI.

Hi folks, reminder that this is happening next Thursday.

Structure-function coupling in the human brainstem https://www.biorxiv.org/content/10.64898/2026.04.05.716603v1

Wanna infer causal interactions during brief, transient neural events? 🧠⚡ Many methods struggle with such non-stationarities, but we got a robust solution for you! 📦 My recent publication with @cmc-lab.bsky.social 🥳: TranCIT: Transient Causal Interaction Toolbox 📜 JOSS: bsky.app/profile/joss...

If Dante were writing today, I suspect he would place social media somewhere in Malebolge, the eighth circle of the Inferno, among the fraudulent. In this #ComplexityThoughts I discuss the architecture of attention and the content creator economy: manlius.substack.com/p/the-infern...

The LNM debate keeps developing. www.nature.com/articles/s41... @andrewzalesky.bsky.social @natneuro.nature.com #neuroskyence

Our new paper on brain networks engaged during imagining is out now in Neuron! Here is a download link (free for 50 days): authors.elsevier.com/c/1msNE3BtfH... Congratulations to Nate Anderson for leading this work @rementurus.bsky.social 🧵

For more than a century, the study of brain lesions has been central to understanding cognitive processes and normal brain function (e.g., Broca’s studies). However, what electrophysiological signatures emerge following a brain lesion?

G'day connection makers. On **April 16th**, we're hosting Georg Northoff telling us about intrinsic timescales. If it sounds interesting, here's the link to register: cam-ac-uk.zoom.us/meeting/regi...

Inspired by Edinburgh’s legacy of big ideas (e.g., Hume), on a train leaving the city, I crafted a proposal for a book about big ideas in network neuroscience—how brain activity flows generate representations that together compose our minds. The rest is history, and this new book: shorturl.at/3p100

Stimulus-Driven Leakage in Naturalistic Neuroimaging: "It results in spurious predictive performance due to overfitting to repeated signals, even in the presence of independent noise." www.biorxiv.org/content/10.1... uh-oh

What makes brains (un)conscious? We provide new answers—and a universal mammalian blueprint for information processing—in a cross-species study of humans, macaques, marmosets & mice. Exploring convergent breakdown of integration in: www.nature.com/articles/s41... Led by @loopyluppi.bsky.social

Yesterday, we officially relaunched! A massive thank you to everyone who joined us for this first event, and to our terrific speakers Petra Vértes, Sebastian Ahnert and George Cantwell. We've got an unmissable line-up of sessions coming very soon. Stay tuned!

UKgov publishes new screen time guidance for under 5s 👨‍🍼 <2s: Avoid screens except shared activities 👶 2-5s: Try for less than 1hr a day 📱 Choose safe, slow-paced content 🧑‍🧒‍🧒 Lead by example 🛌 Have screen-free areas/times Glad to have contributed. Parent guidance and research report linked below.

Science would be so much better if we did review (of grants and papers) constructively and collaboratively, instead of only using them to produce binary accept/reject decisions. To do that, we have to separate review processes from decisions. One idea for grants 👇

You have to stop whatever you’re doing and pay 150% attention if the font is comic sans

"We are watching two disciplines trade their worst habits. Neuroscience is mistaking benchmarked prediction for understanding, and machine learning is mistaking mechanistic language for mechanism. ..."

Eid-e Nowrooz Mobarak to everyone celebrating

Really stoked to see this project in (pre)print. On how to implement normalization-via-inhibition in ANNs, and what it might mean for inhibition in the brain. ⚖️ Great job @royeyono.bsky.social and the team 👏👏👏

Out in @elife.bsky.social: Functional connectivity-based attractor dynamics of the human brain in rest, task, and disease doi.org/10.7554/eLif...

Clarifying the conceptual dimensions of representation in neuroscience — a Perspective by Stephan Pohl, Edgar Y. Walker, David L. Barack, Jennifer Lee, Rachel N. Denison, Ned Block, Florent Meyniel & Wei Ji Ma www.nature.com/articles/s41...

I’m excited to share my newest work with @benhayden.bsky.social, and the work I’m most proud of to date, on characterizing semantic coding in single-neuron hippocampal activity in patients with autism during natural language comprehension! www.biorxiv.org/content/10.6...

Had great fun discussing some recent work and the value of toy models in neuroscience last night! Our next workshop will be: * 16.04 * 16-20:30 * At the Crick Sign up (for free) and come along! www.eventbrite.co.uk/e/understand...

📢 New preprint from the lab🧠 ▶️doi.org/10.64898/2026.03.12.710517 What does fMRI connectivity actually reflect at the neural level? The natural intuition is: more neural activity = more connectivity! Using cortical perturbations we show this is not necessarily the case: sometimes less is more! 👇🧵

Every spike has an energy cost, so a priori firing rate ought to tell us how important a message is, not the content of the message. It's easy to decode simple variables from knowing which neurons are currently important. Is this why neuroscientists believe neurons communicate via firing rates? 🤖🧠🧪

Out now in Science: The Truman Show, but with killifishes! "Continuous recording of a vertebrate’s adult life from adolescence until death would provide a complete view into the behavioral architecture of aging." www.science.org/doi/10.1126/...

