Ewa Zarnowska
@ewadorotaz.bsky.social
📤 701
📥 1582
📝 92
Ph.D. | Ex-Neuro & Ephys | Microscopes & Lasers | Coherent Corp. | Opinions mine
reposted by
Ewa Zarnowska
Blake Russell
17 days ago
Out today in Neurophotonics, we show that cross-talk between the imaging laser and opsin in all-optical experiments can affect response dynamics beyond what has been accounted for. Imaging conditions subthreshold for evoking spikes can accelerate opsin desensitization:
doi.org/10.1117/1.NP...
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https://doi.org/10.1117/1.NPh.13.1.015007
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reposted by
Ewa Zarnowska
Kevin Dean
7 days ago
In
@elife.bsky.social
: A high-resolution, easy-to-build light-sheet microscope for subcellular imaging
doi.org/10.7554/eLif...
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A high-resolution, easy-to-build light-sheet microscope for subcellular imaging
An accessible light-sheet microscope delivers subcellular-resolution, multicolor volumetric, and live-cell imaging, lowering barriers to state-of-the-art performance.
https://doi.org/10.7554/eLife.106910
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reposted by
Ewa Zarnowska
Marco A. Maximo Prado
7 days ago
#fluorescencefriday
distribution of microglia in the whole brain
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reposted by
Ewa Zarnowska
Amit Agarwal
about 1 month ago
We identified how mechanical forces shape myelin development. The TMEM63A channel in oligodendrocytes converts physical cues into molecular signals that control myelin growth. Oligodendrocyte mechanotransduction channel TMEM63A regulates myelin sheath geometry: Neuron
www.cell.com/neuron/fullt...
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Oligodendrocyte mechanotransduction channel TMEM63A regulates myelin sheath geometry
Dereddi, Djannatian, and colleagues show that oligodendrocytes use mechanical cues to measure axon size. The stretch-activated channel TMEM63A converts membrane tension into calcium signals, which cal...
https://www.cell.com/neuron/fulltext/S0896-6273%2825%2900856-6
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reposted by
Ewa Zarnowska
Abhi Aggarwal
about 2 months ago
iGluSnFR4 is now available
@natmethods.nature.com
www.nature.com/articles/s41...
Glutamate indicators with increased sensitivity and tailored deactivation rates 🧪
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Glutamate indicators with increased sensitivity and tailored deactivation rates - Nature Methods
iGluSnFR4f and iGluSnFR4s are the latest generation of genetically encoded glutamate sensors. They are advantageous for detecting rapid dynamics and large population activity, respectively, as demonst...
https://www.nature.com/articles/s41592-025-02965-z
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We are delighted to sponsor both the GRC and GRS meetings, supporting innovative science and the next generation of leaders in basal ganglia research.
#CoherentCorp
#GRCBasalGanglia
7 days ago
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❄️ Now I understand why people rave about Winter Conferences. I attended one last week and am still under the influence of the fantastic conversations, presentations, and mountain views.
#neuroscience
8 days ago
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On my way to BIOS and Photonics West in San Francisco. There will be many interesting presentations from Coherent (see the list under link below). Pick and choose something to match your interests! See you soon!
#BIOS26
#PW26
www.coherent.com/events/photo...
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Photonics West 2026
Photonics West is the premier photonics and laser exhibition featuring the latest advances in lasers, biomedical optics, optoelectronics, and more.
https://www.coherent.com/events/photonics-west
28 days ago
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🔬 What’s next for ultrafast laser sources in multiphoton microscopy? Let's meet at BIOS on January 18, 2026 | 3:25 PM - 3:40 PM PST | Room 160 (Moscone South, Upper Mezzanine) and discuss!
#BIOS26
#PhotonicsWest
#UltrafastLasers
#Microscopy
#Photonics
@spie.org
spie.org/photonics-we...
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https://spie.org/photonics-west/presentation/New-generation-of-lasers-for-nonlinear-microscopy/13856-10
about 1 month ago
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reposted by
Ewa Zarnowska
Zebrafish Rock!
