Freddy Boutrot
@freddyboutrot.bsky.social
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📥 47
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Translational researcher in plant disease resistance @Limagrain, opinions are my own 🌽🌾🧬🔬
reposted by
Freddy Boutrot
Gitta Coaker
5 days ago
Enhancing NLR activation by endophytes carrying recognized effectors that are expressed in the presence of ROS.
#plantimmunity
www.cell.com/cell-host-mi...
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Genetically engineered plant endophytes broaden effector-triggered immunity
Hou et al. engineer plant endophytes to express effectors that trigger NLR-mediated ETI upon pathogen infection, regardless of whether pathogens carry recognizable effectors. The sentinel bacterium ma...
https://www.cell.com/cell-host-microbe/abstract/S1931-3128(25)00392-0?dgcid=raven_jbs_etoc_email
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Freddy Boutrot
Nature Plants
7 days ago
Our editors write: - "Plant immunity: Engineering RLP receptors from the C side"
rdcu.be/ePaS1
A brief highlight of this Article in
@natbiotech.nature.com
: "Engineered pattern recognition receptors enhance broad-spectrum plant resistance" about swapping C-term domains
rdcu.be/ePaTW
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Freddy Boutrot
14 days ago
We wrote a review 📖 on hydathode immunity! Learn how bacteria exploit hydathodes to access the vasculature and open questions for future research. 📣 If you are curious about this topic, please consider applying for two open positions in my lab (until Nov23)!
www.sciencedirect.com/science/arti...
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Hydathodes at the forefront of plant immunity against vascular pathogens
Hydathodes are tiny plant organs that form an interface between the leaf surface and xylem vasculature. They facilitate excretion of xylem fluid under…
https://www.sciencedirect.com/science/article/pii/S1369526625001360
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Freddy Boutrot
Sebastian Schornack
11 days ago
Plz RP. Come join us at
@slcuplants.bsky.social
@cam.ac.uk
to study effector-targeted plant processes impacting plant cell biology and development.
www.cam.ac.uk/jobs/post-do...
www.schornacklab.net
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Adam Mott
11 days ago
Cool new paper on receptor specificity.
www.nature.com/articles/s41...
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Two residues reprogram immunity receptors for nitrogen-fixing symbiosis - Nature
An investigation of plant receptor-like kinases identifies regions of these proteins that control whether immune or symbiotic signalling pathways are activated, with minimal changes to specific r...
https://www.nature.com/articles/s41586-025-09696-3
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Freddy Boutrot
Mariana Schuster
14 days ago
Thrilled to share our latest review on receptor kinase processing in plants! 🌱 Huge congratulations to
@adithya1972.bsky.social
and Anna for leading this work, and a big thank you to our fantastic collaborator Martina-Ried Lasi for making this a truly rewarding team effort!
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Shedding light on receptor kinase processing
https://journals.plos.org/plospathogens/article?id=10.1371/journal.ppat.1013648&?utm_id=plos111&utm_source=internal&utm_medium=email&utm_campaign=author
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Freddy Boutrot
Isabel saur
16 days ago
Postdoc position in my lab in Cologne starting early next year or latest in spring to get this exciting project started.
jobportal.uni-koeln.de/ausschreibun...
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https://jobportal.uni-koeln.de/ausschreibung/renderFile/2380?propertyName=flyer
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Freddy Boutrot
Ksenia Krasileva
19 days ago
🚀 New preprint! We introduce K-PROB, a k-mer–based Bayesian framework that mines pangenomic promoter and expression diversity to predict cis-regulatory elements driving gene expression variation in crops 🌽🌱 🔗
biorxiv.org/content/10.1101/2025.10.27.684862v1
#Genomics
#GeneRegulation
#Maize
#Soybean
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Natural variation in regulatory code revealed through Bayesian analysis of plant pan-genomes and pan-transcriptomes
Understanding the genetic code of cis-regulatory elements (CREs) is essential for engineering gene expression and modulating agronomic traits in crops. In plants, CREs underlying rapid evolution of ge...
https://biorxiv.org/content/10.1101/2025.10.27.684862v1
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Freddy Boutrot
Ksenia Krasileva
19 days ago
The work is led by
@weiweibio.bsky.social
, a talented postdoc looking for faculty positions now and conceptualized both computational prediction and in lab validation. Computational implementation is a collaboration with Xing Wu, postdoc with
@mexpositoalonso.bsky.social
Qs - contact us 💻🌱🧬
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Freddy Boutrot
Danve Castroverde
21 days ago
N-hydroxy-pipecolic acid-mediated signal transduction and resistance requires DAWDLE url:
academic.oup.com/plphys/artic...
