Some #Pseudomonas aeruginosa strains naturally lack the major virulence system T3SS. 🦠 @inaattree.bsky.social & @cbuch.bsky.social labs reveal that avirulent isolates still produce valuable metabolites (e.g. rhamnolipids, elastase, pyoverdine)—making them promising for #biotech use. buff.ly/JST7ZR1

So happy to share this! Bacteriocins were first discovered over 100 years ago, but what do they actually do? We look at >1000 bacteriocin plasmids and find links to virulence and antimicrobial resistance, and frequent bacteriocin sharing in Enterobacteriaceae. www.nature.com/articles/s41...

Rare disease research needs a more integrated and collaborative approach. Next week, experts from across our 4 Translational Centres for Rare Disease, will meet to discuss the year's progress, share knowledge, and discuss the challenges and opportunities to come.

Great kick off meeting for the Precision CF Innovation Hub @imperialnhli.bsky.social @janedaviescf.bsky.social. Awesome talks and a real energy. Thanks to funders @lifearc.bsky.social and @cysticfibrosis.org.uk

New in JB: Bhattacharya, Zhang, & Yu review the current state of knowledge around protein trafficking across the membrane by gram-positive bacteria with a focus on the model organisms Bacillus subtilis and Staphylococcus aureus. journals.asm.org/doi/10.1128/... @asm.org #JBacteriology

Today is #WorldPhageDay! One of our key aims is to advance #phagetherapy, which uses natural viruses called #phage to target bacteria instead of antibiotics. We are working to develop new phage combinations, test the best way of giving them, and ensure the UK can produce phage at medical standards.

Thrilled to share that two of our papers with @jrpenades.bsky.social & GoogleDeepMind are now out in @cellpress.bsky.social 1️⃣Microbial piracy: tinyurl.com/yvf6t3b3 2️⃣AI co-scientist mirrors experimental science: tinyurl.com/2dym92kj @imperialcollegeldn.bsky.social @imperiallifesci.bsky.social

Please RT! Call for Fellows! If you’re a structural biologist and wanting to start your lab by applying for an external Fellowship then we at Imperial may be excited to host you. Synthetic biologists too.. Please submit expression of interest with details below 🙏 www.imperial.ac.uk/media/imperi...

Several years of work with several great collaborators, that combined computational biology, molecular microbiology, biochemistry, structural biology and mycology assay culminated in today's publication on discovery of novel bacterial toxins: www.nature.com/articles/s41...

Preparing for ETOX meeting in Bilbao with Yaara, Tracy, and Luke @lukeallsopp.bsky.social @proftracypalmer.bsky.social

This week I celebrate 10 years at FILM, the Facility for Imaging by Light Microscopy @imperialcollegeldn.bsky.social @imperialnhli.bsky.social Thank you to all the students, researchers and colleagues who used the facility and supported us! Here's to many more years of imaging 🥳🎉🔬

Today is Wear Yellow Day to raise awareness of and fundraise for Cystic Fibrosis. Teams of @janedaviescf.bsky.social, @lukeallsopp.bsky.social and Hughes in yellow. Researching towards unlocking a life unlimited for people with CF ‪@cysticfibrosis.org.uk www.cysticfibrosis.org.uk/get-involved...

Harriet Ellis, a postdoc in @lukeallsopp.bsky.social's Group, is uncovering how Pseudomonas aeruginosa – a key bacterial threat in cystic fibrosis – adapts & causes infection. 💛🦠 #CFweek Discover how her work could help fight lung infections 👇 blogs.imperial.ac.uk/nhli/2025/06...

#Myth busting #immunology, promoting #critical thinking and the awe of #science !!! Super enjoyed @dandavis101.bsky.social lecture at the @ri-science.bsky.social on Saturday!

Enjoyed @dandavis101.bsky.social lecture at @ri-science.bsky.social on Saturday night. Myth busting and promoting critical thinking with a clear passion for scientific discovery!!

