Gen Z and Millennials: In ten years when we’re still without a cure and you’re caring for your parents, remember what he did.

Friday SCOOP: DOGE is now at the Department of Veterans Affairs, where a DOGE operative appears to be trying to use an AI tool to write code for the agency's systems, among other proposals. If you're a gov/tech worker and want to talk, I'm on Signal at vittoria89.82 www.wired.com/story/doge-d...

💡Curious about intrinsically disordered regions in your proteins? Jalview's got answers - FOUR of them, infact! Many disease-associated proteins, including those involved in neurodegenerative disorders (e.g., Alzheimer's and Parkinson's) and cancer, contain IDRs.

“Virtually no one thinks that we are making the best use of scientists’ time.” DOGE, however, isn’t fixing that—it’s cancelling grants, firing scientists, and causing chaos. If efficiency were the goal, we wouldn’t be here, argues @stuartbuck.bsky.social. buff.ly/Pairzxt

This is unconscionable! Subjecting eminent scientists to this uncertainty is crazy!!! How can DOGE with their ‘coding errors’ be in charge of the US economy?! I hope each of these actions will be the subject of a punitive lawsuit collectively and individually

"more than 100 million people have died of tuberculosis because the drugs are not widely available in many parts of the world. The most proximate cause of contemporary tuberculosis deaths is not M. tuberculosis, but Homo sapiens." 🧪 www.theatlantic.com/health/archi... bookshop.org/p/books/unti...

Add: the mass extinction of species, including key species, which could lead to extinction of the human species. No amount of survivalist training will make up for lack of resources. No billions of dollars can rewild a key species if it has no habitat. We can adapt, but we have our limits. 🌎🧪

🧪⚛️ My obituary for Sam Edwards, published in PNAS is open access www.pnas.org/doi/full/10....

A puntito de empezar la 2da Asamblea de la Conexión @bcbhubcsic.bsky.social !!!! Nos esperan 3 días intensos de encuentros, ciencia y planes para una Biología Computacional y Bioinformática en expansión!! @csic.es @csic-vaact.bsky.social

Second meeting for the @bcbhubcsic.bsky.social starts with an introduction by @anaconesa.bsky.social. Three wonderful days in front of us to enhance the wonderful #bioinformatics and #computational_biology community at @csic.es.

Kickking off the second day our @bcbhubcsic.bsky.social meeting with scientific sesions with Victor Sánchez Gaya, presenting POSTRE, a tool to predict the funcional impact of pstructural variants @hitseq.bsky.social @ibv-csic.bsky.social @csic-vaact.bsky.social

Next, Ana Martinez and Carmen Gil from @cib-csic.bsky.social presenting how to use a consortium of AI tools for drug design, with múltiple applicatons in the clínic @bcbhubcsic.bsky.social @csic-vaact.bsky.social #2AsambleaBCBHub

Patricia Mingo, from INIA-CSIC now explaining their lipidomics and transcriptomics work to find new treatments to combat West Nilo Virus, a growing threat in Spain. @bcbhubcsic.bsky.social @i2sysbio.bsky.social @csic-vaact.bsky.social #2AsambleaBCBHub

Enjoing the next talk by @ramalok.bsky.social from @ICMCSIC exploring the diversity of sea microorganism at Mediterranean trajectories by metagenomics-based population genomics @bcbhubcsic.bsky.social @hitseq.bsky.social @longtrec.bsky.social @csic-vaact.bsky.social

insightful talk by Juan Fdez Recio: “using molecular dynamics is better than static models to predict the impact of mutations on Protein Protein Interactions” @bcbhubcsic.bsky.social @csic-vaact.bsky.social #2AsambleaBCBHub

The picture of the @bcbhubcsic.bsky.social, the Bioinformatics and Computational Biology family of @csic.es @csic-vaact.bsky.social @i2sysbio.bsky.social @ibv-csic.bsky.social @iscb.bsky.social

I love this talk by Alejandro Dominguez from @cbgpmadrid.bsky.social who explains how to predict microbial metabolite -host protein interactions @bcbhubcsic.bsky.social @csic-vaact.bsky.social

¿Aún no conoces al Grupo de Nutrigenómica del IATS del CSIC? Te invitamos a conocerles en nuestro Canal de YouTube youtu.be/S9VsVHHDsys

Followed by Javier de las Rivas (IBMCC) describing in detail his approach to single cell and deconvolution in cancer samples.

Daniel Rico (CABIMER) shows a very nice introduction to epigenetics landscapes in cancer cells with focus on cell identity.