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N-hydroxy-pipecolic acid-mediated signal transduction and resistance requires DAWDLE
The Arabidopsis gene DAWDLE activates systemic acquired resistance by regulating immune-related genes induced by N-hydroxy-pipecolic acid.
https://academic.oup.com/plphys/article/doi/10.1093/plphys/kiaf536/8300520
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Freddy Boutrot
David Thoms, PhD
25 days ago
Excited that our paper was just published! It's a revised version with new insights compared to the preprint. Thanks everyone from the
@carahaney.bsky.social
Lab!
www.cell.com/cell-reports...
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A bacterial exotoxin-triggered plant immune response restricts pathogen growth
Thoms et al. demonstrate that perception of a bacterial exotoxin allows plants to distinguish between closely related microbiota, which has consequences for rhizosphere microbiome structure and functi...
https://www.cell.com/cell-reports/fulltext/S2211-1247(25)01228-8
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Freddy Boutrot
Ken Shirasu
25 days ago
Simon's mutant finally published! Well done, Satoko' lab with Harro, Tobimatsu, Tohge collaborations. Glucosylation of endogenous haustorium-inducing factors underpins kin avoidance in parasitic plants | Science
www.science.org/doi/10.1126/...
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Glucosylation of endogenous haustorium-inducing factors underpins kin avoidance in parasitic plants
Parasitic plants rarely attack themselves, suggesting the existence of a kin-avoidance mechanism. In the root parasitic plant Phtheirospermum japonicum, prehaustorium formation is triggered by host-se...
https://www.science.org/doi/10.1126/science.adx8220
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Freddy Boutrot
Pingtao Ding (he/him)
25 days ago
Humbly share our latest work led by
@himanshuchhillar.bsky.social
my phd student And thanks to all collaborators Henk-jan
@brunongou.bsky.social
@jonathandgjones.bsky.social
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Freddy Boutrot
Bryony Jacobs
28 days ago
Some of my favourite research from my PhD was submitted today... I feel very lucky to have worked on this project with such wonderful scientists (and lovely people!) Please check it out on bioRxiv here👇🌱🦠
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Freddy Boutrot
Team Thomma
about 1 month ago
📣 New
@biorxiv-microbiol.bsky.social
preprint, another joint-venture of
@wolki95.bsky.social
&
@antonkraege.bsky.social
, co-directed by
@nicksnelders.bsky.social
. Here’s a 🧵
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Freddy Boutrot
Christine Faulkner
about 1 month ago
New pre-print from the team! The manuscript is
@emma-raven.bsky.social
's PhD work showing that whether a leaf is a carbon sink or a carbon source influences how they execute immune responses. Have a read!
#PlantScience
@johninnescentre.bsky.social
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Uncovering Convergent Pattern Recognition Receptors Recognising Phytophthora Across Plant Lineages
doi.org/10.1111/pbi....
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Uncovering Convergent Pattern Recognition Receptors Recognising Phytophthora Across Plant Lineages
Pattern recognition receptors (PRRs) are pivotal for plant immunity, yet their discovery in crops is hindered by lineage-specific divergence. We demonstrate that microbe-associated molecular patterns....
https://doi.org/10.1111/pbi.70409
about 1 month ago
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Freddy Boutrot
Molecular Plant & Plant Communications
about 1 month ago
Recognition of a phytocytokine by the DEPR1-SERK2 receptor complex confers multi-pathogen resistance in wheat
#research
#MolecularPlant
cell.com/molecular-pl...
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Freddy Boutrot
Eva Stukenbrock
about 1 month ago
Professorship in plant genetics. The Botanical Institute at Kiel University is advertising a W2 professorship. Great opportunity to do plant research in the north of Germany. See:
www.berufungen.uni-kiel.de/de/dateien/o...
