Kristina
@kristina-keuper.de
๐ค 62
๐ฅ 122
๐ 21
Scientific Consultant ๐งช
#AI
#sustainability
#datascience
#cancerscience
pinned post!
๐ ๐๐ฑ๐๐ฎ๐ป๐ฐ๐ถ๐ป๐ด ๐ฆ๐๐๐๐ฎ๐ถ๐ป๐ฎ๐ฏ๐น๐ฒ ๐ฅ๐ฒ๐๐ฒ๐ฎ๐ฟ๐ฐ๐ต ๐ฎ๐ป๐ฑ ๐๐ป๐ป๐ผ๐๐ฎ๐๐ถ๐ผ๐ป ๐๐ถ๐๐ต ๐๐ & ๐๐ฎ๐๐ฎ ๐ฆ๐ฐ๐ถ๐ฒ๐ป๐ฐ๐ฒย ๐ Iโm excited to officially introduce my business, dedicated to delivering innovative AI and data science solutions that drive progress in biological research and industry applications. โฆ
4 months ago
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youtu.be/TEGAQxg1gV
Are you ready for this? I am.
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The Building Blocks of AI | Open a World of Endless Possibilities With Tokens
YouTube video by NVIDIA
https://youtu.be/TEGAQxg1gVA
17 days ago
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Here is the latest paper from my stay in ๐ฉ๐ฐDenmark
shorturl.at/gOBCW
The paper investigates how topoisomerase I inhibitors induce stepwise DNA damage and repair over time, depending on dose and exposure duration, to optimize chemotherapy regimens. ๐งช
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Stepwise DNA damage and repair mechanisms at replication forks in response to topoisomerase I inhibition
Camptothecin (CPT) and its derivative irinotecan inhibit DNA topoisomerase I (TOP1), inducing replication stress by stabilizing the TOP1 cleavage compโฆ
https://shorturl.at/gOBCW
18 days ago
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Advanced AlphaFold 3 workshop coming! ๐งช๐พ For those ready to tackle pulldown analysis & get technical (yes, programming required). Join the waitlist:
mailchi.mp/6ff79a3ca8ca...
Original workshop still available for beginners!
#AlphaFold
#Bioinformatics
#StructuralBiology
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19 days ago
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๐งช๐ฏ Next AI webinar - YOU decide the topic! Vote now:
www.kristina-keuper.de/en/you-choose/
Early 2026 | Free webinar
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You choose โ Dr. Kristina Keuper
https://www.kristina-keuper.de/en/you-choose/
24 days ago
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Everybody has a Grinch in the lab... Automate the boring stuff or predict stuff and reclaim your time! ๐งช Your hacks?
#Nikolaus
#LabAutomation
30 days ago
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๐งช๐คWill this "Lifespan of Assistance" be a public utility available to all, or a luxury subscription for the few? In my role as Scientific Consultant, I advocate for AI literacy for everyone. We need to understand these tools to democratize them. What do you think?
#AI
#BioTech
#Ethics
#FutureTech
about 1 month ago
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This fall, rethink how biology gets done. ๐งช๐งฌ In todayโs fast-paced scientific landscape, efficiency is a necessity. Join me for this seminar and build a strong toolbox! Register here:
tinyurl.com/2vdk2tfn
#ResearchEfficiency
#ProteinPrediction
#LiteratureManagement
#ScienceCommunication
3 months ago
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Have a look at my newest Workshop! The first Video is online now. It is about
#alphafold3
and how it helps scientists to achieve more meaningful results faster. This video, as well as the whole workshop is available in English and German.
youtu.be/hJCAqh_DVFI
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AlphaFold 3 Workshop for Beginners - Structure Prediction without Coding
YouTube video by Kristina Keuper
https://youtu.be/hJCAqh_DVFI
3 months ago
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๐ ๐๐ฑ๐๐ฎ๐ป๐ฐ๐ถ๐ป๐ด ๐ฆ๐๐๐๐ฎ๐ถ๐ป๐ฎ๐ฏ๐น๐ฒ ๐ฅ๐ฒ๐๐ฒ๐ฎ๐ฟ๐ฐ๐ต ๐ฎ๐ป๐ฑ ๐๐ป๐ป๐ผ๐๐ฎ๐๐ถ๐ผ๐ป ๐๐ถ๐๐ต ๐๐ & ๐๐ฎ๐๐ฎ ๐ฆ๐ฐ๐ถ๐ฒ๐ป๐ฐ๐ฒย ๐ Iโm excited to officially introduce my business, dedicated to delivering innovative AI and data science solutions that drive progress in biological research and industry applications. โฆ
4 months ago
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Kristina
Tassos Perrakis
about 1 year ago
Surely you have been using AlphaFold3 for your research project? If so, have you considered
#AlphaBridge
to analyze the output for macromolecule complexes prediction? Web server:
alpha-bridge.eu
Preprint:
www.biorxiv.org/content/10.1...
