I'm hiring a computational biologist interested in complex trait genetics using deep learning approaches. Reach out to me, if interested.

Check out our scPrediXcan paper www.cell.com/cell-genomic... Led by the talented @Charles_Zhou12 and supervised by @MengjieChen6 and me, with thanks to many contributors. scPrediXcan integrates deep learning and single cell expression data into a powerful cell type specific TWAS framework.

Need a break from doomscrolling? Do you study the genetics of disease subtypes? Have you ever wondered how to efficiently run gene-based associations with multicategorical outcomes? Join us for the IGES Journal Club on Wednesday, February 26, 2025! 11AM ET.

Modern GWAS can identify 1000s of significant hits but it can be hard to turn this into biological insight. What key cellular functions link genetic variation to disease? I'm very excited to present our new work combining associations and Perturb-seq to build interpretable causal graphs! A 🧵

1/At the #HoffmanLab lab meeting, we often have tech talks describing useful tools for other lab members. Since they might also prove useful for others, we've been posting almost every #HoffmanLabTechTalk for years. 🧪🧬💻

check out our new preprint led by Charles Zhou and supervised by Mengjie Chen and me doi.org/10.1101/2024... where we present scPrediXcan which integrates deep learning and single cell expression data into a powerful cell type specific TWAS framework

🆕 Blog: Genomics scientists from and in Mexico community building lcolladotor.github.io/2024/11/11/g... I want our voices🇲🇽 to be heard from the scientific community. But to be heard, we have to be a part of it #LCG-UNAM #LCG-EJ-UNAM @cdsbmexico.bsky.social #NNB-UNAM #RMB youtu.be/OVMw0k6AydA?...

Peter Buxtun, the whistleblower who revealed that the U.S. government allowed hundreds of Black men in rural Alabama to go untreated for syphilis in what became known as the Tuskegee study, has died. He was 86. apnews.com/article/buxt...

IGES (international genetic epidemiology society) journal club recording "The All of Us Research Program: Data Resources and Access"; by Dr. Anji Musick is available here: drive.google.com/file/d/1bty6...

Also worth noting: the US NIH offers financial support for those from ANY underrepresented group at ANY career stage to join an NIH funded lab! Find a professor whose research you’re interested in and see if they are willing to host you! grants.nih.gov/grants/guide...

On the problem of inflation in TWAS Does TWAS yield inflated p-values?

**Job Alert** Our department at UF is hiring a TT assistant professor in Quantitative Methods (open area). See job ad here, and please retweet: psych.ufl.edu/news/2023/as... #PsychSciSky #neurskyence #academicjobs #academia

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