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https://www.berufungen.uni-kiel.de/de/dateien/oeffentl.-dateien/w2/pflanzengenetik/
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Freddy Boutrot
Isabel Monte
about 1 month ago
Fran
@frangordilloc.bsky.social
and I wrote this piece on one of our favorite topics: the evolutionary relevance of co-receptors for immune receptor transfer in
#plants
🌱
#EvoMPMI
#MPMI
Check also the beautiful paper by Zhang et al. on the PRR STOMR and discover what happened to its co-receptor 😱
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Freddy Boutrot
Marc Somssich
about 1 month ago
Nataliia Rybchenko from
@kwsgroup.bsky.social
Ukraine presented her 'Sunflower' documentary at the
#KWSScienceSlam
. Ukraine is the global leader in sunflower oil production, but amid the war, the sunflower has also become a symbol of freedom for Ukraine. Documentary:
www.youtube.com/watch?v=2u2U...
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Freddy Boutrot
Thomas WIDIEZ
about 1 month ago
🌽 Maize vs. Fusarium 🌽 Overexpressing a maize lipoxygenase (ZmLOX4) boosts resistance to Fusarium infection. Glad that our maize Gene editing & transformation platform, at
@rdplab.bsky.social
, contributed to this research, led by the Lanubile's Lab. ▶️
doi.org/10.1093/jxb/...
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Freddy Boutrot
bioRxiv Plant Bio
about 1 month ago
A secreted citrus protease cleaves an outer membrane protein of the Huanglongbing pathogen
https://www.biorxiv.org/content/10.1101/2025.10.06.680679v1
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Freddy Boutrot
Journal of Experimental Botany
about 1 month ago
💡 SPECIAL ISSUE VIEWPOINT 💡 Immune proteases are promising targets for protein engineering 🛠️ to boost disease resistance in plants 🌾 - Schuster et al. 🔗
doi.org/10.1093/jxb/...
#PlantScience
🧪
@marischuster.bsky.social
@aciattoni.bsky.social
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Freddy Boutrot
Danve Castroverde
about 2 months ago
Engineered geminivirus replicons enable rapid in planta directed evolution
www.science.org/doi/10.1126/...
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Engineered geminivirus replicons enable rapid in planta directed evolution
Directed evolution can rapidly generate genetic variants with new and enhanced properties, yet efficient platforms for performing such evolution directly in plant cells have been lacking. We developed...
https://www.science.org/doi/10.1126/science.ady2167
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Freddy Boutrot
ZMBP
about 2 months ago
Have you noticed someone new here? 👇 Welcome
@mpcontreras.bsky.social
, our new junior group leader at the ZMBP!
#newPI
#plantscience
#MPMI
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Freddy Boutrot
Gabriel Mendoza-Rojas
about 2 months ago
🧵How does a pathogen know it has entered its host? New preprint!🎉It’s a pleasure to share my first first-author preprint from my PhD journey! We uncover a novel co-evolved peptide–GPCR system in the fungus Ustilago maydis that senses host entry and triggers infection (
doi.org/10.1101/2025...
) (1/5)
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Freddy Boutrot
Michael Hothorn
about 2 months ago
Amazing work by the Santiago lab
@unil.bsky.social
. The malectin-LRR receptor kinase IGP1 senses cello-oligomers to alert the plant immune system & enhance disease resistance. Very nice discovery & mechanism.
www.biorxiv.org/content/10.1...
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A RALF-brassinosteroid signaling circuit regulates Arabidopsis hypocotyl cell shape
doi.org/10.1016/j.cu...
about 2 months ago
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Freddy Boutrot
Helen Brabham
about 2 months ago
Super excited to see our work on the NLRseek program finally published 🥳 Here we identify new NLRs against major wheat pathogens and present a pipeline for NLR identification. Huge thank you to all of the co-authors for bringing this work together!
@matthewmoscou.bsky.social
rdcu.be/eIGvv
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Discovery of functional NLRs using expression level, high-throughput transformation and large-scale phenotyping
Nature Plants - Rapid discovery of functional resistance genes is enabled by a high-expression signature and high-throughput transformation. This approach identified 31 new resistance genes for...
https://rdcu.be/eIGvv
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Freddy Boutrot
International Society for Molecular Plant-Microbe Interactions
about 2 months ago
Couldn’t make it to Cologne? No problem—IS-MPMI Rewind is here! Get access: https://bit.ly/4mDryZg Members: $49 | Nonmembers: $79 Congress attendees can access Rewind as part of their registration.
