🚀New pre-print from the lab, led by PhD candidate Xiaolin Dong! www.biorxiv.org/content/10.6... In this study, we uncovered crosstalk between mucin-type O-glycans and HSPGs, showing that truncated O-GalNAc glycans destabilize proteoglycans, impair FGF signaling, & disrupt chondrogenesis. #glycotime

🚀 BIH is recruiting for its PhD Program! Work on cutting-edge translational projects spanning immunotherapy, genomics, AI, hematopoiesis, precision medicine & more. Apply by Jan 19, 2026. 🔗 Join us in turning research into health! www.bihealth.org/en/career/wo...

Fascinating study (and thread) about the role of cytoplasmic MLH1 in residual tumor cells that go on to seed ER+ breast cancer recurrences

Check our new venture into drug discovery #glycotime!

Comprehensive experiments in pre-clinical models and clinical data analysis demonstrate that dormancy creates a unique window of opportunity to deplete minimal residual disease and delay recurrence. Congratulations to all the authors on this important body of work!

New paper online: Ångström-resolution imaging of cell-surface glycans. The molecular organization of sugars in the native #glycocalyx has been resolved at 9 ångström using bioorthogonal metabolic labeling and #superresolution imaging of DNA barcodes. #Glycotime www.nature.com/articles/s41...

World central kitchen has been doing great work consistently. Every meal counts. Donate here. donate.wck.org/give/525879/...

As a budding scientist, the idea that form follows function led me to a career studying developmental biology and how these principles are distorted in cancer. Excited to share this preprint reporting a surprising transdifferentiation of breast cancer cells unlocked by dormancy. Link below:

Kudos to the @theaacr.bsky.social for making it easy to reach out to your representatives. Nice to see courage and action. nam02.safelinks.protection.outlook.com?url=https%3A...

Check it out, powerful new method for optical imaging of the live ECM, from @hhmijanelia.bsky.social Group Leader Kayvon Pedram #proudofalumni #glycotime www.nature.com/articles/s41...

Apply for our Pathway to Independence programme, a scheme supporting postdocs going on the job market in 2025 with training, mentorship, profile-raising and networking opportunities. Apply by 31 Jan 2025: https://buff.ly/3VJGgDC

#aECM (apical extracellular matrix) is a subset of #ECMatrix that is distinct from stromal matrices or basement membranes. Anybody out there studying #mucins #ZPproteins #cuticle #glycocalyx #surfactant or the like? We need to find each other and start talking!

The secret is out! 🚀 Thrilled to support Valora's mission to bring our #AbLec technology to patients, alongside co-inventor @carolynbertozzi.bsky.social. More to come, and in the meantime, you can learn more about AbLecs here: www.biorxiv.org/content/10.1...

Pls share 🌟Join the IMP as a Group Leader We are 👀 for a colleague, ready to lead a groundbreaking research program. Enjoy generous funding, outstanding facilities & a vibrant scientific community in one of the world's most livable cities @impvienna.bsky.social 👉https://tinyurl.com/impgl2025

Ever wondered how gene therapies know where to go? Screening AAV vector libraries across different species I uncovered evidence of altered #glycan profiles between mouse, NHP and human liver, with implications for translation of #AAV #genetherapy pubmed.ncbi.nlm.nih.gov/39001819/ Enjoy!

Thank you to the organizers of #SFG2024 for hosting a wonderful meeting @sfglycobiology.bsky.social As a 1st time attendee, it was a privilege to present my work on B3galt6-heparan sulfate biosynthesis as a functional regulator of dormant breast cancer cell survival. www.cell.com/cancer-cell/...

#SFG24 was so much fun - amazing #glycotime in a fantastic place. The right mix between talks by legends in the field and early career colleagues. Thank you to the organizers! I contributed our own story on xylosyltransferase bump-and-hole engineering, check here: www.biorxiv.org/content/10.1...

For those of you that prefer feeds over following, I've figured out how to convert starter packs into lists, so you can get your glyco fix as a feed. If you're on the starter pack, you're on the list, and anyone new on the starter pack will get added to the feed!

It seems to me that the time is ripe for a Bluesky thread about how—and maybe even why—to befriend crows. (1/n)

As someone who has gained a lot of knowledge and career advice from fellow glycobiologists, I wanted to recreate a space for discussion on Bluesky. Here's a starter pack with some glycobiology users to get started. Please comment/DM me to get added to the #glycotime starter pack go.bsky.app/CN9pS3u

Happy to announce that, on the eve of this year's Society for Glycobiology meeting, my second paper from my collaboration with the great Nancy Dahms is out! Really proud of this one. Biggest protein we've ever footprinted, a real challenge! #glycotime 🧪