Nanopore-based sequencing of active DNA replication reveals key principles of metazoan replication fork progression, origin and termination sites https://www.biorxiv.org/content/10.1101/2025.09.26.678856v1

PIWI clade Argonautes are essential for transposon silencing. Without them, animals are sterile due to massive transposon activity. But how does piRNA-guided target interaction translate into silencing? PhD student Júlia Portell Montserrat has an intriguing answer www.cell.com/molecular-ce...

How cells lock down “jumping genes”: Researchers from IMBA and IMP identify the first protein interactions that trigger PIWI–piRNA–mediated transposon silencing, using AlphaFold predictions, genetics, biochemistry and cell biology. Read more: www.viennabiocenter.org/about/news/t...

Excited to share my postdoc work, out on bioRxiv today! Histones package DNA into nucleosomes to form the building blocks of chromatin, but how modular and programmable is this system? 1/9

Are you someone who has been or could be affected by imminent ICE raids in Chicago? Do you have friends, family members or neighbors who have been or could be? If you have information you can share, please reach out to @melissa-sanchez.bsky.social on Signal or WhatsApp at 872-444-0011.

Tissue 'tectonic' collision is detrimental, but flies found two distinct solutions! Gratifying and grateful to be included in this collective effort, w/ Steffen Lemke, to crack the (or 'a') code of #cephalicfurrow, now out in @nature.com, all with @paveltomancak.bsky.social at the helm. (1/9)

We are all super happy and proud to see our work on the function and evolution of the #cephalic #furrow published in @nature.com. Let me say a few things about the background and history of this work on the #Evolution_of_Morphogenesis (1/12)

Priyom's preprint is out on biorxiv. See below for a detailed thread. In a nutshell, she has discovered and characterized the oscillator that times notochord and spine segmentation in zebrafish. Turns out that there are uniform Erk oscillations across the entire tissue that act as timekeepers!

I have NIGMS R35, impact score 12 NIHGRI R21, 4th percentile NHGRI R01, 7th percentile (co-I) and it seems like none will be funded. 0/3. PO (who has been very helpful) said "Unfortunately, I do not expect this application will be selected for funding in FY25." 😭

Extremely excited to share that I’m joining Columbia University @columbiauniversity.bsky.social as an Assistant Professor! We will explore how the mobile genome works—how transposons shape us, our DNA and how they can be harnessed to build useful technologies. #NewPI #RNAsky #TEsky thawanilab.org

New paper on the role of H3K4me3 at enhancers! We (led by Haoming Yu) used dCas9 epigenome editing to add H3K4me3 to intergenic enhancers. This was (1) sufficient to turn up transcription at open, active regions and (2) has no effect on target gene transcription. genesdev.cshlp.org/content/earl...

NU Professor Jane Wu’s daughter and colleagues called her an “outstanding scientist” dedicated to “the greater good.” Before she died in July 2024, she was investigated, then cleared by the government. She still lost her funding and lab space. — Reported by William Tong

Congrats to UNC Biology professor En Yang, named one of this year's Pew Scholars. Yang uses zebrafish as an experimental model to study the neural pathways involved in learning and memory formation. 1/n college.unc.edu/2025/08/en-y...

Big congrats to our postdoc @mary-flores.bsky.social, who's among the 2025 Pew Latin American Fellows! 🐟🧬🫀🧪 Onwards, always. #PewLatinAmericanFellows #zebrafish #PILife #PostdocLife #devbio @cudevbio.bsky.social

Snails with human-like eyes?! Published in @natcomms.nature.com, the @planaria1.bsky.social & @accorsi-alice.bsky.social Labs have established apple snails as a novel model for studying vision restoration. They have complex camera-type eyes & the ability to regrow them in 28 days: bit.ly/4mvaxkq

The Parker Lab at UNC Biology is hiring a postdoc to work on insect–microbe interactions. Support available for multiple years from startup; we are open to a range of project ideas. Come join us to study symbiosis in a supportive, collaborative environment! unc.peopleadmin.com/postings/303...

"[Our] journals provide a rapid and informed assessment by expert scientific editors (on average, within 4 days)." Friends, it will be 2 weeks tomorrow. 😢

Excited to share a new preprint from the lab! This (doi.org/10.1101/2025...) and an earlier one (doi.org/10.1101/2025...) mark my lab's first steps into studying how Polycomb modifications get established in early Drosophila development. 🧵 1/10

Happy to announce a new preprint from my lab looking in to the establishment of polycomb domains in early fly development and contributions from pioneer factors Zelda and GAGA-factor.

Excited to share the bulk of my postdocotoral work from the @ditalialab.bsky.social on how cells interpret dynamic morphogen signaling during development! Many thanks to our collaborators & coauthors @shelbyflies.bsky.social, Massimo Vergassola, Jacqueline Janssen, and Anna Chao.

www.nature.com/articles/s41... (1/n) Ever wonder how transcription factors locate, "invade," and activate their enhancers during cell fate acquisition? 🧬🚀 Check out our latest collaborative work with the Soufi lab, now published in @Nature

First post on bsky. We've updated our preprint about the change in the histone H3 variant on chromatin during Zygotic Genome Activation. Thanks to new experiments by Anusha, it seems like our initial, simplistic idea that the embryo "ran out" of H3 was not right. www.biorxiv.org/content/10.1...

Please spread the word! We are looking for postdoc(s) interested in quantitative problems in Development and Regeneration. Previous experience in quantitative biology is not required. We will support you and provide a great training environment if you are committed to learn new things.

Very proud to share the latest preprint from my lab by Ellie Degen and co. Here Ellie shows that a concentration threshold in the Bcd morphogen gradient is determined by competition with nucleosomes. Great mix of math, imaging, and genomics!