@biorxivpreprint.bsky.social Social sensing of infection reprograms peripheral immunity in healthy mice www.biorxiv.org/content/10.6...

A new #ScienceImmunology study shows that mycobacterium tuberculosis can survive within macrophages by binding dectin1 and altering phagosome maturation and autophagy. https://scim.ag/4pqax6f

Happy to share a new preprint from our group. In studying lung T cell responses in humans, we wondered if the method of sampling matters. Here we isolated paired BAL and endobronchial brushing T cells followed by scRNA- and TCR-seq, finding surprising differences #Immunology

An orally active positive allosteric modulator of the human Mas-related G protein–coupled receptor X1 is a potential therapy for neuropathic pain @jhu.edu www.science.org/doi/10.1126/...

Complement-producing adventitial fibroblasts form an IL-33 alarmin hub that maintains ILC2s during airway allergy

Spaceflight alters the immune regulatory functions of neutrophil granulocytes on T lymphocytes @cp-iscience.bsky.social www.cell.com/iscience/ful...

#newPI feels

The fun leaving your body the moment you're done with the science and it's time to get it published

Nature research paper: Architecture of the neutrophil compartment go.nature.com/3KzY1CV

Our cool new paper depicting fibroblasts more than a scaffold during airway allergy. #Il33 #ILC2 #complement

Complement-producing adventitial fibroblasts form an IL-33 alarmin hub that maintains ILC2s during airway allergy @cp-cellreports.bsky.social @atakkatan.bsky.social @hopkinsmedicine.bsky.social www.cell.com/cell-reports...

How a mattress sensor and smartwatch confirmation led to a patient's diagnosis of complete heart block and need for a pacemaker @nejm.org www.nejm.org/doi/full/10....

Thrilled to share that neutrophils produce extra long fibrillar components named proteoglycofili or PGF. PGF are released by living neutrophils and do not contain DNA. They might look like NETs but are not NETs… www.cell.com/cell-reports...

GPR43 in eosinophils suppresses the emergence of pathogenic Siglec-F high neutrophils in allergic airway inflammation in mice @natcomms.nature.com www.nature.com/articles/s41...

New discovery in ulcerative colitis: a bacterial toxin that kills macrophages and increases inflammation, which could be the foundation for a new treatment science.org/doi/10.1126/... science.org/doi/10.1126/... @science.org