www.biorxiv.org/content/10.1... Our latest: Julien Pigeon and colleagues discover a mechanism linking post-translational modification of transcription factors to remodeling the chromatin landscape to regulate human cortical neurogenesis

I am very happy (and a bit scared) to present to you what we have been working on over the last 4 years. This manuscript is exactly what I dreamt of when I started the lab and I could not be happier and prouder of the outcome!

Today, I pay tribute to Dr. Jane Goudall — remarkable scientist, who was truly inspirational. Her groundbreaking work, commitment not only transformed our understanding of the natural world but also inspired generations, including myself, to pursue science with purpose and passion. janegoodall.org

🧵1/14 Preprint thread! Can we predict a cell’s fate based on its dynamics? 🔮 Our new study unveils a framework for watching development unfold in real-time, revealing how a cell's shape and movement encode info about its future fate. 🔬📄 Preprint: tinyurl.com/4shf8v4x

Latest from the lab: the immensely talented Johnny Bou Rouphael and Laila El Khattabi in the team report the discovery and functional analysis defective splicing in a human developmental disorder. www.linkedin.com/posts/bassem...

Ever wondered how robust cellular identity is to external perturbations? Here we disrupt cellular environmnent in vivo and in vitro, and find cell population specific sensitivities. Environment sculpts development yes, but not all cells are made of the same wood. www.science.org/doi/10.1126/...

Registration is now open for 2026 GRC on Neural Development @neuraldevgrc.bsky.social Register early because places go fast!

Latest from the lab, the beautiful work of Iryna Mohylyak and colleagues describing a temporal developmental transcriptional program for mitochondrial quality control and synaptic connectivity, with @jdejuan-sanz.bsky.social, Olga Corti and @steinaerts.bsky.social labs www.nature.com/articles/s41...

Dear [email protected], dear [email protected], to learn more about the importance of #Drosophila and crucial role of @flybase.bsky.social, and how it gave rise to at least 9 Nobel laureates in Physiology and Medicine, please see this link: droso4schools.wordpress.com/why-fly/

It is a Great Honour to receive the 'Les Grandes Avancées en Biologie' award 🏅 from the @academiesciences.bsky.social and to share our work during this fabulous day celebrating Science. Thank you! @hassanbraindevlab.bsky.social @institutducerveau.bsky.social @frm-officiel.bsky.social

European-based researchers can help support future #flybase curation by donating at this site: www.philanthropy.cam.ac.uk/give-to-camb...

FlyBase needs our help.

New from the lab: @maheandria.bsky.social and colleagues in collaboration with the Hiesinger, Stoeckli and von Kleist labs dissect the sequential emergence of axonal targeting during development in today's issue of Nature Neuroscience: rdcu.be/ek010

Hot off the press: The excellent Maheva Andriatsilavo and colleagues show how a temporal sequence of stochastic molecular mechanisms allow the emergence of stereotyped individualised neuronal circuits. Just published in Nature Neuroscience: rdcu.be/ek010

Highly recommended !

Proud to share my main postdoc work! 🧠 I asked: How to build a #brain that lead to #individuality? We show that adult brain wiring isn't fully predictable from genes or environment alone— the #stochastic nature of #development is a key third factor. #NatureNeuroscience www.nature.com/articles/s41...

“Decoding the brain: from methods to meaning." A great workshop to brainstorm! 👇

How to define a (neural) cell type? Happy to share this piece of thought we put together with ‪@bassemh.bsky.social.

Hi Fly, Mouse, Rat, Zebrafish, Worm, and Yeast communities- Looking for the latest numbers on gene conservation between your favorite species and humans (like I was!)? Please see this excellent review (Table 2) by S Yamamoto, @okanca.bsky.social, M Wrangler, and H Bellen rdcu.be/efiXa

Do not miss any news from the Pint of Science Festival! Pour ne rien rater du festival Pint of Science 🗓️ 19-21.05 👉 @pintsWorld.bsky.social

Journée portes ouvertes : le saviez-vous ? Les mouches drosophiles sont des modèles de choix pour les scientifiques. En effet, leur cerveau fonctionne selon les mêmes principes physiologiques que le cerveau humain.

📣 Postdoc opportunity ! Our lab is hiring a funded postdoc to explore the development of fear circuits using slice electrophysiology. If you have expertise in this area and are interested about cutting-edge neuroscience, reach out ! 🤗 klinglerlab.org Please share with your network 🙏

Today, Paris Brain Institute is joining forces with the #StandUpForScience movement to defend science and the scientists who make it.

🎉 Our @dianapinheiro.bsky.social is featured in a Women in Science book! The book, part of @cienciaviva.bsky.social's initiative, celebrates Portuguese women scientists. The latest volume launches tomorrow, #InternationalWomensDay, in Lisbon. 📖 Read more: imp.ac.at/news/article... #IWD2025

“An assault on science and scientists anywhere is an assault on science and scientists everywhere.” That says it all.

France, now is not the time to reduce our scientific attractiveness !

At the NIH, posters of women and scientists of color have been taken down. Shared by @ivancalcantara.bsky.social on X. 2/x

Wonderful talk from Robin Hiesinger on how natural neuronal networks self-organise: The Neurobiology of Artificial Intelligence youtu.be/OWnsVWKJCEs?...

🚨 Postdoc wanted 🚨 Ever wondered how mechanical forces shape the heart tube during embryogenesis?… I am looking for a postdoc with a background in developmental biology or biophysics to investigate this new topic as part of an ANR-JCJC 🚀🔬 Don’t hesitate to contact me 🤓🔗

How cells decide where to go? #CellMigration Last year we published our 1st paper @cellcommlab.bsky.social, showing how actin-based membrane oscillations define a new direction ( #cancer & non-cancer #cells ) Full www.nature.com/articles/s41... @naturephysics.bsky.social @focalplane.bsky.social 🧪🔬

It’s official 🎉 I am excited to share that I will start my lab this spring at the Max Planck Institute for Immunobiology and Epigenetics @mpi-ie.bsky.social in beautiful Freiburg 🤩🗻☀️ I am looking forward to new collaborations and working with the fantastic community in Freiburg & its surroundings!

A reminder: for genotypes to produce phenotypes, they have to go through development

Here are some important populations of columnar neurons in the #Drosophila right optic lobe, from the #connectome released in April 2024 again. Note the subtle variations in morphologies. I made this video with Michael Reiser ( @michaelreiser.bsky.social), using neuVid driving #Blender.

The real IFT… intra💥filopodial💥transport. @vucellimaging.bsky.social #cytoskeleton #biology #microscopy

What a beautiful day to start posting on 🦋 Happy Drosophila day 🪰