profaff.fr The new ProfAff database is up and running. Although there are still many things to improve, it is a major upgrade.

Bluesky, we need your help! Why does plain eGFP partially colocalize with actin filaments in cells? (No bleed-through, observed in multiple cell lines. Whole plasmid sequenced.) #FluorescenceFriday #Microscopy

The Quantitative Interactomics and Disease-Related Networks team at iBV (Nice, France) is recruiting a Postdoctoral Researcher with expertise in recombinant protein technologies and biochemistry.

The old ProfAff server served us well, but it’s time for an upgrade! Can’t wait to launch the new version from our new institute!

I am incredibly grateful to the ERC reviewers for their time and support. This recognition is a true honor and means a great deal to me. Excited to keep pushing forward the characterization of so-far unexplored motif-mediated protein–protein interactions!

GPT-5 seems like a pretty significant step towards PhD level. But a PhD-level researcher knows the literature, i.e., names of researchers and contents of key papers, much better. Or maybe it's only because we are working in a very niche field?

Today we got immediate desk rejection .... almost 8 weeks after submission! I think respectful journals could do better than this.

I’m thrilled to share that I have secured a permanent position within Section 20 of the CNRS. I will do my utmost to advance our understanding of the intricate interactome of transcription factors, an area of research I am deeply passionate about. 🎆

Congratulations to Boglarka for obtaining a CNRS permanent position! 🎉🥂 She will start a new line of research in the Gogl lab focusing on the quantitative interactomics and biophysics of protein-DNA interactions and their consequences on transcription regulation and chromatin organization.

We like our proteins pure. This is the first #mCherry purification in the new lab. The next ones will be less colorful, I am afraid...

We have a preprint for you EHD2 forms rings on caveolae necks, in contrast to most EHDs forming helices. We determined its structure on membranes and show that N-term acts as a spacer By Elena, Vasya @vasiliimikirtumov.bsky.social, Jeff &Oli Daumke www.biorxiv.org/content/10.1...

Snapped the first real Gogl team photo just before our pétanque championship. Spoiler: Bogi won! 🏆 #TeamGogl #newPI

Every time our team needs to order something important, the university’s response is basically...

Our brand new iD5 multi mode plate reader arrived from Molecular Devices! I cannot wait to see some data measured on it!

We are recruiting a junior group leader in computational structural biology. Spread the news! www.nature.com/naturecareer...

Our work on deriving protein-protein (functional) associations across different human tissues from proteomics data is now published. There is quite a lot in this paper, so I will just touch on a few highlights: www.nature.com/articles/s41...

Short interview hupo.org/Humans-of-HUPO

HUGE NEWS FOR THE TEAM - The most amazing Boglarka Zambo just got ranked at #6 in the CNRS N°20 concours. Seems like nothing is stopping her from getting a permanent position this year!

Our first paper of 2025 is now published in the Journal of the American Chemical Society! The Holdup Multiplex Assay is a powerful approach to measure the affinities of a peptide array against a protein of interest. We apply it for 14-3-3 proteins and PDZ domains. pubs.acs.org/doi/full/10....

Excited to share our latest preprint! We show how the non-catalytic epsilon DNA polymerase subunit, POLE2, binds to NPF motifs proteome-wide! 1/6 www.biorxiv.org/content/10.1...

Experiments are finally starting in the n̶e̶w̶ ̵l̶a̶b̶ construction site. #newPI

Looking forward to the monthly on-line seminars organized by the Protein Modules Community @pmc-modularity.bsky.social and talks on SLiMs, systems biology, signaling, computational biology and much more. First talks by Dr Gogl @teamgogl.bsky.social and Dr Dionne @gingraslab.bsky.social.

I just realized that the new Mendeley version does not work with LibreOffice under Linux anymore. Is there a good alternative? Zotero could work, but I am not a big fan of the 300 MB limit for online syncing. The only option is to pay for extra storage?

Join us for our new online seminar series, featuring two talks on protein modules every month! The first session kicks off at 6pm CET Feb 10 with Dr. Gergő Gógl and Dr. Ugo Dionne. Register to attend: tinyurl.com/register-pmc-seminar

Notes to myself: use a different reference for the next order. (Which may be due in the 2030s...)

A big step for the lab: we finally got a new centrifuge! It is basic, but it is on our floor and it is going to help us enormously! #newPI

New work outfit for the lab? 🤔

Don’t let your thesis look like this From the notes @amelierocks.bsky.social and I wrote about writing a thesis 🧪 github.com/KULL-Centre/...

Please give me ideas! How am I supposed to lift alone this 80kg shaker on top of a bench?

Hi BlueSky! We study molecular interaction networks by combining #biochemistry #proteomics and #bioinformatics. We are mostly curious about using our quantitative #systemsbiology approaches to characterize motif-mediated protein-protein interactions. #AcademicSky #HiSciSky