ft. @yeqiaoz.bsky.social, N. Burget, Tobias Friedrich, @faryabi.bsky.social (@pennpathlabmed.bsky.social), @atishayjay.bsky.social (Bioeng), S. Yoon & @vahedilab.bsky.social (@penngenetics.bsky.social) @pennepigenetics.bsky.social @i3h-upenn.bsky.social www.nature.com/articles/s41...

ft. M. Abedi, P. Rai, Y. Zhou, C. Liu, I. Johnson, A. Chandra, M. Fasolino, S. Rostami, W. Wang, Z. Min, Y. Li, M. Yu, @atishayjay.bsky.social, V. Lian, M. Silverman, @kkaestner.bsky.social, A. Naji, B. Faryabi & @vahedilab.bsky.social @penngenetics.bsky.social www.science.org/doi/10.1126/...

I am very excited to share our collaborative work on multiome profiling of gene expression and chromatin accessibility of more than 1 million immune cells in pancreatic lymph nodes and spleens in human type 1 diabetes in @sciimmunology.bsky.social scim.ag/4o12TOZ

Lineage-determining transcription factors (EBF1 TCF1) radially position enhancers within gene loci to enable multi-enhancer regulation of key oncogenes @ single-allele level @natcellbio.nature.com @pennmedicine.bsky.social @atishayjay.bsky.social @vahedilab.bsky.social www.nature.com/articles/s41...

Beyond excited to share the collaborative work with @faryabi.bsky.social led by stars Yeqiao Zhou and @atishayjay.bsky.social; Walking along thousands of chromosomes has shown us just how essential it is to measure chromatin fiber geometry to truly understand enhancer biology. tinyurl.com/2st3afwf

Three new manuscripts from Faryabi and Vahedi labs on chromatin folding, ORCA, oncogene regulation and T1D immunology. Individually great, collectively unstoppable. @faryabi.bsky.social @vahedilab.bsky.social @atishayjay.bsky.social tinyurl.com/4nwfbeu2 tinyurl.com/4zaw5cn7 tinyurl.com/25snbf4j

🚨 New #preprint alert! We're excited to share the latest work from the brilliant Sora Yoon: "Inference of multi-enhancer interactions in T lymphocytes using Hi-Cociety"🔗 www.biorxiv.org/content/10.1...

Congrats to Atishay and Carlos for their review article on the epigenetics regulation of T cells: www.nature.com/articles/s41...