New features coming soon!
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Stand Up for Science!
10 months ago
TODAY IS THE DAY! ๐งชโ๏ธโฌ๏ธ Join us at the Lincoln Memorial or your local site to Stand Up for Science!
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Kristina
๐ฆ Gourdon Lab ๐ฆ ๐ฌ
11 months ago
๐๐งช Super interesting paper from the Sanz-Moreno group showing that the
#ECMatrix
influences
#tumour
#dissemination
, with distinct
#structure
in different tumour regions that then affect
#invasion
patterns.
#cancer
#metastasis
#mechanosensing
#mechanoregulation
www.nature.com/articles/s41...
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Matrix mechano-sensing at the invasive front induces a cytoskeletal and transcriptional memory supporting metastasis - Nature Communications
Interactions with the extracellular matrix (ECM) control tumor proliferation, invasion and metastasis. Here, authors provide spatial information on ECM organization and how it influences tumor cell in...
https://www.nature.com/articles/s41467-025-56299-7
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I am happy to share my latest scientific contribution published in the EMBO Journal. ๐งช
#aneuploidy
#cancer
doi.org/10.1038/s443...
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Proteogenomic analysis reveals adaptive strategies for alleviating the consequences of aneuploidy in cancer | The EMBO Journal
imageimageAneuploidy is frequent in cancer, but in vitro it triggers multiple cellular stresses and often delays proliferation. Through integrative proteogenomic analysis of evolved aneuploid cell lin...
https://doi.org/10.1038/s44318-025-00372-w
11 months ago
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It is relevant to stay updated on this even if you are not a US scientist. What is happening in the US could happen anywhere under certain conditions and it will affect the world wide scientific output, and overall progress in many research areas in the coming years ๐งช
www.science.org/content/blog...
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What's Happening Inside the NIH and NSF
https://www.science.org/content/blog-post/what-s-happening-inside-nih
11 months ago
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Kristina
WHO
11 months ago
Today is
#WorldCancerDay
. Here are some ways to reduce your
#cancer
risk: ๐ญ Donโt use tobacco
#NoTobacco
๐ Exercise regularly ๐ฝ Eat more fruits and vegetables โ Maintain a healthy weight ๐ท Limit alcohol consumption Let's beat cancer!
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Lorenz Adlung
11 months ago
๐ In Mรคusen hemmte die Transplantation der verรคnderten Fettzellen das Tumorwachstum bei Brust- und Bauchspeicheldrรผsenkrebs. ๐ค๐ฅ Ein ultra-spannender Ansatz, um den Stoffwechsel von Krebszellen gezielt anzugreifen! ๐
www.nature.com/artic...
๐งช ๐ Mehr dazu bei
@AdlungLab.com
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Implantation of engineered adipocytes suppresses tumor progression in cancer models
Nature Biotechnology - Adipose manipulation transplantation can reduce tumor growth and proliferation in vitro and in mouse models.
https://www.nature.com/articles/s41587-024-02551-2
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Kristina
Nature Biotechnology
12 months ago
Quantum-computing-enhanced algorithm unveils potential KRAS inhibitors
go.nature.com/3EitbLm
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Quantum-computing-enhanced algorithm unveils potential KRAS inhibitors - Nature Biotechnology
A hybrid model combines quantum and classical approaches to generate compounds targeting the KRAS protein.
https://go.nature.com/3EitbLm
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Kristina
Nature Reviews Bioengineering
11 months ago
Non-invasive hormone monitoring with a wearable sweat biosensor
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Non-invasive hormone monitoring with a wearable sweat biosensor
Nature Reviews Bioengineering, Published online: 31 January 2025; doi:10.1038/s44222-025-00276-8Wearable sweat biosensors enable the non-invasive, real-time monitoring of hormones. Here, we highlight the development and commercialization of a wearableโฆ
https://www.nature.com/articles/s44222-025-00276-8?utm_source=bluesky&utm_medium=social&utm_campaign=natrevbioeng
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Kristina
Atanas G. Atanasov
11 months ago
๐จ Big developments in cancer research! ๐ฏ Neoantigens are revolutionizing cancer vaccines, making treatments smarter & more personalized. Explore how this could transform healthcare ๐ ๐
inpst.net/the-landscap...
๐
#CancerResearch
#Innovation
#INPST
#CRBIOTECH
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Kristina
Scott McGrath
12 months ago
๐งช New data from 2M+ people reveal GLP-1 drugs like Ozempic lower risks for heart disease, stroke, Alzheimerโs, and addiction. However, they raise arthritis risk by 11% and pancreatitis risk by 146%. ๐ฉบ ๐ [soft paywall] Study linked below.
