Chris Fiscus
@fiscuscj.bsky.social
📤 125
📥 141
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evolutionary geneticist, former postdoc @UCIrvine. Views my own.
https://allmylinks.com/fiscuscj
reposted by
Chris Fiscus
Seema Sheth
1 day ago
Amy Angert and I are recruiting a
#postdoc
to participate in a collaborative NSF-funded study of demographic responses to climate across the geographic range of the scarlet monkeyflower. Please repost!
jobs.ncsu.edu/postings/224...
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This pkg is bussin()
hadley.github.io/genzplyr/
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dplyr but make it bussin fr fr no cap
`genzplyr` is an alternative syntax for `dplyr` that replaces boring old function names with GenZ slang. Your data wrangling is about to hit different.
https://hadley.github.io/genzplyr/
2 days ago
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In
@elife.bsky.social
: The genetic control of rapid genome content divergence in Arabidopsis thaliana
doi.org/10.7554/eLif...
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https://doi.org/10.7554/eLife.108238
18 days ago
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Chris Fiscus
Graham Coop
24 days ago
Congratulations to
@jeffgroh.bsky.social
on the publication of his paper on an ancient balanced polymorphisms controlling heterodichogamy in two genera of wingnuts. The paper shows the putative turnover & reversal of dominance of a mating type polymorphism
www.sciencedirect.com/science/arti...
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Distinct haplotypes and reversed dominance at a single-gene balanced polymorphism controlling heterodichogamy in two genera of wingnuts
In the angiosperm mating system of heterodichogamy, two hermaphroditic morphs temporally alternate between male and female flowering phases, promoting…
https://www.sciencedirect.com/science/article/pii/S0960982225012618?dgcid=coauthor
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Chris Fiscus
Maria Rebolleda-Gomez
23 days ago
Paper is finally out!! Thanks to reviewers we dig deeper on the differences between domestication events -spoiler alert: it doesn't matter that much.
nph.onlinelibrary.wiley.com/doi/full/10....
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Chris Fiscus
Roshni Patel
25 days ago
I'm recruiting a postdoc for my group (based in beautiful Eugene, OR). Please get in touch if you're interested, esp if you'd like to chat at
#ASHG25
!
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Chris Fiscus
Graham Coop
25 days ago
We're excited to be recruiting an NIH funded postdoc to work in the Coop lab at UC Davis. We're specifically interested in candidates who are want to work at the intersection of human genetics, GWAS, and population genetics modeling. Please RT
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Chris Fiscus
Jeffrey Ross-Ibarra
about 1 month ago
PEQG website live!
genetics-gsa.org/peqg-2026/
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Homepage - 2026 Population, Evolutionary, and Quantitative Genetics Conference
Visit our website to learn more.
https://genetics-gsa.org/peqg-2026/
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Chris Fiscus
Mike Wiser
about 2 months ago
I keep trying to get people to recognize that my having a PhD says a lot more about me being stubborn than me being smart.
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Chris Fiscus
Chenxin Li, PhD
2 months ago
Please share! I'm looking for a postdoc. The position is to lead one of the following projects: 1) regulation of plant specialized metabolism by cell fate, or 2) foliar embryogenesis in the succulent plant Kalanchoe. Learn more abt projects:
cxli233.github.io/cxLi_lab/res...
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Plant cells are totipotent, meaning individual cells have the potential to develop into a full organism, a property unique to the zygote for animals. However, in most species for most cells, plant cells are not spontaneously totipotent, since they must be treated with specific hormone combinations to unlock their totipotency. Species within the Kalanchoe genus is unique as they spontaneously develop foliar embryos that are fully realized plantlets with shoot and root from notches along the edges of leaves. We speculate that the progenitor cells that give rise to these foliar embryos are totipotent, and we are using single cell techniques to identify & characterize them. In addition to being a fundamental process for plant biology, we foresee unlocking totipotency has many biotechnological applications, such as faciliating genetic transformation and the development of synthetic organs of biomanufacturing.
https://cxli233.github.io/cxLi_lab/research
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Chris Fiscus
Haky Im
about 2 months ago
I'm hiring a computational biologist interested in complex trait genetics using deep learning approaches. Reach out to me, if interested.