Organization of neuropeptide systems in the human brain | doi.org/10.1038/s415... Neuropeptides are functionally diverse signaling molecules in the brain and body. @cebric.bsky.social curates an atlas of neuropeptide receptors and relates it to brain function @natneuro.nature.com 🧩 🧠 ⤵️

Happy to share a new preprint from my PhD thesis! “A novel framework for expanding RNNs with biophysical detail to solve cognitive tasks” 🧠💻 📝 www.biorxiv.org/content/10.6... @jonescompneurolab.bsky.social

Folks, this is happening tomorrow.

🚀 We are hiring: a PhD position is available in my lab (gozzilab.it) at @iitalk.bsky.social, Italy. Project: large-scale brain network mapping in behaving mice using functional ultrasound imaging (FUSI). 📅 Deadline: March 31 🔗 tinyurl.com/4jtetxa9 Reshares appreciated 😊

Synaptome architecture shapes regional dynamics in the mouse brain | doi.org/10.1371/jour... How do diverse synapses relate to the spatial patterning of whole-brain dynamics? Justine Hansen explores @plosbiology.org ⤵️

Cambridge Networks Network is back! Come have a chat if you're around. If not, you can follow us on Bluesky or even become a member (check the website). Regardless, we're looking for material to add to our resources section. Let me know if you have any.

Don't miss @maxschwabe.bsky.social's poster this evening (our master's student and presenter awardee 🎉) on decomposing RNN dynamics during naturalistic decision-making! It was a joint work with @armanbehrad.bsky.social and @roxana-zeraati.bsky.social!

Next Thursday (March 19th), at 15 UTC, we host Joana Cabral to tell us more about eigenmodes and resonance decomposition. Read and register here if you'd like to tag along: cam-ac-uk.zoom.us/meeting/regi...

Pardon a scientist analysis of the war but this outlines why there will be ground (special) forces in Iran to remove “18 to 20 canisters" containing ~1000 pounds of highly enriched uranium ...unless IRGC surrenders, which if you know the Shia mindset, they never will www.nytimes.com/2026/03/07/o...

𝗪𝗵𝗮𝘁'𝘀 𝘁𝗵𝗲 𝗿𝗲𝗹𝗮𝘁𝗶𝗼𝗻𝘀𝗵𝗶𝗽 𝗯𝗲𝘁𝘄𝗲𝗲𝗻 𝗺𝗮𝗻𝗶𝗳𝗼𝗹𝗱𝘀 𝗮𝗻𝗱 𝗿𝗲𝗰𝘂𝗿𝗿𝗲𝗻𝘁 𝗻𝗲𝘁𝘄𝗼𝗿𝗸𝘀 𝗶𝗻 𝘁𝗵𝗲 𝗯𝗿𝗮𝗶𝗻? This looks like a must read (suppl material bursting with goodies). #neuroskeyence doi.org/10.1016/j.ne...

I was a bit frustrated that Iranian regime’s role in this war is being minimized and people’s historical struggle is ignored so I made a game for you to be the people and see where your decisions take you instead: kuffmode.github.io/mirage/

Excited to share our latest paper in which we discuss merging theory-and data- driven computational psychiatry in a large transdiagnostic cohort study (N=2400) www.biologicalpsychiatrycnni.org/article/S245... Christopher Pittenger, Godfrey Pearlson @annierhcheng.bsky.social @sobp-org.bsky.social

Last call: this is happening **today at 14:00 UTC**.

Once you get past the first 5 minutes of me bumbling around clearly in need of media training, we settle into a nice groove talking about fitting mechanistic models, ML/AI for neuroscience, underconstrainedness vs. degeneracy, and its potential benefits for biology (plus some good chuckles).

Fast degree-preserving rewiring of complex networks arxiv.org/abs/2401.12047

🛰️ We’re inviting proposals for Satellite Workshops at the #BernsteinConference 2026! 🗓️ Deadline: April 29, 15:00 CEST More information 👉 bit.ly/3OV2BNO #BernsteinNetwork #CompNeuro

Delighted to share this paper led by @hannahmcdermott.bsky.social . We examined dynamics of prediction effects (sharpening vs dampening) and found they’re completely different across time scales!

It has been argued that what sets model organisms apart from other experimental 🐋🌱 is their high representational power. In our latest 📃, we argue otherwise: the hallmark of MOs lies in the dimensions of modeling versatility they afford to scientists 👇 link.springer.com/article/10.1... #philsci #HPS

This is happening tomorrow, and again, mind the -1 hour time shift.

I couldn't find a tool to plot different #neuroimaging data in one consistent style, so I made one! Meet yabplot (yet another brain plot) - a #Python package for (sub)cortex & tracts.🧠 - Simple API - Built-in atlases - Custom atlas support 🔗 github.com/teanijarv/ya... (drop a ⭐️!)