Charlie Gilbert
@charliegilbert.bsky.social
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Principal Scientist at Cultivarium
reposted by
Charlie Gilbert
bioRxiv Synthetic Biology
18 days ago
A genetic platform for a biocementation bacterium
https://www.biorxiv.org/content/10.64898/2025.12.05.692644v1
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Charlie Gilbert
Alex Crits-Christoph
about 1 month ago
Very happy to share our recent work
@cultivarium.bsky.social
on genetic tools for Ideonella sakaiensis, a (Betaproteo-)bacterium that degrades PET plastic. We identified a plasmid vector for the strain and generated a large RB-TnSeq library, screening for genes impacting plastic degradation.
add a skeleton here at some point
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Charlie Gilbert
The Westerdijk Fungal Biodiversity Institute
7 months ago
The dimorphic, yeast-like, extremophilic genus Aureobasidium is revised, and show to include ca 40 species, of which nine are newly described here. Species cause opportunistic diseases in humans, but several have also shown to be well-established plant pathogens.
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Charlie Gilbert
Tom Ellis
8 months ago
My dept in London at Imperial (Bioengineering) is recruiting a group leader at Professor level 🧑🎓 Please RT. It's a great place with world-class expertise in all sorts of biomedical & biological engineering topics like synthetic biology. It's also not in the USA.
www.imperial.ac.uk/jobs/search-...
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Charlie Gilbert
Nature Microbiology
8 months ago
Quick Read! Read the News and Views piece describing the physiological importance of an extended bacterial androgen production pathway
#MicroSky
🦠
www.nature.com/articles/s41...
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Linking bacterial androgen production and prostate cancer - Nature Microbiology
Commensal bacteria, including those isolated from urinary tract and prostate tissues, encode enzymes to convert androstenedione to epitestosterone, expanding our knowledge of microbial steroid metabol...
https://www.nature.com/articles/s41564-025-01996-8?utm_source=bluesky&utm_medium=social&utm_campaign=nmicrobiol
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Charlie Gilbert
Cultivarium
8 months ago
We're gearing up to tackle new kingdoms of life, thanks to generous support from
@wellcometrust.bsky.social
. Get in touch! Read more on our blog:
cultivarium.substack.com/p/fungi-and-...
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Charlie Gilbert
Convergent Research
9 months ago
"There are bottlenecks choking progress in virtually every scientific field, and you can identify these with a good roadmap." -
@adammarblestone.bsky.social
Out now on our new Substack, Essential Technology:
convergentresearch.substack.com/p/scientific...
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A beginner’s guide to scientific roadmapping
Wonderful maps and how to read them
https://convergentresearch.substack.com/p/scientific-roadmapping
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The insertion of the inverted repeat of an insertion sequence (IS) element from Lacticaseibacillus rhamnosus changes the host range and stability of pGK12, a shuttle vector for lactic acid bacteria | Applied and Environmental Microbiology
journals.asm.org/doi/10.1128/...
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The insertion of the inverted repeat of an insertion sequence (IS) element from Lacticaseibacillus rhamnosus changes the host range and stability of pGK12, a shuttle vector for lactic acid bacteria | ...
This study highlights the significant impact of insertion sequence (IS) elements on plasmid replication in lactobacilli. The spontaneous integration of an IS element from the Laticaseibacillus rhamnos...
https://journals.asm.org/doi/10.1128/aem.01908-24?utm_source=literatum&utm_medium=email&utm_campaign=alert-emails
9 months ago
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reposted by
Charlie Gilbert
Nick Kristof
10 months ago
Elon Musk says that no one has died because he slashed humanitarian aid. I went to South Sudan to check if that's true. It's not. Meet Peter, Achol and Evan, ages 10, 8 and 5. The reckless actions of the world's richest men are killing the world's poorest kids
www.nytimes.com/interactive/...
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Opinion | Musk Said No One Has Died Since Aid Was Cut. That Isn’t True. (Gift Article)
A journey through the front lines of global poverty shows that when the world’s richest men slash aid for the world’s poorest children, the result is sickness, starvation and death.
https://www.nytimes.com/interactive/2025/03/15/opinion/foreign-aid-cuts-impact.html?unlocked_article_code=1.4E4.H8Lx.GD39rucUfloD&smid=url-share
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Charlie Gilbert
ASM
10 months ago
This
#WomensHistoryMonth
, ASM celebrates the achievements and contributions of women scientists to the field of microbiology. Explore our curated resources:
asm.social/2jz
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Charlie Gilbert
IMA Fungus
10 months ago
This review of fungal fairy rings explores their history, ecology, and engineering impact on ecosystems.
@pensoft.net
blog post:
blog.pensoft.net/2025/03/06/f...
Review article:
doi.org/10.3897/imaf...
