Fully funded PhD at @ukdri.ac.uk UCL, London, studying astrocyte microglia crosstalk and synaptic loss in Alzheimer disease. www.dementiaresearcher.nihr.ac.uk/job/phd-astr...

Yesterday's sunset 🌅 📷 Instagram | 12AtOxford

Had a great time representing the Human Brain Proteome Project during the "Friends of HUPO" social at #HUPO2025 last night. If you want to get involved, or simply hear more about the initiative, please get in touch 🧠

Two Postdoctoral Researcher Positions at University of Oxford to study Alzheimer’s disease using AI and iPSC models in the Translational Neuroscience Group. Closing date: 6th November www.dementiaresearcher.nihr.ac.uk/job/postdoc-...

#AAICNeuro www.dementiaresearcher.nihr.ac.uk/aaic-neurosc...

NEW: We’re honoured to be ranked number one in the Times Higher Education World University Rankings for the tenth consecutive year. 👏

Many thanks for the spotlight! "Trasna na dTonnta" (Across the Waves) is a great initiative from @drni.bsky.social for the Irish dementia research diaspora – a global community linking Irish dementia researchers on the island of Ireland to those undertaking research abroad #brainwaves 🧠🌊

University of Oxford seeks Research Associate to study extracellular vesicles and biomarkers in Parkinson’s disease using blood samples and iPSC based models. Closing date: 3rd October www.dementiaresearcher.nihr.ac.uk/job/research...

Excited contribute to this year’s lunch hour lecture program! It’s a free event and accessible to a non-specialist audience so please come and join me :)

ICYMI: New online! Trans-synaptic tau propagation in progressive supranuclear palsy

Blood Biomarkers: Testing for Alzheimer’s Disease Professor Jonathan Schott @jmschott.bsky.social (UCL) explains how blood tests are reshaping Alzheimer’s diagnosis. Clear, current and clinically relevant. Recorded at the Wessex Dementia Research Conference youtu.be/3fLl1Mzwbsk

A great story to be part of! Kudos to Mária, Anna, Anne, Sally and all of the team🧠

Encaenia 2025 @ox.ac.uk with my 🧠 buddy @stephfowler.bsky.social. It was great to see fellow Enniscorthy native Colm Tóibín receive the honorary degree of Doctor of Letters for his contribution to literature and journalism 💜💛

Fantastic start to the day here at the 3rd "Human Proteome and Health" Symposium at Rhodes House where Dr Katerina Gospodinova from the ARUK-ODDI and @cmd.ox.ac.uk discussed proteomic profiling of the #matrisome for use a novel therapeutic modality in #Alzheimers Disease 🧠 @arukthamesv.bsky.social

Our review is out now in Molecular & Cellular Proteomics! We discuss the latest advances in #HDX mass spectrometry to aid neurotherapeutic design & development in #Alzheimers, #Parkinsons and #ALS, providing molecular insights into protein aggregation pathways and therapeutic antibodies 🧠

External link live! Please share widely :-) WE ARE RECRUITING! 🥳 Are you an epidemiologist with strong quantitative skills and an interest in contributing to exciting research into the genetic architecture of vascular dementia? Come join our friendly and productive team at UCL! shorturl.at/aZ5Ua

Very pleased to share our review in @molneurodegen.bsky.social, assessing evidence for #ExtracellularVesicle associated #TDP43. We highlight knowledge gaps relating to its biomarker usage and possible involvement in seeding of templated aggregation in #ALS, #FTD and #LATE. doi.org/10.1186/s130...

Check out our June issue! www.nature.com/neuro/volume...

Could blood tests reduce diagnostic delays for dementia? Experts weigh in on our podcast – don’t miss this timely discussion with @ajh1269.bsky.social‬ @ukdri.ac.uk‬ Dr Mark Roskey from Quanterix and Dr Jay Amin, University of Southampton

Keeping up with the literature is essential. But so is devoting time to developing your own scientific ideas, writes Sheena Josselyn. #neuroskyence www.thetransmitter.org/craft-and-ca...

🚨MRC Research Fellow Vacancy: Studying microglial ageing utilising iPSC-based cell biology, screening, biochemistry, genomics, imaging & bioinformatics @dervissalih1.bsky.social, UK DRI at UCL 🗓️ Closing 26 June 👉 www.ucl.ac.uk/work-at-ucl/...

Join the UKDRI at UCL in the Salih Lab to explore how glial-specific longevity genes affect ageing and Alzheimer’s, using iPSC models, genomics, and molecular biology @ukdri.ac.uk @dervissalih1.bsky.social Closing date: 26th June www.dementiaresearcher.nihr.ac.uk/job/research...

New research led by Dr Frances Wiseman (UK DRI at ‪@uclqsion.bsky.social‬) demonstrates that levels of Apolipoprotein E (APOE), a protein implicated in Alzheimer’s, are increased in the brains of individuals with Down syndrome & Alzheimer's 🧠 Read the full story👉https://buff.ly/5WnCY4s

High-Resolution Spatial Profiling of Microglia Reveals Proximity Associated Immunometabolic Reprogramming in Alzheimers Disease https://www.biorxiv.org/content/10.1101/2025.05.16.654329v1

The @ukdri.ac.uk at UCL is recruiting a lab manager to oversee daily operations and contribute to pioneering neuro-glia-immune research in ageing and neurodegeneration. Closing date: 21st May www.dementiaresearcher.nihr.ac.uk/job/research...