2 months ago
Two-photon imaging of pulsating brain activity in a
#zebrafish
larva that's having a seizure. Credit to Dr. Dominic Burrows.
#ZebrafishZunday
🧪
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You noticed ChatGPT!! Thanks!
about 2 months ago
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reposted by
Ewa Zarnowska
Stories of WiN
4 months ago
Applying for faculty jobs this cycle? Check out our latest special episode!
@moeneuro.bsky.social
and
@drnancypadilla.bsky.social
discuss when to apply, important considerations when preparing applications, and more! Listen below!
www.storiesofwin.org/profiles/202...
#AcademicBluesky
#NeuroJobs
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Applying to faculty jobs 101 — Stories of WiN
This episode features Dr. Monique Smith (Assistant Professor, UCSD) discussing faculty job applications with host Dr. Nancy Padilla-Coreano.
https://www.storiesofwin.org/profiles/2025/10/16/faculty-job-applications
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I’m already in San Diego and participating first-hand in a bunch of exciting
#sfn25
satellite events!
3 months ago
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reposted by
Ewa Zarnowska
Wendy Xin
4 months ago
If you are attending
#SfN25
, please join
@amygleichman.bsky.social
and I on Monday at 9PM for a casual social gathering to discuss all things non-neuronal! Date: Monday, Nov 17th Time: 9PM till close Location: The Smoking Gun SD, 555 Market St. All welcome, please free to spread the word!
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#SfN25
is packed with amazing science and networking opportunities. Cannot wait! The power of coming together has never been more important.
#Neuroscience
#Microscopy
#2Photon
#3Photon
#1Photon
4 months ago
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💜 Great day at Harvard Medical School! Don't be sorry if you missed the workshop, customers presentations and tech talks. Reach out with questions.
add a skeleton here at some point
4 months ago
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🚀 Join us at Harvard Med! Discover how miniature multiphoton imaging is enabling neuroscience in freely moving animals. 🧠 Miniature Multiphoton Systems for Neuroscience Workshop 📍 Warren Alpert 236, 220 Longwood Ave 📅 Oct 27 | 12:00–15:00
4 months ago
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reposted by
Ewa Zarnowska
Alex
4 months ago
How does the brain balance learning new things without overwriting what it already knows? Our new paper tackles this long-standing stability–plasticity dilemma during active navigation. With Tony Drinnenberg from the Deisseroth Lab (
@deisseroth.bsky.social
)
doi.org/10.1101/2025...
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Environmental Novelty Modulates Rapid Cortical Plasticity During Navigation
In novel environments, animals quickly learn to navigate, and position-correlated spatial representations rapidly emerge in both the retrosplenial cortex (RSC) and primary visual cortex (V1). However,...
https://doi.org/10.1101/2025.10.21.683723
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reposted by
Ewa Zarnowska
Sarah
4 months ago
"There's no shortage of reasons these days to be angry or afraid. But look around you right now and you'll see tens of thousands of reasons to keep the faith and keep going. This is the America we know to be possible." —Mayor Michelle Wu, Boston No Kings Rally 🚫👑
#NoKings
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reposted by
Ewa Zarnowska
Dr. Anna Radke
4 months ago
The microscopy core at Miami University is searching for a new director. Please consider sharing this job posting!
miamioh.wd5.myworkdayjobs.com/en-US/miamio...
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Director of the Center for Advanced Microscopy and Imaging
Job Title Director of the Center for Advanced Microscopy and Imaging Department Biology Department JM Worker Type Regular Pay Type Salary Position Salary Minimum $60,000 Position Salary Maximum $75,00...
https://miamioh.wd5.myworkdayjobs.com/en-US/miamioh-staff/job/Director-of-the-Center-for-Advanced-Microscopy-and-Imaging_JR103099
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reposted by
Ewa Zarnowska
Stu Cantrill
4 months ago
‘Economics Nobel prize won by researchers who showed how science boosts growth’ by
@philipcball.bsky.social
in
@nature.com
www.nature.com/articles/d41...