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Chris Fiscus
Casey terHorst
2 months ago
The GRFP lives!! (due end of October)
www.nsf.gov/funding/oppo...
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NSF Graduate Research Fellowship Program (GRFP)
https://www.nsf.gov/funding/opportunities/grfp-nsf-graduate-research-fellowship-program
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Opinion | Students Hate Them. Universities Need Them. The Only Real Solution to the A.I. Cheating Crisis.
https://www.nytimes.com/2025/08/26/opinion/culture/ai-chatgpt-college-cheating-medieval.html?unlocked_article_code=1.jE8.oaDz.lgJcd6rBQmUz&smid=url-share
2 months ago
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Chris Fiscus
Tanja Slotte
2 months ago
*Postdoc in Evolutionary genomics at Stockholm University* We are recruiting a postdoc for a large interdisciplinary project to investigate evolutionary drivers and genomic consequences of pollen evolution in response to pollination mode shifts in flowering plants. 1/5
su.varbi.com/what:job/job...
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Chris Fiscus
Stephen I Wright
2 months ago
Please share broadly: I am looking for a postdoctoral fellow to work on a collaborative project on the temporal population genomics of invasive Capeweed (using contemporary and herbarium genomics), with @shaky-dingo.bsky.social and colleagues
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@emccnicotiana.bsky.social
@jlandisbotany.bsky.social
any thoughts on this?
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2 months ago
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Chris Fiscus
HerRoyalThighness
3 months ago
Don’t be afraid to share your writing. There are six Sharknado movies.
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Chris Fiscus
PlantEvolution 🌱🌾
3 months ago
Wonderful (and humble) essay on mentorship by Brandon Gaut, on occasion of Brandon receiving the inaugural Mentorship Award of
@genetics-gsa.bsky.social
. I hope this will be widely read!
academic.oup.com/genetics/art...
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Chris Fiscus
Nandita Garud
4 months ago
I am seeking a postdoc for my group at UCLA. We work at the intersection of population genetics x microbiome (
garud.eeb.ucla.edu
). If interested, please message me!
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Garud Lab
https://garud.eeb.ucla.edu
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Chris Fiscus
Kirk Lohmueller
4 months ago
Sad to be missing
#SMBE2025
. But, the lab will be represented with presentations from (all on Wednesday): Swetha Ramesh (at 11:50 in Symp 17, Noncoding) Chenlu Di (at 12:05 in Symp 17, Noncoding) Diana A Gomez (at 15:45 in Symp 19, Con Gen) Aina Mi Zurita (at 16:40 in Symp 22, Theory Adv)
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Chris Fiscus
Dan Sloan
4 months ago
Please share! Our lab is recruiting a PhD student to join us starting fall 2026. Our group is broadly interested in plant molecular evolution and comparative genomics. More info about our lab and grad programs at Colorado St. is available on our lab website.
sites.google.com/site/danielb...
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Sloan Lab
Welcome! Our research focuses on the evolutionary process at the molecular level. In particular, we investigate how a mixture of natural selection and non-adaptive forces create and maintain the amazi...
https://sites.google.com/site/danielbsloan
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Chris Fiscus
Joel Sharbrough
4 months ago
Please RT! I'm hiring a postdoc to work in my new lab at UCSB (!) on an NSF-funded project investigating the phenotypic consequences of WGD for photosynthesis and respiration. Check out the full posting here:
recruit.ap.ucsb.edu/JPF02986
And more info about the lab here:
sharbroughlab.com
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Very cool walkthrough showing how a LLM works… I think I’m going to have to go through this at least 10 more times:
bbycroft.net/llm
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LLM Visualization
A 3D animated visualization of an LLM with a walkthrough.
https://bbycroft.net/llm
4 months ago
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Chris Fiscus
Molecular Biology and Evolution
4 months ago
@galenm.bsky.social
@fiscuscj.bsky.social
@bsgaut.bsky.social
analyzed SNPs altering RNA secondary structure in A. thaliana, finding reduced diversity and allele frequency for these mutations, suggesting purifying selection in UTRs, and lower expression. 🔗
doi.org/10.1093/molbev/msaf126
#evobio
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Quantifying the Evolution of SNPs That Affect RNA Secondary Structure in Arabidopsis thaliana Genes
Abstract. Single-stranded RNA molecules can form intramolecular bonds between nucleotides to create secondary structures. These structures can have phenoty
https://doi.org/10.1093/molbev/msaf126
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Excited to share our new paper in
@molbioevol.bsky.social
, led by
@galenm.bsky.social
!!! We show that mutations affecting RNA secondary structure in *Arabidopsis thaliana* are shaped by selection and linked to gene expression and the environment. 🔗
academic.oup.com/mbe/article/...