A nice read and ICYMI here is our cited paper from the end of last year on the microglia contribution to Familial British Dementia: link.springer.com/article/10.1...

'Evidence suggesting that #microglia make #amyloid from neuronally expressed APP: a hypothesis' John Hardy & Patrick Lewis molecularneurodegeneration.biomedcentral.com/articles/10....

MAPT Splicing Modulators as a Therapeutic Strategy for Tauopathies https://www.biorxiv.org/content/10.1101/2025.05.06.652428v1

New online: Chimeric deubiquitinase engineering reveals structural basis for specific inhibition of the mitophagy regulator USP30

"Science is an investment. We will put forward a new 500 million package for 2025-2027 to support the best and the brightest researchers and scientists from Europe and around the world." — President @vonderleyen.ec.europa.eu at the ‘Choose Europe for Science' event at La Sorbonne 🇫🇷

Wendy is an excellent scientist. I would highly encourage you to apply!

New research led by @marcaurelbusche.bsky.social has found that tau specifically disrupts a certain type of electrical activity in the hippocampus in Alzheimer's🧠 The findings unlock a key piece of the puzzle in understanding how toxic tau drives memory problems👏👉 buff.ly/yx8Rdk6

How does the brain repair myelin after injury? We mapped the full cellular choreography of white matter repair using snRNA-seq + Slide-seqv2, uncovering a type I interferon-driven glial program that recruits lymphocytes to promote remyelination. www.biorxiv.org/content/10.1... Details below 👇

It's been a couple of weeks since finishing the Paris Marathon to raise funds for dementia research. I have finally recovered! What a day! Shout out to my running buddy Tika Malla and the ARUK cheer team who came to France. There's still some time to donate to our fundraising here shorturl.at/ujnKc

Sending good luck to wishes to everyone running in the London and Manchester Marathon today! Let’s give help and hope to people affected by dementia, one mile at a time. Go Team Alzheimer's Society! 🎉

Go, Go, Go!

Only 16 days to go until Paris! Please share the link and donate to help me raise urgent funds for dementia research 👇🏻 www.justgiving.com/page/26miles...

Happy to announce that I'm now a Research Fellow of Green Templeton College, University of Oxford!

Proudly flying the @alzresearchuk.bsky.social flag today at the Teddy Hall Relays in Oxford @cmd.ox.ac.uk @ndm.ox.ac.uk #foracure

Now is the moment!! If you'd like to come and do a PhD with me in sunny Dundee then I have not 1 but 2 funded PhD positions in my lab looking at #ApoE. Please reach out with any questions! Come do science with us, it'll be fun! www.dundee.ac.uk/phds/opportu... www.dundee.ac.uk/phds/opportu...

We're pleased to introduce Donatella Di Rienzo from the @alzheimersresearchuk.org Drug Discovery Institute in Oxford. Donna joined us on our podcast this week to share her highlights from last weeks conference #ARUKConf25 www.dementiaresearcher.nihr.ac.uk/profile-dona...

Dr Amanda Heslegrave @ajh1269.bsky.social is seeking a Research Assistant to join her team workin in the UK DRI / UCL Fluid Biomarker Lab on 'UK-TBI REpository and data PORTal Enabling discoveRy' @ukdri.ac.uk - Closing date: 9th March www.dementiaresearcher.nihr.ac.uk/job/research...

Get ready for #RareDiseaseDay which is coming Friday 28 February! We'll be sharing a lot of interesting and exciting things on the day, so stay tuned to our socials. You can learn more about the day and what it means here ow.ly/tE6a50V6MoM #ShowYourStripes @rarediseasesint.bsky.social #PSP #CBD

Global citizens: 105 different nationalities are represented among staff at #OxfordMedSci.

Had a great time at #ARUKConf2025 hearing about exciting new directions for dementia research in the UK and beyond. It's always a great opportunity to catch up with old friends and colleagues and to make some new ones! #foracure

A dark, wet and cold start, but well worth it! #foracure

VOLUNTEER: The POLARIS-AD research study is for people with early signs of Alzheimer’s disease and mild cognitive impairment. It tests a new investigational medication to see if it can slow or reverse early Alzheimer’s symptoms. Learn more: Dementia.Research@ox...

I've #justsponsored Selina Wray, who's fundraising for Alzheimer's Research UK on @JustGiving. Donate now: www.justgiving.com/page/selina-...

Nature Medicine: A man with an early-onset Alzheimer’s gene and a brain full of amyloids should have developed dementia by 50, but showed no symptoms at 70! 👀 Interestingly, the typical tau changes were missing, strengthening argument that tau, not amyloid, drives cognitive decline.

NEW: Oxford University has been ranked first in the world in the @timeshighered.bsky.social Subject Rankings for Medicine and Computer Science. Oxford leads in Medicine for the 14th consecutive year and in Computer Science for the 7th. More info ⬇️