🧪 The registration deadline for the First #PANVIRIDE Antiviral Drug Discovery Conference in Gizzeria Lido, Italy, has been extended! Here: lnkd.in/d6dnB8cc Don’t miss the opportunity to share your work, connect with peers, and showcase your research in a high-impact venue.

🧪 We are delighted to present this #Wiley #Special #Collection inspired by two #international #conferences which debuted this year: 📍The First International Conference on Anti-Infectives 2025 in Saarbrücken, Germany 📍The First #PANVIRIDE Antiviral Drug Discovery Conference in Gizzeria Lido, Italy

🧪Complex diseases don’t work like broken clock that can be fixed by replacing a single part As an alternative to the reductionist approach, we present a #multitarget #polypharmacological strategy to reduce drug #burden & prevent pulmonary #exacerbations in #CF www.sciencedirect.com/science/arti...

🧪 In this work, we challenged ourselves to look beyond conventional #Antiviral #Drug #Discovery approaches, exploring an #evolution-#inspired strategy rooted in #prebiotic #chemistry. It’s been an exciting journey of creativity, curiosity, and collaboration. www.nature.com/articles/s41...

🧪This event, held in Catanzaro (Italy) on September 30 2025, will be focused on innovative #antiviral #DrugDiscovery #strategies. To view the full program, register and submit an abstract, visit: 👉 lnkd.in/d6dnB8cc 📅 Registration deadline: July 25, 2025 📧 For further information: [email protected]

The #PANVIRIDE team from the Università degli Studi di Parma. 🧪 A #multidisciplinary effort towards new Broad-Spectrum Antivirals ( #BSAs).💊 Learn more about our mission, research, and Partners on our official website: 🔗 panviride.eu www.linkedin.com/feed/update/...

This is one of the reasons why #peer #review for Scientific Journals should not be treated as an unpaid service, but rather recognized and compensated as a highly professional fee-based activity.

The interactions of droplets or water can spark flashes of electricity - microlightning - which would have provided enough energy to create the key organic molecules needed for life to emerge www.newscientist.com/article/2472...

Take a look at 'Late-stage functionalization of the 4-amino-2-pyridone chemotype using electrochemical and MCR approaches' From @marcoradi.bsky.social and first author Lisa Giannessi.

The Role of ATP Hydrolysis and Product Release in the Translocation Mechanism of SARS-CoV-2 NSP13 https://www.biorxiv.org/content/10.1101/2023.09.28.560057v1

The new issue of #ChemMedChem (@chemistryeurope.bsky.social) is out! chemistry-europe.onlinelibrary.wiley.com/toc/18607187...

The new perspective from the @euromedchem.bsky.social Best Practice Initiative is now online: chemistry-europe.onlinelibrary.wiley.com/doi/abs/10.1... Best practice recommendations for the optimization from a Hit to a Lead. Kudos to Bob Young & Jean Quancard for driving this initiative!

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An excellent perspective on different classes of #helicase #inhibitors 🧪 pubs.acs.org/doi/10.1021/...

Nature is asking for information about how your research is being affected by recent actions. Link is in article below. 🧪 www.nature.com/articles/d41...

A big loss and very bad sign for NIH, folks

The sound of silence 🧪

Best thing I did so far....

“...to care is an act not of weakness, but of strength.” The Lancet response: bit.ly/4jRb5Av

🧪Have you ever wondered whether targeting #PI4KB and #Src / #Abl host kinases could be the next big thing in broad-spectrum #antiviral strategies? 🧐 Well, so did we! But instead of just wondering, we dug deep into the literature and wrote a whole review about it www.sciencedirect.com/science/arti...

A detailed look at fresh samples taken from asteroid Bennu confirms that organic chemistry (and the molecules of life) are everywhere:

Great overview of formulations fundamentals for medicinal chemists from Drug Hunter. drughunter.com/resource/the...

Via @dereklowe.bsky.social: I fear that we are about to enter a Lysenko-like era for American science. Can only hope that our privately funded organizations can keep doing good science, ride out this dark age and be able to pick up when the dust settles. www.science.org/content/blog...

“It sounds like someone trying to sell a new car model by pointing out that its windows roll up and down much more quickly”

This is an impressive application of ML to drug discovery. chemrxiv.org/engage/chemr...

🧪Broad-spectrum #antivirals💊 to fight emerging acute #infections and #coinfections are highly needed www.who.int/emergencies/...

🧪I'm looking forward to see what a #PCSK9 transcription inhibitor can do on breast #cancer #metastasis and we have nice tools💊 for that: www.sciencedirect.com/science/arti....

#Dostarlimab has been granted the breakthrough therapy designation for rectal #cancer 🧪 newatlas.com/cancer/cance...

The Radi Lab 🧪 goes on vacation! 🎄🎉

Targeting #Nsp14 as a promising pan-coronavirus strategy. 🧪

The recombinant SARS-CoV-2 variant XEC is spreading globally and may become dominant, but current vaccines are expected to provide protection against severe disease. ja.ma/41Hbizz

Empowering Youth, Building Tomorrow #Parma Proud to work in such an Amazing city

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Dengue virus transmission in Italy: historical trends up to 2023 and a data repository into the future www.nature.com/articles/s41...

A single Gln226Leu #mutation can completely switch bovine H5 HA to human-type receptor specificity. #Influenza #H5N1

DiffDock, a new diffusion-based ligand docking program, made s big splash earlier this year. But it’s apparently not all it’s claimed to be:

Another outbreak of... something. Very little information available so far, little testing resources in the area and unspecific symptoms, so this could be anything. The extent of spread would be rather large for a novel zoonosis, so my guess at this point is a known pathogen. Still a bit worrying.

#JustPublished! ECDC: wastewater #poliovirus detections in the EU call for continued strong surveillance and high vaccination coverage rates. Read full statement: bit.ly/49fIyQ9 #Polio #cVDPV2

Saturday night fever...🕺

Excellent #echem starter pack 🧪

A very interesting study on how JNJ-A07 can also reduce #DENV transmission by mosquitoes www.science.org/doi/10.1126/... cen.acs.org/pharmaceutic...

Application of cryo-EM to solve the inactive strutture of #CCR6 bound to small-molecule #allosteric #inhibitors 🧪💊 www.nature.com/articles/s41...

Can we exploit the #ESCRT pathway to develop new broad-spectrum #antivirals ? Let’s see where this new adventure will take us 🧪

I'm so proud of this paper and its cover that I just can’t leave it sitting on the other side...😉 #Electrochemistry & #Multicomponent Late-Stage Functionalization ( #LSF) of anti- #PCSK9 drug candidates. 🧪 #GreenChemistry pubs.rsc.org/en/content/a...

Nice and easy 🧪

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Sanfelice et al (2024) The Chemical Probes Portal – 2024: update on this public resource to support best-practice selection and use of small molecules in biomedical research. Nucleic Acids Research 2024 1–7 #ChemBiol #biochem #OpenScience #OpenAccess #chemsky 🧪 doi.org/10.1093/nar/...