Out today in Neurophotonics, we show that cross-talk between the imaging laser and opsin in all-optical experiments can affect response dynamics beyond what has been accounted for. Imaging conditions subthreshold for evoking spikes can accelerate opsin desensitization: doi.org/10.1117/1.NP...

In @elife.bsky.social: A high-resolution, easy-to-build light-sheet microscope for subcellular imaging doi.org/10.7554/eLif...

#fluorescencefriday distribution of microglia in the whole brain

We identified how mechanical forces shape myelin development. The TMEM63A channel in oligodendrocytes converts physical cues into molecular signals that control myelin growth. Oligodendrocyte mechanotransduction channel TMEM63A regulates myelin sheath geometry: Neuron www.cell.com/neuron/fullt...

iGluSnFR4 is now available @natmethods.nature.com www.nature.com/articles/s41... Glutamate indicators with increased sensitivity and tailored deactivation rates 🧪

We are delighted to sponsor both the GRC and GRS meetings, supporting innovative science and the next generation of leaders in basal ganglia research. #CoherentCorp #GRCBasalGanglia

❄️ Now I understand why people rave about Winter Conferences. I attended one last week and am still under the influence of the fantastic conversations, presentations, and mountain views. #neuroscience

On my way to BIOS and Photonics West in San Francisco. There will be many interesting presentations from Coherent (see the list under link below). Pick and choose something to match your interests! See you soon! #BIOS26 #PW26 www.coherent.com/events/photo...

🔬 What’s next for ultrafast laser sources in multiphoton microscopy? Let's meet at BIOS on January 18, 2026 | 3:25 PM - 3:40 PM PST | Room 160 (Moscone South, Upper Mezzanine) and discuss! #BIOS26 #PhotonicsWest #UltrafastLasers #Microscopy #Photonics @spie.org spie.org/photonics-we...

Two-photon imaging of pulsating brain activity in a #zebrafish larva that's having a seizure. Credit to Dr. Dominic Burrows. #ZebrafishZunday 🧪

You noticed ChatGPT!! Thanks!

Applying for faculty jobs this cycle? Check out our latest special episode! @moeneuro.bsky.social and @drnancypadilla.bsky.social discuss when to apply, important considerations when preparing applications, and more! Listen below! www.storiesofwin.org/profiles/202... #AcademicBluesky #NeuroJobs

I’m already in San Diego and participating first-hand in a bunch of exciting #sfn25 satellite events!

If you are attending #SfN25, please join @amygleichman.bsky.social and I on Monday at 9PM for a casual social gathering to discuss all things non-neuronal! Date: Monday, Nov 17th Time: 9PM till close Location: The Smoking Gun SD, 555 Market St. All welcome, please free to spread the word!

#SfN25 is packed with amazing science and networking opportunities. Cannot wait! The power of coming together has never been more important. #Neuroscience #Microscopy #2Photon #3Photon #1Photon

💜 Great day at Harvard Medical School! Don't be sorry if you missed the workshop, customers presentations and tech talks. Reach out with questions.

🚀 Join us at Harvard Med! Discover how miniature multiphoton imaging is enabling neuroscience in freely moving animals. 🧠 Miniature Multiphoton Systems for Neuroscience Workshop 📍 Warren Alpert 236, 220 Longwood Ave 📅 Oct 27 | 12:00–15:00

How does the brain balance learning new things without overwriting what it already knows? Our new paper tackles this long-standing stability–plasticity dilemma during active navigation. With Tony Drinnenberg from the Deisseroth Lab (@deisseroth.bsky.social) doi.org/10.1101/2025...

"There's no shortage of reasons these days to be angry or afraid. But look around you right now and you'll see tens of thousands of reasons to keep the faith and keep going. This is the America we know to be possible." —Mayor Michelle Wu, Boston No Kings Rally 🚫👑 #NoKings

The microscopy core at Miami University is searching for a new director. Please consider sharing this job posting! miamioh.wd5.myworkdayjobs.com/en-US/miamio...

‘Economics Nobel prize won by researchers who showed how science boosts growth’ by @philipcball.bsky.social in @nature.com www.nature.com/articles/d41...

Check this out if you're interested in causal neuroscience and/or brain-machine interfaces www.cell.com/cell-reports...

