November is Pancreatic Cancer Awareness Month 💜 It’s the deadliest of the common cancers due to late detection. Researchers stress genetic testing - hereditary risk matters. Know your family history. Advocate for early detection. 💜 Read more 👉 shorturl.at/eKuTB #PancreaticCancer #GeneticTesting

We’re proud to present the current Council members of The International Society for Gastrointestinal Hereditary Tumours (InSiGHT), driving progress in research, collaboration, and patient care worldwide. Learn more about us👉 shorturl.at/6cyJV #Genetics #GIHealth #HereditaryGICancer #InSiGHT

We had the 3rd meeting of the UK EOCRC Research Consortium in beautiful Edinburgh yesterday supported by British Society of Gastroenterology (BSG) and @bowelcanceruk.bsky.social attended by over 50 UK academics - celebrating our first project funding success only 1 year after foundation

Diagnostic yield of colonoscopy in Lynch Syndrome We demonstrate a high adenoma burden with distinct phenotypic and gene-specific characteristics in a UK LS population undergoing high quality surveillance fg.bmj.com/content/earl...

Chemo and surgery failed to treat one woman's advanced cancer. Hope emerged through genetic testing, revealing an unexpected cause. https://www.cbsnews.com/news/advanced-ovarian-cancer-molecular-genetic-testing-lynch-syndrome/ 

We are looking for our new Tom Smith Clinical Research Fellow in #LynchSyndrome and Early Onset ColorectalCancer with @trevorgraham.bsky.social in translational science … thanks to 40tude curing colon cancer for supporting this fellowship - get in touch! @stmarksgenomics.bsky.social @icr.ac.uk

📣Missed #CGAIGC25 this year? Catch the short discussion between Prof Sir John Burn & @swatipatelmd.bsky.social sharing long-awaited CaPP3 results, a follow-up to the landmark CaPP2 trial showing aspirin’s 💊role in lowering cancer risk in #LynchSyndrome 👉 tinyurl.com/msshdb5b #HereditaryGICancer

🧬 October = National Family History Month! Read the blog📜👉 tinyurl.com/bdhjjv83 Reminding us that even in the era of🧬testing, 👪history is still the foundation of hereditary cancer care. Asking the right❓& sharing results can save lives across generations. #HereditaryGICancer

Day 3 of Hereditary Cancer Awareness Month 🧬 also highlights Gynecologic Cancer Awareness Month 💜. Watch the video on ctDNA for Endometrial Cancer 🎥 tinyurl.com/3fajahme + listen to our podcast on Lynch syndrome & NCCN updates 🎧 tinyurl.com/2jmvmt7t #HereditaryGICancer #LynchSyndrome

I have been able to connect with other people with Lynch Syndrome, and this has helped me so much, as I felt so alone when I was first diagnosed in 2024.

While the underlying genetic defects differ significantly between Lynch syndrome and FAP, the pathogenetic mechanisms in these two disorders represent canonical pathways of young-onset colorectal cancer carcinogenesis. https://www.nature.c...

Back to London early as today’s my date for ongoing Lynch Syndrome bowel/prostate cancer research project at Royal Marsden. I don’t have the genetic flaw so am part of the control group. Important stuff x

Frank Sinicrope MD of Mayo Clinic Comprehensive Cancer Center will present new subgroup findings from the #ATOMIC trial (Alliance A021502) in a poster session at #ESMO25. Data highlight outcomes in sporadic vs. Lynch syndrome–related dMMR colon cancer. Sunday, Oct 19. @ALLIANCE_org #NCI #NCTN #CRCsm

Low Yield of Genetic Testing in Serrated Polyposis Syndrome journals.lww.com/ctg/fulltext...

Critical Evaluation of Total Neoadjuvant Therapy for Locally Advanced Rectal Cancer | JCO Oncology Practice ascopubs.org/doi/10.1200/...