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Quantifying the Evolution of SNPs That Affect RNA Secondary Structure in Arabidopsis thaliana Genes
Abstract. Single-stranded RNA molecules can form intramolecular bonds between nucleotides to create secondary structures. These structures can have phenoty
https://academic.oup.com/mbe/article/42/6/msaf126/8159724
5 months ago
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Chris Fiscus
Jeffrey Ross-Ibarra
5 months ago
Happy to see this out!
@reginafairbanks.bsky.social
analysis of perhaps the most famous maize domestication locus, teosinte glume architecture 1, which controls much of the change from the enclosed fruitcase (top) in teosinte to the "naked" grains of maize (bottom)
www.pnas.org/doi/10.1073/...
1/2
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Chris Fiscus
Dan Garisto
5 months ago
Presidential budget is out. Here's NSF. Biggest cut, by amount, is $1 billion, or 66.8%, from MPS (Physics & Math directorate).
nsf-gov-resources.nsf.gov/files/00-NSF...
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Chris Fiscus
Health Nerd
6 months ago
Recently, the head of the FDA - Dr. Marty Makary - said that we should swap insulin for cooking classes to treat diabetes. This is a ridiculous thing to say. Not just because it's insulting, but also because cooking classes don't really work. My new piece:
gidmk.substack.com/p/you-cant-r...
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You Can't Replace Insulin With Cooking Classes
Why cooking classes are a terrible way to stop people from being fat
https://gidmk.substack.com/p/you-cant-replace-insulin-with-cooking
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Our work on the landscape genomics of *Vitis arizonica* is now published in
@newphyt.bsky.social
!!! Big thanks to Jonás Aguirre-Liguori, Garren Gaut, and Brandon Gaut (all sadly not on bsky) for making this possible!
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Mutational load and adaptive variation are shaped by climate and species range dynamics in Vitis arizonica
Genetic load can reduce fitness and hinder adaptation. While its genetic underpinnings are well established, the influence of environmental variation on genetic load is less well characterized, as i.....
https://nph.onlinelibrary.wiley.com/doi/10.1111/nph.70238
6 months ago
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Chris Fiscus
Rebekah Tromble
6 months ago
This is an important read for
#sciencesky
#academicsky
#socialscisky
. But one I don’t recommend if you’re concerned about your blood pressure.
www.whitehouse.gov/briefings-st...
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Remarks by Director Kratsios at the National Academy of Sciences
Remarks by Director Kratsios at the National Academy of Sciences REINVIGORATING AMERICA’S SCIENTIFIC ENTERPRISE AS PREPARED FOR DELIVERY Washington, D.C.
https://www.whitehouse.gov/briefings-statements/2025/05/remarks-by-director-kratsios-at-the-national-academy-of-sciences/
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Chris Fiscus
Kevin Gardner
6 months ago
Outstanding presentation of the devastating cuts at NSF and their impact across multiple areas of scientific research and training. Angry at the impact now and in the long-term to US research.
www.nytimes.com/interactive/...
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Trump Has Cut Science Funding to Its Lowest Level in Decades (Gift Article)
The lag in funding extends far beyond D.E.I. initiatives, affecting almost every area of science: chemistry, computing, engineering, materials and more.
https://www.nytimes.com/interactive/2025/05/22/upshot/nsf-grants-trump-cuts.html?unlocked_article_code=1.JU8.rXCF.D1w4lS2JB4NM&smid=url-share
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Chris Fiscus
Arun Durvasula
6 months ago
Excited to share our work on using pathway-specific polygenic scores to discover gene-environment interactions
www.medrxiv.org/content/10.1...
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Absolutely thrilled to see Dr. Brandon Gaut receive the inaugural
@genetics-gsa.bsky.social
Mentorship Award! 🏆🎉 Brandon brings humanity back to science, supports inclusive training, and pushes back on the publish-or-perish culture. So well deserved—congrats! 👏🙌
genestogenomes.org/distinguishe...