#2025ISMPMI
#ISMPMIrewind
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Freddy Boutrot
GeminiTeamLab
2 months ago
📢 A Junior Professorship (W1, tenure track) is open at the Center for Plant Molecular Biology at Uni Tübingen (
@zmbp-tuebingen.bsky.social
) — to work on plant protein biochemistry (composition, structure, dynamics, or regulation of protein complexes). 🌱 Great opportunity — Apply by Oct 17th!
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Freddy Boutrot
Isabelle Fudal
about 2 months ago
Now published in Plant Pathology. 'Molecular Investigation of Rlm3 From Rapeseed as a Potential Broad‐Spectrum Resistance Gene Against Fungal Pathogens Producing Structurally Conserved Effectors' - Talbi - Plant Pathology - Wiley Online Library
bsppjournals.onlinelibrary.wiley.com/doi/10.1111/...
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CEPR2 perceives group II CEPs to regulate cell surface receptor-mediated immunity in Arabidopsis
doi.org/10.1371/jour...
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CEPR2 perceives group II CEPs to regulate cell surface receptor-mediated immunity in Arabidopsis
Author summary To protect themselves against pathogens, plants have evolved a sophisticated and intricate immune system that allows pathogen detection and the activation of appropriate defense respons...
https://doi.org/10.1371/journal.ppat.1013115
about 2 months ago
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Freddy Boutrot
Volker Lipka
about 2 months ago
We proudly present a new preprint by Leon Pierdzig et al: Wall teichoic acids, glycopolymers specific to Gram-positive bacteria, trigger defense and cell death in Arabidopsis. Cysteine-rich RLKs act as key components in their perception.
doi.org/10.1101/2025...
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Freddy Boutrot
bioRxiv Plant Bio
about 2 months ago
Cysteine-rich receptor-like kinases mediate Wall Teichoic Acid perception in Arabidopsis
https://www.biorxiv.org/content/10.1101/2025.09.18.677107v1
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Freddy Boutrot
Ken Shirasu
2 months ago
Well done, Max! Neofunctionalized RGF pathways drive haustorial organogenesis in parasitic plants | Science Advances
www.science.org/doi/10.1126/...
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Neofunctionalized RGF pathways drive haustorial organogenesis in parasitic plants
Plant peptide hormones regulate and induce the parasitic plant specialized organ for connecting to and feeding from the host.
https://www.science.org/doi/10.1126/sciadv.adw3965
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Freddy Boutrot
Ksenia Krasileva
2 months ago
New: ‘Kronos’
#wheat
genome preprint • PacBio+Hi-C; 99.9% BUSCO • 2.3k curated NLR loci (1,089 high conf) • 3k EMS datasets re-mapped; 📈 new mutations • Curated smallRNA atlas 🔗
www.biorxiv.org/content/10.1...
zenodo.org/records/1021...
#genomics
#openscience
team effort led by Dr Kyungyong Seong 💫
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The Annotated Blueprint: Integrated Functional Genomic Resources for a Model Tetraploid Wheat Triticum turgidum cv. Kronos
Triticum turgidum cv. Kronos is a tetraploid wheat cultivar that underpins one of the richest community platforms for functional genomics. Over the past decade, about 3,000 exome- and promoter-capture...
https://www.biorxiv.org/content/10.1101/2025.09.12.675711v1
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Freddy Boutrot
Mariana Schuster
2 months ago
Just 🤯
www.nature.com/articles/s41...
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Charting γ-secretase substrates by explainable AI - Nature Communications
Comparative Physicochemical Profiling (CPP), an interpretable machine learning algorithm, identifies physicochemical signatures of γ-secretase substrates, capturing features hidden in sequences and en...
https://www.nature.com/articles/s41467-025-60638-z
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Freddy Boutrot
2 months ago
Call for a tenure-track position at our Department of Plant Molecular Biology in Lausanne! We are searching for promising early-career researchers in the broad field of plant-organismal interactions. Deadline: November 30, 2025 - Please re-post!
career5.successfactors.eu/career?caree...