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Obesity drugs: huge study highlights new health risks
Weight-loss medicines such as Ozempic might raise a personโs likelihood of developing conditions including arthritis.
https://www.nature.com/articles/d41586-025-00173-5
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Kristina
eLife
12 months ago
Age-related changes in certain cells that could be driving some breast cancers offer potential screening and prevention targets.
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Aging cells, rising risks
Age-related changes in breast luminal epithelial cells may drive some breast cancers and offer potential screening and prevention targets.
https://elifesciences.org/digests/95720/aging-cells-rising-risks?utm_source=bluesky&utm_medium=social&utm_campaign=organic
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Kristina
Atanas G. Atanasov
12 months ago
๐ Postdoctoral Research Associate open position in comparative genomics and bioinformatics (University of Cambridge) ๐
digitalpatientsafety.com/jobs/
๐
#DHPSP
#INPST
#MolecularMedicine
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Kristina
Nature Cell Biology
about 1 year ago
โThis year, in our
#CellDeath
focus: Glover, Schreiner, Dewson & Tait reviewed the intersection of
#mitochondria
and cell death.
#pyroptosis
#ferroptosis
#necroptosis
#apoptosis
๐https://rdcu.be/d46gt
www.nature.com/articles/s41...
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Mitochondria and cell death - Nature Cell Biology
Several processes of regulated cell death engage or use mitochondria, which are thus central hubs that not only coordinate cell death but also elicit non-lethal signalling mediated by mitochondrial ou...
https://www.nature.com/articles/s41556-024-01429-4
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Kristina
Prof Sam Illingworth
about 1 year ago
๐งช๐ฐ๏ธ Why Cancer Risk Drops After 80 As we age, stem cells lose their ability to growโincluding cancerous growth. A new study links this to older cells acting like they lack iron Targeting this process might improve lung health & cancer therapies ๐
www.nature.com/articles/s41...
#Health
#SciComm
๐งช
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Ageing limits stemness and tumorigenesis by reprogramming iron homeostasis - Nature
Studies using mouse models of lung adenocarcinoma identify an association between age, iron homeostasis and tumour initiation potential that involves NUPR1 and lipocalin-2.
https://www.nature.com/articles/s41586-024-08285-0
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Kristina
Nature Portfolio
about 1 year ago
One of the biggest questions we get is when will our journals be here. We thank you for your patience. You can now follow our journals with this starter pack!
add a skeleton here at some point
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Kristina
eLife
about 1 year ago
The path we take while walking on rugged terrain can be mathematically predicted. ๐
https://buff.ly/4fr7pC1
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Kristina
Our World in Data
about 1 year ago
Almost every new car sold in Norway is electric
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Kristina
Carsten Schulte
about 1 year ago
If you are searching for a PhD opportunity in cellular mechanobiology, this might be for you ๐! The call is still open:
add a skeleton here at some point
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Interesting article bridging metabolism and DNA replication in cancer biology ๐งช
www.nature.com/articles/s42...
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Glucose limitation protects cancer cells from apoptosis induced by pyrimidine restriction and replication inhibition - Nature Metabolism
Nam et al. show that limited glucose availability similar to the tumour microenvironment confers resistance against chemotherapeutic drugs that target DNA synthesis.
https://www.nature.com/articles/s42255-024-01166-w
about 1 year ago
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Kristina
Our World in Data
about 1 year ago
Nearly half of teenagers globally cannot read with comprehension
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Kristina
Chemjobber
about 1 year ago
This is bonkers chemsky ๐งชโ๏ธ
add a skeleton here at some point
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Kristina
Giorgia Quadrato
about 1 year ago
We're excited to share our comprehensive protocol for generating human cerebellar
#organoids
, addressing the many requests we've received from the scientific community! Congratulations to Alex Atamian,
@marcellabirtele.bsky.social
, and Negar Hosseini!
rdcu.be/d13Zu
@natureportfolio.bsky.social
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Generation and long-term culture of human cerebellar organoids from pluripotent stem cells
Nature Protocols - Generation and long-term culture of a human pluripotent stem cell-derived human cerebellar organoid model, which successfully replicates the cellular diversity of the fetal...
https://rdcu.be/d13Zu
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Kristina
Andrew Holding
about 1 year ago
Already have so many ideas I want to try this method on.
add a skeleton here at some point
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Kristina
abgeordnetenwatch
about 1 year ago
Lobbyspenden an Parteien verbieten ๐ hier Petition zeichnen:
www.abgeordnetenwatch.de/kampagnen/pe...
