Theo Sanderson
@theo.io
📤 17066
📥 706
📝 760
researching viral pathogen genomics at
@lshtm.bsky.social
| theo.io / sandersonlab.org
reposted by
Theo Sanderson
Ryan Moulton
2 days ago
Wat
add a skeleton here at some point
5
148
49
reposted by
Theo Sanderson
Sarah O'Connor
1 day ago
Such a good piece today from
@jburnmurdoch.ft.com
which shows that the declining graduate premium is very much a UK problem rather than a general (or inevevitable) consequence of more people going to uni
www.ft.com/content/649d...
9
190
83
somewhat terrifying
chatjimmy.ai
add a skeleton here at some point
2 days ago
0
12
3
reposted by
Theo Sanderson
Ryan Moulton
3 days ago
Hypothesis: AI writing is bad primarily because in general what makes writing good is the specificity of what it communicates and its information density, so the prompt that produced good AI writing would be as long as the output.
26
165
23
This is a rare case where if you give a screenshot of this post to ChatGPT/Claude and ask it to explain the joke, if any, it doesn't get it
add a skeleton here at some point
3 days ago
2
25
0
sick claude is rather tragic
4 days ago
1
8
1
reposted by
Theo Sanderson
Alex Hern
4 days ago
Oh this is what it feels like to be a reactionary
add a skeleton here at some point
3
37
11
reposted by
Theo Sanderson
spacecowboy
6 days ago
Here is a very rough version of the For You Stats dashboard:
linklonk.com/foryou
It shows you 3 things: - how much you've been using For You - how many views and likes your posts got in For You - how your likes/reposts helped surface posts to other people in For You Feedback welcome
18
342
93
seems bad
add a skeleton here at some point
8 days ago
0
7
1
reposted by
Theo Sanderson
Grace
9 days ago
Ok, clicking through to the blog post that this blog post is referencing, the author makes this point directly:
theshamblog.com/an-ai-agent-...
add a skeleton here at some point
7
65
7
reposted by
Theo Sanderson
Simon Willison
9 days ago
Genuinely very impressed by the SVG of a pelican riding a bicycle I just got out of Google's new Gemini 3 Deep Think model
simonwillison.net/2026/Feb/12/...
loading . . .
Gemini 3 Deep Think
New from Google. They say it's "built to push the frontier of intelligence and solve modern challenges across science, research, and engineering". It drew me a really good SVG of …
https://simonwillison.net/2026/Feb/12/gemini-3-deep-think/
19
257
24
Gemini Deep Think Oneshot! Note the Oxpecker bird on the hippo!
gist.github.com/theosanderso...
add a skeleton here at some point
9 days ago
6
71
5
reposted by
Theo Sanderson
Rohit
9 days ago
See paper in Nature, looks interesting, read it, the latest model they evaluated was o1 preview. This needs to stop. I understand publishing timelines are long but at least change your headline or the abstract.
0
21
6
reposted by
Theo Sanderson
ARTIC Network
10 days ago
ARTIC 2 measles resources are live! As part of the Wellcome Trust funded ARTIC 2 project we have developed a collection of measles virus resources that are now openly available at
artic.network/viruses/mev
1
17
12
what a time to be alive
add a skeleton here at some point
9 days ago
4
35
11
reposted by
Theo Sanderson
Martin Robbins
11 days ago
My latest, on a town's escalating fight to fix a broken road, in which become accidentally radicalised by Nick Offerman.
m.youtube.com/watch?v=RKiV...
loading . . .
'Potholesville' - the road that can't be fixed
YouTube video by The Value of Nothing
https://m.youtube.com/watch?v=RKiV4lC6WzQ
5
32
20
So many low hanging fruit now due to agentic development, but hard to decide whether they are worth picking when anyone can do so
10 days ago
1
11
2
New Claude bug spotted (reproducible), any theories?
