Outcomes from the English National #LynchSyndrome transformation project: New diagnoses of LS have consistently increased each year from a total of 545 in 2020 to a total of 1394 in 2024 (an increase of 255% vs. a target of >50%). onlinelibrary.wiley.com/doi/10.1002/...

Read about our plans to analyse the century long archive at St Mark's Hospital to understand why more young people are being diagnosed with bowel cancer @trevorgraham.bsky.social www-bbc-co-uk.cdn.ampproject.org/c/s/www.bbc....

We’re proud to present the current Council members of The International Society for Gastrointestinal Hereditary Tumours (InSiGHT), driving progress in research, collaboration, and patient care worldwide. Learn more about us👉 shorturl.at/6cyJV #Genetics #GIHealth #HereditaryGICancer #InSiGHT

Diagnostic yield of colonoscopy in Lynch Syndrome We demonstrate a high adenoma burden with distinct phenotypic and gene-specific characteristics in a UK LS population undergoing high quality surveillance fg.bmj.com/content/earl...

@kevinmonahan.bsky.social & I have an open clinical #PhD position between @stmarkshospital.bsky.social and @icr.ac.uk If you're interested in the biology of pre-cancer in the bowel & want to translate biology for cancer prevention this one could be for you... funded by the brilliant #40tude

We are looking for our new Tom Smith Clinical Research Fellow in #LynchSyndrome and Early Onset ColorectalCancer with @trevorgraham.bsky.social in translational science … thanks to 40tude curing colon cancer for supporting this fellowship - get in touch! @stmarksgenomics.bsky.social @icr.ac.uk

We had the 3rd meeting of the UK EOCRC Research Consortium in beautiful Edinburgh yesterday supported by British Society of Gastroenterology (BSG) and @bowelcanceruk.bsky.social attended by over 50 UK academics - celebrating our first project funding success only 1 year after foundation

James D Watson, co-discoverer of the structure of DNA, dies aged 97

Low Yield of Genetic Testing in Serrated Polyposis Syndrome journals.lww.com/ctg/fulltext...

And they’re off! 🏁 👟 Elaine Burns🚶‍♀️Vs Danilo Miskovic 🏃 Our colon cancer workshop is on day 2 of ‘Frontiers’ - run or walk with our experts 🌟 (Must watch video below 👇🏻😜) Sign up to be in with a chance to participate - bit.ly/4ktsvDc @lnwh.bsky.social @kevinmonahan.bsky.social

'Everybody's unique in their own way' - Tadej Pogačar Love this guy - The true #GOAT www.cyclingnews.com/news/everybo...

I'm very pleased to announce the official publication of our lab's paper "DNA mutagenesis driven by transcription factor competition with mismatch repair" in today's issue of Cell! www.cell.com/cell/abstrac...

Can we prevent IBD? We are delighted to have Prof. Johan Burisch as one of our visiting professors for this years Frontiers congress 🙌🏻 Hear more about Prof. Burisch in the video below ⬇️ Register now - bit.ly/4ktsvDc @lnwh.bsky.social @kevinmonahan.bsky.social

Final Call for Abstracts – Deadline Today!⏳ Don't miss your chance to be part of the #InSiGHT2026 Biennial Meeting in #Singapore! 🌏 🗓️ Submission Deadline: 30 September 2025 ⏰ Time: Midnight (Singapore Time) / 6pm CET Submit your abstract now! insight2026.org/abstract-sub... #Genetics #GIcancer

🚨 Final Call: Abstract submissions for #InSiGHT2026 close TOMORROW – Sept 30! Join the global conversation on hereditary GI tumours. Submit now 👉 insight2026.org Let your research drive progress. #MedicalResearch #Genetics #GIcancer #AbstractSubmission

Our results support universal and paired somatic and germline multi-gene panels for all EOCRC patients, regardless of MMR status or family history onlinelibrary.wiley.com/doi/10.1002/...

Genetic testing appears to have limited utility in SPS patients and may primarily identify those with an incidental diagnosis of Lynch syndrome pubmed.ncbi.nlm.nih.gov/41002021/

Cancer is an evolutionary disease, but does knowing a cancer’s evolutionary past help predict its future? Out today in @nature, we learnt the evolution of 2000 lymphoid cancers and found it was highly correlated with clinical outcomes! (1/7) rdcu.be/eFrrc

Lineage tracking using methylation states from longitudinal bulk sampling. Sounds 🆒 and given recent work by @trevorgraham.bsky.social and colleagues, looks real. Wondering about other applications like 🦠🧫 👉🏻News and views: www.nature.com/articles/d41... 👉🏻Paper www.nature.com/articles/s41...

🚨 It’s here! The Scientific Program for InSiGHT 2026 (4–7 March, Singapore 🇸🇬) is now live! 🔗 Check out the full program: insight2026.org/scientific-programme 🧬 Abstracts due 30 Sept – submit yours: insight2026.org/abstract-submission-guidelines #InSiGHT2026 #HereditaryCancer #GICancerResearch

🚀 Exciting news! We’re launching Young-Insight for InSiGHT members under 40. Join our first meeting to share ideas & shape the future of our community. Email [email protected] with subject “Young Insight” to get involved! 🌍✨ #InSiGHT

The registries’ combined experiences underscore the critical need for integrated, culturally sensitive strategies combining genetic testing, enhanced surveillance, and family-based management to improve outcomes #Polyposis #LynchSyndrome link.springer.com/article/10.1...