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Career Opportunities: DBMV: Tenure Track Assistant Professor towards Associate Professor in the field of Plant-organism (22484)
https://career5.successfactors.eu/career?career%5fns=job%5flisting&company=universitdP&navBarLevel=JOB%5fSEARCH&rcm%5fsite%5flocale=en%5fUS&career_job_req_id=22484&selected_lang=en_US&jobAlertController_jobAlertId=&jobAlertController_jobAlertName=&browserTimeZone=Europe/Zurich&_s.crb=kX%2flqloffOMPUSNmJBKig4RwtuZbfADI8MRbx13TBC8%3d
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Freddy Boutrot
Gitta Coaker
2 months ago
Happy to share this review on the diversity of resistance in Triticeae. I learned a lot writing it. Heavy lifting by Yinghui Li, Liubov Govta, and
@yichangsung.bsky.social
with our long-time collaborator Tzion Fahima.
www.annualreviews.org/content/jour...
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The Spectrum of Diverse Disease-Resistance Genes Cloned and Characterized in the Triticeae Tribe | Annual Reviews
The Triticeae tribe comprises species representing some of the world's largest food and forage crops, including common wheat, durum, barley, rye, and oat. Crop yields are continuously threatened ...
https://www.annualreviews.org/content/journals/10.1146/annurev-phyto-121323-031121
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Freddy Boutrot
Christina Steidele
2 months ago
Happy to share our pre-print!
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An apoplastic fungal effector disrupts N-glycosylation of ZmLecRK1, inducing its degradation to suppress disease resistance in maize
doi.org/10.1038/s414...
2 months ago
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Freddy Boutrot
Edel Pérez-López 🇨🇦
2 months ago
Resistance gene enrichment sequencing refines the Brassica napus NLRome url:
academic.oup.com/plphys/artic...
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Resistance gene enrichment sequencing refines the Brassica napus NLRome
Resistance gene enrichment sequencing produces a complete repertoire of nucleotide-binding leucine-rich repeat receptors for Brassica napus, overcoming pri
https://academic.oup.com/plphys/article/197/3/kiae631/7911763
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Freddy Boutrot
Dan Sloan
2 months ago
The Department of Biology at Colorado State University is hiring an Assistant Professor in the area of plant-microbe interactions! Please spread the word!
jobs.colostate.edu/postings/165...
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Assistant Professor Plant-Microbe Interactions
We seek a creative, collaborative, and visionary plant biologist to establish an internationally recognized research program at the forefront of plant-microbe interactions aimed at understanding how t...
https://jobs.colostate.edu/postings/165524
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Freddy Boutrot
FMI science
2 months ago
🚨 We're hiring, please share! The FMI seeks a tenure-track Group Leader (Assistant Prof) in Structural Biology 🔬 Innovative scientists in genome regulation, RNA metabolism, or protein homeostasis—especially using cutting-edge approaches—apply now at
www.fmi.ch/education-ca...
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Freddy Boutrot
Bruno Ngou
2 months ago
Very happy to share our latest work “Systematic discovery and engineering of synthetic immune receptors in plants” out in
@science.org
!
www.science.org/doi/10.1126/...
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Systematic discovery and engineering of synthetic immune receptors in plants
Plants deploy a diverse array of pattern recognition receptors (PRRs), which perceive microbe-associated molecular patterns to activate immune responses. Leucine-rich repeat receptor-like kinase subgr...
https://www.science.org/doi/10.1126/science.adx2508
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Freddy Boutrot
Adam Steinbrenner
2 months ago
More fruits of studying natural variation in common bean (Phaseolus vulgaris): an interesting genetic basis for insensitivity to caterpillars' In11 elicitor 🐛 Our new bioRxiv preprint from star technicians Brian Behnken and Wesley George below 🧵
www.biorxiv.org/content/10.1...
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Freddy Boutrot
Pingtao Ding (he/him)
2 months ago
Congratulations
@brunongou.bsky.social
@shirasulab.bsky.social
and colleagues
www.science.org/doi/10.1126/...
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Systematic discovery and engineering of synthetic immune receptors in plants
Plants deploy a diverse array of pattern recognition receptors (PRRs), which perceive microbe-associated molecular patterns to activate immune responses. Leucine-rich repeat receptor-like kinase subgr...
https://www.science.org/doi/10.1126/science.adx2508
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Freddy Boutrot
KWS Group
2 months ago
EFSA just released their first scan of new scientific data on
#NGTs
, confirming that no new hazards or risks were identified beyond those previously considered. Fulll report accessible via the link 👇
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