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Fungal Fairy Rings: the science behind the magic
An article published in the journal IMA Fungus sheds light on fungal fairy rings, exploring the history, ecology, and impacts of these formations.
https://blog.pensoft.net/2025/03/06/fungal-fairy-rings-the-science-behind-the-magic/
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Charlie Gilbert
Vivek Mutalik
10 months ago
Made a feed for phage papers/discussions/friends! Please feel free to pin this feed to your bluesky profile and if you wish to add to the feed, simply add the
#phage
hashtag (NOT case sensitive) and the feed will aggregate the posts. See you there! Please repost🙏🏽
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So THAT'S what my washing machine plays when it's finished a cycle!
add a skeleton here at some point
10 months ago
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Charlie Gilbert
ASM
10 months ago
ASM encourages our members to advocate for their research and for the microbial sciences. On Friday, March 7, there will be a rally to
#standupforscience2025
in Washington, D.C. and more than 30 other locations nationwide. For information and updates, visit:
standupforscience2025.org?trk=feed-det...
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A call for healing and unity | Applied and Environmental Microbiology
journals.asm.org/doi/10.1128/...
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A call for healing and unity | Applied and Environmental Microbiology
Executive orders signed since 20 January 2025 aim to end programs intended to diversify the scientific workforce via equitable and inclusive practices and processes; cut federal funding for research a...
https://journals.asm.org/doi/10.1128/aem.00448-25?utm_source=literatum&utm_medium=email&utm_campaign=alert-emails
10 months ago
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Oh this sounds fun!
add a skeleton here at some point
10 months ago
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mSphere of Influence: The maternal gut–mammary axis and its role in shaping neonatal health | mSphere
journals.asm.org/doi/10.1128/...
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mSphere of Influence: The maternal gut–mammary axis and its role in shaping neonatal health | mSphere
In high school, I worked on a dairy farm, milking cows and caring for calves to save money for college. It was there that I first observed the critical link between milk quality and neonatal health. In dairy cows, maternal immunity, in the form of immunoglobulins, is fully transferred through colostrum—the mother’s first milk—during the first 24 to 48 hours of life (1). I witnessed how low immunoglobulin levels in colostrum compromised a calf’s ability to fight infectious diseases. These experiences sparked my curiosity about breast milk immunity and inspired me to pursue a career exploring the intersection of maternal health and infectious disease.
https://journals.asm.org/doi/10.1128/msphere.00556-24?utm_source=literatum&utm_medium=email&utm_campaign=alert-emails
10 months ago
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Deployment of a Vibrio cholerae ordered transposon mutant library in a quorum-competent genetic background | mBio
journals.asm.org/doi/10.1128/...
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Deployment of a Vibrio cholerae ordered transposon mutant library in a quorum-competent genetic background | mBio
Vibrio cholerae is a human pathogen and the causative agent of the acute diarrheal disease cholera. While cholera is a global threat, the disease is endemic in developing countries, where it is estima...
https://journals.asm.org/doi/10.1128/mbio.00036-25?utm_source=literatum&utm_medium=email&utm_campaign=alert-emails
10 months ago
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reposted by
Charlie Gilbert
We make molecules!
10 months ago
Our PhD student Adrian Gadar López and the Black Yeast Natural Products team made fungal PKS Heterologous Expression easy! Check out the preprint.
www.researchsquare.com/article/rs-6...
#wemakemolecules
#blackyeast
#NNF_BRIGHT
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Black yeasts are efficient heterologous hosts of a wide range of fungal polyketides
Fungal natural products, including polyketides, are a rich source of bioactive molecules. Their biosynthetic enzymes are encoded within biosynthetic gene clusters, which are often activated by specifi...
https://www.researchsquare.com/article/rs-6001933/v1
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Charlie Gilbert
Liz Koziol
10 months ago
Teaching the Arbuscular Mycorrhizal Fungi lab next week at
@universityofkansas.bsky.social
! I’ve prepped spores from ten different species to showcase the diversity in color, shape, and size. Fungal diversity is truly beautiful! 🍄🧪🦠🌏 Huge thanks to
@invam.bsky.social
for donating the materials!
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Charlie Gilbert
Kew Gardens
10 months ago
Missing the fungal forays of Autumn? Winter and Spring offer a myriad of wonderful fungal species in their prime! Frequently overlooked are the ascomycetes, commonly called cup fungi as they form cup-like fruiting bodies named apothecia. Here are some of our favourite species to look out for ✨🍄🧵
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reposted by
Charlie Gilbert
Asaf Levy
11 months ago
We had an inspiring talk by
@delafuentelab.bsky.social
on antibiotic discovery using AI, as part of the Microbiology Journal Club. Feel free to email me if you want to be included in the mailing list and get exposure to amazing science.