10 days ago
9
58
6
ahaha, I'm regenerating the map labels to reflect the fact that they are landmarks on a landscape rather than classifications of individuals, but I might need to do another pass (Sonnet may be less diplomatic than Haiku)
11 days ago
15
188
21
reposted by
Theo Sanderson
Zamin Iqbal
12 days ago
A long time ago in a galaxy far away, there was a SARS-CoV-2 pandemic. Our paper, led by
@martibartfast.bsky.social
a) correcting errors in 4.5 million genomes & their phylogeny b) improving representation of the Global South in public data
www.nature.com/articles/s41...
(thread 1/n)
loading . . .
Addressing pandemic-wide systematic errors in the SARS-CoV-2 phylogeny - Nature Methods
This Resource paper presents a global SARS-CoV-2 phylogenetic tree of 4,471,579 high-quality genomes consistently constructed by Viridian, an efficient amplicon-aware assembler.
https://www.nature.com/articles/s41592-025-02947-1
3
130
69
I made a map of 3.4 million Bluesky users - see if you can find yourself!
bluesky-map.theo.io
I've seen some similar projects, but IMO this seems to better capture some of the fine-grained detail
loading . . .
Bluesky Map
Interactive map of 3.4 million Bluesky users, visualised by their follower pattern.
http://bluesky-map.theo.io/
13 days ago
656
7153
6735
TIL of this page to tell you which posts you liked to cause For You (
bsky.app/profile/spac...
) to recommend a particular post:
linklonk.com/bluesky
add a skeleton here at some point
14 days ago
0
9
3
I've peaked (thanks to a rainy day and a nicher course)
15 days ago
0
11
0
opus 4.6 is a significant step up at my openscad benchmarks
16 days ago
6
96
8
reposted by
Theo Sanderson
John David Pressman
19 days ago
This is the actual author of this video btw
add a skeleton here at some point
1
40
2
reposted by
Theo Sanderson
norvid_studies
20 days ago
--dangerously-skip-understanding
0
117
17
reposted by
Theo Sanderson
Kirsty Grainger
23 days ago
OOOOH Researchfish Is going extinct 🐡🐟🐠
help.researchfish.com/en_US/resear...
loading . . .
Researchfish — Information for Researchers Regarding Researchfish Sunsetting
After careful consideration, Elsevier have made the difficult decision to sunset Researchfish on July 31st 2027, when the product will no longer be availab
https://help.researchfish.com/en_US/researchers/information-for-researchers-regarding-researchfish-sunsetting
14
83
82
Finally got around to digging out my old desktop getting it set up with tailscale and dangerclaude. Has definitely been worth the faff to be able to leave claude to do its thing in a relatively safe environment (just w/ screen/tmux mostly)
23 days ago
0
2
2
reposted by
Theo Sanderson
Singularity's Bounty e/🇺🇦
28 days ago
wild that the future has arrived and it uses ANSI text graphics
1
21
3
Made a quick thing to generate these test prompts:
theosanderson.github.io/wordblanker/
dang impressive ime
add a skeleton here at some point
about 1 month ago
1
4
0
reposted by
Theo Sanderson
Tom Peacock
about 1 month ago
Really excited our paper about how H5N1 rapidly adapted to cattle (and how these adaptations also increased its ability to infect cells from the human respiratory tract) is now published!
www.nature.com/articles/s41...
loading . . .
Polymerase mutations underlie early adaptation of H5N1 influenza virus to dairy cattle and other mammals - Nature Communications
Avian influenza jumped from wild birds into dairy cattle. Here, the authors report that two mutations in the viral polymerase helped the virus to quickly adapt to cattle. Mutations increased the polym...
https://www.nature.com/articles/s41467-026-68306-6
1
85
47
need an aurora app that suppresses notifications when it's cloudy to avoid fomo :/
about 1 month ago
0
13
1
reposted by
Theo Sanderson
Alan Stedman
about 1 month ago
This photo was taken in 1911 using glass plate technology by Herbert Ponting who was part of Scott's Antarctic expedition, The composition and detail are exquisite with the band of white snow/ice creating a perfect frame around the two people and the ship in the distance Iconic imo
193
14755
3269
my new job: life coach for llms
about 1 month ago
0
10
1
reposted by
Theo Sanderson
Adam Kucharski
about 1 month ago
New post, on how AI is coming for open source software:
kucharski.substack.com/p/will-your-...
loading . . .
