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Excited to Salmonella effector SteE featured on the cover of EMBO reports www.embopress.org/journal/1469...

📣Preprint 📣 You want to degrade a protein in Gram-negatives? We have tackled this challenge! Detailed study of our Light-Activated Metal-Dependent Protein Degradation LAMP-D system in targeting and rescuing NDM-1 activity. What an amazing team effort 🫶🏻 doi.org/10.26434/che...

Second July issue is live. -> www.embopress.org/toc/14693178... featuring work by Teresa Thurston, Katrin Rittinger and co-workers @thurstonlab.bsky.social @katrinrittinger.bsky.social @dunnschool.bsky.social @imperialcollegeldn.bsky.social @crick.ac.uk. More: www.embopress.org/doi/full/10....

New from our lab @crick.ac.uk, in collaboration with the Enchev and Bukau labs. By studying a protein that is difficult to fold, we discover fascinating new mechanisms by which the ribosome supports protein biogenesis. www.biorxiv.org/content/10.1...

Very happy to share two back-to-back preprints of my postdoc work on bacterial NEL E3 ligases from my time in @katrinrittinger.bsky.social lab at @crick.ac.uk in collaboration with the ChemBio team at GSK (1/4)

How can a Salmonella effector change the specificity of a host kinase? SteE mediates kinase reprogramming via mimicry of conserved eukaryotic-like motifs- doi.org/10.1038/s443... Great collaboration with @katrinrittinger.bsky.social + big thanks to all authors & congrats to lead PDRA Ioanna Panagi!

After a great review process with @naturecomms.bsky.social, I'm so happy to share our work identifying inactive RING E3 #ubiquitin #pseudoligases in the TRIM protein family!! rdcu.be/ehlGW 🥳 🍾 🙌 @katmcphie.bsky.social @diegoesposito.bsky.social @katrinrittinger.bsky.social @crick.ac.uk

New preprint on how a minimal Salmonella kinase needs a host kinase to activate it. Work led by @timeshpillay.bsky.social and another great collaboration with @katrinrittinger.bsky.social @crick.ac.uk biorxiv.org/content/10.1...

Looking forward to the monthly on-line seminars organized by the Protein Modules Community @pmc-modularity.bsky.social and talks on SLiMs, systems biology, signaling, computational biology and much more. First talks by Dr Gogl @teamgogl.bsky.social and Dr Dionne @gingraslab.bsky.social.

Happy to share our new paper, out now in @commschem.bsky.social. Was great working with Aini and @katmcphie.bsky.social on this! We used chemoproteomics and HTC to find an enantioselective hit for OTUD7B. www.nature.com/articles/s42... @katrinrittinger.bsky.social @jtbush.bsky.social @crick.ac.uk

Excited to share a key part of my postdoctoral work from @crick.ac.uk and GSK, published in Nature Communications. A collaborative project to develop a high-throughput chemoproteomics platform for profiling cysteine-reactive fragments in native biological systems. www.nature.com/articles/s41...

If you are interested in 𝗔𝗰𝘁𝗶𝘃𝗶𝘁𝘆-𝗕𝗮𝘀𝗲𝗱 𝗣𝗿𝗼𝘁𝗲𝗶𝗻 𝗣𝗿𝗼𝗳𝗶𝗹𝗶𝗻𝗴, definitely consider the #ABPP2025 conference on March 30th to April 2nd, 2025, at The Francis Crick Institute. Registration deadlines have been updated. www.linkedin.com/posts/14th-i...