Second day of the second BCB.hub meeting. A very intense day full of interesting stuff. First in the morning Victor Sanchez from IBBTEC showcasing the performance of their POSTRE tool to diagnose TAD-related disease.

The last session started with (Gonzalo Colmenarejo, IMDEA FOOD) about computational design of metabolites to create new drugs

then the (online) description of approaching food allergens by Mónica Carrera (IIM).

And the closing talk by Arnau Montagud (I2SYSBIO) describing how multi-scale approach modeling can lead to understand complex biological processes.

The flashtalks sessions provide an interesting overview of very interesting approaches to a variety of topics.

Summary: #2ndBCB.HUB meeting, a great day full of nice scientific presentations with lots of interactions and networking. A picture of the big computational biology community at CSIC @csicdivulga.bsky.social, and the Executive board of the Hub.

Rise your hand if this has happened to you! 🙋🏻‍♀️

Wow. "NIH" canceled my co-mentored (with Dave Sulzer) PhD student's F31 funding. His work is on understanding the genetics and neuroscience of language learning disorders. F31 provides no indirect $ to Columbia, just pays his salary. Not that it should matter, but he's an American citizen. W.T.F.

Hearing from a source: "A friend at NCI lost 3 outstanding staff (their words) and tweeted about it. She was suspended for 2 days. No idea how her tweet was flagged." This is for all the people asking us why it's hard to tell what's happening at NIH. Retaliation is real.

This is what NCI scientists now have to face approval and probably censorship for by the DOGE twinks if they want to publish. www.propublica.org/article/nati...

It is raining a lot in Seville

'What those of us not cocooned in our corner offices see is that Musk let a bunch of Dunning-Kruger kids — too incompetent to realize that they’re incompetent — loose on federal agencies, where they began firing workers without trying to understand what these workers do' @pkrugman.bsky.social

Have FUN!!!!! #Anonymous

Some federal workers are going back to work. The USDA has been ordered to temporarily give over 5,000 workers their jobs back. Dozens of CDC scientists have been reinstated after being illegally fired. The National Science Foundation has rehired half of the workers it fired.

Sobre el delicado momento de la conservación de los datos biomedicos en tiempos inciertos "Es imperativo completar los sistemas y procesos que eviten dependencias críticas, adoptando tecnologías que permitan la creación de entornos colaborativos y descentralizados" elpais.com/ciencia/2025...

Check it out! The #TED functional domains are now at @pdbeurope.bsky.social , ebi.ac.uk/about/news/u..., @nbordin.bsky.social

Imposter Syndrome & The Perfectionist Trap 🎭 More in Alt Text. #ImposterSyndrome #Perfectionism #PhDLife #AcademicWriting #Research #Productivity #WorkSmart #MindsetMatters #GradSchool #ScienceCommunication 🧪

Looking for a PhD fellowship at one of the leading life science research institutions of the world? The Biozentrum provides a stimulating and inspiring research experience for experimental and computational life scientists. #lifesciences 🧪 #switzerland #basel

In case you were wondering, ASM did NOT sign, AISES and SACNAS did sign. Disappointed , not surprised 🧪🦠

Against the Odds: Women Pioneers of Science by John Gribbin & Mary Gribbin - if you’re not going to read the book that highlights how women have been considered unsuitable as researchers for reasons other than their ability then read this book review 🧪 #WomeninSTEM www.nature.com/articles/d41...

We are hiring! Our lab is recruiting a bioinformatician with experience in microbiome data analysis. More details here: jobrxiv.org/job/centro-d... Deadline for applications is April 1st. Please share!

The ~100 NIH study sections cancelled so far. Musk, Milei et al. We are witnessing a scary global trend: a war declaration to Science. docs.google.com/spreadsheets...

#yeah!!! This great lab keep on delivering tools for the plp. Thx!! t.co/XB2M1voL3a

🦋 The #genome of Coenonympha oedippus, the false ringlet butterfly, is here! This new reference genome provides crucial insights into ecological adaptation and conservation of this #endangered species. 👉 www.biorxiv.org/content/10.1... #Genomics #Biodiversity @biogeneurope.bsky.social

¿Quién fue Margaret O Dayhoff? En el centenario de su nacimiento, recupero una pieza que escribí hace unos años sobre ella. www.upo.es/diario/11-fe...

Calling all bioRxiv affiliates - bat signal is up as we have a big backlog. If you have time to screen some papers, we'd be eternally grateful! 🙏

Recommendations by Acs about using #AI for scientific writing pubs.acs.org/doi/epdf/10....

This also, very interesting www.nature.com/articles/s41...