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Unternehmensspenden an Parteien verbieten, Privatspenden deckeln! | abgeordnetenwatch.de
https://www.abgeordnetenwatch.de/kampagnen/petitionen/unternehmensspenden-an-parteien-verbieten-privatspenden-deckeln
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Kristina
Nature Portfolio
about 1 year ago
Coffee consumption is associated with the presence and abundance of a specific member of the human gut microbiome, Lawsonibacter asaccharolyticus, and changes to the plasma metabolome, according to a paper in Nature Microbiology.
https://go.nature.com/3CIl4as
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Throwback to the last camping trip. Captured this moment of a beautiful
#aurora
in southern
#denmark
.
@leon-schoene.de
about 1 year ago
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Kristina
WHO
about 1 year ago
4 Facts about the human papillomavirus (HPV) vaccine: โก๏ธ It protects against HPV - the virus that causes more than 95% of
#CervicalCancer
cases โก๏ธ It has been in use for over 18 years โก๏ธ It is constantly monitored and safe โก๏ธ It is highly effective, even after a single dose
bit.ly/3UUw5f8
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Kristina
Our World in Data
about 1 year ago
We've just made it much easier to reuse the data on Our World in Data! Check out our two new features: enhanced data downloads and the Chart Data API โย both accessible for every one of our charts via the data download button in the lower right corner.
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Peng V. Wu, MD, PhD
about 1 year ago
Happy to be here & share our work on hepatoblastoma - using transcriptomics and patient-derived tumoroids to identify embryonic biliary transcription factor SOX4 as a modifier of Wnt activation & proliferation - published today in
#NatComms
@natureportfolio.bsky.social
www.nature.com/articles/s41...
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A developmental biliary lineage program cooperates with Wnt activation to promote cell proliferation in hepatoblastoma - Nature Communications
Epigenetic causes of intra-tumoural heterogeneity are crucial in paediatric cancers with low mutation rates, such as hepatoblastoma. Here, the authors characterise transcriptional heterogeneity in hep...
https://www.nature.com/articles/s41467-024-53802-4
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Kristina
abgeordnetenwatch
about 1 year ago
Mehr zu den jรผngsten Groรspenden: Spendenflut nach Ampel-Aus - Parteien erhalten Millionen in Rekordzeit
www.abgeordnetenwatch.de/recherchen/p...
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Parteien erhalten Millionen in Rekordzeit | abgeordnetenwatch.de
Mehr als zwei Millionen Euro in nur zwei Wochen: Nach dem Bruch der Ampelkoalition verzeichnen die Parteien einen sprunghaften Anstieg von Groรspenden. Schon jetzt zeichnet sich ein Rekordjahr ab โ au...
https://www.abgeordnetenwatch.de/recherchen/parteispenden/parteien-erhalten-millionen-in-rekordzeit
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Kristina
๐ฆ Gourdon Lab ๐ฆ ๐ฌ
about 1 year ago
Our lab investigates the link between
#obesity
and
#breastcancer
, and the paper below from the von Meyenn group provides valuable insights! ๐งช ๐They show that
#fatcells
remember being biggerโand act like it!
www.nature.com/articles/s41...
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Adipose tissue retains an epigenetic memory of obesity after weight loss - Nature
Stable epigenetic changes indicate the existence of an obesogenic memory in mouse adipocytes that primes cells for pathological responses in an obesogenic environment and potentially contributes to th...
https://www.nature.com/articles/s41586-024-08165-7
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Kristina
Our World in Data
about 1 year ago
The COVID-19 pandemic is estimated to have killed more than 25 million people. It caused grief and suffering among their loved ones, impacted people's health worldwide, & disrupted work & lifestyles. We look back with 17 key charts:
https://ourworldindata.org/key-charts-understand-covid-pandemic
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17 key charts to understand the COVID-19 pandemic
The pandemic has resulted in over twenty million deaths. In this article, we review the key insights from global data on COVID-19.
https://ourworldindata.org/key-charts-understand-covid-pandemic
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Hi everyone! ๐งช Iโm a postdoc at the Danish Cancer Institute, studying DNA replication ๐งฌ and genome integrity and their roles in cancer. I would love to connect with others in the field.
#academicsky
#datasciencesky
#cancersky
#introduction
about 1 year ago
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This is how danish winter looked like last year ๐ฅถ Letโs see how it will be this year.
#denmark
#europe
#wintervibes
Since I live here, I really understand why
#hygge
is so important to the Danes.
about 1 year ago
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Kristina
Beuteltier
about 1 year ago
Ich will, dass wir โHERUMSรDERNโ in den Duden aufnehmen. Fรผr das Gejaule alter weiรer Mรคnner, die immer im Mittelpunkt stehen wollen, sich selbst permanent reden hรถren mรผssen (auch wenn es nur toxischer, populistischer oder irrelevanter Scheiร ist) und die allen gottlos auf die Nerven gehen.
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