White-nose disease in bats: The causative agent is not a single fungal species but 2 sympatric cryptic species with host specialization & geographically differentiated populations The source of the North American species has been traced to giant maze-caves of a region in Ukraine #MicroSky

“I was confident that macrophages would digest the microplastics and everything would be fine. I was truly surprised by what we found,” explained Adam Soloff, PhD, to Futura on his latest study on microplastics, which he presented at #ATS2025. Read more: www.futura-sciences.com/en/i-was-rea...

A bacterial regulatory uORF senses multiple classes of ribosome-targeting antibiotics elifesciences.org/articles/101...

I talked to 15 teachers/professors about how AI and ChatGPT is ruining their lives: www.404media.co/teachers-are...

Our researchers have created the first high-res map of the lung airway wall, revealing how cell organisation & interactions are disrupted in asthma 🫁 Published in @natimmunol.nature.com, it's a key step towards understanding the mechanisms that drive the disease www.imperial.ac.uk/news/264294/...

**NEW Doctoral Training Programme just launched!!** This exciting programme on Microbial Genomics for Health Protection is joint between @imibirmingham.bsky.social and UKHSA @ukhsa.bsky.social. 9 brilliant projects available!!

Brilliant Athena Swan Lecture by Dame Kate Bingham at @imperialcollegeldn.bsky.social ‘getting up in the morning and knowing your work will have an impact on someone- is my biggest driver’

UKRI's budget for 2025-26 confirmed...finally 5 months after spending review, and 1 day before financial year starts As @resprofnews.bsky.social has been reporting, it's less than flat cash (£8.8bn), despite DSIT's R&D budget rising Via @annamckie.bsky.social More details to come

Impactful study in @naturemedicine.bsky.social Eating more plants during pregnancy linked to lower neurodevelopmental disorders - #WOW www.nature.com/articles/s42...

Watching the US take a wrecking ball to science 💔 🤯 Reminder of the importance of doing science in the open. Put data, software, resources in public domain, where no single govt can erase them. This is our collective knowledge. Distributed data systems are essential. www.nature.com/articles/s41...

🏆 Research integrity consultant and image forensics expert @elisabethbik.bsky.social has uncovered fraudulent data in over 7,600 scientific papers and exposed the practices of ‘paper mills’ that produce counterfeit scientific articles. She is honoured with the €200K Individual Award. Congrats!

Principal Investigator / Group Leader post @quadraminstitute.bsky.social within the Microbes and Food Safety strategic programme - all research related to food safety and food spoilage. Unsure whether your research interests fit, contact us informally quadram.ac.uk/vacancies/gr...

From decoding deadly viruses to leading in #GlobalHealth crises—Prof Wendy Barclay’s impact is undeniable. Now, she’s the first woman appointed Regius Professor of Infectious Disease at @imperialcollegeldn.bsky.social. Learn more this Women at Imperial Week 👉 www.imperial.ac.uk/Stories/Wend...

If you are supervising an international student who is trying to write in their non-native language - tell them how awesome they are. They often feel incompetent, frustrated and even stupid. In reality they're really smart - just doing something very complicated. Tell them.

Funded 4-year #PhD in the exciting BBSRC NILAB program. @wwiem-qub.bsky.social Receive multidisciplinary training, develop #infection models and #AI image analysis to reveal bacterial & viral disease mechanisms & discover new antimicrobials. Fight #AMR Get in touch! Details: tinyurl.com/e5k6ptua

Congratulations to Luca Robinson for passing his viva today! Massive achievement #PhD @imperialnhli.bsky.social

Great to have Carmen visiting the lab from the Albesa lab! Some fun times and great science!