#fluorescencefriday shows the intimate relationship between astrocytes, (cyan) microglia (green) and amyloid plaques (magenta). we find that in APOE4 mice there is much more glia associated with plaques.

Fall and a tail 🐾🐕‍🦺

And we're off to a nice start of #OMIBS2025 Pictures feature course directors @michelleitano.bsky.social and Wes Legant introducing the course and our generous sponsors @leicamicrosystems.bsky.social Evident/Olympus @abberior.rocks Coherent @pacificoptica.bsky.social (1/3)

Enjoy wide two-photon view lighted with Axon 920, 1.2 W

Just landed in Woods Hole for summer courses: a Full Ventana Wide system. pacificoptica.com/ventana/ with a Cousa pacificoptica.com/cousa/ www.mbl.edu/education/ad... www.mbl.edu/education/ad... Thanks, Coherent! Thanks, MBF! Thanks to course leadership and MBL staff!

#OCaMP is now on bioRxiv and reagents are available on #Addgene! 🧪 A sensitive orange fluorescent calcium ion indicator for imaging neural activity www.biorxiv.org/content/10.1...

The Queen 🇵🇱

Exploring the Brain - One Spine at a Time 🔬 Just chatted with @sainsburywellcome.bsky.social about our latest work, miniaturising two-photon microscopy for neuroscience at @kavlintnu.bsky.social www.sainsburywellcome.org/web/qa/mini-... A few highlights:

Good morning from Maine! #conference

Very nice nature review on emerging three-photon microscopy!

Going East, again this summer.

Beautiful Saturday

Absolutely gorgeous both shape and color palette

A nice z-stack through cortical layers containing plaques and structures that express vimentin, a cytoskeletal protein. #microscopy #neuroscience #2Photon #fluorescence

We're having a great time at @mblscience.bsky.social Neurobiology, and @nsb-mbl.bsky.social courses! This time excited to showcase multiphoton microscope from Sutter, powered by the Chameleon Discovery LX femtosecond laser from Coherent Corp. #microscopy #neuroscience #2Photon #STEM

Proud to support the next generation of imaging scientists. Here are a few shots of Coherent's ultrafast fixed-wavelength Axon lasers at 780, 920, and 1064 nm, lighting Thorlabs scope-ready for student prepared samples at @mblscience.bsky.social. #Microscopy #Neuroscience #UltrafastLasers #STEM

I told you 🫵

It's officially published!! In my main postdoc work with @markplitt.bsky.social and @lgiocomo.bsky.social, we found that the hippocampus simultaneously encodes an animal's spatial position and its experience relative to reward in parallel population codes. 🧵 www.nature.com/articles/s41...

Our favorite pine trees on our daily walk

Hey! I’ll be in the Boston area next week and at MBL consulting on imaging technologies. If you're using multiphoton microscopy in your research, I'd love to hear about your applications and share some of the latest laser developments from Coherent. Send me a msg.

Loved the @neurophotonics.bsky.social summer school, Quebec City and French people. Also got in touch with some people I’ve been meaning to connect with for a while!!

On the plane next to a guy with a running nose. It hurts my ears. Offered a tissue to him but he refused and warned me to continue making the noise.

Here come our new palette of fluorescent dyes. The BD dyes endeaves to balance glowy brightness, robust photostability, and biocompatibility. Let's boost 4D dynamic super-resolution imaging!!! www.nature.com/articles/s41... @spirochrome.com

I'm looking forward to attending, even if just briefly, the 18th Edition of the Frontiers in @neurophotonics.bsky.social Summer School this week at the CERVO Brain Research Center in Quebec City. I have a few openings on Wednesday (June 4). Let me know if you'd like to catch up or show me around!

It is out! Read how you achieve 1.7 mm deep 3-photon imaging in prefrontal cortex with dendritic spine resolution over a week. www.nature.com/articles/s42...

I urge everyone to read Unbreaking’s new page on everything the govt is doing to destroy & diminish medical research funding. It’s the best thing I’ve read on this topic: @lizneeley.bsky.social & co have such done an incredible job. unbreaking.org/issues/medic...

Not going well... lots of fruits but leaves are affected by disease caused by the fungus Taphrina deformans 😭

Heartbroken to hear that the @hhmi.org Hanna Grey fellowship competition is being cancelled this year. I poured so much work and creativity into this app and am very grateful for everyone who helped me revise. It is such a difficult time to be a young scientist.