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Distinguished professor proves effective mentorship is both art and science
For the inaugural recipient of the Genetics Society of America Mentorship Award Dr. Brandon Gaut, leading a lab is not only scientific but personal.
https://genestogenomes.org/distinguished-professor-proves-effective-mentorship-is-both-art-and-science/
6 months ago
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Chris Fiscus
Silas Tittes
6 months ago
Come one come all! Come get involved in stdpopsim and help us decide where to go from here!
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Chris Fiscus
Fritz Sedlazeck
6 months ago
Already 30+ registered for our 7th
#bioinformatics
#hackathon
@bcmhgsc.bsky.social
around Structural Variants, Graph genomes & many related topics:
fritzsedlazeck.github.io/blog/2025/ha..
. Groups will work on interesting topics that will be published in F1000. Registration till 10th of Aug!
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Chris Fiscus
Melissa Wilson
6 months ago
Our work looking at the effects of using autosomal assumptions for calling variation on X and Y. We used simulated data to compare to a ground truth. Tldr: Accurate ploidy is important for reducing false positives; appropriate alignment reduces false negatives.
www.biorxiv.org/content/10.1...
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Best practices for improving alignment and variant calling on human sex chromosomes
Sex chromosome complement is the largest karyotypic variation observed in humans. X and Y chromosomes were once a pair of homologous autosomes. Although chromosome X and Y differentiated from one anot...
https://www.biorxiv.org/content/10.1101/2025.04.29.651297v1
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Chris Fiscus
J. Chris Pires
6 months ago
#WithoutNSF
, it will be more challenging to train the next generation of scientists & entrepreneurs in
#agriculture
#Soil
#Crop
#plant
#biology
#genomics
#teamscience
& more;
#NSF
supports training of students & that is in our national interest
#SupportNSF
#SaveNSF
#AgSky
#AcademicSky
#highered
🌾🌱🧪
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Chris Fiscus
Jeremy B. Yoder 🧬📊🌿🏳️🌈🖖🏻
6 months ago
Bears repeating that Congress has not passed a budget or any other legislation that has asked the NSF to do this downsizing, they're dismantling the agency in anticipation of cuts that as of yet have no basis in law
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Dr. David Miller 🏳️🌈
6 months ago
🧪 Ranking member Lofgren and 11 other House dems sent a fiery 7-page letter to acting NSF director today "The cancelation of these awards suggests instead that NSF is willing to apply political censorship of awards under direction from President Trump and the DOGE teenagers" Share widely
#SaveNSF
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https://democrats-science.house.gov/imo/media/doc/2025-05-08%20Letter%20to%20Acting%20Director%20Stone.pdf
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Chris Fiscus
Caitlin S., PhD
6 months ago
Here are
#NSF
education and advocacy talking points.
#SaveNSF
(Shared with permission - CC0; no attribution required)
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Chris Fiscus
Jeffrey Ross-Ibarra
6 months ago
Now out in print! Elli Cryan (coadvised by
@spicybotrytis.bsky.social
) digs deep into the sgtructure and function of hybrid incompatibility loci in maize. Among other things she discovers a conserved, ancient pseudogene haplotype that silences the locus in trans!
academic.oup.com/genetics/adv...
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Chris Fiscus
Laura Turchi (she/her)
6 months ago
⚠️ Super important update of the Arabidopsis reference genome! 👇👇👇
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@emccnicotiana.bsky.social
any idea on this?
add a skeleton here at some point
6 months ago
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Chris Fiscus
Seema Sheth
6 months ago
We begin reviewing applications next week!
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Chris Fiscus
Dr. Arun Sethuraman
6 months ago
Crazy times, but I'll be advertising for a 2 year postdoc to work with me on new comp. methods to estimate evolutionary history soon - specifically to develop methods to handle missing data (e.g. ascertainment bias, allele dropout). Are you a comp. biologist graduating with a PhD soon? Reach out!
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Chris Fiscus
Dan Garisto
7 months ago
In addition to the terminations of existing awards, new NSF grants are still stopped completely since DOGE was granted access to systems a week ago. Last Thursday, an agency spokesperson said "NSF continues to issue awards." That does not appear to be the case.
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