Yeqiao Zhou
@yeqiaoz.bsky.social
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📥 24
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Three new manuscripts from Faryabi and Vahedi labs on chromatin folding, ORCA, oncogene regulation and T1D immunology. Individually great, collectively unstoppable.
@faryabi.bsky.social
@vahedilab.bsky.social
@atishayjay.bsky.social
tinyurl.com/4nwfbeu2
tinyurl.com/4zaw5cn7
tinyurl.com/25snbf4j
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OLIVE provides rapid visualization and analysis of chromatin tracing experiments
Zhou et al. develop the optical looping interactive viewing engine (OLIVE), a web-based application for browsing and exploring user-generated and publicly available chromatin tracing datasets.
https://www.cell.com/cell-reports-methods/fulltext/S2667-2375(25)00245-0
7 days ago
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Three new manuscripts from Faryabi and Vahedi labs on chromatin folding, ORCA, oncogene regulation and T1D immunology. Individually great, collectively unstoppable.
@faryabi.bsky.social
@vahedilab.bsky.social
@atishayjay.bsky.social
tinyurl.com/4nwfbeu2
tinyurl.com/4zaw5cn7
tinyurl.com/25snbf4j
loading . . .
OLIVE provides rapid visualization and analysis of chromatin tracing experiments
Zhou et al. develop the optical looping interactive viewing engine (OLIVE), a web-based application for browsing and exploring user-generated and publicly available chromatin tracing datasets.
https://www.cell.com/cell-reports-methods/fulltext/S2667-2375(25)00245-0
7 days ago
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reposted by
Yeqiao Zhou
Golnaz Vahedi
7 days ago
Beyond excited to share the collaborative work with
@faryabi.bsky.social
led by stars Yeqiao Zhou and
@atishayjay.bsky.social
; Walking along thousands of chromosomes has shown us just how essential it is to measure chromatin fiber geometry to truly understand enhancer biology.
tinyurl.com/2st3afwf
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Lineage-determining transcription factors constrain cohesin to drive multi-enhancer oncogene regulation - Nature Cell Biology
Zhou, Jay et al. report that in mantle cell lymphoma and T cell leukaemia, lineage-determining transcription factors share a mechanism to regulate how multiple enhancers control oncogene expression th...
https://www.nature.com/articles/s41556-025-01827-2
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reposted by
Yeqiao Zhou
Golnaz Vahedi
13 days ago
I am very excited to share our collaborative work on multiome profiling of gene expression and chromatin accessibility of more than 1 million immune cells in pancreatic lymph nodes and spleens in human type 1 diabetes in
@sciimmunology.bsky.social
scim.ag/4o12TOZ
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Joint profiling of gene expression and chromatin accessibility in pancreatic lymph nodes and spleens in human type 1 diabetes
Joint chromatin accessibility and transcriptomic profiling of human and mouse pancreatic lymph nodes uncovers distinct features of CD4 T cells in T1D.
https://scim.ag/4o12TOZ
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