📢 Join us in Singapore for the InSiGHT Biennial Meeting, 4–7 March 2026! 🔹 Abstract Deadline: 20 Sept 2025 🔹 Early Bird: 10 Jan 2026 Link ➡️ insight2026.org Let’s advance hereditary GI cancer research together! #InSiGHT2026 #MedicalResearch #GItumours

Come and work with us! We are seeking a Regional #LynchSyndrome Nursing Lead band 8 for 12 months to provide teaching and training across North London #Genomics apps.trac.jobs/job-advert/7...

Please follow @insight-org.bsky.social on BlueSky and join us for insight2026.org in Singapore, abstract submission now live!

Please follow @insight-org.bsky.social on BlueSky and join us for insight2026.org in Singapore, abstract submission now live!

👋 Welcome to InSiGHT on BlueSky! We are a global community of researchers, clinicians, and scientists dedicated to advancing the understanding, diagnosis, and management of hereditary GI cancers. Follow us for updates on scientific advances, clinical guidelines, and upcoming events. #InSiGHT

Abstract submission is now open for #Insight2026 ! Deadline 7th September #LynchSyndrome #Polyposis #EOCRC @soniakupfer.bsky.social @swatipatelmd.bsky.social @cgaigc.com @stmarksgenomics.bsky.social @plsdatabase.bsky.social insight2026.org

Mainstreaming clinicians in colorectal and Gynae teams… think about this study!

Join us 19-21 November for a bigger and better St Mark's Frontiers in Colorectal Disease Meeting, in a beautiful venue in King's Cross London! Extremely good value, with hybrid options @stmarkshospital.bsky.social sayso.health/events/front...

Join us 19-21 November for a bigger and better St Mark's Frontiers in Colorectal Disease Meeting, in a beautiful venue in King's Cross London! Extremely good value, with hybrid options @stmarkshospital.bsky.social sayso.health/events/front...

Missed opportunities: Germline testing following tumor sequencing pubmed.ncbi.nlm.nih.gov/40554180/

Great to meet up with Pam from Lynch Syndrome UK at BSG Live 2025 in Glasgow today! @thepoodoctor.bsky.social @lynchsyndromeuk.bsky.social @stmarksgenomics.bsky.social

On behalf of InSiGHT, we are delighted to welcome you to the #InSiGHT2026 meeting in Singapore, taking place from 4 – 7 March 2026 #LynchSyndrome #Polyposis @cgaigc.com @stmarksgenomics.bsky.social insight2026.org

On behalf of InSiGHT, we are delighted to welcome you to the #InSiGHT2026 meeting in Singapore, taking place from 4 – 7 March 2026 #LynchSyndrome #Polyposis @cgaigc.com @stmarksgenomics.bsky.social insight2026.org

Lovely new paper from @leedham-simon.bsky.social dissecting epithelium-microenvironment crosstalk through BMP & wnt signalling in the intestine. Inhibition of BMP antagonist GREM1 may forestall polyp formation in Hereditary Mixed Polyposis Syndrome (HMPS). www.nature.com/articles/s41...

In Our Scope of Practice: Genetic Risk Assessment and Testing for GI Cancers and Polyposis in Gastroenterology - @amergastroassn.bsky.social @soniakupfer.bsky.social www.gastrojournal.org/article/S001...

Are you an #endoscopist? Interested in assessing & managing advanced #colonic #polyps? Can we improve our #training in this? @stmarkshospital.bsky.social We are keen to hear your views. Please complete this short survey @esge-news.bsky.social docs.google.com/forms/d/e/1F...

Led by our 2024 president, Bryson Katona, MD, PhD, our Executive Council developed a 3-year strategic plan to guide our society's future We’re proud to share this as we mark our 30th anniversary. Explore the plan 👉https://link.springer.com/article/10.1007/s10689-025-00473-9 #HereditaryGICancer

If you are a from a #colorectalcancer #MDT and offering mainstream #genetic testing to your own patients then please consider joining Detect2 which may half your workload! We’re delighted to have recruited our first 3 patients… get in touch or click below for more www.detect-2.co.uk

Attitudes towards faecal immunochemical testing (FIT) for risk-stratified colonoscopy in people with #Lynchsyndrome #FIT4Lynch @bmj.com bmjopengastro.bmj.com/content/12/1...

The BSL during Finland was sensational #Eurovision

Fantastic meeting about Lynch syndrome and hereditary CRC for MDTs, thanks to @britsocgastro.bsky.social @kevinmonahan.bsky.social and others

Fabulous day today at our @britsocgastro.bsky.social organised #LynchSyndrome event at #RCPLondon sold out, fabulous talks, interactive sessions and audience of clinicians who want to do their best for people with Lynch syndrome #BCSP @nhsmillion.bsky.social @rcphysicians.bsky.social

We are very excited about our @britsocgastro.bsky.social #LynchSyndrome event @rcphysicians.bsky.social next Wednesday… sold out but let me know if you want a place

Primary care: the ‘linchpin’ in Lynch syndrome @bjgp.bsky.social bjgp.org/content/75/7...

Please join our incredible team as an Advanced Nurse Practitioner in Inherited Cancer Syndromes - closing date this Monday 5th May! Provide lifelong care to our very special patient group #LynchSyndrome #FAP #Genomics #polyposis @stmarkshospital.bsky.social lnwh.nhs.uk/jobs/

One hundred years of the St Mark’s hospital polyposis registry @stmarksgenomics.bsky.social @lnwh.bsky.social link.springer.com/article/10.1...

Promising early safety and immunogenicity data from the Nous-209 Lynch Syndrome vaccine presented at AACR this month aacrjournals.org/cancerres/ar...