New study shows COVID vaccines: 💉Reduced people’s risk of ER by 29% 💉Reduced risk of hospitalizations by 39% 💉Reduced the risk of death by 64% 💉Vaccination was effective in all age groups and “in persons with or without major chronic conditions.” www.scientificamerican.com/article/new-...

Excellent op Ed about the issues with single vaccines published in response to Trumps Statement about single shots for Measles, mumps and rubella as well as CDC call for single vaccine manufacturer 🧵🧪#HealthPolicy

Join our free, open access webinar with the Young European Hematology Association & @yefis-immunology.bsky.social, featuring 3 presentations on CAR T-cells! 📅 19 November 14:00-15:30 CET 🌍 Zoom us02web.zoom.us/webinar/regi...

🚨 It’s here! The Scientific Program for InSiGHT 2026 (4–7 March, Singapore 🇸🇬) is now live! 🔗 Check out the full program: insight2026.org/scientific-programme 🧬 Abstracts due 30 Sept – submit yours: insight2026.org/abstract-submission-guidelines #InSiGHT2026 #HereditaryCancer #GICancerResearch

I'm very pleased to announce the official publication of our lab's paper "DNA mutagenesis driven by transcription factor competition with mismatch repair" in today's issue of Cell! www.cell.com/cell/abstrac...

Mary Kennedy's powerful story about bowel screening inspired thousands of others to take action. Her message is simple: even if you feel well, screening can save your life. Read how her story made an impact: tinyurl.com/PPP-story-ca... #ChooseScreening #BowelScreen

Today, we launch #CancerNeedsTrials. Cancer trials give patients access to tomorrow’s treatments today — but in Ireland, access is too limited. We’re calling on the government to invest so more patients can benefit. Add your voice: bit.ly/4nos5iL #CancerNeedsTrials

Our results support universal and paired somatic and germline multi-gene panels for all EOCRC patients, regardless of MMR status or family history onlinelibrary.wiley.com/doi/10.1002/...

Genetic testing appears to have limited utility in SPS patients and may primarily identify those with an incidental diagnosis of Lynch syndrome pubmed.ncbi.nlm.nih.gov/41002021/

So the politicisation of health continues in the States and I want to highlight a few key things 🧪🧵

Doing Cancer Wrong: I have an innate tendency to do precisely the opposite of what society expects from me. adventuresofasickdoctor.blogspot.com/2025/06/doin...

Fantastic piece in Nature Reviews Neuro by @nicolecrust.bsky.social on the importance of science communication. My take? Everything matters - just do something. It will make a difference for how science is valued and trusted, how community understands. Let's get out there and communicate! 👏

Endometriosis is a chronic inflammatory disease in which cells similar to those lining the uterus are present outside of the uterus. This JAMA Patient Page describes endometriosis development, as well as its signs and symptoms, diagnosis, and treatment. ja.ma/3K53fpL

ICYMI: New online! Vaccine for pancreatic and colorectal cancer: phase I AMPLIFY-201 trial

The 2025 Fuel Allowance lump sums are scheduled for the last week of September 2025 and the first week of January 2026. The 2025/2026 Fuel Allowance season begins on Monday, September 22, 2025, and the allowance is paid for 28 weeks.

How do #patents affect #AccessToMedicines? On 🗓️6 November, 16:00–17:30 CET, we invite patient advocates to a dedicated 🖥️webinar on the role of patents in shaping the availability of medicines. Register here➡️ events.zoom.us/ev/ApxG1qgYa... #MakingAccessHappen #DiCE @mepsagainstcancer.bsky.social

If you or a loved one have been diagnosed with #bowelcancer or you're a member of the public who wants to understand more about the disease- risk-factors, diagnosis, treatments, research, advocacy check out this great booklet from @RCSI_Irl 👇 Free to download

Scientists will not find a simple answer to how autism arises, despite Robert F. Kennedy, Jr.’s promise to announce its causes sometime this month. Here’s what makes the condition so staggeringly complex

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