@haanenjohn.bsky.social
π€ 105
π₯ 19
π 0
reposted by
Waggoner Lab
2 months ago
Review
@natrevneph.nature.com
@haanenjohn.bsky.social
Immunological features of clear-cell renal-cell carcinoma and resistance to immune checkpoint inhibitors
www.nature.com/articles/s41...
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Immunological features of clear-cell renal-cell carcinoma and resistance to immune checkpoint inhibitors - Nature Reviews Nephrology
Although immune checkpoint inhibitors can prolong survival in people with clear-cell renal-cell carcinoma, disease progression is frequent. Here, the authors explore potential mechanisms that might dr...
https://www.nature.com/articles/s41581-025-00983-w
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reposted by
Netherlands Cancer Institute
about 2 months ago
Researchers Veer Keizer and
@riklindeboom.bsky.social
have both received a Veni grant from the Dutch Research Council to set up and strengthen their own independent research lines β‘οΈ
www.nki.nl/news-events/...
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reposted by
Nature Biotechnology
5 months ago
The May issue is live
nature.com/nbt/volumes/...
On the cover, a βgreenβ platform for template-independent enzymatic synthesis of RNA oligonucleotides using reversible terminator nucleoside triphosphates that offers a sustainable alternative to traditional chemical methods
go.nature.com/3zBfDZf
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reposted by
Jon Lim, MRCP PhD
6 months ago
Promising results from Ph 1 trial of autologous PRAME-directed TCR-T cell therapy in HLA-A*02+ patients with PRAME+ recurrent and/or refractory solid tumors. Out now in
@naturemedicine.bsky.social
! Enrolment for Ph 3 trial of IMA203 ongoing π
clinicaltrials.gov/study/NCT067...
add a skeleton here at some point
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reposted by
ETH Zurich
6 months ago
In the fight against bacterial pathogens, researchers are combining vaccination with targeted colonisation of the intestine by harmless microorganisms. This approach could potentially mark a turning point in the antibiotics crisis.
ethz.ch/en/news-and-...
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New vaccine concept tackles harmful bacteria in the intestine
In the fight against bacterial pathogens, researchers are combining vaccination with targeted colonisation of the intestine by harmless microorganisms. This approach could potentially mark a turning p...
https://ethz.ch/en/news-and-events/eth-news/news/2025/04/new-vaccine-concept-tackles-harmful-bacteria-in-the-intestine.html
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reposted by
Netherlands Cancer Institute
6 months ago
Check out this insightful animation from
@vanrheenenlab.bsky.social
@oncodeinstitute.bsky.social
visualizing the findings of their recent Nature paper on tumor formation in the breast Paper β‘οΈ
www.nature.com/articles/s41...
More on the paper β‘οΈ
www.nki.nl/news-events/...
#cancerresearch
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Field cancerization
YouTube video by Antoni van Leeuwenhoek
https://youtu.be/GQ9nkRCRqHc
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5
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reposted by
The ASCO Post
6 months ago
New study shows that neoadjuvant durvalumab + chemotherapy could improve outcomes for high-risk upper tract urothelial carcinoma. Explore the latest findings and implications for
#oncology
practice.
ascopost.com/news/april-2...
#ASCO2025
#CancerResearch
#UrothelialCarcinoma
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reposted by
The ASCO Post
7 months ago
Neoadjuvant combination immunotherapy may improve treatment response in head and neck cancer. Using two immunotherapy drugs shows better tumor shrinkage and survival benefits compared to single-agent therapy.
ascopost.com/news/march-2...
0
2
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reposted by
Jon Lim, MRCP PhD
7 months ago
UK π¬π§ contingent at
#SITCSpringScientific25
! What a stimulating meeting - fully dedicated to discussing everything cell therapy for solid tumours. Fantastic faculty & programme + excellent venue! Feeling super inspired! π Thank you
@sitcancer.bsky.social
& the organisers!