Will your favourite open source software tools soon be closed off?
Freely available software relies on credit. AI is destroying that.
https://kucharski.substack.com/p/will-your-favourite-open-source-software
3
40
26
reposted by
Theo Sanderson
Adam Kucharski
about 1 month ago
Want to get the data out of a PDF figure? As in, the actual data – not a rough trace-along-the-lines version? I made an app you might like:
adamkucharski.github.io/pdf2plot/
It all started a few years ago... 🧵
loading . . .
18
477
205
gemini deep research is the most pretentious model out there
about 1 month ago
2
17
5
A policy
@ncsc.gov.uk
specifically advise against
www.ncsc.gov.uk/blog-post/pr...
add a skeleton here at some point
about 1 month ago
1
10
0
Anyone have a good GHA yaml for making claude's code review more like codex? (Less fluff, less compliments!) The below doesn't seem to have done the trick
about 1 month ago
4
4
0
Following accounts like this is probably quite an effective way to convince others to move
add a skeleton here at some point
about 1 month ago
1
12
3
What proportion of new production code for commercial software in 2028 will have been read by a human? 1️⃣
0-10%
2️⃣
10-50%
3️⃣
50%-90%
4️⃣
>90%
📊 Show results
about 1 month ago
2
5
2
reposted by
Theo Sanderson
tachikoma
about 1 month ago
i do feel a bit sad that i can't tell if this is real or not
add a skeleton here at some point
5
20
1
"She and Chen sent GISAID three emails in the weeks after, but never received any response. (GISAID says the emails came from Chen, whereas its agreement was with Stadler.)"
www.science.org/content/arti...
loading . . .
Fresh conflicts erupt around giant database for flu and COVID-19 sequences
Critics say “autocratic” behavior by GISAID could hamper response to a future pandemic
https://www.science.org/content/article/fresh-conflicts-erupt-around-giant-database-flu-and-covid-19-sequences
about 2 months ago
2
19
3
reposted by
Theo Sanderson
Jeffrey Barrett
about 2 months ago
I also got this, but I thought it was kind of interesting, and did their survey to see how well it did (spoiler: it was bad). As I mention in a reply to the OP, I don't see an obvious problem with the research (other than that their AI is bad at doing the thing they want it to do).
add a skeleton here at some point
0
8
1
This seems positive?
add a skeleton here at some point
about 2 months ago
0
8
0
reposted by
Theo Sanderson
Healthcare-Global
about 2 months ago
Global cough radar
sleepcycle.com/coughradar?l...
loading . . .
Cough Radar
Track respiratory health trends with Cough Radar.
https://sleepcycle.com/coughradar?lat=43.720432&lng=-72.597873&zoom=7.00
1
5
7
reposted by
Theo Sanderson
Dr Alex Bond
about 2 months ago
On the first day of Christmas (in about 2014),
@duckswabber.bsky.social
gave to me - a partridge in a pear tree. Happy Christmas everyone!
2
127
46
Bike-couriered by the editor himself. An illustrious publication!
add a skeleton here at some point
about 2 months ago
0
8
2
'Beer stein icons indicate roughly five-day dosing windows'
www.sciencenews.org/article/vacc...
2 months ago
0
10
2
reposted by
Theo Sanderson
Michel Nivard
2 months ago
This smells distinctly like collider bias and/or selection bias and/or regression to the mean... You simply can't select teen prodigies, and world class athletes rom databases, and go run regressions without serious consideration of the selection process!
add a skeleton here at some point
23
340
82
Load more
feeds!
log in