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reposted by
Ewa Zarnowska
Arnd Roth
5 months ago
Check this out if you're interested in causal neuroscience and/or brain-machine interfaces
www.cell.com/cell-reports...
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A real-time all-optical interface for dynamic perturbation of neural activity during behavior
Zhang et al. develop a system that reads activity from individual neurons in real time and uses holographic light patterns to control specific neurons in mice, enabling automated, all-optical experime...
https://www.cell.com/cell-reports-methods/fulltext/S2667-2375(25)00216-4
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reposted by
Ewa Zarnowska
Marco A. Maximo Prado
4 months ago
#fluorescencefriday
shows the intimate relationship between astrocytes, (cyan) microglia (green) and amyloid plaques (magenta). we find that in APOE4 mice there is much more glia associated with plaques.
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Fall and a tail 🐾🐕🦺
5 months ago
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reposted by
Ewa Zarnowska
OMIBS @ MBL
6 months ago
And we're off to a nice start of
#OMIBS2025
Pictures feature course directors
@michelleitano.bsky.social
and Wes Legant introducing the course and our generous sponsors
@leicamicrosystems.bsky.social
Evident/Olympus
@abberior.rocks
Coherent
@pacificoptica.bsky.social
(1/3)
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Enjoy wide two-photon view lighted with Axon 920, 1.2 W
add a skeleton here at some point
6 months ago
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reposted by
Ewa Zarnowska
Pacific Optica
7 months ago
Just landed in Woods Hole for summer courses: a Full Ventana Wide system.
pacificoptica.com/ventana/
with a Cousa
pacificoptica.com/cousa/
www.mbl.edu/education/ad...
www.mbl.edu/education/ad...
Thanks, Coherent! Thanks, MBF! Thanks to course leadership and MBL staff!
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reposted by
Ewa Zarnowska
Abhi Aggarwal
7 months ago
#OCaMP
is now on bioRxiv and reagents are available on
#Addgene
! 🧪 A sensitive orange fluorescent calcium ion indicator for imaging neural activity
www.biorxiv.org/content/10.1...
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A sensitive orange fluorescent calcium ion indicator for imaging neural activity
Genetically encoded calcium indicators (GECIs) are vital tools for fluorescence-based visualization of neuronal activity with high spatial and temporal resolution. However, current highest-performance...
https://www.biorxiv.org/content/10.1101/2025.07.28.667269v1
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The Queen 🇵🇱
add a skeleton here at some point
7 months ago
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reposted by
Ewa Zarnowska
Weijian Zong
7 months ago
Exploring the Brain - One Spine at a Time 🔬 Just chatted with
@sainsburywellcome.bsky.social
about our latest work, miniaturising two-photon microscopy for neuroscience at
@kavlintnu.bsky.social
www.sainsburywellcome.org/web/qa/mini-...
A few highlights:
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Good morning from Maine!
#conference
add a skeleton here at some point
7 months ago
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Very nice nature review on emerging three-photon microscopy!
add a skeleton here at some point
7 months ago
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Going East, again this summer.
7 months ago
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Beautiful Saturday
7 months ago
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Absolutely gorgeous both shape and color palette
add a skeleton here at some point
8 months ago
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A nice z-stack through cortical layers containing plaques and structures that express vimentin, a cytoskeletal protein.
#microscopy
#neuroscience
#2Photon
#fluorescence
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8 months ago
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We're having a great time at
@mblscience.bsky.social
Neurobiology, and
@nsb-mbl.bsky.social
courses! This time excited to showcase multiphoton microscope from Sutter, powered by the Chameleon Discovery LX femtosecond laser from Coherent Corp.
#microscopy
#neuroscience
#2Photon
#STEM
8 months ago
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Proud to support the next generation of imaging scientists. Here are a few shots of Coherent's ultrafast fixed-wavelength Axon lasers at 780, 920, and 1064 nm, lighting Thorlabs scope-ready for student prepared samples at
@mblscience.bsky.social
.