@maxjulve.bsky.social
0
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reposted by
Jon Lim, MRCP PhD
7 months ago
Excited to be here in San Diego πΊπΈ for
#SITCSpringScientific25
focussing on cellular therapy for solid tumours. π To kickstart, we hear keynote from
@haanenjohn.bsky.social
@nkinl.bsky.social
sharing experience from academia-led work on TILs - from basic to translational research to clinical trials!
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reposted by
Cassian Yee
7 months ago
Itβs gotten so bad we need a CHART to follow the whiplash firings and re-hirings π€¦π»ββοΈ Who runs a company like this. Much less a country ??
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reposted by
Binaytara
8 months ago
π Our mission is guided by the C.A.R.E. model, focusing on transforming cancer care in underserved communities globally, implementing accessible care and empowering healthcare professionals. πͺ Learn more:
buff.ly/3EtUOkY
#cancer
#nonprofit
#CancerAwareness
#oncology
#healthcare
#globalhealth
0
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reposted by
Eric Topol
8 months ago
New: The largest medical A.I. randomized controlled trial yet performed, enrolling >100,000 women undergoing mammography screening The use of AI led to 29% higher detection of cancer, no increase of false positives, and reduced workload compared with radiologists w/o AI
thelancet.com/journals/lan...
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Screening performance and characteristics of breast cancer detected in the Mammography Screening with Artificial Intelligence trial (MASAI): a randomised, controlled, parallel-group, non-inferiority, ...
The findings suggest that AI contributes to the early detection of clinically relevant breast cancer and reduces screen-reading workload without increasing false positives.
https://thelancet.com/journals/landig/article/PIIS2589-7500(24)00267-X/fulltext
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reposted by
Sophia Wong
9 months ago
Do check out our review on
#celltherapy
toxicities in solid cancers out now on
#ESMO
IO tech!
add a skeleton here at some point
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5
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reposted by
Jon Lim, MRCP PhD
9 months ago
Great to see this out
@naturemedicine.bsky.social
! Exemplar translational research: autologous T cells (blood), expanded to predicted neoAg (Class I+II). Congratulations
@haanenjohn.bsky.social
,
@sklobuch.bsky.social
& team
@nkinl.bsky.social
for once again advancing
#CellTherapy
in solid cancers.
add a skeleton here at some point
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reposted by
Jarushka Naidoo
9 months ago
Can patterns of progression on IO, inform future decisions? -1377pts from 5 ph 3 trials used to create 3 PD risk levels - low (β¬οΈexisting lesions), intermediate (new lesions), high (both) - risk score assoc w post-PD OS across tumors Prognostic, so far
#LCSM
jamanetwork.com/journals/jam...
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Dissection of Progressive Disease Patterns for a Modified Classification for Immunotherapy
This study examines a modified progressive disease classification and its association with postprogression survival in patients treated with atezolizumab across various solid tumors.
https://jamanetwork.com/journals/jamaoncology/article-abstract/2828577
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reposted by
Jon Lim, MRCP PhD
10 months ago
Very proud of my 'partner-in-crime' π for showcasing our
#MANIFESTuk
consortium publicly for the first time at
#ESMOImmuno24
. Go
@zaydtippu.bsky.social
- you are a star! π Excited to get going with delivery in 2025!
@crick.ac.uk
@icrlondon.bsky.social
@cruk-mi.bsky.social
@mcrcnews.bsky.social
add a skeleton here at some point
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8
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reposted by
Denis - The COVID Info Guy
10 months ago
New research shows younger and middle-aged adults have worse long COVID symptoms than older adults "On an average of 10 months after COVID-19 onset, younger (ages 18-44) and middle-aged (ages 45-64) adults had worse neurologic symptoms of long COVID than adults 65 and older."
#LongCOVID
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New research shows younger and middle-aged adults have worse long COVID symptoms than older adults
New study from Northwestern Medicine finds symptoms occurred regardless of mild or severe COVID-19 infection
https://news.nm.org/new-research-shows-younger-and-middle-aged-adults-have-worse-long-covid-symptoms-than-older-adults/
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