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Charlie Gilbert
Matthew Sims
11 months ago
Although I was not given funding to publish this OA, if anyone (or any one that you know) would like a pdf of the book, shoot me a message. I'd be more than happy to send it your way.
www.cambridge.org/core/element...
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Slime Mould and Philosophy
Cambridge Core - Philosophy: General Interest - Slime Mould and Philosophy
https://www.cambridge.org/core/elements/abs/slime-mould-and-philosophy/8A2DAE326F52566472C6A85C055A3580?utm_campaign=shareaholic&utm_medium=twitter&utm_source=socialnetwork
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Charlie Gilbert
Bind Research
11 months ago
We’re thrilled to announce the launch of Bind Research, the UK’s first not-for-profit Focused Research Organisation, with long-term support from the Department for Science, Innovation and Technology’s Research Ventures Catalyst Programme, industry, and charities.
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Charlie Gilbert
Quadram Institute
11 months ago
🧵📣On International Day of Women and Girls in Science, we’re shining a light on some of the amazing female scientists carrying out research at the intersection of food, microbes and health here at the Quadram Institute⤵️
#InternationalDayofWomenandGirlsinScience
#WomenInScience
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Charlie Gilbert
Douglas Natelson
11 months ago
🧪⚛️ Holy cow. Threats to layoff 25-50% of NSF (!!!). This would be a complete disaster. Anyone who thinks cutting the workforce at a $9B/yr agency by this much will lead to greater efficiency is just out of their mind.
www.politico.com/news/2025/02...
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Science funding agency threatened with mass layoffs
National Science Foundation staff heard the plans at a meeting Tuesday.
https://www.politico.com/news/2025/02/04/science-funding-agency-layoffs-threat-00202426
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Charlie Gilbert
Adam Marblestone
11 months ago
🔒 How can we make AI not just smarter, but safer? 💡Share your boldest FRO ideas & tag someone shaping the future of safe AI!
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https://www.convergentresearch.org/frost-uk⤵️
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When life gives you lemons!
journals.asm.org/doi/10.1128/...
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Not all is lost: resilience of microbiome samples to freezer failures and long-term storage | mSphere
Microbiome studies heavily rely on ultracold freezers for sample storage. Unfortunately, these freezers are prone to frequent malfunctions, resulting in the loss of invaluable samples at laboratories ...
https://journals.asm.org/doi/10.1128/msphere.00603-24?utm_source=literatum&utm_medium=email&utm_campaign=alert-emails
11 months ago
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Nice idea! Looking forward to more of these:
journals.asm.org/doi/10.1128/...
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The Story behind the Science: Shining a light on the path to discovery | mBio
Researchers turn to scientific literature to inform themselves and stay up to date on the newest developments in their field by reading research articles and reviews. They also contribute to the body ...
https://journals.asm.org/doi/10.1128/mbio.03679-24
11 months ago
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reposted by
Charlie Gilbert
The Dunn School, Oxford
11 months ago
ICYMI We are recruiting a new Associate Professor in cell and molecular biology, with a preference for immunology, inflammation and/or infection - all defined broadly Come and be our colleague! Deadline 28 Feb, please spread the word!
www.path.ox.ac.uk/vacancy/asso...
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Charlie Gilbert
RCSB Protein Data Bank
11 months ago
January's Molecule of the Month by @jiwasa.bsky.social includes an animation of polyketide synthesis in action Watch at PDB-101:
pdb101.rcsb.org/motm...
Video created in collaboration with Georgios Skiniotis
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Are British <> American word differences concentrated in the world of baby stuff? Dummy, nappy, pram and cot!
11 months ago
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Charlie Gilbert
kinoko-mono
12 months ago
👄👄👄
#地衣類
#lichen
#fungifriends
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Charlie Gilbert
Adam Marblestone
12 months ago
🚀 Calling all visionary scientists and engineers! Announcing our call for Focused Research Organization proposals in the UK. 🔬Submit your concept paper by Feb 7 & full proposal by March 28. More here:
www.convergentresearch.org/frost-uk
⤵️
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FROST UK — Convergent Research
https://www.convergentresearch.org/frost-uk
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Charlie Gilbert
Innovative Genomics Institute
about 1 year ago
Seedless berries, avocados that don't go brown, cows with a genetic haircut, and more – learn about how CRISPR 🧬 is being used in plant 🌾 & animal 🐮 agriculture in our reader-friendly review, written by IGI's Tonio Chaparro! Read here:
ow.ly/KLMJ50UpjA7
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Charlie Gilbert
Andrew Payne
about 1 year ago
🧪 E11 Bio is excited to share a major step towards brain mapping at 100x lower cost, making whole-brain connectomics at human & mouse scale feasible (🧠→🔬→💻). Critical for curing brain disorders, building human-like AI systems, and even simulating human brains. Read more:
e11.bio/news/roadmap
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