🚨Ready to be part of a pioneering microbiology lab that pushes the boundaries of scientific discovery? We have an **open postdoctoral position** in our lab, where we delve into the fascinating world of T6SS, effectors, mobile genetic elements, and everything in between! @erc.europa.eu -funded 🦠

“US President Donald Trump is taking a wrecking ball to science and to international institutions. The global research community must take a stand against these attacks.” Strong and welcome stance from @Nature www.nature.com/artic... 1/2

Establishment and characterization of persistent Pseudomonas aeruginosa infections in air-liquid interface cultures of human airway epithelial cells in Infect Immun from Susanne Häussler journals.asm.org/doi/10.1128/...

Latest out from the lab. Amazing amounts of #diversity in #T6SS #effectors #pseudomonas @imperialnhli.bsky.social www.imperial.ac.uk/news/260613/... www.evolbio.mpg.de/3804447/same... www.nature.com/articles/s41...

Looking for a #Research #Project #Manager with interest in #CF and #infection to work in a multidisciplinary team based out of @imperialnhli.bsky.social @imperialmed.bsky.social funding from @cftrustuk.bsky.social and #LifeArc www.imperial.ac.uk/jobs/search-...

Nucleic Acids Research has arrived on Bluesky! Follow them for the latest on biology and biochemistry of nucleic acids and proteins with which they interact. Run by scientists for scientists and a pioneer in Open Access. @narjournal.bsky.social

A fun collaboration with the Whitney, Prehna, and Bosis labs, in which we reveal the role of DUF2169 proteins: assisting PAAR-like domains in forming spike complexes and #T6SS assembly. 🦠 search.app/jDxaUi5yJK9B...

A deep dive into #T6SS effector diversity in #pseudomonas out now in @naturecomms.bsky.social lead by Antonia Habich from the Unterweger lab. Great science and great collaboration. www.nature.com/articles/s41...

Another fun collaboration with the van Kessel and @vibriosoup.bsky.social labs as part of our NSF-BSF grant. #Vibrio #T6SS 🦠 journals.asm.org/doi/10.1128/...

It's on! We've launched a call for applications after announcing our 2025 Grant Portfolio. Click here to learn more about this year’s grant offering and how to apply: www.the-microbiologist.com/news/applied...

📢 Apply now! We are recruiting an Associate Professor / Professor of Evolutionary Genomics to join our innovative research community! Find out more about the position and apply: https://buff.ly/4gIRTDf

💊🦠OUT NOW - comprehensive analysis of the propensity of ESKAPE pathogens to evolve resistance to new and in development antibiotics by Csaba Pal, Balint Kintses, Balazs Papp and colleagues. Dive in here... www.nature.com/articles/s41...

🏆 SPIE Directors' Award: Jess Wade, @imperialcollegeldn.bsky.social, Royal Society Univ. Research Fellow + Lecturer in Functional Materials For public engagement work in STEM, championing #WomenInSTEM, & tackling systemic biases surrounding race and gender. Read more: spie.org/news/jess-wa...

Sharing in #BlueSky a 2023 review on #T6SS that I loved co-authoring with my fantastic friend and collaborator @lukeallsopp.bsky.social He coined the catchy, musical first part of our title: "Killing in the Name of: T6SS Structure and Effector Diversity" Check it out: buff.ly/3Zzh0Rz #Microbiology

Great to see this paper published on Cpx signalling, LPS remodelling and colistin resistance. It is always a pleasure to work with my collaborators and friends @imperialcollegeldn.bsky.social @tcostalab.bsky.social @lukeallsopp.bsky.social and Gerald Larrouy Maumus. Check at doi.org/10.1038/s442...

Every two years, ISME celebrates the achievements of scientists who have substantially advanced the field of microbial ecology. If you know of outstanding members of the community worthy of an ISME Society Award, please fill in the nominations ballot by 31 Jan 2025👇🏼 isme-microbes.org/call-for-ism...

Great and busy times at @fillouxlab.bsky.social a few years back 😅. @lukeallsopp.bsky.social, @drlauranolan.bsky.social and I constructed a few TraDIS libraries to answer T6SS questions. Still remember the soundtrack of these days: Barry White 😂😂😂 over and over so the experiments were repetitive