#Microscopy
#Neuroscience
#UltrafastLasers
#STEM
8 months ago
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I told you 🫵
add a skeleton here at some point
8 months ago
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reposted by
Ewa Zarnowska
Mari Sosa
8 months ago
It's officially published!! In my main postdoc work with
@markplitt.bsky.social
and
@lgiocomo.bsky.social
, we found that the hippocampus simultaneously encodes an animal's spatial position and its experience relative to reward in parallel population codes. 🧵
www.nature.com/articles/s41...
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A flexible hippocampal population code for experience relative to reward - Nature Neuroscience
Sosa et al. find that hippocampal neural activity in mice encodes both environmental location and experience relative to rewards, spanning distances far from reward, through parallel and flexible popu...
https://www.nature.com/articles/s41593-025-01985-4
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Our favorite pine trees on our daily walk
8 months ago
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Hey! I’ll be in the Boston area next week and at MBL consulting on imaging technologies. If you're using multiphoton microscopy in your research, I'd love to hear about your applications and share some of the latest laser developments from Coherent. Send me a msg.
8 months ago
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Loved the
@neurophotonics.bsky.social
summer school, Quebec City and French people. Also got in touch with some people I’ve been meaning to connect with for a while!!
add a skeleton here at some point
8 months ago
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On the plane next to a guy with a running nose. It hurts my ears. Offered a tissue to him but he refused and warned me to continue making the noise.
9 months ago
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reposted by
Ewa Zarnowska
Zhixing Chen
9 months ago
Here come our new palette of fluorescent dyes. The BD dyes endeaves to balance glowy brightness, robust photostability, and biocompatibility. Let's boost 4D dynamic super-resolution imaging!!!
www.nature.com/articles/s41...
@spirochrome.com
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A palette of bridged bicycle-strengthened fluorophores - Nature Methods
A suite of bridged rhodamine dyes (BriDyes) offers excellent brightness, solubility, photostability, and tunable cell permeability along with resistance to photoblueing, making them exceptional all-pu...
https://www.nature.com/articles/s41592-025-02693-4
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I'm looking forward to attending, even if just briefly, the 18th Edition of the Frontiers in
@neurophotonics.bsky.social
Summer School this week at the CERVO Brain Research Center in Quebec City. I have a few openings on Wednesday (June 4). Let me know if you'd like to catch up or show me around!
9 months ago
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reposted by
Ewa Zarnowska
Martin Fuhrmann
9 months ago
It is out! Read how you achieve 1.7 mm deep 3-photon imaging in prefrontal cortex with dendritic spine resolution over a week.
www.nature.com/articles/s42...
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Three-photon in vivo imaging of neurons and glia in the medial prefrontal cortex with sub-cellular resolution - Communications Biology
Three-photon in vivo imaging provides access to medial prefrontal cortex, hippocampus and spinal cord in mice at up to 1.7 mm depth of neurons, dendrites, spines, astrocytes and microglia.
https://www.nature.com/articles/s42003-025-08079-8
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reposted by
Ewa Zarnowska
Ed Yong
9 months ago
I urge everyone to read Unbreaking’s new page on everything the govt is doing to destroy & diminish medical research funding. It’s the best thing I’ve read on this topic:
@lizneeley.bsky.social
& co have such done an incredible job.
unbreaking.org/issues/medic...
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Medical Research Funding — Unbreaking
How the administration is breaking the government, and what that means for all of us.
https://unbreaking.org/issues/medical-research-funding/
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Not going well... lots of fruits but leaves are affected by disease caused by the fungus Taphrina deformans 😭
add a skeleton here at some point
9 months ago
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reposted by
Ewa Zarnowska
Audrey Drotos, PhD 🧠 🔬
9 months ago
Heartbroken to hear that the
@hhmi.org
Hanna Grey fellowship competition is being cancelled this year. I poured so much work and creativity into this app and am very grateful for everyone who helped me revise. It is such a difficult time to be a young scientist.
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